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Items: 12

Select item 104354601.

Ligand recognition and G protein coupling of the human itch receptor MRGPRX1

Lulu Guo, Yumu Zhang, Guoxing Fang, Lu Tie, Yuming Zhuang, Chenyang Xue, Qi Liu, Minghui Zhang, Kongkai Zhu, Chongzhao You, Peiyu Xu, Qingning Yuan, Chao Zhang, Lei Liu, Naikang Rong, Shengxuan Peng, Yuan Liu, Chuanzheng Wang, Xin Luo, Zongyao Lv, Dongwei Kang, Xiao Yu, Cheng Zhang, Yi Jiang, Xinzhong Dong, Jiuyao Zhou, Zhongmin Liu, Fan Yang, H. Eric Xu, Jin-Peng Sun

Nat Commun. 2023; 14: 5004. Published online 2023 Aug 17. doi: 10.1038/s41467-023-40705-z

PMCID:: PMC10435460

Abstract Article PDF–3.3M

Select item 102869972.

Mechanism of agonist-induced activation of the human itch receptor MRGPRX1

Bing Gan, Leiye Yu, Haifeng Yang, Haizhan Jiao, Bin Pang, Yian Chen, Chen Wang, Rui Lv, Hongli Hu, Zhijian Cao, Ruobing Ren

PLoS Biol. 2023 Jun; 21(6): e3001975. Published online 2023 Jun 22. doi: 10.1371/journal.pbio.3001975

PMCID:: PMC10286997

Abstract Article PDF–2.1M

Select item 66596833.

BAM8-22 and its receptor MRGPRX1 may attribute to cholestatic pruritus

Babina Sanjel, Han-Joo Maeng, Won-Sik Shim

Sci Rep. 2019; 9: 10888. Published online 2019 Jul 26. doi: 10.1038/s41598-019-47267-5

PMCID:: PMC6659683

Abstract Article PDF–3.2M

Select item 53475604.

Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain

Zhe Li, Pang-Yen Tseng, Vinod Tiwari, Qian Xu, Shao-Qiu He, Yan Wang, Qin Zheng, Liang Han, Zhiping Wu, Anna L. Blobaum, Yiyuan Cui, Vineeta Tiwari, Shuohao Sun, Yingying Cheng, Julie H. Y. Huang-Lionnet, Yixun Geng, Bo Xiao, Junmin Peng, Corey Hopkins, Srinivasa N. Raja, Yun Guan, Xinzhong Dong

Proc Natl Acad Sci U S A. 2017 Mar 7; 114(10): E1996–E2005. Published online 2017 Feb 21. doi: 10.1073/pnas.1615255114

PMCID:: PMC5347560

Abstract Article PDF–1.7M

Select item 80647495.

Pruriception and neuronal coding in nociceptor subtypes in human and nonhuman primates

Amanda Klein, Hans Jürgen Solinski, Nathalie M Malewicz, Hada Fong-ha Ieong, Elizabeth I Sypek, Steven G Shimada, Timothy V Hartke, Matthew Wooten, Gang Wu, Xinzhong Dong, Mark A Hoon, Robert H LaMotte, Matthias Ringkamp

eLife. 2021; 10: e64506. Published online 2021 Apr 23. doi: 10.7554/eLife.64506

PMCID:: PMC8064749

Abstract Article PDF–3.5M

Select item 57945326.

Vemuri B. Reddy, Ehsan Azimi, Lei Chu, Ethan A. Lerner

J Invest Dermatol. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: J Invest Dermatol. 2018 Feb; 138(2): 461–464. Published online 2017 Oct 4. doi: 10.1016/j.jid.2017.05.042

PMCID:: PMC5794532

Abstract Article PDF–1.4M

Select item 56555167.

Activation of mas-related G-protein–coupled receptors by the house dust mite cysteine protease Der p1 provides a new mechanism linking allergy and inflammation

Vemuri B. Reddy, Ethan A. Lerner

J Biol Chem. 2017 Oct 20; 292(42): 17399–17406. Published online 2017 Aug 2. doi: 10.1074/jbc.M117.787887

PMCID:: PMC5655516

Abstract Article PDF–1.9M

Select item 29894058.

Sensory neuron-specific GPCRs Mrgprs are itch receptors mediating chloroquine-induced pruritus

Qin Liu, Zongxiang Tang, Lenka Surdenikova, Seungil Kim, Kush N. Patel, Andrew Kim, Fei Ru, Yun Guan, Hao-Jui Weng, Yixun Geng, Bradley J. Undem, Marian Kollarik, Zhou-Feng Chen, David J. Anderson, Xinzhong Dong

Cell. Author manuscript; available in PMC 2010 Nov 21.

Published in final edited form as: Cell. 2009 Dec 24; 139(7): 1353–1365. Published online 2009 Dec 10. doi: 10.1016/j.cell.2009.11.034