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Select item 99358931.

The ULK3 kinase is a determinant of keratinocyte self-renewal and tumorigenesis targeting the arginine methylome

Sandro Goruppi, Andrea Clocchiatti, Giulia Bottoni, Emery Di Cicco, Min Ma, Beatrice Tassone, Victor Neel, Shadhmer Demehri, Christian Simon, G. Paolo Dotto

Nat Commun. 2023; 14: 887. Published online 2023 Feb 16. doi: 10.1038/s41467-023-36410-6

PMCID:: PMC9935893

Abstract Article PDF–5.9M

Select item 26663402.

Autophagy mediates the mitotic senescence transition

Andrew R.J. Young, Masako Narita, Manuela Ferreira, Kristina Kirschner, Mahito Sadaie, Jeremy F.J. Darot, Simon Tavaré, Satoko Arakawa, Shigeomi Shimizu, Fiona M. Watt, Masashi Narita

Genes Dev. 2009 Apr 1; 23(7): 798–803. doi: 10.1101/gad.519709

PMCID:: PMC2666340

Abstract Article PDF–710K

Select item 44750613.

ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins

Anna Caballe, Dawn M Wenzel, Monica Agromayor, Steven L Alam, Jack J Skalicky, Magdalena Kloc, Jeremy G Carlton, Leticia Labrador, Wesley I Sundquist, Juan Martin-Serrano

eLife. 2015; 4: e06547. Published online 2015 May 26. doi: 10.7554/eLife.06547

PMCID:: PMC4475061

Abstract Article PDF–6.4M

Select item 56161854.

The Ulk3 kinase is critical for convergent control of cancer associated fibroblast activation by CSL and Gli

Sandro Goruppi, Maria-Giuseppina Procopio, Seunghee Jo, Andrea Clocchiatti, Victor Neel, G. Paolo Dotto

Cell Rep. Author manuscript; available in PMC 2017 Sep 27.

Published in final edited form as: Cell Rep. 2017 Sep 5; 20(10): 2468–2479. doi: 10.1016/j.celrep.2017.08.048

PMCID:: PMC5616185

Abstract Article PDF–2.0M

Select item 34826845.

Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM

N Amin, E Byrne, J Johnson, G Chenevix-Trench, S Walter, I M Nolte, kConFab Investigators, J M Vink, R Rawal, M Mangino, A Teumer, J C Keers, G Verwoert, S Baumeister, R Biffar, A Petersmann, N Dahmen, A Doering, A Isaacs, L Broer, N R Wray, G W Montgomery, D Levy, B M Psaty, V Gudnason, A Chakravarti, P Sulem, D F Gudbjartsson, L A Kiemeney, U Thorsteinsdottir, K Stefansson, F J A van Rooij, Y S Aulchenko, J J Hottenga, F R Rivadeneira, A Hofman, A G Uitterlinden, C J Hammond, S-Y Shin, A Ikram, J C M Witteman, A C J W Janssens, H Snieder, H Tiemeier, B H R Wolfenbuttel, B A Oostra, A C Heath, E Wichmann, T D Spector, H J Grabe, D I Boomsma, N G Martin, C M van Duijn

Mol Psychiatry. 2012 Nov; 17(11): 1116–1129. Published online 2011 Aug 30. doi: 10.1038/mp.2011.101

PMCID:: PMC3482684

Abstract Article PDF–1.1M

Select item 29433186.

Dual Function of UNC-51-like Kinase 3 (Ulk3) in the Sonic Hedgehog Signaling Pathway

Alla Maloverjan, Marko Piirsoo, Lagle Kasak, Lauri Peil, Torben Østerlund, Priit Kogerman

J Biol Chem. 2010 Sep 24; 285(39): 30079–30090. Published online 2010 Jul 19. doi: 10.1074/jbc.M110.133991

PMCID:: PMC2943318

Abstract Article PDF–2.1M

Select item 67367147.

Phosphorylation of Ci/Gli by Fused family kinases promotes Hedgehog signaling

Yuhong Han, Bing Wang, Yong Suk Cho, Jian Zhu, Jiang Wu, Yongbin Chen, Jin Jiang

Dev Cell. Author manuscript; available in PMC 2020 Sep 9.

Published in final edited form as: Dev Cell. 2019 Sep 9; 50(5): 610–626.e4. Published online 2019 Jul 3. doi: 10.1016/j.devcel.2019.06.008

PMCID:: PMC6736714

Abstract Article PDF–3.0M

Select item 30716308.

Genome-Wide Meta-Analysis Identifies Regions on 7p21 (AHR) and 15q24 (CYP1A2) As Determinants of Habitual Caffeine Consumption

Marilyn C. Cornelis, Keri L. Monda, Kai Yu, Nina Paynter, Elizabeth M. Azzato, Siiri N. Bennett, Sonja I. Berndt, Eric Boerwinkle, Stephen Chanock, Nilanjan Chatterjee, David Couper, Gary Curhan, Gerardo Heiss, Frank B. Hu, David J. Hunter, Kevin Jacobs, Majken K. Jensen, Peter Kraft, Maria Teresa Landi, Jennifer A. Nettleton, Mark P. Purdue, Preetha Rajaraman, Eric B. Rimm, Lynda M. Rose, Nathaniel Rothman, Debra Silverman, Rachael Stolzenberg-Solomon, Amy Subar, Meredith Yeager, Daniel I. Chasman, Rob M. van Dam, Neil E. Caporaso

PLoS Genet. 2011 Apr; 7(4): e1002033. Published online 2011 Apr 7. doi: 10.1371/journal.pgen.1002033

PMCID:: PMC3071630

Abstract Article PDF–281K

Select item 30051309.

Discovery and replication of novel blood pressure genetic loci in the Women’s Genome Health Study

Jennifer E. HO, Daniel LEVY, Lynda ROSE, Andrew D. JOHNSON, Paul M RIDKER, Daniel I. CHASMAN

J Hypertens. Author manuscript; available in PMC 2012 Jan 1.

Published in final edited form as: J Hypertens. 2011 Jan; 29(1): 62–69. doi: 10.1097/HJH.0b013e3283406927

PMCID:: PMC3005130

Abstract Article PDF–353K

Select item 299871210.

Genome-wide association study of blood pressure and hypertension

Daniel Levy, Georg B. Ehret, Kenneth Rice, Germaine C. Verwoert, Lenore J. Launer, Abbas Dehghan, Nicole L. Glazer, Alanna C. Morrison, Andrew D. Johnson, Thor Aspelund, Yurii Aulchenko, Thomas Lumley, Anna Köttgen, Ramachandran S. Vasan, Fernando Rivadeneira, Gudny Eiriksdottir, Xiuqing Guo, Dan E. Arking, Gary F. Mitchell, Francesco U.S. Mattace-Raso, Albert V Smith, Kent Taylor, Robert B. Scharpf, Shih-Jen Hwang, Eric J.G. Sijbrands, Joshua Bis, Tamara B. Harris, Santhi K. Ganesh, Christopher J. O’Donnell, Albert Hofman, Jerome I. Rotter, Josef Coresh, Emelia J. Benjamin, André G. Uitterlinden, Gerardo Heiss, Caroline S. Fox, Jacqueline C.M. Witteman, Eric Boerwinkle, Thomas J. Wang, Vilmundur Gudnason, Martin G. Larson, Aravinda Chakravarti, Bruce M. Psaty, Cornelia M. van Duijn

Nat Genet. Author manuscript; available in PMC 2010 Dec 8.

Published in final edited form as: Nat Genet. 2009 Jun; 41(6): 677–687. Published online 2009 May 10. doi: 10.1038/ng.384

PMCID:: PMC2998712

Abstract Article PDF–624K

Select item 334092611.

Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk

The International Consortium for Blood Pressure Genome-Wide Association Studies

Nature. Author manuscript; available in PMC 2012 May 1.

Published in final edited form as: Nature. 2011 Oct 6; 478(7367): 103–109. Published online 2011 Sep 11. doi: 10.1038/nature10405

PMCID:: PMC3340926

Abstract Article PDF–757K

Select item 765717912.

Genome‐wide association study of chemotherapeutic agent‐induced severe neutropenia/leucopenia for patients in Biobank Japan

Siew‐Kee Low, Suyoun Chung, Atsushi Takahashi, Hitoshi Zembutsu, Taisei Mushiroda, Michiaki Kubo, Yusuke Nakamura

Cancer Sci. 2013 Aug; 104(8): 1074–1082. Published online 2013 Jun 10. doi: 10.1111/cas.12186

PMCID:: PMC7657179

Abstract Article PDF–225K

Select item 848687813.

Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity

Fabien Thery, Lia Martina, Caroline Asselman, Yifeng Zhang, Madeleine Vessely, Heidi Repo, Koen Sedeyn, George D. Moschonas, Clara Bredow, Qi Wen Teo, Jingshu Zhang, Kevin Leandro, Denzel Eggermont, Delphine De Sutter, Katie Boucher, Tino Hochepied, Nele Festjens, Nico Callewaert, Xavier Saelens, Bart Dermaut, Klaus-Peter Knobeloch, Antje Beling, Sumana Sanyal, Lilliana Radoshevich, Sven Eyckerman, Francis Impens

Nat Commun. 2021; 12: 5772. Published online 2021 Oct 1. doi: 10.1038/s41467-021-26061-w

PMCID:: PMC8486878

Abstract Article PDF–7.6M

Select item 356134314.

VCP Phosphorylation-Dependent Interaction Partners Prevent Apoptosis in Helicobacter pylori-Infected Gastric Epithelial Cells

Cheng-Chou Yu, Jyh-Chin Yang, Yen-Ching Chang, Jiing-Guang Chuang, Chung-Wu Lin, Ming-Shiang Wu, Lu-Ping Chow

PLoS One. 2013; 8(1): e55724. Published online 2013 Jan 31. doi: 10.1371/journal.pone.0055724

PMCID:: PMC3561343

Abstract Article PDF–1.9M

Select item 629825415.

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert

Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289

PMCID:: PMC6298254

Abstract Article PDF–1.4M

Select item 410454416.

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways

Mikko Taipale, George Tucker, Jian Peng, Irina Krykbaeva, Zhen-Yuan Lin, Brett Larsen, Hyungwon Choi, Bonnie Berger, Anne-Claude Gingras, Susan Lindquist

Cell. Author manuscript; available in PMC 2015 Jul 17.

Published in final edited form as: Cell. 2014 Jul 17; 158(2): 434–448. doi: 10.1016/j.cell.2014.05.039

PMCID:: PMC4104544

Abstract Article PDF–3.2M

Select item 884216517.

CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system

Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar

Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629

PMCID:: PMC8842165

Abstract Article PDF–3.0M

Select item 1110948318.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 1007290619.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 742732720.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

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