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Items: 1 to 20 of 56

1.
The SCFFBXO3 ubiquitin E3 ligase regulates inflammation in atherosclerosis
Divay Chandra, James Londino, Shaun Alexander, Joseph S. Bednash, Yingze Zhang, Robert M. Friedlander, Grant Daskivich, Diane L. Carlisle, William R. Lariviere, Ana Carolina Igami Nakassa, Mark Ross, Claudette Croix, St., Toru Nyunoya, Frank Sciurba, Bill Chen, Rama K. Mallampalli
J Mol Cell Cardiol. Author manuscript; available in PMC 2020 Aug 13.
Published in final edited form as: J Mol Cell Cardiol. 2019 Jan; 126: 50–59. Published online 2018 Nov 16. doi: 10.1016/j.yjmcc.2018.11.006
PMCID:
PMC7425077
AbstractArticlePDF–1.4M
2.
The SCFFBXO46 ubiquitin ligase complex mediates degradation of the tumor suppressor FBXO31 and thereby prevents premature cellular senescence
Srinadh Choppara, Sankaran Ganga, Rajeshkumar Manne, Parul Dutta, Shailza Singh, Manas Kumar Santra
J Biol Chem. 2018 Oct 19; 293(42): 16291–16306. Published online 2018 Aug 31. doi: 10.1074/jbc.RA118.005354
PMCID:
PMC6200945
AbstractArticlePDF–3.8M
3.
Crystal structure and interaction studies of the human FBxo3 ApaG domain
Troy C. Krzysiak, Bill B. Chen, Travis Lear, Rama K. Mallampalli, Angela M. Gronenborn
FEBS J. Author manuscript; available in PMC 2016 Oct 14.
Published in final edited form as: FEBS J. 2016 Jun; 283(11): 2091–2101. Published online 2016 Apr 22. doi: 10.1111/febs.13721
PMCID:
PMC5065005
AbstractArticlePDF–1.0M
4.
Virulence Factor NSs of Rift Valley Fever Virus Recruits the F-Box Protein FBXO3 To Degrade Subunit p62 of General Transcription Factor TFIIH
Markus Kainulainen, Matthias Habjan, Philipp Hubel, Laura Busch, Simone Lau, Jacques Colinge, Giulio Superti-Furga, Andreas Pichlmair, Friedemann Weber
J Virol. 2014 Mar; 88(6): 3464–3473. doi: 10.1128/JVI.02914-13
PMCID:
PMC3957945
AbstractArticlePDF–2.8M
5.
A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation
Bill B. Chen, Tiffany A. Coon, Jennifer R. Glasser, Bryan J. McVerry, Jing Zhao, Yutong Zhao, Chunbin Zou, Bryon Ellis, Frank C. Sciurba, Yingze Zhang, Rama K. Mallampalli
Nat Immunol. Author manuscript; available in PMC 2013 Nov 1.
Published in final edited form as: Nat Immunol. 2013 May; 14(5): 470–479. Published online 2013 Mar 31. doi: 10.1038/ni.2565
PMCID:
PMC3631463
AbstractArticlePDF–2.3M
6.
Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCFFBXL2 E3 Ligase
SeungHye Han, Travis B. Lear, Jacob A. Jerome, Shristi Rajbhandari, Courtney A. Snavely, Dexter L. Gulick, Kevin F. Gibson, Chunbin Zou, Bill B. Chen, Rama K. Mallampalli
J Biol Chem. 2015 Jul 17; 290(29): 18124–18133. Published online 2015 Jun 2. doi: 10.1074/jbc.M115.645549
PMCID:
PMC4505057
AbstractArticlePDF–1.4M
7.
FBXO3 stabilizes USP4 and Twist1 to promote PI3K-mediated breast cancer metastasis
Jing Xu, Rongtian Guo, Nasi Wen, Luping Li, Yong Yi, Jingzhen Chen, Zongyu He, Jian Yang, Zhi-Xiong Jim Xiao, Mengmeng Niu
PLoS Biol. 2023 Dec; 21(12): e3002446. Published online 2023 Dec 22. doi: 10.1371/journal.pbio.3002446
PMCID:
PMC10745200
AbstractArticlePDF–3.2M
8.
Extracellular matrix stiffness regulates degradation of MST2 via SCF βTrCP
Ana Paula Zen Petisco Fiore, Ana Maria Rodrigues, Helder Veras Ribeiro-Filho, Antonio Carlos Manucci, Pedro de Freitas Ribeiro, Mayara Carolinne Silva Botelho, Christine Vogel, Paulo Sergio Lopes-de-Oliveira, Michele Pagano, Alexandre Bruni-Cardoso
Biochim Biophys Acta Gen Subj. Author manuscript; available in PMC 2023 Dec 1.
Published in final edited form as: Biochim Biophys Acta Gen Subj. 2022 Dec; 1866(12): 130238. Published online 2022 Aug 28. doi: 10.1016/j.bbagen.2022.130238
PMCID:
PMC9926743
AbstractArticlePDF–1.0M
9.
An Amyotrophic Lateral Sclerosis-Associated Mutant of C21ORF2 Is Stabilized by NEK1-Mediated Hyperphosphorylation and the Inability to Bind FBXO3
Yasuaki Watanabe, Tadashi Nakagawa, Tetsuya Akiyama, Makiko Nakagawa, Naoki Suzuki, Hitoshi Warita, Masashi Aoki, Keiko Nakayama
iScience. 2020 Sep 25; 23(9): 101491. Published online 2020 Aug 21. doi: 10.1016/j.isci.2020.101491
PMCID:
PMC7481237
AbstractArticlePDF–4.2M
10.
PML Activates Transcription by Protecting HIPK2 and p300 from SCFFbx3-Mediated Degradation
Yutaka Shima, Takito Shima, Tomoki Chiba, Tatsuro Irimura, Pier Paolo Pandolfi, Issay Kitabayashi
Mol Cell Biol. 2008 Dec; 28(23): 7126–7138. Published online 2008 Sep 22. doi: 10.1128/MCB.00897-08
PMCID:
PMC2593379
AbstractArticlePDF–1.9M
11.
FBXL2 counteracts Grp94 to destabilize EGFR and inhibit EGFR-driven NSCLC growth
Mengmeng Niu, Jing Xu, Yang Liu, Yuhuang Li, Tao He, Liangping Ding, Yajun He, Yong Yi, Fengtian Li, Rongtian Guo, Ya Gao, Rui Li, Luping Li, Mengyuan Fu, Qingyong Hu, Yangkun Luo, Chunyan Zhang, Kewei Qin, Jianqiao Yi, Shuhan Yu, Jian Yang, Hu Chen, Liang Wang, Zhonghan Li, Biao Dong, Shiqian Qi, Liang Ouyang, Yujun Zhang, Yang Cao, Zhi-Xiong Jim Xiao
Nat Commun. 2021; 12: 5919. Published online 2021 Oct 11. doi: 10.1038/s41467-021-26222-x
PMCID:
PMC8505509
AbstractArticlePDF–7.1M
12.
Cyclin F controls cell cycle transcriptional outputs by directing the degradation of the three activator E2Fs
Linda Clijsters, Claire Hoencamp, Jorg J. A. Calis, Antonio Marzio, Shanna M. Handgraaf, Maria C. Cuitino, Brad R. Rosenberg, Gustavo Leone, Michele Pagano
Mol Cell. Author manuscript; available in PMC 2020 Jun 20.
Published in final edited form as: Mol Cell. 2019 Jun 20; 74(6): 1264–1277.e7. Published online 2019 May 23. doi: 10.1016/j.molcel.2019.04.010
PMCID:
PMC6588466
AbstractArticlePDF–2.7M
13.
FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator)
Wei Shao, Kristina Zumer, Koh Fujinaga, B. Matija Peterlin
J Biol Chem. 2016 Aug 19; 291(34): 17953–17963. Published online 2016 Jun 30. doi: 10.1074/jbc.M116.724401
PMCID:
PMC5016183
AbstractArticlePDF–1.0M
14.
Nrf2 activation promotes lung cancer metastasis by inhibiting the degradation of Bach1
Luca Lignitto, Sarah E. LeBoeuf, Harrison Homer, Shaowen Jiang, Manor Askenazi, Triantafyllia R. Karakousi, Harvey I. Pass, Arjun J. Bhutkar, Aristotelis Tsirigos, Beatrix Ueberheide, Volkan I. Sayin, Thales Papagiannakopoulos, Michele Pagano
Cell. Author manuscript; available in PMC 2020 Jul 11.
Published in final edited form as: Cell. 2019 Jul 11; 178(2): 316–329.e18. Published online 2019 Jun 27. doi: 10.1016/j.cell.2019.06.003
PMCID:
PMC6625921
AbstractArticlePDF–3.1M
15.
The Cyclin F-Ribonucleotide Reductase M2 axis controls genome integrity and DNA repair
Vincenzo D’Angiolella, Valerio Donato, Frances M. Forrester, Yeon-Tae Jeong, Claudia Pellacani, Yasusei Kudo, Anita Saraf, Laurence Florens, Michael P. Washburn, Michele Pagano
Cell. Author manuscript; available in PMC 2013 Apr 4.
Published in final edited form as: Cell. 2012 May 25; 149(5): 1023–1034. doi: 10.1016/j.cell.2012.03.043
PMCID:
PMC3616325
AbstractArticlePDF–2.3M
16.
CUL7: A DOC domain-containing cullin selectively binds Skp1⋅Fbx29 to form an SCF-like complex
Dora C. Dias, Georgia Dolios, Rong Wang, Zhen-Qiang Pan
Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16601–16606. Published online 2002 Dec 12. doi: 10.1073/pnas.252646399
PMCID:
PMC139190
AbstractArticlePDF–387K
17.
Tumor-associated antigen Prame targets tumor suppressor p14/ARF for degradation as the  receptor protein of CRL2Prame complex
Wenjuan Zhang, Lihui Li, Lili Cai, Yupei Liang, Junfeng Xu, Yue Liu, Lisha Zhou, Chen Ding, Yanmei Zhang, Hu Zhao, Jun Qin, Zhimin Shao, Wenyi Wei, Lijun Jia
Cell Death Differ. 2021 Jun; 28(6): 1926–1940. Published online 2021 Jan 27. doi: 10.1038/s41418-020-00724-5
PMCID:
PMC8184998
AbstractArticlePDF–4.0M
18.
Genetics of coronary artery calcification among African Americans, a meta-analysis
Mary K Wojczynski, Mingyao Li, Lawrence F Bielak, Kathleen F Kerr, Alex P Reiner, Nathan D Wong, Lisa R Yanek, Liming Qu, Charles C White, Leslie A Lange, Jane F Ferguson, Jing He, Taylor Young, Thomas H Mosley, Jennifer A Smith, Brian G Kral, Xiuqing Guo, Quenna Wong, Santhi K Ganesh, Susan R Heckbert, Michael E Griswold, Daniel H O’Leary, Matthew Budoff, J Jeffrey Carr, Herman A Taylor,, Jr., David A Bluemke, Serkalem Demissie, Shih-Jen Hwang, Dina N Paltoo, Joseph F Polak, Bruce M Psaty, Diane M Becker, Michael A Province, Wendy S Post, Christopher J O’Donnell, James G Wilson, Tamara B Harris, Maryam Kavousi, L Adrienne Cupples, Jerome I Rotter, Myriam Fornage, Lewis C Becker, Patricia A Peyser, Ingrid B Borecki, Muredach P Reilly
BMC Med Genet. 2013; 14: 75. Published online 2013 Jul 19. doi: 10.1186/1471-2350-14-75
PMCID:
PMC3733595
AbstractArticlePDF–884K
19.
Systemwide disassembly and assembly of SCF ubiquitin ligase complexes
Kheewoong Baek, Daniel C. Scott, Lukas T. Henneberg, Moeko T. King, Matthias Mann, Brenda A. Schulman
Cell. 2023 Apr 27; 186(9): 1895–1911.e21. doi: 10.1016/j.cell.2023.02.035
Correction in:
Cell. 2023 May 25; 186(11): 2492.
PMCID:
PMC10156175
AbstractArticle
20.
Composition and regulation of the cellular repertoire of SCF ubiquitin ligases
Justin M. Reitsma, Xing Liu, Kurt M. Reichermeier, Annie Moradian, Michael J. Sweredoski, Sonja Hess, Raymond J. Deshaies
Cell. Author manuscript; available in PMC 2018 Nov 30.
Published in final edited form as: Cell. 2017 Nov 30; 171(6): 1326–1339.e14. Published online 2017 Nov 2. doi: 10.1016/j.cell.2017.10.016
PMCID:
PMC5711595
AbstractArticlePDF–2.4M

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