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Items: 1 to 20 of 59

1.
Deubiquitinating Enzyme USP21 Inhibits HIV-1 Replication by Downregulating Tat Expression
Wenying Gao, Guangquan Li, Simin Zhao, Hong Wang, Chen Huan, Baisong Zheng, Chunlai Jiang, Wenyan Zhang
J Virol. 2021 Jul; 95(13): e00460-21. Prepublished online 2021 Apr 7. Published online 2021 Jun 10. doi: 10.1128/JVI.00460-21
PMCID:
PMC8316079
AbstractArticlePDF–2.6M
2.
Proteome-wide search for functional motifs altered in tumors: Prediction of nuclear export signals inactivated by cancer-related mutations
Gorka Prieto, Asier Fullaondo, Jose A. Rodríguez
Sci Rep. 2016; 6: 25869. Published online 2016 May 12. doi: 10.1038/srep25869
PMCID:
PMC4865848
AbstractArticlePDF–1.2M
3.
USP21 promotes self-renewal and tumorigenicity of mesenchymal glioblastoma stem cells by deubiquitinating and stabilizing FOXD1
Qixiang Zhang, Zhengxin Chen, Qikai Tang, Zhangjie Wang, Jiacheng Lu, Yongping You, Huibo Wang
Cell Death Dis. 2022 Aug; 13(8): 712. Published online 2022 Aug 16. doi: 10.1038/s41419-022-05163-3
PMCID:
PMC9381540
AbstractArticlePDF–9.6M
4.
RBM47/SNHG5/FOXO3 axis activates autophagy and inhibits cell proliferation in papillary thyroid carcinoma
Yuan Qin, Wei Sun, Zhihong Wang, Wenwu Dong, Liang He, Ting Zhang, Chengzhou Lv, Hao Zhang
Cell Death Dis. 2022 Mar; 13(3): 270. Published online 2022 Mar 25. doi: 10.1038/s41419-022-04728-6
PMCID:
PMC8956740
AbstractArticlePDF–6.1M
5.
Ablation of USP21 in skeletal muscle promotes oxidative fibre phenotype, inhibiting obesity and type 2 diabetes
Ayoung Kim, Ja Hyun Koo, Xing Jin, Wondong Kim, Shi‐Young Park, Sunghyouk Park, Eugene P. Rhee, Cheol Soo Choi, Sang Geon Kim
J Cachexia Sarcopenia Muscle. 2021 Dec; 12(6): 1669–1689. Published online 2021 Sep 15. doi: 10.1002/jcsm.12777
PMCID:
PMC8718070
AbstractArticlePDF–10M
6.
De-Ubiquitinating Enzymes USP21 Regulate MAPK1 Expression by Binding to Transcription Factor GATA3 to Regulate Tumor Growth and Cell Stemness of Gastric Cancer
Qingqu Guo, Dike Shi, Lele Lin, Hongbo Li, Yunhai Wei, Baozhong Li, Dan Wu
Front Cell Dev Biol. 2021; 9: 641981. Published online 2021 Mar 15. doi: 10.3389/fcell.2021.641981
PMCID:
PMC8005622
AbstractArticlePDF–4.0M
7.
USP21 promotes cell proliferation by maintaining the EZH2 level in diffuse large B‐cell lymphoma
Huixian Ma, Xiangrui Luo, Peng Zhou, Na He, Jun Zhou, Min Liu, Wei Xie
J Clin Lab Anal. 2021 Mar; 35(3): e23693. Published online 2021 Jan 2. doi: 10.1002/jcla.23693
PMCID:
PMC7957995
AbstractArticlePDF–898K
8.
Distinct regulatory ribosomal ubiquitylation events are reversible and hierarchically organized
Danielle M Garshott, Elayanambi Sundaramoorthy, Marilyn Leonard, Eric J Bennett
eLife. 2020; 9: e54023. Published online 2020 Feb 3. doi: 10.7554/eLife.54023
PMCID:
PMC7064338
AbstractArticlePDF–4.5M
9.
USP21 deubiquitinase promotes pancreas cancer cell stemness via Wnt pathway activation
Pingping Hou, Xingdi Ma, Qiang Zhang, Chang-Jiun Wu, Wenting Liao, Jun Li, Huamin Wang, Jun Zhao, Xin Zhou, Carolyn Guan, Jeffery Ackroyd, Shan Jiang, Jianhua Zhang, Denise J. Spring, Y. Alan Wang, Ronald A. DePinho
Genes Dev. 2019 Oct 1; 33(19-20): 1361–1366. doi: 10.1101/gad.326314.119
PMCID:
PMC6771391
AbstractArticlePDF–4.0M
10.
FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer
Anthony Arceci, Thomas Bonacci, Xianxi Wang, Kyle Stewart, Jeffrey S. Damrauer, Katherine A. Hoadley, Michael J. Emanuele
Cell Rep. Author manuscript; available in PMC 2019 Mar 20.
Published in final edited form as: Cell Rep. 2019 Mar 12; 26(11): 3076–3086.e6. doi: 10.1016/j.celrep.2019.02.054
PMCID:
PMC6425951
AbstractArticlePDF–1.5M
11.
The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth
Wenjuan Li, Kaisa Cui, Edward V Prochownik, Youjun Li
Cell Death Dis. 2018 May; 9(5): 482. Published online 2018 Apr 30. doi: 10.1038/s41419-018-0523-z
PMCID:
PMC5924753
AbstractArticlePDF–1.3M
12.
Ubiquitin specific peptidase 21 regulates interleukin-8 expression, stem-cell like property of human renal cell carcinoma
Liang Peng, Yi Hu, Demeng Chen, Shunchang Jiao, Shengkun Sun
Oncotarget. 2016 Jul 5; 7(27): 42007–42016. Published online 2016 May 31. doi: 10.18632/oncotarget.9751
PMCID:
PMC5173112
AbstractArticlePDF–8.7M
13.
Deubiquitination and stabilization of IL-33 by USP21
Lianqin Tao, Chen Chen, Huihui Song, Miranda Piccioni, Guochao Shi, Bin Li
Int J Clin Exp Pathol. 2014; 7(8): 4930–4937. Published online 2014 Jul 15.
PMCID:
PMC4152054
AbstractArticlePDF–620K
14.
The USP21/YY1/SNHG16 axis contributes to tumor proliferation, migration, and invasion of non-small-cell lung cancer
Pei Xu, Haibo Xiao, Qi Yang, Rui Hu, Lianyong Jiang, Rui Bi, Xueyan Jiang, Lei Wang, Ju Mei, Fangbao Ding, Jianbing Huang
Exp Mol Med. 2020 Jan; 52(1): 41–55. Published online 2020 Jan 20. doi: 10.1038/s12276-019-0356-6
PMCID:
PMC7000404
AbstractArticlePDF–2.9M
15.
USP21 modulates Goosecoid function through deubiquitination
Fuwei Liu, Qian Fu, Yunpeng Li, Kai Zhang, Mingyue Tang, Wei Jiang, Bin Bo, Yajun Cui, Liang Kong
Biosci Rep. 2019 Jul 31; 39(7): BSR20182148. Prepublished online 2019 Jun 28. Published online 2019 Jul 10. doi: 10.1042/BSR20182148
PMCID:
PMC6620385
AbstractArticlePDF–1.4M
16.
Saturation scanning of ubiquitin variants reveals a common hot spot for binding to USP2 and USP21
Isabel Leung, Ayelet Dekel, Julia M. Shifman, Sachdev S. Sidhu
Proc Natl Acad Sci U S A. 2016 Aug 2; 113(31): 8705–8710. Published online 2016 Jul 19. doi: 10.1073/pnas.1524648113
PMCID:
PMC4978272
AbstractArticlePDF–1.7M
17.
Identification of the E3 Deubiquitinase Ubiquitin-specific Peptidase 21 (USP21) as a Positive Regulator of the Transcription Factor GATA3
Jing Zhang, Chen Chen, Xiaoxia Hou, Yayi Gao, Fang Lin, Jing Yang, Zhimei Gao, Lina Pan, Lianqin Tao, Chijun Wen, Zhengju Yao, Andy Tsun, Guochao Shi, Bin Li
J Biol Chem. 2013 Mar 29; 288(13): 9373–9382. Published online 2013 Feb 10. doi: 10.1074/jbc.M112.374744
PMCID:
PMC3611007
AbstractArticlePDF–1.7M
18.
Dual role of a GTPase conformational switch for membrane fusion by mitofusin ubiquitylation
Ramona Schuster, Vincent Anton, Tânia Simões, Selver Altin, Fabian den Brave, Thomas Hermanns, Manuela Hospenthal, David Komander, Gunnar Dittmar, R Jürgen Dohmen, Mafalda Escobar-Henriques
Life Sci Alliance. 2020 Jan; 3(1): e201900476. Published online 2019 Dec 19. doi: 10.26508/lsa.201900476
PMCID:
PMC6925385
AbstractArticlePDF–2.0M
19.
USP21 deubiquitylates Nanog to regulate protein stability and stem cell pluripotency
Xingyu Liu, Yuying Yao, Huiguo Ding, Chuanchun Han, Yuhan Chen, Yuan Zhang, Chanjuan Wang, Xin Zhang, Yiling Zhang, Yun Zhai, Ping Wang, Wenyi Wei, Jing Zhang, Lingqiang Zhang
Signal Transduct Target Ther. 2016; 1: 16024. Published online 2016 Nov 4. doi: 10.1038/sigtrans.2016.24
Correction in:
Signal Transduct Target Ther. 2017; 2: 16046.
PMCID:
PMC5661642
AbstractArticlePDF–1.5M
20.
Ubiquitin-specific protease 21 stabilizes BRCA2 to control DNA repair and tumor growth
Jinping Liu, Alex Kruswick, Hien Dang, Andy D. Tran, So Mee Kwon, Xin Wei Wang, Philipp Oberdoerffer
Nat Commun. 2017; 8: 137. Published online 2017 Jul 26. doi: 10.1038/s41467-017-00206-2
PMCID:
PMC5526993
AbstractArticlePDF–1.6M

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