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Select item 104847411.

Human TRMT2A methylates tRNA and contributes to translation fidelity

Monika Witzenberger, Sandra Burczyk, David Settele, Wieland Mayer, Luisa M Welp, Matthias Heiss, Mirko Wagner, Thomas Monecke, Robert Janowski, Thomas Carell, Henning Urlaub, Stefanie M Hauck, Aaron Voigt, Dierk Niessing

Nucleic Acids Res. 2023 Sep 8; 51(16): 8691–8710. Published online 2023 Jul 3. doi: 10.1093/nar/gkad565

PMCID:: PMC10484741

Abstract Article PDF–3.8M

Select item 81483902.

Chemical tagging for sensitive determination of uridine modifications in RNA

Qing-Yun Cheng, Jun Xiong, Cheng-Jie Ma, Yi Dai, Jiang-Hui Ding, Fei-Long Liu, Bi-Feng Yuan, Yu-Qi Feng

Chem Sci. 2020 Feb 21; 11(7): 1878–1891. Published online 2020 Jan 8. doi: 10.1039/c9sc05094a

PMCID:: PMC8148390

Abstract Article PDF–1.8M

Select item 80019833.

m⁵U54 tRNA Hypomodification by Lack of TRMT2A Drives the Generation of tRNA-Derived Small RNAs

Marisa Pereira, Diana R. Ribeiro, Miguel M. Pinheiro, Margarida Ferreira, Stefanie Kellner, Ana R. Soares

Int J Mol Sci. 2021 Mar; 22(6): 2941. Published online 2021 Mar 14. doi: 10.3390/ijms22062941

PMCID:: PMC8001983

Abstract Article PDF–2.9M

Select item 68211914.

FICC-Seq: a method for enzyme-specified profiling of methyl-5-uridine in cellular RNA

Jean-Michel Carter, Warren Emmett, Igor Rdl Mozos, Annika Kotter, Mark Helm, Jernej Ule, Shobbir Hussain

Nucleic Acids Res. 2019 Nov 4; 47(19): e113. Published online 2019 Jul 30. doi: 10.1093/nar/gkz658

PMCID:: PMC6821191

Abstract Article PDF–3.7M

Select item 28597535.

The expression of TRMT2A, a novel cell cycle regulated protein, identifies a subset of breast cancer patients with HER2 over-expression that are at an increased risk of recurrence

David G Hicks, Bagi R Janarthanan, Ramya Vardarajan, Swati A Kulkarni, Thaer Khoury, Daniel Dim, G Thomas Budd, Brian J Yoder, Raymond Tubbs, Marshall T Schreeder, Noel C Estopinal, Rodney A Beck, Yanling Wang, Brian Z Ring, Robert S Seitz, Douglas T Ross

BMC Cancer. 2010; 10: 108. Published online 2010 Mar 22. doi: 10.1186/1471-2407-10-108

PMCID:: PMC2859753

Abstract Article PDF–641K

Select item 85510196.

Activity-based RNA modifying enzyme probing reveals DUS3L-mediated dihydrouridylation

Wei Dai, Ang Li, Nathan J. Yu, Thao Nguyen, Robert W. Leach, Martin Wühr, Ralph E. Kleiner

Nat Chem Biol. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nat Chem Biol. 2021 Nov; 17(11): 1178–1187. Published online 2021 Sep 23. doi: 10.1038/s41589-021-00874-8

PMCID:: PMC8551019

Abstract Article PDF–1.6M

Select item 82547597.

HectD1 Controls Hematopoietic Stem Cell Regeneration by Coordinating Ribosome Assembly and Protein Synthesis

Kaosheng Lv, Chujie Gong, Charles Antony, Xu Han, Jian-Gang Ren, Ryan Donaghy, Ying Cheng, Simone Pellegrino, Alan J. Warren, Vikram R. Paralkar, Wei Tong

Cell Stem Cell. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Cell Stem Cell. 2021 Jul 1; 28(7): 1275–1290.e9. Published online 2021 Mar 11. doi: 10.1016/j.stem.2021.02.008

PMCID:: PMC8254759

Abstract Article PDF–2.8M

Select item 43244398.

Proteomic Analysis and Identification of Cellular Interactors of the Giant Ubiquitin Ligase HERC2

Jeffrey T. Galligan, Gustavo Martinez-Noël, Verena Arndt, Sebastian Hayes, Thomas W. Chittenden, J. Wade Harper, Peter M. Howley

J Proteome Res. 2015 Feb 6; 14(2): 953–966. Published online 2014 Dec 4. doi: 10.1021/pr501005v

PMCID:: PMC4324439

Abstract Article PDF–7.5M

Select item 34203409.

MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity

Oliver Stehling, Ajay A. Vashisht, Judita Mascarenhas, Zophonias O. Jonsson, Tanu Sharma, Daili J.A. Netz, Antonio J. Pierik, James A. Wohlschlegel, Roland Lill

Science. Author manuscript; available in PMC 2013 Jan 13.

Published in final edited form as: Science. 2012 Jul 13; 337(6091): 195–199. Published online 2012 Jun 7. doi: 10.1126/science.1219723

PMCID:: PMC3420340

Abstract Article PDF–1.8M

Select item 593507410.

Mapping the mammalian ribosome quality control complex interactome using proximity labeling approaches

Nathan Zuzow, Arit Ghosh, Marilyn Leonard, Jeffrey Liao, Bing Yang, Eric J. Bennett

Mol Biol Cell. 2018 May 15; 29(10): 1258–1269. doi: 10.1091/mbc.E17-12-0714

PMCID:: PMC5935074

Abstract Article PDF–5.9M

Select item 818479611.

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells

Nadia Habel, Najla El-Hachem, Frédéric Soysouvanh, Hanene Hadhiri-Bzioueche, Serena Giuliano, Sophie Nguyen, Pavel Horák, Anne-Sophie Gay, Delphine Debayle, Nicolas Nottet, Guillaume Béranger, Brigitte Bressac-de Paillerets, Corine Bertolotto, Robert Ballotti

Cell Death Differ. 2021 Jun; 28(6): 1837–1848. Published online 2021 Jan 18. doi: 10.1038/s41418-020-00710-x

PMCID:: PMC8184796

Abstract Article PDF–2.4M

Select item 386161612.

The HECT Type Ubiquitin Ligase NEDL2 Is Degraded by Anaphase-promoting Complex/Cyclosome (APC/C)-Cdh1, and Its Tight Regulation Maintains the Metaphase to Anaphase Transition

Li Lu, Shaohua Hu, Rongfei Wei, Xiao Qiu, Kefeng Lu, Yesheng Fu, Hongchang Li, Guichun Xing, Dong Li, Ruiyun Peng, Fuchu He, Lingqiang Zhang

J Biol Chem. 2013 Dec 13; 288(50): 35637–35650. Published online 2013 Oct 25. doi: 10.1074/jbc.M113.472076

PMCID:: PMC3861616

Abstract Article PDF–4.4M

Select item 54560413.

A genome annotation-driven approach to cloning the human ORFeome

John E Collins, Charmain L Wright, Carol A Edwards, Matthew P Davis, James A Grinham, Charlotte G Cole, Melanie E Goward, Begoña Aguado, Meera Mallya, Younes Mokrab, Elizabeth J Huckle, David M Beare, Ian Dunham

Genome Biol. 2004; 5(10): R84. Published online 2004 Sep 30. doi: 10.1186/gb-2004-5-10-r84

PMCID:: PMC545604

Abstract Article PDF–762K

Select item 325365814.

Mapping a Dynamic Innate Immunity Protein Interaction Network Regulating Type I Interferon Production

Shitao Li, Lingyan Wang, Michael Berman, Young-Yun Kong, Martin E. Dorf

Immunity. Author manuscript; available in PMC 2012 Sep 23.

Published in final edited form as: Immunity. 2011 Sep 23; 35(3): 426–440. Published online 2011 Sep 8. doi: 10.1016/j.immuni.2011.06.014

Correction in:: volume 35 on page 647

PMCID:: PMC3253658

Abstract Article PDF–4.2M

Select item 737304815.

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis

Jingjiao Li, Mingquan Guo, Xiaoxu Tian, Xin Wang, Xing Yang, Ping Wu, Chengrong Liu, Zixuan Xiao, Yafei Qu, Yue Yin, Chunxia Wang, Yucai Zhang, Zhaoqin Zhu, Zhenshan Liu, Chao Peng, Tongyu Zhu, Qiming Liang

Med (N Y) 2021 Jan 15; 2(1): 99–112.e7. Published online 2020 Jul 21. doi: 10.1016/j.medj.2020.07.002

PMCID:: PMC7373048

Abstract Article PDF–3.8M

Select item 408310616.

Proteomic Analysis of the Epidermal Growth Factor Receptor (EGFR) Interactome and Post-translational Modifications Associated with Receptor Endocytosis in Response to EGF and Stress

Jiefei Tong, Paul Taylor, Michael F. Moran

Mol Cell Proteomics. 2014 Jul; 13(7): 1644–1658. Published online 2014 May 5. doi: 10.1074/mcp.M114.038596

PMCID:: PMC4083106

Abstract Article PDF–2.6M

Select item 402487817.

TRIM65 regulates microRNA activity by ubiquitination of TNRC6

Shitao Li, Lingyan Wang, Bishi Fu, Michael A. Berman, Alos Diallo, Martin E. Dorf

Proc Natl Acad Sci U S A. 2014 May 13; 111(19): 6970–6975. Published online 2014 Apr 28. doi: 10.1073/pnas.1322545111

PMCID:: PMC4024878

Abstract Article PDF–1.1M

Select item 760600818.

BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A

Chun‐guo Mao, Sha‐sha Jiang, Cheng Shen, Tan Long, Hua Jin, Qun‐You Tan, Bo Deng

Thorac Cancer. 2020 Nov; 11(11): 3326–3336. Published online 2020 Oct 1. doi: 10.1111/1759-7714.13676

PMCID:: PMC7606008

Abstract Article PDF–2.5M

Select item 810809319.

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary

Cell. Author manuscript; available in PMC 2021 May 10.

Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050

PMCID:: PMC8108093

Abstract Article PDF–3.5M

Select item 889438020.

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing

Alexandra Bergfort, Marco Preußner, Benno Kuropka, İbrahim Avşar Ilik, Tarek Hilal, Gert Weber, Christian Freund, Tuğçe Aktaş, Florian Heyd, Markus C. Wahl

Nat Commun. 2022; 13: 1132. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28754-2