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Select item 45109821.

MTBP inhibits migration and metastasis of hepatocellular carcinoma

Qian Bi, Atul Ranjan, Rui Fan, Neeraj Agarwal, Danny R. Welch, Steven A. Weinman, Jie Ding, Tomoo Iwakuma

Clin Exp Metastasis. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: Clin Exp Metastasis. 2015 Apr; 32(4): 301–311. Published online 2015 Mar 11. doi: 10.1007/s10585-015-9706-5

PMCID:: PMC4510982

Abstract Article PDF–1.0M

Select item 41635102.

MTBP is Over-expressed in Triple Negative Breast Cancer and Contributes to its Growth and Survival

Brian C. Grieb, Xi Chen, Christine M. Eischen

Mol Cancer Res. Author manuscript; available in PMC 2015 Sep 1.

Published in final edited form as: Mol Cancer Res. 2014 Sep; 12(9): 1216–1224. Published online 2014 May 27. doi: 10.1158/1541-7786.MCR-14-0069

PMCID:: PMC4163510

Abstract Article PDF–975K

Select item 75236323.

Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication

Akiko Kumagai, William G. Dunphy

Cell Rep. Author manuscript; available in PMC 2020 Sep 29.

Published in final edited form as: Cell Rep. 2020 Sep 22; 32(12): 108178. doi: 10.1016/j.celrep.2020.108178

PMCID:: PMC7523632

Abstract Article PDF–2.5M

Select item 40797484.

Oncogenic protein MTBP interacts with MYC to promote tumorigenesis

Brian C. Grieb, Mark W. Gramling, Maria Pia Arrate, Xi Chen, Stephen L. Beauparlant, Dale S. Haines, Hua Xiao, Christine M. Eischen

Cancer Res. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: Cancer Res. 2014 Jul 1; 74(13): 3591–3602. Published online 2014 May 1. doi: 10.1158/0008-5472.CAN-13-2149

PMCID:: PMC4079748

Abstract Article PDF–757K

Select item 37423335.

MTBP suppresses cell migration and filopodia formation by inhibiting ACTN4

Neeraj Agarwal, Amit S. Adhikari, Swathi V. Iyer, Kevon Hekmatdoost, Danny R. Welch, Tomoo Iwakuma

Oncogene. Author manuscript; available in PMC 2013 Aug 13.

Published in final edited form as: Oncogene. 2013 Jan 24; 32(4): 462–470. Published online 2012 Feb 27. doi: 10.1038/onc.2012.69

PMCID:: PMC3742333

Abstract Article PDF–1.2M

Select item 67353646.

MTBP regulates cell survival and therapeutic sensitivity in TP53 wildtype glioblastomas

Yifu Song, Li Zhang, Yang Jiang, Tianhao Hu, Di Zhang, Qiao Qiao, Run Wang, Minghao Wang, Sheng Han

Theranostics. 2019; 9(20): 6019–6030. Published online 2019 Aug 14. doi: 10.7150/thno.35747

PMCID:: PMC6735364

Abstract Article PDF–2.7M

Select item 5434057.

Regulation of p53 and MDM2 Activity by MTBP

Mark Brady, Nikolina Vlatković, Mark T. Boyd

Mol Cell Biol. 2005 Jan; 25(2): 545–553. doi: 10.1128/MCB.25.2.545-553.2005

PMCID:: PMC543405

Abstract Article PDF–392K

Select item 28806628.

A deficiency in Mdm2 binding protein (MTBP) inhibits Myc-induced B cell proliferation and lymphomagenesis

Jessica Odvody, Tiffaney Vincent, Maria Pia Arrate, Brian Grieb, Shuo Wang, Judit Garriga, Guillermina Lozano, Tomoo Iwakuma, Dale S. Haines, Christine M. Eischen

Oncogene. Author manuscript; available in PMC 2010 Dec 3.

Published in final edited form as: Oncogene. 2010 Jun 3; 29(22): 3287–3296. Published online 2010 Mar 22. doi: 10.1038/onc.2010.82

PMCID:: PMC2880662

Abstract Article PDF–3.9M

Select item 41963779.

Epidemiological and Genome-Wide Association Study of Gastritis or Gastric Ulcer in Korean Populations

Sumin Oh, Sejong Oh

Genomics Inform. 2014 Sep; 12(3): 127–133. Published online 2014 Sep 30. doi: 10.5808/GI.2014.12.3.127

PMCID:: PMC4196377

Abstract Article PDF–533K

Select item 313195010.

MTBP plays a crucial role in mitotic progression and chromosome segregation

N Agarwal, Y Tochigi, A S Adhikari, S Cui, Y Cui, T Iwakuma

Cell Death Differ. 2011 Jul; 18(7): 1208–1219. Published online 2011 Jan 28. doi: 10.1038/cdd.2010.189

PMCID:: PMC3131950

Abstract Article PDF–1011K

Select item 637714811.

The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7

Kerstin Köhler, Luis Sanchez-Pulido, Verena Höfer, Anika Marko, Chris P. Ponting, Ambrosius P. Snijders, Regina Feederle, Aloys Schepers, Dominik Boos

PLoS Biol. 2019 Jan; 17(1): e2006767. Published online 2019 Jan 29. doi: 10.1371/journal.pbio.2006767

PMCID:: PMC6377148

Abstract Article PDF–4.1M

Select item 1085081812.

Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7

Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

Mol Oncol. 2024 Feb; 18(2): 369–385. Published online 2023 Oct 22. doi: 10.1002/1878-0261.13537

PMCID:: PMC10850818

Abstract Article PDF–2.7M

Select item 566346513.

A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome

Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar

Mol Cell. Author manuscript; available in PMC 2017 Oct 31.

Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004

PMCID:: PMC5663465

Abstract Article PDF–2.1M

Select item 642645514.

Mapping the genetic landscape of human cells

Max A. Horlbeck, Albert Xu, Min Wang, Neal K. Bennett, Chong Y. Park, Derek Bogdanoff, Britt Adamson, Eric D. Chow, Martin Kampmann, Tim R. Peterson, Ken Nakamura, Michael A. Fischbach, Jonathan S. Weissman, Luke A. Gilbert

Cell. Author manuscript; available in PMC 2019 Aug 9.

Published in final edited form as: Cell. 2018 Aug 9; 174(4): 953–967.e22. Published online 2018 Jul 19. doi: 10.1016/j.cell.2018.06.010

PMCID:: PMC6426455

Abstract Article PDF–3.6M

Select item 756688115.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 480585516.

Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways

Javier Rodriguez, Ruth Pilkington, Amaya Garcia Munoz, Lan K. Nguyen, Nora Rauch, Susan Kennedy, Naser Monsefi, Ana Herrero, Cormac T. Taylor, Alex von Kriegsheim

Cell Rep. 2016 Mar 22; 14(11): 2745–2760. Published online 2016 Mar 10. doi: 10.1016/j.celrep.2016.02.043

PMCID:: PMC4805855

Abstract Article PDF–4.6M

Select item 1015161517.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 835296418.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 586483219.

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations

Xiaonan Liu, Kari Salokas, Fitsum Tamene, Yaming Jiu, Rigbe G. Weldatsadik, Tiina Öhman, Markku Varjosalo

Nat Commun. 2018; 9: 1188. Published online 2018 Mar 22. doi: 10.1038/s41467-018-03523-2

PMCID:: PMC5864832

Abstract Article PDF–4.5M

Select item 836418120.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

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