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Select item 67548801.

DKK2 Impairs Tumor Immunity Infiltration and Correlates with Poor Prognosis in Pancreatic Ductal Adenocarcinoma

Jianyu Yang, Yongsheng Jiang, Ruizhe He, Wei Liu, Minwei Yang, Lingye Tao, Xueliang Fu, Yang Shen, Jiao Li, Dejun Liu, Yanmiao Huo, Junfeng Zhang, Rong Hua, Zhigang Zhang, Yongwei Sun

J Immunol Res. 2019; 2019: 8656282. Published online 2019 Sep 8. doi: 10.1155/2019/8656282

PMCID:: PMC6754880

Abstract Article PDF–6.5M

Select item 64013982.

Tumor-secreted dickkopf2 accelerates aerobic glycolysis and promotes angiogenesis in colorectal cancer

Fengliu Deng, Rui Zhou, Chuang Lin, Shibin Yang, Hui Wang, Weidong Li, Kehong Zheng, Wandie Lin, Xin Li, Xueqing Yao, Mingxin Pan, Liang Zhao

Theranostics. 2019; 9(4): 1001–1014. Published online 2019 Jan 30. doi: 10.7150/thno.30056

PMCID:: PMC6401398

Abstract Article PDF–2.9M

Select item 62031573.

Prognostic value of DKK2 from the Dickkopf family in human breast cancer

You-Cheng Shao, Xiao-Cui Nie, Guo-Qing Song, Yan Wei, Pu Xia, Xiao-Yan Xu

Int J Oncol. 2018 Dec; 53(6): 2555–2565. Published online 2018 Oct 9. doi: 10.3892/ijo.2018.4588

PMCID:: PMC6203157

Abstract Article PDF–1.8M

Select item 55036244.

Junhao Mu, Tianli Hui, Bianfei Shao, Lili Li, Zhenfang Du, Li Lu, Lin Ye, Shuman Li, Qianqian Li, Qian Xiao, Zhu Qiu, Yan Zhang, Jiangxia Fan, Guosheng Ren, Qian Tao, Tingxiu Xiang

Oncotarget. 2017 Jun 13; 8(24): 39443–39459. Published online 2017 Apr 12. doi: 10.18632/oncotarget.17055

PMCID:: PMC5503624

Abstract Article PDF–16M

Select item 48746285.

Selective Retention of an Inactive Allele of the DKK2 Tumor Suppressor Gene in Hepatocellular Carcinoma

Yung-Feng Lin, Ling-Hui Li, Chih-Hung Lin, Mei-Hua Tsou, Ming-Tai Kiffer Chuang, Keh-Ming Wu, Tsai-Lien Liao, Jian-Chiuan Li, Wei-Jie Wang, Angela Tomita, Beverly Tomita, Shiu-Feng Huang, Shih-Feng Tsai

PLoS Genet. 2016 May; 12(5): e1006051. Published online 2016 May 20. doi: 10.1371/journal.pgen.1006051

PMCID:: PMC4874628

Abstract Article PDF–1.8M

Select item 111598726.

DICKKOPF‐4 and ‐2 genes are upregulated in human colorectal cancer

Akira Matsui, Tatsuya Yamaguchi, Shinya Maekawa, Chikako Miyazaki, Shinichi Takano, Tomoyoshi Uetake, Taisuke Inoue, Masahiko Otaka, Hiroyuki Otsuka, Tadashi Sato, Atsuya Yamashita, Yuka Takahashi, Nobuyuki Enomoto

Cancer Sci. 2009 Oct; 100(10): 1923–1930. Published online 2009 Jul 2. doi: 10.1111/j.1349-7006.2009.01272.x

PMCID:: PMC11159872

Abstract Article PDF–4.9M

Select item 79335957.

G Protein-Coupled Estrogen Receptor Correlates With Dkk2 Expression and Has Prognostic Impact in Ovarian Cancer Patients

Patricia Fraungruber, Till Kaltofen, Sabine Heublein, Christina Kuhn, Doris Mayr, Alexander Burges, Sven Mahner, Philipp Rathert, Udo Jeschke, Fabian Trillsch

Front Endocrinol (Lausanne) 2021; 12: 564002. Published online 2021 Feb 19. doi: 10.3389/fendo.2021.564002

PMCID:: PMC7933595

Abstract Article PDF–1.4M

Select item 78387228.

miR-187-5p Regulates Cell Growth and Apoptosis in Acute Lymphoblastic Leukemia via DKK2

Ye Lou, Lei Liu, Lihui Zhan, Xuewei Wang, Hua Fan

Oncol Res. 2016; 24(2): 89–97. Published online 2016 Jun 7. doi: 10.3727/096504016X14597766487753

PMCID:: PMC7838722

Abstract Article PDF–7.0M

Select item 74472999.

miR-483-3p promotes the osteogenesis of human osteoblasts by targeting Dikkopf 2 (DKK2) and the Wnt signaling pathway

Bin Zhou, Kun Peng, Guoqiang Wang, Weihua Chen, Ping Liu, Fei Chen, Yijun Kang

Int J Mol Med. 2020 Oct; 46(4): 1571–1581. Published online 2020 Aug 6. doi: 10.3892/ijmm.2020.4694

PMCID:: PMC7447299

Abstract Article PDF–2.6M

Select item 530388810.

Concurrent Hypermethylation of SFRP2 and DKK2 Activates the Wnt/β-Catenin Pathway and Is Associated with Poor Prognosis in Patients with Gastric Cancer

Hao Wang, Xiang-Long Duan, Xiao-Li Qi, Lei Meng, Yi-Song Xu, Tong Wu, Peng-Gao Dai

Mol Cells. 2017 Jan 31; 40(1): 45–53. Published online 2017 Jan 26. doi: 10.14348/molcells.2017.2245

PMCID:: PMC5303888

Abstract Article PDF–2.1M

Select item 430257011.

Hypoxia and vitamin D differently contribute to leptin and dickkopf-related protein 2 production in human osteoarthritic subchondral bone osteoblasts

Béatrice Bouvard, Elie Abed, Mélissa Yéléhé-Okouma, Arnaud Bianchi, Didier Mainard, Patrick Netter, Jean-Yves Jouzeau, Daniel Lajeunesse, Pascal Reboul

Arthritis Res Ther. 2014; 16(5): 459. Published online 2014 Oct 14. doi: 10.1186/s13075-014-0459-3

PMCID:: PMC4302570

Abstract Article PDF–1.1M

Select item 361846212.

The roles of Wnt signaling modulators Dickkopf-1 (Dkk1) and Dickkopf-2 (Dkk2) and cell maturation state in osteogenesis on microstructured titanium surfaces

Rene Olivares-Navarrete, Sharon Hyzy, Marco Wieland, Barbara D. Boyan, Zvi Schwartz

Biomaterials. Author manuscript; available in PMC 2013 Apr 6.

Published in final edited form as: Biomaterials. 2010 Mar; 31(8): 2015–2024. Published online 2009 Dec 9. doi: 10.1016/j.biomaterials.2009.11.071

PMCID:: PMC3618462

Abstract Article PDF–1.4M

Select item 264478513.

EWS/ETS Regulates the Expression of the Dickkopf Family in Ewing Family Tumor Cells

Yoshitaka Miyagawa, Hajime Okita, Mitsuko Itagaki, Masashi Toyoda, Yohko U. Katagiri, Junichiro Fujimoto, Jun-ichi Hata, Akihiro Umezawa, Nobutaka Kiyokawa

PLoS One. 2009; 4(2): e4634. Published online 2009 Feb 27. doi: 10.1371/journal.pone.0004634

PMCID:: PMC2644785

Abstract Article PDF–644K

Select item 517309514.

The posterior HOXD locus: Its contribution to phenotype and malignancy of Ewing sarcoma

Kristina von Heyking, Laura Roth, Miriam Ertl, Oxana Schmidt, Julia Calzada-Wack, Frauke Neff, Elizabeth R. Lawlor, Stefan Burdach, Günther H.S. Richter

Oncotarget. 2016 Jul 5; 7(27): 41767–41780. Published online 2016 May 30. doi: 10.18632/oncotarget.9702

PMCID:: PMC5173095

Abstract Article PDF–8.9M

Select item 270905015.

Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer

Tadateru Maehata, Hiroaki Taniguchi, Hiroyuki Yamamoto, Katsuhiko Nosho, Yasushi Adachi, Nobuki Miyamoto, Chie Miyamoto, Noriyuki Akutsu, Satoshi Yamaoka, Fumio Itoh

World J Gastroenterol. 2008 May 7; 14(17): 2702–2714. Published online 2008 May 7. doi: 10.3748/wjg.14.2702

PMCID:: PMC2709050

Abstract Article PDF–2.9M

Select item 13399516.

Regulation of Wnt/LRP Signaling by Distinct Domains of Dickkopf Proteins

Barbara K. Brott, Sergei Y. Sokol

Mol Cell Biol. 2002 Sep; 22(17): 6100–6110. doi: 10.1128/MCB.22.17.6100-6110.2002

PMCID:: PMC133995

Abstract Article PDF–694K

Select item 394036617.

Wnt antagonist gene polymorphisms and renal cancer

Hiroshi Hirata, Yuji Hinoda, Koichi Nakajima, Nobuyuki Kikuno, Soichiro Yamamura, Kazumori Kawakami, Yutaka Suehiro, Z. Laura Tabatabai, Nobuhisa Ishii, Rajvir Dahiya

Cancer. Author manuscript; available in PMC 2014 Mar 3.

Published in final edited form as: Cancer. 2009 Oct 1; 115(19): 4488–4503. doi: 10.1002/cncr.24491

PMCID:: PMC3940366

Abstract Article PDF–531K

Select item 308377718.

The WNT antagonist Dickkopf2 promotes angiogenesis in rodent and human endothelial cells

Jeong-Ki Min, Hongryeol Park, Hyun-Jung Choi, Yonghak Kim, Bo-Jeong Pyun, Vijayendra Agrawal, Byeong-Wook Song, Jongwook Jeon, Yong-Sun Maeng, Seung-Sik Rho, Sungbo Shim, Jin-Ho Chai, Bon-Kyoung Koo, Hyo Jeong Hong, Chae-Ok Yun, Chulhee Choi, Young-Myoung Kim, Ki-Chul Hwang, Young-Guen Kwon

J Clin Invest. 2011 May 2; 121(5): 1882–1893. Published online 2011 Apr 11. doi: 10.1172/JCI42556

PMCID:: PMC3083777

Abstract Article PDF–5.0M

Select item 251700719.

Structural Insight into the Mechanisms of Wnt Signaling Antagonism by Dkk

Lijun Chen, Ke Wang, Youming Shao, Jin Huang, Xiaofeng Li, Jufang Shan, Dianqing Wu, Jie J. Zheng

J Biol Chem. 2008 Aug 22; 283(34): 23364–23370. doi: 10.1074/jbc.M802375200

PMCID:: PMC2517007

Abstract Article PDF–430K

Select item 389456720.

Genome wide association and linkage analyses identified three loci—4q25, 17q23.2, and 10q11.21—associated with variation in leukocyte telomere length: the Long Life Family Study

Joseph H. Lee, Rong Cheng, Lawrence S. Honig, Mary Feitosa, Candace M. Kammerer, Min S. Kang, Nicole Schupf, Shiow J. Lin, Jason L. Sanders, Harold Bae, Todd Druley, Thomas Perls, Kaare Christensen, Michael Province, Richard Mayeux

Front Genet. 2013; 4: 310. Published online 2014 Jan 17. doi: 10.3389/fgene.2013.00310