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Select item 88065841.

Knockdown of STK39 suppressed cell proliferation, migration, and invasion in hepatocellular carcinoma by repressing the phosphorylation of mitogen-activated protein kinase p38

Jian Chen, Luke Zhou, Jie Yang, Hui Xie, Lin Liu, Youwei Li

Bioengineered. 2021; 12(1): 6529–6537. Published online 2021 Sep 14. doi: 10.1080/21655979.2021.1973876

PMCID:: PMC8806584

Abstract Article PDF–2.7M

Select item 85421652.

Variant rs6749447 (T > G) in the serine threonine kinase gene is associated with cardiovascular complications, the Tampere adult population cardiovascular risk study

Tarja Kunnas, Kirsi Määttä, Seppo T. Nikkari

Medicine (Baltimore) 2021 Oct 22; 100(42): e27566. Published online 2021 Oct 22. doi: 10.1097/MD.0000000000027566

PMCID:: PMC8542165

Abstract Article PDF–193K

Select item 70483803.

Identification and characterization of alternative STK39 transcripts within human and mouse kidneys reveals species‐specific regulation of blood pressure

Carlo J. Mercado, Xiaochun Wang, Paul R. Grimm, Paul A. Welling, Yen‐Pei C. Chang

Physiol Rep. 2020 Feb; 8(4): e14379. Published online 2020 Feb 28. doi: 10.14814/phy2.14379

PMCID:: PMC7048380

Abstract Article PDF–1.1M

Select item 53086574.

Role of high expression levels of STK39 in the growth, migration and invasion of non-small cell type lung cancer cells

Zhao Li, Wenzhuo Zhu, Liwen Xiong, Xiaobo Yu, Xi Chen, Qiang Lin

Oncotarget. 2016 Sep 20; 7(38): 61366–61377. Published online 2016 Aug 17. doi: 10.18632/oncotarget.11351

PMCID:: PMC5308657

Abstract Article PDF–8.5M

Select item 48551895.

A meta-analytical assessment of STK39 three well-defined polymorphisms in susceptibility to hypertension

Hualing Yang, Lingyang Ye, Qingxiang Wang, Dongmiao Cai, Qumin Chen, Hongming Pan, Zhanxiang Wang

Sci Rep. 2016; 6: 25290. Published online 2016 May 4. doi: 10.1038/srep25290

PMCID:: PMC4855189

Abstract Article PDF–869K

Select item 46168016.

STK39, But Not BST1, HLA-DQB1, and SPPL2B Polymorphism, Is Associated With Han-Chinese Parkinson's Disease in Taiwan

Kuo-Hsuan Chang, Yih-Ru Wu, Yi-Chun Chen, Hon-Chung Fung, Guey-Jen Lee-Chen, Chiung-Mei Chen

Medicine (Baltimore) 2015 Oct; 94(41): e1690. Published online 2015 Oct 16. doi: 10.1097/MD.0000000000001690

PMCID:: PMC4616801

Abstract Article PDF–178K

Select item 40388177.

Interactive contribution of serine/threonine kinase 39 gene multiple polymorphisms to hypertension among northeastern Han Chinese

Hongye Zhao, Yue Qi, Yuefei Wang, Yanli Wang, Changzhu Lu, Yu Xiao, Bin Wang, Wenquan Niu

Sci Rep. 2014; 4: 5116. Published online 2014 May 30. doi: 10.1038/srep05116

PMCID:: PMC4038817

Abstract Article PDF–248K

Select item 36010808.

STK39 Polymorphism Is Associated with Essential Hypertension: A Systematic Review and Meta-Analysis

Bo Xi, Man Chen, Giriraj R. Chandak, Yue Shen, Li Yan, Juan He, Si-Hua Mou

PLoS One. 2013; 8(3): e59584. Published online 2013 Mar 18. doi: 10.1371/journal.pone.0059584

PMCID:: PMC3601080

Abstract Article PDF–636K

Select item 29229779.

Lack of association between polymorphisms in STK39, a putative thiazide response gene, and blood pressure response to hydrochlorothiazide

Julio D. Duarte, Maximilian T. Lobmeyer, Zhiying Wang, Arlene B. Chapman, John G. Gums, Taimour Y. Langaee, Eric Boerwinkle, Stephen T. Turner, Julie A. Johnson

Pharmacogenet Genomics. Author manuscript; available in PMC 2011 Aug 1.

Published in final edited form as: Pharmacogenet Genomics. 2010 Aug; 20(8): 516–519. doi: 10.1097/FPC.0b013e32833b5958

PMCID:: PMC2922977

Abstract Article PDF–591K

Select item 280316610.

STK39 polymorphisms and blood pressure: an association study in British Caucasians and assessment of cis-acting influences on gene expression

Michael S Cunnington, Chris Kay, Peter J Avery, Bongani M Mayosi, Mauro Santibanez Koref, Bernard Keavney

BMC Med Genet. 2009; 10: 135. Published online 2009 Dec 14. doi: 10.1186/1471-2350-10-135

PMCID:: PMC2803166

Abstract Article PDF–275K

Select item 262920911.

Whole-genome association study identifies STK39 as a hypertension susceptibility gene

Ying Wang, Jeffrey R. O'Connell, Patrick F. McArdle, James B. Wade, Sarah E. Dorff, Sanjiv J. Shah, Xiaolian Shi, Lin Pan, Evadnie Rampersaud, Haiqing Shen, James D. Kim, Arohan R. Subramanya, Nanette I. Steinle, Afshin Parsa, Carole C. Ober, Paul A. Welling, Aravinda Chakravarti, Alan B. Weder, Richard S. Cooper, Braxton D. Mitchell, Alan R. Shuldiner, Yen-Pei C. Chang

Proc Natl Acad Sci U S A. 2009 Jan 6; 106(1): 226–231. Published online 2008 Dec 29. doi: 10.1073/pnas.0808358106

PMCID:: PMC2629209

Abstract Article PDF–638K

Select item 880674112.

Transcription factor specificity protein 1-mediated Serine/threonine kinase 39 upregulation promotes the proliferation, migration, invasion and epithelial–mesenchymal transition of hepatocellular carcinoma cells by activating the transforming growth factor-β1 /Smad2/3 pathway

Jing Wang, Zhenyu Fan, Jia Li, Jingmao Yang, Xiaofei Liu, Jilin Cheng

Bioengineered. 2021; 12(1): 3566–3577. Published online 2021 Jul 19. doi: 10.1080/21655979.2021.1947939

PMCID:: PMC8806741

Abstract Article PDF–3.9M

Select item 831507313.

STK39 promotes breast cancer invasion and metastasis by increasing SNAI1 activity upon phosphorylation

Zhaoping Qiu, Bo Dong, Weijie Guo, Rychahou Piotr, Greg Longmore, Xiuwei Yang, Zhiyong Yu, Jiong Deng, B. Mark Evers, Yadi Wu

Theranostics. 2021; 11(16): 7658–7670. Published online 2021 Jun 11. doi: 10.7150/thno.62406

PMCID:: PMC8315073

Abstract Article PDF–2.9M

Select item 705792214.

MicroRNA-299-5p inhibits cell metastasis in breast cancer by directly targeting serine/threonine kinase 39

Chenxing Li, Aiying Wang, Yanke Chen, Yan Liu, Hui Zhang, Jun Zhou

Oncol Rep. 2020 Apr; 43(4): 1221–1233. Published online 2020 Jan 31. doi: 10.3892/or.2020.7486

PMCID:: PMC7057922

Abstract Article PDF–1.9M

Select item 597288115.

Epstein-Barr Virus (EBV) Latent Protein EBNA3A Directly Targets and Silences the STK39 Gene in B Cells Infected by EBV

Quentin Bazot, Kostas Paschos, Martin J. Allday

J Virol. 2018 Apr 1; 92(7): e01918-17. Prepublished online 2018 Jan 24. Published online 2018 Mar 14. doi: 10.1128/JVI.01918-17

PMCID:: PMC5972881

Abstract Article PDF–3.5M

Select item 496714216.

The Ste20 kinases SPAK and OSR1 travel between cells through exosomes

Rainelli Koumangoye, Eric Delpire

Am J Physiol Cell Physiol. 2016 Jul 1; 311(1): C43–C53. Published online 2016 Apr 27. doi: 10.1152/ajpcell.00080.2016

PMCID:: PMC4967142

Abstract Article

Select item 483978717.

STK39 and WNK1 Are Potential Hypertension Susceptibility Genes in the BELHYPGEN Cohort

Alexandre Persu, Lucie Evenepoel, Yu Jin, Antonella Mendola, Gérard Ngueta, Wen-Yi Yang, Damien Gruson, Sandrine Horman, Jan A. Staessen, Miikka Vikkula

Medicine (Baltimore) 2016 Apr; 95(15): e2968. Published online 2016 Apr 18. doi: 10.1097/MD.0000000000002968

PMCID:: PMC4839787

Abstract Article PDF–296K

Select item 451262518.

Critical role of the SPAK protein kinase CCT domain in controlling blood pressure

Jinwei Zhang, Keith Siew, Thomas Macartney, Kevin M. O'Shaughnessy, Dario R. Alessi

Hum Mol Genet. 2015 Aug 15; 24(16): 4545–4558. Published online 2015 May 20. doi: 10.1093/hmg/ddv185

PMCID:: PMC4512625

Abstract Article PDF–1.0M

Select item 383971319.

Regulation of OSR1 and the sodium, potassium, two chloride cotransporter by convergent signals

Samarpita Sengupta, Andrés Lorente-Rodríguez, Svetlana Earnest, Steve Stippec, Xiaofeng Guo, David C. Trudgian, Hamid Mirzaei, Melanie H. Cobb

Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47): 18826–18831. Published online 2013 Nov 4. doi: 10.1073/pnas.1318676110

PMCID:: PMC3839713

Abstract Article PDF–757K

Select item 353077120.

Calcium-binding protein 39 facilitates molecular interaction between Ste20p proline alanine-rich kinase and oxidative stress response 1 monomers

José Ponce-Coria, Kenneth B. Gagnon, Eric Delpire

Am J Physiol Cell Physiol. 2012 Dec 1; 303(11): C1198–C1205. Published online 2012 Oct 3. doi: 10.1152/ajpcell.00284.2012

PMCID:: PMC3530771

Abstract Article

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