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Select item 111754471.

Glyoxalase 1: Emerging biomarker and therapeutic target in cervical cancer progression

Ji-Young Kim, Ji-Hye Jung, Soryung Jung, Sanghyuk Lee, Hyang Ah Lee, Yung-Taek Ouh, Seok-Ho Hong

PLoS One. 2024; 19(6): e0299345. Published online 2024 Jun 13. doi: 10.1371/journal.pone.0299345

PMCID:: PMC11175447

Abstract Article PDF–1.6M

Select item 106567392.

Association between GLO1 variants and gestational diabetes mellitus susceptibility in a Chinese population: a preliminary study

Qiaoli Zeng, Taili Yang, Wenfeng Wei, Dehua Zou, Yue Wei, Fengqiong Han, Jieyun He, Jinzhi Huang, Runmin Guo

Front Endocrinol (Lausanne) 2023; 14: 1235581. Published online 2023 Nov 3. doi: 10.3389/fendo.2023.1235581

PMCID:: PMC10656739

Abstract Article PDF–1.0M

Select item 89100053.

Emerging Glycation-Based Therapeutics—Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors

Naila Rabbani, Paul J. Thornalley

Int J Mol Sci. 2022 Mar; 23(5): 2453. Published online 2022 Feb 23. doi: 10.3390/ijms23052453

PMCID:: PMC8910005

Abstract Article PDF–1.3M

Select item 87151274.

The activity of glyoxylase 1 is regulated by glucose-responsive phosphorylation on Tyr136

Fabiola Garcia Cortizo, Daniel Pfaff, Angela Wirth, Andrea Schlotterer, Rebekka Medert, Jakob Morgenstern, Tobias Weber, Hans-Peter Hammes, Thomas Fleming, Peter Paul Nawroth, Marc Freichel, Aurelio A. Teleman

Mol Metab. 2022 Jan; 55: 101406. Published online 2021 Nov 25. doi: 10.1016/j.molmet.2021.101406

PMCID:: PMC8715127

Abstract Article PDF–1.8M

Select item 84119115.

Systemic inflammation down-regulates glyoxalase-1 expression: an experimental study in healthy males

Rob G.H. Driessen, Dorien Kiers, Casper G. Schalkwijk, Jean L.J.M. Scheijen, Jelle Gerretsen, Peter Pickkers, Marcel C.G. van de Poll, Iwan C.C. van der Horst, Dennis C.J.J. Bergmans, Matthijs Kox, Bas C.T. van Bussel

Biosci Rep. 2021 Jul 30; 41(7): BSR20210954. Published online 2021 Jul 2. doi: 10.1042/BSR20210954

PMCID:: PMC8411911

Abstract Article PDF–851K

Select item 81066846.

Glyoxalase I disruption and external carbonyl stress impair mitochondrial function in human induced pluripotent stem cells and derived neurons

Tomonori Hara, Manabu Toyoshima, Yasuko Hisano, Shabeesh Balan, Yoshimi Iwayama, Harumi Aono, Yushi Futamura, Hiroyuki Osada, Yuji Owada, Takeo Yoshikawa

Transl Psychiatry. 2021; 11: 275. Published online 2021 May 8. doi: 10.1038/s41398-021-01392-w

PMCID:: PMC8106684

Abstract Article PDF–3.8M

Select item 74323037.

Resveratrol, Curcumin and Piperine Alter Human Glyoxalase 1 in MCF-7 Breast Cancer Cells

Betina Schmidt, Christian Ferreira, Carlos Luan Alves Passos, Jerson Lima Silva, Eliane Fialho

Int J Mol Sci. 2020 Aug; 21(15): 5244. Published online 2020 Jul 24. doi: 10.3390/ijms21155244

PMCID:: PMC7432303

Abstract Article PDF–3.4M

Select item 68188038.

Common variants in glyoxalase I do not increase chronic pancreatitis risk

Tom Kaune, Marcus Hollenbach, Bettina Keil, Jian-Min Chen, Emmanuelle Masson, Carla Becker, Marko Damm, Claudia Ruffert, Robert Grützmann, Albrecht Hoffmeister, Rene H. M. te Morsche, Giulia Martina Cavestro, Raffaella Alessia Zuppardo, Adrian Saftoiu, Ewa Malecka-Panas, Stanislaw Głuszek, Peter Bugert, Markus M. Lerch, Frank Ulrich Weiss, Wen-Bin Zou, Zhuan Liao, Peter Hegyi, Joost PH Drenth, Jan Riedel, Claude Férec, Markus Scholz, Holger Kirsten, Andrea Tóth, Maren Ewers, Heiko Witt, Heidi Griesmann, Patrick Michl, Jonas Rosendahl

PLoS One. 2019; 14(10): e0222927. Published online 2019 Oct 29. doi: 10.1371/journal.pone.0222927

PMCID:: PMC6818803

Abstract Article PDF–1.0M

Select item 67353959.

Glyoxalase 1 Prevents Chronic Hyperglycemia Induced Heart-Explant Derived Cell Dysfunction

Melanie Villanueva, Connor Michie, Sandrine Parent, Georges N Kanaan, Ghazaleh Rafatian, Pushpinder Kanda, Bin Ye, Wenbin Liang, Mary-Ellen Harper, Darryl R Davis

Theranostics. 2019; 9(19): 5720–5730. Published online 2019 Aug 9. doi: 10.7150/thno.36639

PMCID:: PMC6735395

Abstract Article PDF–1.5M

Select item 637269510.

Three-dimensional alteration of neurites in schizophrenia

Ryuta Mizutani, Rino Saiga, Akihisa Takeuchi, Kentaro Uesugi, Yasuko Terada, Yoshio Suzuki, Vincent De Andrade, Francesco De Carlo, Susumu Takekoshi, Chie Inomoto, Naoya Nakamura, Itaru Kushima, Shuji Iritani, Norio Ozaki, Soichiro Ide, Kazutaka Ikeda, Kenichi Oshima, Masanari Itokawa, Makoto Arai

Transl Psychiatry. 2019; 9: 85. Published online 2019 Feb 12. doi: 10.1038/s41398-019-0427-4

PMCID:: PMC6372695

Abstract Article PDF–2.3M

Select item 590812511.

Glyoxalase 1 sustains the metastatic phenotype of prostate cancer cells via EMT control

Cinzia Antognelli, Rodolfo Cecchetti, Francesca Riuzzi, Matthew J. Peirce, Vincenzo N. Talesa

J Cell Mol Med. 2018 May; 22(5): 2865–2883. Published online 2018 Mar 5. doi: 10.1111/jcmm.13581

PMCID:: PMC5908125

Abstract Article PDF–1.4M

Select item 544673012.

Glyoxalase 1 expression is associated with an unfavorable prognosis of oropharyngeal squamous cell carcinoma

Nele Kreycy, Christiane Gotzian, Thomas Fleming, Christa Flechtenmacher, Niels Grabe, Peter Plinkert, Jochen Hess, Karim Zaoui

BMC Cancer. 2017; 17: 382. Published online 2017 May 26. doi: 10.1186/s12885-017-3367-5

PMCID:: PMC5446730

Abstract Article PDF–1.3M

Select item 529780613.

Glycative Stress and Its Defense Machinery Glyoxalase 1 in Renal Pathogenesis

Yosuke Hirakawa, Reiko Inagi

Int J Mol Sci. 2017 Jan; 18(1): 174. Published online 2017 Jan 17. doi: 10.3390/ijms18010174

PMCID:: PMC5297806

Abstract Article PDF–470K

Select item 518793314.

Modulation of GLO1 Expression Affects Malignant Properties of Cells

Antje Hutschenreuther, Marina Bigl, Nasr Y. A. Hemdan, Tewodros Debebe, Frank Gaunitz, Gerd Birkenmeier

Int J Mol Sci. 2016 Dec; 17(12): 2133. Published online 2016 Dec 18. doi: 10.3390/ijms17122133

PMCID:: PMC5187933

Abstract Article PDF–2.2M

Select item 512718815.

Glyoxalase 1-knockdown in human aortic endothelial cells – effect on the proteome and endothelial function estimates

Bernd Stratmann, Britta Engelbrecht, Britta C. Espelage, Nadine Klusmeier, Janina Tiemann, Thomas Gawlowski, Yvonne Mattern, Martin Eisenacher, Helmut E. Meyer, Naila Rabbani, Paul J. Thornalley, Diethelm Tschoepe, Gereon Poschmann, Kai Stühler

Sci Rep. 2016; 6: 37737. Published online 2016 Nov 29. doi: 10.1038/srep37737

PMCID:: PMC5127188

Abstract Article PDF–2.1M

Select item 497576816.

Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics

Naila Rabbani, Mingzhan Xue, Paul J. Thornalley

Glycoconj J. 2016; 33: 513–525. Published online 2016 Jul 12. doi: 10.1007/s10719-016-9705-z

PMCID:: PMC4975768

Abstract Article PDF–856K

Select item 472801817.

Neuronal overexpression of Glo1 or amygdalar microinjection of methylglyoxal is sufficient to regulate anxiety-like behavior in mice

K. M. J. McMurray, X. Du, M. Brownlee, A. A. Palmer

Behav Brain Res. Author manuscript; available in PMC 2017 Mar 15.

Published in final edited form as: Behav Brain Res. 2016 Mar 15; 301: 119–123. Published online 2015 Dec 19. doi: 10.1016/j.bbr.2015.12.026

PMCID:: PMC4728018

Abstract Article PDF–965K

Select item 432688618.

Glyoxalase I reduces glycative and oxidative stress and prevents age-related endothelial dysfunction through modulation of endothelial nitric oxide synthase phosphorylation

Airi Jo-Watanabe, Takamoto Ohse, Hiroaki Nishimatsu, Masao Takahashi, Yoichiro Ikeda, Takehiko Wada, Jun-ichi Shirakawa, Ryoji Nagai, Toshio Miyata, Tetsuo Nagano, Yasunobu Hirata, Reiko Inagi, Masaomi Nangaku

Aging Cell. 2014 Jun; 13(3): 519–528. Published online 2014 Feb 24. doi: 10.1111/acel.12204

PMCID:: PMC4326886

Abstract Article PDF–679K

Select item 406989019.

Glo1 genetic amplification as a potential therapeutic target in hepatocellular carcinoma

Shirong Zhang, Xiaodong Liang, Xiaoliang Zheng, Haixiu Huang, Xufeng Chen, Kan Wu, Bing Wang, Shenglin Ma

Int J Clin Exp Pathol. 2014; 7(5): 2079–2090. Published online 2014 Apr 15.

PMCID:: PMC4069890

Abstract Article PDF–1.3M

Select item 376935620.

Glyoxalase 1−419C>A Variant Is Associated with Oxidative Stress: Implications in Prostate Cancer Progression

Cinzia Antognelli, Letizia Mezzasoma, Ettore Mearini, Vincenzo Nicola Talesa

PLoS One. 2013; 8(9): e74014. Published online 2013 Sep 10. doi: 10.1371/journal.pone.0074014

PMCID:: PMC3769356

Abstract Article PDF–357K

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