PMC Links for Gene (Select 2805) - PMC

Links from Gene

Items: 1 to 20 of 61

<< First< Prev

Page of 4

Select item 97355201.

Tumor Cell Derived Exosomal GOT1 Suppresses Tumor Cell Ferroptosis to Accelerate Pancreatic Cancer Progression by Activating Nrf2/HO-1 Axis via Upregulating CCR2 Expression

Yao Guo, Taoyu Chen, Xueyi Liang, Shanmiao Gou, Jiongxin Xiong, Jing Cui, Tao Peng

Cells. 2022 Dec; 11(23): 3893. Published online 2022 Dec 2. doi: 10.3390/cells11233893

PMCID:: PMC9735520

Abstract Article PDF–6.2M

Select item 83578412.

GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis

Daniel M. Kremer, Barbara S. Nelson, Lin Lin, Emily L. Yarosz, Christopher J. Halbrook, Samuel A. Kerk, Peter Sajjakulnukit, Amy Myers, Galloway Thurston, Sean W. Hou, Eileen S. Carpenter, Anthony C. Andren, Zeribe C. Nwosu, Nicholas Cusmano, Stephanie Wisner, Nneka E. Mbah, Mengrou Shan, Nupur K. Das, Brian Magnuson, Andrew C. Little, Milan R. Savani, Johanna Ramos, Tina Gao, Stephen A. Sastra, Carmine F. Palermo, Michael A. Badgley, Li Zhang, John M. Asara, Samuel K. McBrayer, Marina Pasca di Magliano, Howard C. Crawford, Yatrik M. Shah, Kenneth P. Olive, Costas A. Lyssiotis

Nat Commun. 2021; 12: 4860. Published online 2021 Aug 11. doi: 10.1038/s41467-021-24859-2

PMCID:: PMC8357841

Abstract Article PDF–2.6M

Select item 77128323.

Moderate to severe liver siderosis and raised AST are independent risk factors for vitamin D insufficiency in β-thalassemia patients

Hadi Darvishi-Khezri, Hossein Karami, Mohammad Naderisorki, Mohammad Zahedi, Alireza Razavi, Mehrnoush Kosaryan, Aily Aliasgharian

Sci Rep. 2020; 10: 21164. Published online 2020 Dec 3. doi: 10.1038/s41598-020-78230-4

PMCID:: PMC7712832

Abstract Article PDF–968K

Select item 73005314.

Elevated serum aspartate aminotransferase level identifies patients with coronavirus disease 2019 and predicts the length of hospital stay

Xuexiang Gu, Xiangyu Li, Xusheng An, Shufeng Yang, Shangnong Wu, Xiaozhong Yang, Honggang Wang

J Clin Lab Anal. 2020 Jul; 34(7): e23391. Published online 2020 Jun 2. doi: 10.1002/jcla.23391

PMCID:: PMC7300531

Abstract Article PDF–282K

Select item 61355125.

Dimerization misalignment in human glutamate-oxaloacetate transaminase variants is the primary factor for PLP release

Jesi Lee, Trevor Gokey, Dylan Ting, Zheng-Hui He, Anton B. Guliaev

PLoS One. 2018; 13(9): e0203889. Published online 2018 Sep 12. doi: 10.1371/journal.pone.0203889

PMCID:: PMC6135512

Abstract Article PDF–14M

Select item 59488736.

Inhibition of glutamate oxaloacetate transaminase 1 in cancer cell lines results in altered metabolism with increased dependency of glucose

Xiaoshan Zhou, Sophie Curbo, Fuqiang Li, Shuba Krishnan, Anna Karlsson

BMC Cancer. 2018; 18: 559. Published online 2018 May 11. doi: 10.1186/s12885-018-4443-1

PMCID:: PMC5948873

Abstract Article PDF–8.0M

Select item 54887217.

GOT1-Mediated Anaplerotic Glutamine Metabolism Regulates Chronic Acidosis Stress In Pancreatic Cancer Cells

Jaime Abrego, Venugopal Gunda, Enza Vernucci, Surendra K. Shukla, Ryan J. King, Aneesha Dasgupta, Gennifer Goode, Divya Murthy, Fang Yu, Pankaj K. Singh

Cancer Lett. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Cancer Lett. 2017 Aug 1; 400: 37–46. Published online 2017 Apr 26. doi: 10.1016/j.canlet.2017.04.029

PMCID:: PMC5488721

Abstract Article PDF–1.5M

Select item 48487548.

Association of aspartate aminotransferase with mortality in hemodialysis patients

Vanessa Ravel, Elani Streja, Miklos Z. Molnar, Sepideh Rezakhani, Melissa Soohoo, Csaba P. Kovesdy, Kamyar Kalantar-Zadeh, Hamid Moradi

Nephrol Dial Transplant. 2016 May; 31(5): 814–822. Published online 2015 Sep 1. doi: 10.1093/ndt/gfv310

PMCID:: PMC4848754

Abstract Article PDF–438K

Select item 44142089.

GOT1/AST1 expression status as a prognostic biomarker in pancreatic ductal adenocarcinoma

Fenja M Feld, Philipp D Nagel, Stephanie E Weissinger, Claudia Welke, Albrecht Stenzinger, Peter Möller, Jochen K Lennerz

Oncotarget. 2015 Feb; 6(6): 4516–4526. Published online 2015 Feb 19. doi: 10.18632/oncotarget.2799

PMCID:: PMC4414208

Abstract Article PDF–3.8M

Select item 360885510.

Genome-wide association study identifies genetic variants in GOT1 determining serum aspartate aminotransferase levels

Haiqing Shen, Coleen Damcott, Scott R Shuldiner, Sumbul Chai, Rongze Yang, Hong Hu, Quince Gibson, Kathleen A Ryan, Braxton D Mitchell, Da-Wei Gong

J Hum Genet. Author manuscript; available in PMC 2013 Mar 27.

Published in final edited form as: J Hum Genet. 2011 Nov; 56(11): 801–805. Published online 2011 Sep 8. doi: 10.1038/jhg.2011.105

PMCID:: PMC3608855

Abstract Article PDF–1.4M

Select item 818495111.

Aspartate aminotransferase to alanine aminotransferase ratio is associated with frailty and mortality in older patients with heart failure

Daichi Maeda, Nobuyuki Kagiyama, Kentaro Jujo, Kazuya Saito, Kentaro Kamiya, Hiroshi Saito, Yuki Ogasahara, Emi Maekawa, Masaaki Konishi, Takeshi Kitai, Kentaro Iwata, Hiroshi Wada, Masaru Hiki, Taishi Dotare, Tsutomu Sunayama, Takatoshi Kasai, Hirofumi Nagamatsu, Tetsuya Ozawa, Katsuya Izawa, Shuhei Yamamoto, Naoki Aizawa, Ryusuke Yonezawa, Kazuhiro Oka, Shin-ichi Momomura, Yuya Matsue

Sci Rep. 2021; 11: 11957. Published online 2021 Jun 7. doi: 10.1038/s41598-021-91368-z

PMCID:: PMC8184951

Abstract Article PDF–1.0M

Select item 776452612.

Ambulatory end-stage liver disease in Ghana; patient profile and utility of alpha fetoprotein and aspartate aminotransferase: platelet ratio index

Yvonne Ayerki Nartey, Yaw Asante Awuku, Adwoa Agyei-Nkansah, Amoako Duah, Sally Afua Bampoh, Joshua Ayawin, Shadrack Osei Asibey, Niklas K. Björkström, Weimin Ye, Mary Yeboah Afihene, Lewis Rowland Roberts, Amelie Plymoth

BMC Gastroenterol. 2020; 20: 428. Published online 2020 Dec 26. doi: 10.1186/s12876-020-01581-9

PMCID:: PMC7764526

Abstract Article PDF–1000K

Select item 729830513.

Clinical implications of aminotransferase elevation in hospitalised infants aged 8‐90 days with respiratory virus detection

Sang Gyeom Kim, Yu Na Oh, Joon Kee Lee

Influenza Other Respir Viruses. 2020 Jul; 14(4): 429–435. Published online 2020 Mar 10. doi: 10.1111/irv.12732

PMCID:: PMC7298305

Abstract Article PDF–292K

Select item 566114614.

HIF‐2α regulates non‐canonical glutamine metabolism via activation of PI3K/mTORC2 pathway in human pancreatic ductal adenocarcinoma

Wenzhu Li, Changhao Chen, Xiaohui Zhao, Huilin Ye, Yue Zhao, Zhiqiang Fu, Wenwei Pan, Shangyou Zheng, Lusheng Wei, Tianwen Nong, Zhihua Li, Rufu Chen

J Cell Mol Med. 2017 Nov; 21(11): 2896–2908. Published online 2017 May 24. doi: 10.1111/jcmm.13202

PMCID:: PMC5661146

Abstract Article PDF–4.3M

Select item 553665515.

Early abnormal liver enzyme levels may increase the prevalence of human cytomegalovirus antigenaemia after hematopoietic stem cell transplantation

Baning Ye, Hong Zhao

J Int Med Res. 2017 Apr; 45(2): 673–679. Published online 2017 Feb 19. doi: 10.1177/0300060516689013

PMCID:: PMC5536655

Abstract Article PDF–149K

Select item 548737216.

Correlations of Complete Blood Count with Alanine and Aspartate Transaminase in Chinese Subjects and Prediction Based on Back-Propagation Artificial Neural Network (BP-ANN)

Jiong Yu, Qiaoling Pan, Jinfeng Yang, Chengxing Zhu, Linfeng Jin, Guangshu Hao, Xiaowei Shi, Hongcui Cao, Feiyan Lin

Med Sci Monit. 2017; 23: 3001–3009. Published online 2017 Jun 19. doi: 10.12659/MSM.901202

PMCID:: PMC5487372

Abstract Article PDF–444K

Select item 510786917.

Association of the Aspartate Aminotransferase to Alanine Aminotransferase Ratio with BNP Level and Cardiovascular Mortality in the General Population: The Yamagata Study 10-Year Follow-Up

Miyuki Yokoyama, Tetsu Watanabe, Yoichiro Otaki, Hiroki Takahashi, Takanori Arimoto, Tetsuro Shishido, Takuya Miyamoto, Tsuneo Konta, Yoko Shibata, Makoto Daimon, Yoshiyuki Ueno, Takeo Kato, Takamasa Kayama, Isao Kubota

Dis Markers. 2016; 2016: 4857917. Published online 2016 Oct 31. doi: 10.1155/2016/4857917