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Select item 98618851.

Absence of Scaffold Protein Tks4 Disrupts Several Signaling Pathways in Colon Cancer Cells

Mevan Jacksi, Eva Schad, László Buday, Agnes Tantos

Int J Mol Sci. 2023 Jan; 24(2): 1310. Published online 2023 Jan 9. doi: 10.3390/ijms24021310

PMCID:: PMC9861885

Abstract Article PDF–4.4M

Select item 69126132.

Absence of the Tks4 Scaffold Protein Induces Epithelial-Mesenchymal Transition-Like Changes in Human Colon Cancer Cells

Bálint Szeder, Júlia Tárnoki-Zách, Dóra Lakatos, Virág Vas, Gyöngyi Kudlik, Balázs Merő, Kitti Koprivanacz, László Bányai, Lilla Hámori, Gergely Róna, András Czirók, András Füredi, László Buday

Cells. 2019 Nov; 8(11): 1343. Published online 2019 Oct 29. doi: 10.3390/cells8111343

PMCID:: PMC6912613

Abstract Article PDF–2.8M

Select item 45040773.

Accumulation of the PX domain mutant Frank-ter Haar syndrome protein Tks4 in aggresomes

Csaba Ádám, Anna Fekete, Gábor Bőgel, Zsuzsanna Németh, Natália Tőkési, Judit Ovádi, Károly Liliom, Szabolcs Pesti, Miklós Geiszt, László Buday

Cell Commun Signal. 2015; 13: 33. Published online 2015 Jul 17. doi: 10.1186/s12964-015-0108-8

PMCID:: PMC4504077

Abstract Article PDF–1.9M

Select item 40232074.

Mutations in SH3PXD2B cause Borrone dermato-cardio-skeletal syndrome

Gabrielle R Wilson, Jasmine Sunley, Katherine R Smith, Kate Pope, Catherine J Bromhead, Elizabeth Fitzpatrick, Maja Di Rocco, Maurice van Steensel, David J Coman, Richard J Leventer, Martin B Delatycki, David J Amor, Melanie Bahlo, Paul J Lockhart

Eur J Hum Genet. 2014 Jun; 22(6): 741–747. Published online 2013 Oct 9. doi: 10.1038/ejhg.2013.229

PMCID:: PMC4023207

Abstract Article PDF–702K

Select item 39446985.

Expression, purification and preliminary crystallographic studies of the C-terminal SH3 domain of human Tks4

Yuxin Huang, Huolian Qian, Xiaoying Wang, Zhong Cheng, Jixia Ren, Weichen Zhao, Yong Xie

Acta Crystallogr F Struct Biol Commun. 2014 Mar 1; 70(Pt 3): 343–346. Published online 2014 Feb 19. doi: 10.1107/S2053230X14001952

PMCID:: PMC3944698

Abstract Article PDF–352K

Select item 35321756.

Frank-ter Haar syndrome associated with sagittal craniosynostosis and raised intracranial pressure

Charlotte L Bendon, Aimée L Fenwick, Jane A Hurst, Gudrun Nürnberg, Peter Nürnberg, Steven A Wall, Andrew OM Wilkie, David Johnson

BMC Med Genet. 2012; 13: 104. Published online 2012 Nov 9. doi: 10.1186/1471-2350-13-104

PMCID:: PMC3532175

Abstract Article PDF–701K

Select item 34253877.

Cell migration and invasion in human disease: the Tks adaptor proteins

Sara A. Courtneidge

Biochem Soc Trans. Author manuscript; available in PMC 2013 Feb 1.

Published in final edited form as: Biochem Soc Trans. 2012 Feb; 40(1): 129–132. doi: 10.1042/BST20110685

PMCID:: PMC3425387

Abstract Article PDF–1000K

Select item 33243578.

Localization of SH3PXD2B in human eyes and detection of rare variants in patients with anterior segment diseases and glaucoma

Mao Mao, Frances Solivan-Timpe, Ben R. Roos, Robert F. Mullins, Thomas A. Oetting, Young H. Kwon, Peter M. Brzeskiewicz, Edwin M. Stone, Wallace L.M. Alward, Michael G. Anderson, John H. Fingert

Mol Vis. 2012; 18: 705–713. Published online 2012 Mar 26.

PMCID:: PMC3324357

Abstract Article PDF–864K

Select item 31603129.

The Homolog of the Five SH3-Domain Protein (HOFI/SH3PXD2B) Regulates Lamellipodia Formation and Cell Spreading

Árpád Lányi, Mónika Baráth, Zalán Péterfi, Gábor Bőgel, Anna Orient, Tünde Simon, Enikő Petrovszki, Katalin Kis-Tóth, Gábor Sirokmány, Éva Rajnavölgyi, Cox Terhorst, László Buday, Miklós Geiszt

PLoS One. 2011; 6(8): e23653. Published online 2011 Aug 23. doi: 10.1371/journal.pone.0023653

PMCID:: PMC3160312

Abstract Article PDF–714K

Select item 289314010.

Regulation of Cancer Invasion by Reactive Oxygen Species and Tks Family Scaffold Proteins

Alissa M. Weaver

Sci Signal. Author manuscript; available in PMC 2010 Jun 28.

Published in final edited form as: Sci Signal. 2009 Sep 15; 2(88): pe56. Published online 2009 Sep 15. doi: 10.1126/scisignal.288pe56

PMCID:: PMC2893140

Abstract Article PDF–486K

Select item 1104792011.

Morphological Changes Induced by TKS4 Deficiency Can Be Reversed by EZH2 Inhibition in Colorectal Carcinoma Cells

Mevan Jacksi, Eva Schad, Agnes Tantos

Biomolecules. 2024 Apr; 14(4): 445. Published online 2024 Apr 5. doi: 10.3390/biom14040445

PMCID:: PMC11047920

Abstract Article PDF–3.7M

Select item 1060689012.

Studying the Association of TKS4 and CD2AP Scaffold Proteins and Their Implications in the Partial Epithelial–Mesenchymal Transition (EMT) Process

Anita Kurilla, Loretta László, Tamás Takács, Álmos Tilajka, Laura Lukács, Julianna Novák, Rita Pancsa, László Buday, Virág Vas

Int J Mol Sci. 2023 Oct; 24(20): 15136. Published online 2023 Oct 13. doi: 10.3390/ijms242015136

PMCID:: PMC10606890

Abstract Article PDF–3.5M

Select item 645395213.

Significance of the Tks4 scaffold protein in bone tissue homeostasis

Virag Vas, Tamás Kovács, Szandra Körmendi, Andrea Bródy, Gyöngyi Kudlik, Bálint Szeder, Diána Mező, Dóra Kállai, Kitti Koprivanacz, Balázs L. Merő, Metta Dülk, József Tóvári, Péter Vajdovich, Ş. Neslihan Şenel, Ilknur Özcan, Zsuzsanna Helyes, Csaba Dobó-Nagy, László Buday

Sci Rep. 2019; 9: 5781. Published online 2019 Apr 8. doi: 10.1038/s41598-019-42250-6

PMCID:: PMC6453952

Abstract Article PDF–2.9M

Select item 343896114.

Frank-ter Haar Syndrome Protein Tks4 Regulates Epidermal Growth Factor-dependent Cell Migration

Gábor Bögel, Annamária Gujdár, Miklós Geiszt, Árpád Lányi, Anna Fekete, Szabolcs Sipeki, Julian Downward, László Buday

J Biol Chem. 2012 Sep 7; 287(37): 31321–31329. Published online 2012 Jul 24. doi: 10.1074/jbc.M111.324897

PMCID:: PMC3438961

Abstract Article PDF–1.5M

Select item 282017215.

Disruption of the Podosome Adaptor Protein TKS4 (SH3PXD2B) Causes the Skeletal Dysplasia, Eye, and Cardiac Abnormalities of Frank-Ter Haar Syndrome

Zafar Iqbal, Pilar Cejudo-Martin, Arjan de Brouwer, Bert van der Zwaag, Pilar Ruiz-Lozano, M. Cecilia Scimia, James D. Lindsey, Robert Weinreb, Beate Albrecht, Andre Megarbane, Yasemin Alanay, Ziva Ben-Neriah, Mariangela Amenduni, Rosangela Artuso, Joris A. Veltman, Ellen van Beusekom, Astrid Oudakker, José Luis Millán, Raoul Hennekam, Ben Hamel, Sara A. Courtneidge, Hans van Bokhoven

Am J Hum Genet. 2010 Feb 12; 86(2): 254–261. doi: 10.1016/j.ajhg.2010.01.009

PMCID:: PMC2820172

Abstract Article PDF–711K

Select item 264927316.

The Novel Adaptor Protein Tks4 (SH3PXD2B) Is Required for Functional Podosome Formation

Matthew D. Buschman, Paul A. Bromann, Pilar Cejudo-Martin, Fang Wen, Ian Pass, Sara A. Courtneidge

Mol Biol Cell. 2009 Mar 1; 20(5): 1302–1311. doi: 10.1091/mbc.E08-09-0949

PMCID:: PMC2649273

Abstract Article PDF–528K

Select item 677975817.

Enhanced endothelial motility and multicellular sprouting is mediated by the scaffold protein TKS4

Elod Mehes, Monika Barath, Marton Gulyas, Edina Bugyik, Miklos Geiszt, Arpad Szoor, Arpad Lanyi, Andras Czirok

Sci Rep. 2019; 9: 14363. Published online 2019 Oct 7. doi: 10.1038/s41598-019-50915-5

Correction in:: Sci Rep. 2020; 10: 12293.

PMCID:: PMC6779758

Abstract Article PDF–8.5M

Select item 534665418.

The role of Tks adaptor proteins in invadopodia formation, growth and metastasis of melanoma

Shinji Iizuka, Christopher Abdullah, Matthew D. Buschman, Begoña Diaz, Sara A. Courtneidge

Oncotarget. 2016 Nov 29; 7(48): 78473–78486. Published online 2016 Oct 27. doi: 10.18632/oncotarget.12954

PMCID:: PMC5346654

Abstract Article PDF–6.3M

Select item 299375519.

c-Src–Mediated Phosphorylation of NoxA1 and Tks4 Induces the Reactive Oxygen Species (ROS)–Dependent Formation of Functional Invadopodia in Human Colon Cancer Cells

Davide Gianni, Nicolas Taulet, Céline DerMardirossian, Gary M. Bokoch

Mol Biol Cell. 2010 Dec 1; 21(23): 4287–4298. doi: 10.1091/mbc.E10-08-0685

PMCID:: PMC2993755

Abstract Article PDF–1.6M

Select item 266979720.

Non-replication of an association of CTNNBL1 polymorphisms and obesity in a population of Central European ancestry

Carla IG Vogel, Brandon Greene, André Scherag, Timo D Müller, Susann Friedel, Harald Grallert, Iris M Heid, Thomas Illig, H-Erich Wichmann, Helmut Schäfer, Johannes Hebebrand, Anke Hinney

BMC Med Genet. 2009; 10: 14. Published online 2009 Feb 19. doi: 10.1186/1471-2350-10-14

PMCID:: PMC2669797

Abstract Article PDF–688K

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PMC Links for Gene (Select 285590) (50)
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zw76d05.r1 Soares_testis_NHT Homo sapiens cDNA clone IMAGE:782121 5', mRNA seque...
zw76d05.r1 Soares_testis_NHT Homo sapiens cDNA clone IMAGE:782121 5', mRNA sequence
gi|2115099|gnl|dbEST|1075962|gb|AA4 .1|

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Interleukin-12 effect on peripheral blood mononuclear cells (HG-U133B)
Interleukin-12 effect on peripheral blood mononuclear cells (HG-U133B)
Accession: GDS3498

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