PMC Links for Gene (Select 2878) - PMC

Marko Markovic, Jovan Ranin, Zoran Bukumiric, Djurdja Jerotic, Ana Savic-Radojevic, Marija Pljesa-Ercegovac, Tatjana Djukic, Marko Ercegovac, Milika Asanin, Ivana Milosevic, Goran Stevanovic, Tatjana Simic, Vesna Coric, Marija Matic

Int J Mol Sci. 2023 Nov; 24(22): 16151. Published online 2023 Nov 10. doi: 10.3390/ijms242216151

PMCID:: PMC10671662

Abstract Article PDF–292K

Select item 104563384.

GPX3 rs8177412 Polymorphism Modifies Risk of Upper Urothelial Tumors in Patients with Balkan Endemic Nephropathy

Zana Radic Savic, Vesna Coric, Stojko Vidovic, Vanja Vidovic, Jelena Becarevic, Irina Milovac, Zorica Reljic, Bosa Mirjanic-Azaric, Ranko Skrbic, Radoslav Gajanin, Marija Matic, Tatjana Simic

Medicina (Kaunas) 2023 Aug; 59(8): 1421. Published online 2023 Aug 4. doi: 10.3390/medicina59081421

PMCID:: PMC10456338

Abstract Article PDF–364K

Select item 101223075.

Glutathione peroxidase 3 is a novel clinical diagnostic biomarker and potential therapeutic target for neutrophils in rheumatoid arthritis

Tao Chen, Zhen Zhou, Minge Peng, Huifang Hu, Rui Sun, Jiayi Xu, Chenxi Zhu, Yanhong Li, Qiuping Zhang, Yubin Luo, Bin Yang, Lunzhi Dai, Yi Liu, Luis E. Muñoz, Liesu Meng, Martin Herrmann, Yi Zhao

Arthritis Res Ther. 2023; 25: 66. Published online 2023 Apr 22. doi: 10.1186/s13075-023-03043-5

PMCID:: PMC10122307

Abstract Article PDF–7.8M

Select item 78014346.

Legumain promotes tubular ferroptosis by facilitating chaperone-mediated autophagy of GPX4 in AKI

Chuan’ai Chen, Dekun Wang, Yangyang Yu, Tianyuan Zhao, Ningning Min, Yan Wu, Lichun Kang, Yong Zhao, Lingfang Du, Mianzhi Zhang, Junbo Gong, Zhujun Zhang, Yuying Zhang, Xue Mi, Shijing Yue, Xiaoyue Tan

Cell Death Dis. 2021 Jan; 12(1): 65. Published online 2021 Jan 11. doi: 10.1038/s41419-020-03362-4

PMCID:: PMC7801434

Abstract Article PDF–3.8M

Select item 76961557.

Involvement of GPx-3 in the Reciprocal Control of Redox Metabolism in the Leukemic Niche

Christine Vignon, Christelle Debeissat, Jérôme Bourgeais, Nathalie Gallay, Farah Kouzi, Adrienne Anginot, Frédéric Picou, Philippe Guardiola, Elfi Ducrocq, Amélie Foucault, Noémie Ravalet, Louis-Romée Le Nail, Jorge Domenech, Marie-Christine Béné, Marie-Caroline Le Bousse-Kerdilès, Emmanuel Gyan, Olivier Herault

Int J Mol Sci. 2020 Nov; 21(22): 8584. Published online 2020 Nov 14. doi: 10.3390/ijms21228584

PMCID:: PMC7696155

Abstract Article PDF–3.2M

Select item 68595818.

GPx3 supports ovarian cancer progression by manipulating the extracellular redox environment

Beth L. Worley, Yeon Soo Kim, Jennifer Mardini, Rameez Zaman, Kelly E. Leon, Piyushi Gupta Vallur, Asvelt Nduwumwami, Joshua I. Warrick, Patrick F. Timmins, Joshua P. Kesterson, Rébécca Phaëton, Nam Y. Lee, Vonn Walter, Lauren Endres, Karthikeyan Mythreye, Katherine M. Aird, Nadine Hempel

Redox Biol. 2019 Jul; 25: 101051. Published online 2018 Nov 17. doi: 10.1016/j.redox.2018.11.009

PMCID:: PMC6859581

Abstract Article PDF–4.3M

Select item 68577809.

Long noncoding RNA glutathione peroxidase 3–antisense inhibits lens epithelial cell apoptosis by upregulating glutathione peroxidase 3 expression in age-related cataract

Yuanyuan Tu, Lele Li, Bai Qin, Jian Wu, Tianyu Cheng, Lihua Kang, Huaijin Guan

Mol Vis. 2019; 25: 734–744. Published online 2019 Nov 14.

PMCID:: PMC6857780

Abstract Article PDF–4.2M

Select item 634132410.

Effects of Weight Loss on Glutathione Peroxidase 3 Serum Concentrations and Adipose Tissue Expression in Human Obesity

Julia Langhardt, Gesine Flehmig, Nora Klöting, Stefanie Lehmann, Thomas Ebert, Matthias Kern, Michael R. Schön, Daniel Gärtner, Tobias Lohmann, Miriam Dressler, Mathias Fasshauer, Peter Kovacs, Michael Stumvoll, Arne Dietrich, Matthias Blüher

Obes Facts. 2018 Dec; 11(6): 475–490. Published online 2018 Dec 11. doi: 10.1159/000494295

PMCID:: PMC6341324

Abstract Article PDF–540K

Select item 616001311.

GPx3-mediated redox signaling arrests the cell cycle and acts as a tumor suppressor in lung cancer cell lines

Byung Chull An, Yoo-Duk Choi, In-Jae Oh, Ju Han Kim, Jae-Il Park, Seung-won Lee

PLoS One. 2018; 13(9): e0204170. Published online 2018 Sep 27. doi: 10.1371/journal.pone.0204170

PMCID:: PMC6160013

Abstract Article PDF–14M

Select item 526956112.

GPX3 methylation in bone marrow predicts adverse prognosis and leukemia transformation in myelodysplastic syndrome

Jing‐Dong Zhou, Jiang Lin, Ting‐Juan Zhang, Ji‐Chun Ma, Lei Yang, Xiang‐Mei Wen, Hong Guo, Jing Yang, Zhao‐Qun Deng, Jun Qian

Cancer Med. 2017 Jan; 6(1): 267–274. Published online 2016 Nov 28. doi: 10.1002/cam4.984

PMCID:: PMC5269561

Abstract Article PDF–265K

Select item 452585513.

GPX3 promoter is methylated in chronic myeloid leukemia

Dong-Ming Yao, Jing-Dong Zhou, Ying-Ying Zhang, Lei Yang, Xiang-Mei Wen, Jing Yang, Hong Guo, Qin Chen, Jiang Lin, Jun Qian

Int J Clin Exp Pathol. 2015; 8(6): 6450–6457. Published online 2015 Jun 1.

PMCID:: PMC4525855

Abstract Article PDF–1.5M

Select item 444005414.

Down-regulation of GPX3 is associated with favorable/intermediate karyotypes in de novo acute myeloid leukemia

Jing-Dong Zhou, Xiang-Mei Wen, Ying-Ying Zhang, Lei Yang, Yu-Juan Ma, Ji-Chun Ma, Jing Yang, Hong Guo, Dong-Ming Yao, Jiang Lin, Jun Qian

Int J Clin Exp Pathol. 2015; 8(3): 2384–2391. Published online 2015 Mar 1.

PMCID:: PMC4440054

Abstract Article PDF–689K

Select item 334811515.

A role for GPx3 in activity of normal and leukemia stem cells

Olivier Herault, Kristin J. Hope, Eric Deneault, Nadine Mayotte, Jalila Chagraoui, Brian T. Wilhelm, Sonia Cellot, Martin Sauvageau, Miguel A. Andrade-Navarro, Josée Hébert, Guy Sauvageau

J Exp Med. 2012 May 7; 209(5): 895–901. doi: 10.1084/jem.20102386

PMCID:: PMC3348115

Abstract Article PDF–1.8M

Select item 883221816.

Antioxidative Defense Genes and Brain Structure in Youth Bipolar Disorder

Yi Zou, Kody G Kennedy, Anahit Grigorian, Lisa Fiksenbaum, Natalie Freeman, Clement C Zai, James L Kennedy, Bradley J MacIntosh, Benjamin I Goldstein

Int J Neuropsychopharmacol. 2022 Feb; 25(2): 89–98. Published online 2021 Aug 13. doi: 10.1093/ijnp/pyab056

PMCID:: PMC8832218

Abstract Article PDF–1.2M

Select item 847645117.

Serum selenium, selenoprotein P and glutathione peroxidase 3 as predictors of mortality and recurrence following breast cancer diagnosis: A multicentre cohort study

Kamil Demircan, Ylva Bengtsson, Qian Sun, Annie Brange, Johan Vallon-Christersson, Eddy Rijntjes, Martin Malmberg, Lao H. Saal, Lisa Rydén, Åke Borg, Jonas Manjer, Lutz Schomburg

Redox Biol. 2021 Nov; 47: 102145. Published online 2021 Sep 21. doi: 10.1016/j.redox.2021.102145

PMCID:: PMC8476451

Abstract Article PDF–5.7M

Select item 755960318.

Association between glutathione peroxidase‐3 activity and carotid atherosclerosis in patients with type 2 diabetes mellitus

Ping Ling, Wanying Shan, Guojie Zhai, Chunfang Qiu, Yuan Liu, Yuan Xu, Xiuyan Yang

Brain Behav. 2020 Oct; 10(10): e01773. Published online 2020 Aug 29. doi: 10.1002/brb3.1773

PMCID:: PMC7559603

Abstract Article PDF–396K

Select item 636884919.

Role of GPx3 in PPARγ-induced protection against COPD-associated oxidative stress

Aravind T. Reddy, Sowmya P. Lakshmi, Asoka Banno, Raju C. Reddy

Free Radic Biol Med. Author manuscript; available in PMC 2019 Oct 1.

Published in final edited form as: Free Radic Biol Med. 2018 Oct; 126: 350–357. Published online 2018 Aug 15. doi: 10.1016/j.freeradbiomed.2018.08.014

PMCID:: PMC6368849

Abstract Article PDF–950K

Select item 560698920.

Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis

Beben Benyamin, Ji He, Qiongyi Zhao, Jacob Gratten, Fleur Garton, Paul J. Leo, Zhijun Liu, Marie Mangelsdorf, Ammar Al-Chalabi, Lisa Anderson, Timothy J. Butler, Lu Chen, Xiang-Ding Chen, Katie Cremin, Hong-Weng Deng, Matthew Devine, Janette Edson, Jennifer A. Fifita, Sarah Furlong, Ying-Ying Han, Jessica Harris, Anjali K. Henders, Rosalind L. Jeffree, Zi-Bing Jin, Zhongshan Li, Ting Li, Mengmeng Li, Yong Lin, Xiaolu Liu, Mhairi Marshall, Emily P. McCann, Bryan J. Mowry, Shyuan T. Ngo, Roger Pamphlett, Shu Ran, David C. Reutens, Dominic B. Rowe, Perminder Sachdev, Sonia Shah, Sharon Song, Li-Jun Tan, Lu Tang, Leonard H. van den Berg, Wouter van Rheenen, Jan H. Veldink, Robyn H. Wallace, Lawrie Wheeler, Kelly L. Williams, Jinyu Wu, Xin Wu, Jian Yang, Weihua Yue, Zong-Hong Zhang, Dai Zhang, Peter G. Noakes, Ian P. Blair, Robert D. Henderson, Pamela A. McCombe, Peter M. Visscher, Huji Xu, Perry F. Bartlett, Matthew A. Brown, Naomi R. Wray, Dongsheng Fan

Nat Commun. 2017; 8: 611. Published online 2017 Sep 20. doi: 10.1038/s41467-017-00471-1

PMCID:: PMC5606989

Abstract Article PDF–812K

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PMC Links for Gene (Select 2878) (54)
PMC
PREDICTED: Homo sapiens ENTH domain containing 1 (ENTHD1), transcript variant X5...
PREDICTED: Homo sapiens ENTH domain containing 1 (ENTHD1), transcript variant X5, mRNA
gi|2462583895|ref|XM_054325153.1|

Nucleotide
RecName: Full=Glutathione peroxidase 3; Short=GPx-3; Short=GSHPx-3; AltName: Ful...
RecName: Full=Glutathione peroxidase 3; Short=GPx-3; Short=GSHPx-3; AltName: Full=Extracellular glutathione peroxidase; AltName: Full=Plasma glutathione peroxidase; Short=GPx-P; Short=GSHPx-P; Flags: Precursor
gi|172046796|sp|P22352.2|GPX3_HUMAN

Protein
AXL AXL receptor tyrosine kinase [Homo sapiens]
AXL AXL receptor tyrosine kinase [Homo sapiens]
Gene ID:558

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