PMC Links for Gene (Select 2886) - PMC

Menachem J. Gunzburg, Ketav Kulkarni, Gabrielle M. Watson, Nigus D. Ambaye, Mark P. Del Borgo, Rebecca Brandt, Stephanie C. Pero, Patrick Perlmutter, Matthew C. J. Wilce, Jacqueline A. Wilce

Sci Rep. 2016; 6: 27060. Published online 2016 Jun 3. doi: 10.1038/srep27060

PMCID:: PMC4891710

Abstract Article PDF–1.7M

Select item 46376696.

Grb7 gene amplification and protein expression by FISH and IHC in ovarian cancer

Manman Zeng, Zhu Yang, Xiaoyu Hu, Yi Liu, Xiaotao Yang, Hailong Ran, Yanan Li, Xu Li, Qiubo Yu

Int J Clin Exp Pathol. 2015; 8(9): 11296–11304. Published online 2015 Sep 1.

PMCID:: PMC4637669

Abstract Article PDF–886K

Select item 39364437.

Preparation of crystals for characterizing the Grb7 SH2 domain before and after complex formation with a bicyclic peptide antagonist

Nigus D. Ambaye, Menachem J. Gunzburg, Daouda A. K. Traore, Mark P. Del Borgo, Patrick Perlmutter, Matthew C. J. Wilce, Jacqueline A. Wilce

Acta Crystallogr F Struct Biol Commun. 2014 Feb 1; 70(Pt 2): 182–186. Published online 2014 Jan 21. doi: 10.1107/S2053230X13033414

PMCID:: PMC3936443

Abstract Article PDF–541K

Select item 37584798.

The Intertwining of Structure and Function: Proposed Helix-Swapping of the SH2 Domain of Grb7, A Regulatory Protein Implicated in Cancer Progression and Inflammation

Sally C. Pias, Tabitha A. Peterson, Dennis L. Johnson, Barbara A. Lyons

Crit Rev Immunol. Author manuscript; available in PMC 2013 Aug 30.

Published in final edited form as: Crit Rev Immunol. 2010; 30(3): 299–304. doi: 10.1615/critrevimmunol.v30.i3.70

PMCID:: PMC3758479

Abstract Article PDF–1.0M

Select item 37584749.

Dimerization in the Grb7 Protein

Tabitha A. Peterson, Renee L. Benallie, Andrew M. Bradford, Sally C. Pias, Jaron. Yazzie, Siamee N. Lor, Zachary M. Haulsee, Chad K. Park, Dennis L. Johnson, Larry R. Rohrschneider, Anne. Spuches, Barbara A. Lyons

J Mol Recognit. Author manuscript; available in PMC 2013 Aug 30.

Published in final edited form as: J Mol Recognit. 2012 Aug; 25(8): 427–434. doi: 10.1002/jmr.2205

PMCID:: PMC3758474

Abstract Article PDF–1.6M

Select item 325618810.

Novel Nonphosphorylated Peptides with Conserved Sequences Selectively Bind to Grb7 SH2 Domain with Affinity Comparable to Its Phosphorylated Ligand

Dan Zhang, Chen Shao, Siqi Hu, Sucan Ma, Youhe Gao

PLoS One. 2012; 7(1): e29902. Published online 2012 Jan 11. doi: 10.1371/journal.pone.0029902

PMCID:: PMC3256188

Abstract Article PDF–532K

Select item 299837311.

Preparation and crystallization of the Grb7 SH2 domain in complex with the G7-18NATE nonphosphorylated cyclic inhibitor peptide

Min Y. Yap, Matthew C. J. Wilce, Daniel J. Clayton, Patrick Perlmutter, Marie-Isabel Aguilar, Jacqueline A. Wilce

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Dec 1; 66(Pt 12): 1640–1643. Published online 2010 Nov 26. doi: 10.1107/S1744309110041850

PMCID:: PMC2998373

Abstract Article PDF–202K

Select item 282609712.

Growth factor receptor-bound protein-7 (Grb7) as a prognostic marker and therapeutic target in breast cancer

Y. Nadler, A. M. González, R. L. Camp, D. L. Rimm, H. M. Kluger, Y. Kluger

Ann Oncol. 2010 Mar; 21(3): 466–473. Published online 2009 Aug 28. doi: 10.1093/annonc/mdp346

PMCID:: PMC2826097

Abstract Article PDF–431K

Select item 281486713.

Grb7 Upregulation Is a Molecular Adaptation to HER2 Signaling Inhibition Due to Removal of Akt-Mediated Gene Repression

Alessio Nencioni, Michele Cea, Anna Garuti, Mario Passalacqua, Lizzia Raffaghello, Debora Soncini, Eva Moran, Gabriele Zoppoli, Vito Pistoia, Franco Patrone, Alberto Ballestrero

PLoS One. 2010; 5(2): e9024. Published online 2010 Feb 2. doi: 10.1371/journal.pone.0009024

PMCID:: PMC2814867

Abstract Article PDF–833K

Select item 235994614.

Combination treatment with Grb7 peptide and Doxorubicin or Trastuzumab (Herceptin) results in cooperative cell growth inhibition in breast cancer cells

S C Pero, G S Shukla, M M Cookson, S Flemer, Jr, D N Krag

Br J Cancer. 2007 May 21; 96(10): 1520–1525. Published online 2007 Apr 10. doi: 10.1038/sj.bjc.6603732

PMCID:: PMC2359946

Abstract Article PDF–113K

Select item 225337715.

Backbone nuclear relaxation characteristics and calorimetric investigation of the human Grb7-SH2/erbB2 peptide complex

Monika Ivancic, Anne M. Spuches, Ethan C. Guth, Margaret A. Daugherty, Dean E. Wilcox, Barbara A. Lyons

Protein Sci. 2005 Jun; 14(6): 1556–1569. doi: 10.1110/ps.041102305

PMCID:: PMC2253377

Abstract Article PDF–1.2M

Select item 880995016.

Knockdown of growth factor receptor bound protein 7 suppresses angiogenesis by inhibiting the secretion of vascular endothelial growth factor A in ovarian cancer cells

Qiong Xu, Zequn Liu, Zhi-qin Zhu, Yue Fan, Rui Chen, Xiao-hui Xie, Mi Cheng

Bioengineered. 2021; 12(2): 12179–12190. Published online 2021 Dec 7. doi: 10.1080/21655979.2021.2005225

PMCID:: PMC8809950

Abstract Article PDF–3.1M

Select item 769335617.

GRB7 is an oncogenic driver and potential therapeutic target in oesophageal adenocarcinoma

Jovana R Gotovac, David SH Liu, Michael J Yates, Julia V Milne, Arthi A Macpherson, Kaylene J Simpson, Guy D Eslick, Catherine Mitchell, Cuong P Duong, Wayne A Phillips, Nicholas J Clemons

J Pathol. 2020 Nov; 252(3): 317–329. Published online 2020 Sep 15. doi: 10.1002/path.5528

PMCID:: PMC7693356

Abstract Article PDF–4.9M

Select item 574355818.

Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways

Kangmei Chen, Michelle Xin Liu, Celia Sze-Ling Mak, Mingo Ming-Ho Yung, Thomas Ho-Yin Leung, Dakang Xu, Siew-Fei Ngu, Karen Kar-Loen Chan, Huijuan Yang, Hextan Yuen-Sheung Ngan, David Wai Chan

Theranostics. 2018; 8(2): 423–436. Published online 2018 Jan 1. doi: 10.7150/thno.22377

PMCID:: PMC5743558

Abstract Article PDF–2.5M

Select item 413655219.

Grb7 binds to Hax-1 and undergoes an intramolecular domain association that offers a model for Grb7 regulation

Sharareh Siamakpour-Reihani, Tabitha A. Peterson, Andrew M. Bradford, Haroula J. Argiros, Laura Lowell Haas, Siamee N. Lor, Zachary M. Haulsee, Anne M. Spuches, Dennis L. Johnson, Larry R. Rohrschneider, Charles Brad Shuster, Barbara A. Lyons

J Mol Recognit. Author manuscript; available in PMC 2014 Aug 18.

Published in final edited form as: J Mol Recognit. 2011 Mar-Apr; 24(2): 314–321. doi: 10.1002/jmr.1062