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Select item 89409561.

GIT1 protects against breast cancer growth through negative regulation of Notch

Songbai Zhang, Ayako Miyakawa, Malin Wickström, Cecilia Dyberg, Lauri Louhivuori, Manuel Varas-Godoy, Kati Kemppainen, Shigeaki Kanatani, Dagmara Kaczynska, Ivar Dehnisch Ellström, Lotta Elfman, Pauliina Kronqvist, Heli Repo, Katsuhiko Mikoshiba, Cecilia Sahlgren, John Inge Johnsen, Per Uhlén

Nat Commun. 2022; 13: 1537. Published online 2022 Mar 22. doi: 10.1038/s41467-022-28631-y

PMCID:: PMC8940956

Abstract Article PDF–4.9M

Select item 88062352.

GIT1 overexpression promotes epithelial-mesenchymal transition and predicts poor prognosis in hepatocellular carcinoma

Guifu Wang, Xuesong Bai, Guoqing Jiang, Shengjie Jin, Qian Wang, Aoqing Wang, Rui Peng, Aiwu Ke, Dousheng Bai

Bioengineered. 2021; 12(1): 30–43. Published online 2020 Dec 21. doi: 10.1080/21655979.2020.1855914

PMCID:: PMC8806235

Abstract Article PDF–13M

Select item 63179193.

Alternative RNA splicing of the GIT1 gene is associated with neuroendocrine prostate cancer

Ahn R. Lee, Yu Gan, Ning Xie, Varune R. Ramnarine, Jessica M. Lovnicki, Xuesen Dong

Cancer Sci. 2019 Jan; 110(1): 245–255. Published online 2018 Dec 12. doi: 10.1111/cas.13869

PMCID:: PMC6317919

Abstract Article PDF–893K

Select item 31259654.

GIT1 is a novel MEK1–ERK1/2 scaffold that localizes to focal adhesions

Ning Zhang, Weihua Cai, Guoyong Yin, David J. Nagel, Bradford C. Berk

Cell Biol Int. Author manuscript; available in PMC 2011 Jun 29.

Published in final edited form as: Cell Biol Int. 2009 Dec 16; 34(1): 41–47. Published online 2009 Dec 16. doi: 10.1042/CBI20090016

PMCID:: PMC3125965

Abstract Article PDF–1.6M

Select item 27353515.

GIT1 mediates VEGF-induced podosome formation in endothelial cells: critical role for PLCγ

Jing Wang, Yoji Taba, Jinjiang Pang, Guoyong Yin, Chen Yan, Bradford C. Berk

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2010 Feb 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2009 Feb; 29(2): 202–208. Published online 2008 Nov 20. doi: 10.1161/ATVBAHA.108.174391

PMCID:: PMC2735351

Abstract Article PDF–2.9M

Select item 69062096.

MicroRNA-760 acts as a tumor suppressor in gastric cancer development via inhibiting G-protein-coupled receptor kinase interacting protein-1 transcription

Liang Ge, Yu Wang, Quan-Hong Duan, Song-Shan Liu, Guo-Jing Liu

World J Gastroenterol. 2019 Dec 7; 25(45): 6619–6633. Published online 2019 Dec 7. doi: 10.3748/wjg.v25.i45.6619

PMCID:: PMC6906209

Abstract Article PDF–8.7M

Select item 56075497.

Interaction effects of GIT1 and DRD4 gene variants on continuous performance test variables in patients with ADHD

Hyojin Kim, Johanna Inhyang Kim, Haebin Kim, Jae‐Won Kim, Bung‐Nyun Kim

Brain Behav. 2017 Sep; 7(9): e00785. Published online 2017 Aug 1. doi: 10.1002/brb3.785

PMCID:: PMC5607549

Abstract Article PDF–423K

Select item 43808428.

Methionine Adenosyltransferase 2B–GIT1 Complex Serves as a Scaffold to Regulate Ras/Raf/MEK1/2 Activity in Human Liver and Colon Cancer Cells

Hui Peng, Tony W.H. Li, Heping Yang, Mary P. Moyer, Jose M. Mato, Shelly C. Lu

Am J Pathol. 2015 Apr; 185(4): 1135–1144. doi: 10.1016/j.ajpath.2014.12.016

PMCID:: PMC4380842

Abstract Article PDF–1.7M

Select item 41558089.

MicroRNA-149 targets GIT1 to suppress integrin signaling and breast cancer metastasis

S-H Chan, W-C Huang, J-W Chang, K-J Chang, W-H Kuo, M-Y Wang, K-Y Lin, Y-H Uen, M-F Hou, C-M Lin, T-H Jang, C-W Tu, Y-R Lee, Y-H Lee, M-T Tien, L-H Wang

Oncogene. 2014 Sep 4; 33(36): 4496–4507. Published online 2014 Mar 10. doi: 10.1038/onc.2014.10

PMCID:: PMC4155808

Abstract Article PDF–4.2M

Select item 364222210.

Methionine Adenosyltransferase 2B-GIT1 Interplay Activates MEK1-ERK1/2 to Induce Growth in Human Liver and Colon Cancer

Hui Peng, Lily Dara, Tony W.H. Li, Yuhua Zheng, Heping Yang, Lauda Maria Tomasi, Ivan Tomasi, Pasquale Giordano, Jose M. Mato, Shelly C. Lu

Hepatology. Author manuscript; available in PMC 2014 Jun 1.

Published in final edited form as: Hepatology. 2013 Jun; 57(6): 2299–2313. Published online 2013 May 14. doi: 10.1002/hep.26258

PMCID:: PMC3642222

Abstract Article PDF–2.1M

Select item 343897911.

The Adaptor Protein and Arf GTPase-activating Protein Cat-1/Git-1 Is Required for Cellular Transformation

Sungsoo M. Yoo, Marc A. Antonyak, Richard A. Cerione

J Biol Chem. 2012 Sep 7; 287(37): 31462–31470. Published online 2012 Jul 17. doi: 10.1074/jbc.M112.353615

PMCID:: PMC3438979

Abstract Article PDF–2.6M

Select item 38773612.

GIT1 Activates p21-Activated Kinase through a Mechanism Independent of p21 Binding

Tsui-Han Loo, Yuen-Wai Ng, Louis Lim, Ed Manser

Mol Cell Biol. 2004 May; 24(9): 3849–3859. doi: 10.1128/MCB.24.9.3849-3859.2004

PMCID:: PMC387736

Abstract Article PDF–645K

Select item 346456613.

GIT1 Phosphorylation on Serine 46 by PKD3 Regulates Paxillin Trafficking and Cellular Protrusive Activity

Bettina Huck, Ralf Kemkemer, Mirita Franz-Wachtel, Boris Macek, Angelika Hausser, Monilola A. Olayioye

J Biol Chem. 2012 Oct 5; 287(41): 34604–34613. Published online 2012 Aug 13. doi: 10.1074/jbc.M112.374652

PMCID:: PMC3464566

Abstract Article PDF–1.5M

Select item 299460214.

Induction of Non-Apoptotic Cell Death by Activated Ras Requires Inverse Regulation of Rac1 and Arf6

Haymanti Bhanot, Ashley M. Young, Jean H. Overmeyer, William A. Maltese

Mol Cancer Res. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: Mol Cancer Res. 2010 Oct; 8(10): 1358–1374. Published online 2010 Aug 16. doi: 10.1158/1541-7786.MCR-10-0090

PMCID:: PMC2994602

Abstract Article PDF–3.1M

Select item 236739915.

G protein-coupled receptor kinase 2 positively regulates epithelial cell migration

Petronila Penela, Catalina Ribas, Ivette Aymerich, Niels Eijkelkamp, Olga Barreiro, Cobi J Heijnen, Annemieke Kavelaars, Francisco Sánchez-Madrid, Federico Mayor, Jr

EMBO J. 2008 Apr 23; 27(8): 1206–1218. Published online 2008 Mar 27. doi: 10.1038/emboj.2008.55