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Select item 110720221.

Mfsd7b facilitates choline transport and missense mutations affect choline transport function

Hoa Thi Thuy Ha, Viresh Krishnan Sukumar, Jonathan Wei Bao Chua, Dat T. Nguyen, Toan Q. Nguyen, Lina Hsiu Kim Lim, Amaury Cazenave-Gassiot, Long N. Nguyen

Cell Mol Life Sci. 2024 Dec; 81(1): 3. Published online 2023 Dec 6. doi: 10.1007/s00018-023-05048-4

PMCID:: PMC11072022

Abstract Article PDF–5.5M

Select item 58415642.

A splice-site variant in FLVCR1 produces retinitis pigmentosa without posterior column ataxia

Imran H. Yusuf, Morag E Shanks, Penny Clouston, Robert E. MacLaren

Ophthalmic Genet. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Ophthalmic Genet. 2018 Apr; 39(2): 263–267. Published online 2017 Dec 1. doi: 10.1080/13816810.2017.1408848

PMCID:: PMC5841564

Abstract Article PDF–765K

Select item 55096493.

Increased adipose tissue heme levels and exportation are associated with altered systemic glucose metabolism

José María Moreno-Navarrete, Amaia Rodríguez, Francisco Ortega, Sara Becerril, Mònica Sabater-Masdeu, Jessica Latorre, Wifredo Ricart, Gema Frühbeck, José Manuel Fernández-Real

Sci Rep. 2017; 7: 5305. Published online 2017 Jul 13. doi: 10.1038/s41598-017-05597-2

PMCID:: PMC5509649

Abstract Article PDF–1.5M

Select item 51400524.

Mutations in the Heme Exporter FLVCR1 Cause Sensory Neurodegeneration with Loss of Pain Perception

Deborah Chiabrando, Marco Castori, Maja di Rocco, Martin Ungelenk, Sebastian Gießelmann, Matteo Di Capua, Annalisa Madeo, Paola Grammatico, Sophie Bartsch, Christian A. Hübner, Fiorella Altruda, Lorenzo Silengo, Emanuela Tolosano, Ingo Kurth

PLoS Genet. 2016 Dec; 12(12): e1006461. Published online 2016 Dec 6. doi: 10.1371/journal.pgen.1006461

PMCID:: PMC5140052

Abstract Article PDF–1.7M

Select item 37383845.

Placental Expression of the Heme Transporter, Feline Leukemia Virus Subgroup C Receptor, Is related to Maternal Iron Status in Pregnant Adolescents

Lindsay M. Jaacks, Melissa F. Young, Bridget V. Essley, Thomas J. McNanley, Elizabeth M. Cooper, Eva K. Pressman, Allison W. McIntyre, Mark S. Orlando, Janis L. Abkowitz, Ronnie Guillet, Kimberly O. O'Brien

J Nutr. 2011 Jul; 141(7): 1267–1272. Published online 2011 May 18. doi: 10.3945/jn.110.135798

PMCID:: PMC3738384

Abstract Article PDF–565K

Select item 30790596.

Control of intracellular heme levels: Heme transporters and Heme oxygenases

Anwar A. Khan, John G. Quigley

Biochim Biophys Acta. Author manuscript; available in PMC 2012 May 1.

Published in final edited form as: Biochim Biophys Acta. 2011 May; 1813(5): 668–682. Published online 2011 Jan 14. doi: 10.1016/j.bbamcr.2011.01.008

PMCID:: PMC3079059

Abstract Article PDF–846K

Select item 29789597.

Mutations in FLVCR1 Cause Posterior Column Ataxia and Retinitis Pigmentosa

Anjali M. Rajadhyaksha, Olivier Elemento, Erik G. Puffenberger, Kathryn C. Schierberl, Jenny Z. Xiang, Maria L. Putorti, José Berciano, Chantal Poulin, Bernard Brais, Michel Michaelides, Richard G. Weleber, Joseph J. Higgins

Am J Hum Genet. 2010 Nov 12; 87(5): 643–654. doi: 10.1016/j.ajhg.2010.10.013

PMCID:: PMC2978959

Abstract Article PDF–1.3M

Select item 29287058.

An All-Feline Retroviral Packaging System for Transduction of Human Cells

Raymond T. Doty, Kathleen M. Sabo, Jing Chen, A. Dusty Miller, Janis L. Abkowitz

Hum Gene Ther. 2010 Aug; 21(8): 1019–1027. Published online 2010 Jun 18. doi: 10.1089/hum.2010.032

PMCID:: PMC2928705

Abstract Article PDF–121K

Select item 28644499.

Diamond Blackfan Anemia at the Crossroad between Ribosome Biogenesis and Heme Metabolism

Deborah Chiabrando, Emanuela Tolosano

Adv Hematol. 2010; 2010: 790632. Published online 2010 May 5. doi: 10.1155/2010/790632

PMCID:: PMC2864449

Abstract Article PDF–910K

Select item 11273210.

A Putative Cell Surface Receptor for Anemia-Inducing Feline Leukemia Virus Subgroup C Is a Member of a Transporter Superfamily

Chetankumar S. Tailor, Brian J. Willett, David Kabat

J Virol. 1999 Aug; 73(8): 6500–6505. doi: 10.1128/jvi.73.8.6500-6505.1999

PMCID:: PMC112732

Abstract Article PDF–215K

Select item 1116892311.

Molecular mechanism of choline and ethanolamine transport in humans

Keiken Ri, Tsai-Hsuan Weng, Ainara Claveras Cabezudo, Wiebke Jösting, Yu Zhang, Andre Bazzone, Nancy C. P. Leong, Sonja Welsch, Raymond T. Doty, Gonca Gursu, Tiffany Jia Ying Lim, Sarah Luise Schmidt, Janis L. Abkowitz, Gerhard Hummer, Di Wu, Long N. Nguyen, Schara Safarian

Nature. 2024; 630(8016): 501–508. Published online 2024 May 22. doi: 10.1038/s41586-024-07444-7

PMCID:: PMC11168923

Abstract Article PDF–16M

Select item 136714512.

Comprehensive Mapping of Receptor-Functioning Domains in Feline Leukemia Virus Subgroup C Receptor FLVCR1

Jennifer K. Brown, Claire Fung, Chetankumar S. Tailor

J Virol. 2006 Feb; 80(4): 1742–1751. doi: 10.1128/JVI.80.4.1742-1751.2006

PMCID:: PMC1367145

Abstract Article PDF–505K

Select item 293791413.

Kinetics and Specificity of Feline Leukemia Virus Subgroup C Receptor (FLVCR) Export Function and Its Dependence on Hemopexin

Zhantao Yang, John D. Philips, Raymond T. Doty, Pablo Giraudi, J. Donald Ostrow, Claudio Tiribelli, Ann Smith, Janis L. Abkowitz

J Biol Chem. 2010 Sep 10; 285(37): 28874–28882. Published online 2010 Jul 7. doi: 10.1074/jbc.M110.119131

PMCID:: PMC2937914

Abstract Article PDF–1.0M

Select item 445061714.

The heme exporter Flvcr1 regulates expansion and differentiation of committed erythroid progenitors by controlling intracellular heme accumulation

Sonia Mercurio, Sara Petrillo, Deborah Chiabrando, Zuni Irma Bassi, Dafne Gays, Annalisa Camporeale, Andrei Vacaru, Barbara Miniscalco, Giulio Valperga, Lorenzo Silengo, Fiorella Altruda, Margaret H. Baron, Massimo Mattia Santoro, Emanuela Tolosano

Haematologica. 2015 Jun; 100(6): 720–729. doi: 10.3324/haematol.2014.114488

PMCID:: PMC4450617

Abstract Article PDF–2.5M

Select item 353353415.

The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation

Deborah Chiabrando, Samuele Marro, Sonia Mercurio, Carlotta Giorgi, Sara Petrillo, Francesca Vinchi, Veronica Fiorito, Sharmila Fagoonee, Annalisa Camporeale, Emilia Turco, Giorgio R. Merlo, Lorenzo Silengo, Fiorella Altruda, Paolo Pinton, Emanuela Tolosano

J Clin Invest. 2012 Dec 3; 122(12): 4569–4579. Published online 2012 Nov 26. doi: 10.1172/JCI62422

PMCID:: PMC3533534

Abstract Article PDF–2.7M

Select item 269856716.

Identification of a Feline Leukemia Virus Variant That Can Use THTR1, FLVCR1, and FLVCR2 for Infection

Zvi Shalev, Simon P. Duffy, Karen W. Adema, Rati Prasad, Naveen Hussain, Brian J. Willett, Chetankumar S. Tailor

J Virol. 2009 Jul; 83(13): 6706–6716. Published online 2009 Apr 15. doi: 10.1128/JVI.02317-08

PMCID:: PMC2698567

Abstract Article PDF–1.7M

Select item 1036758217.

Integrative genetic analysis identifies FLVCR1 as a plasma membrane choline transporter in mammals

Timothy C. Kenny, Artem Khan, Yeeun Son, Lishu Yue, Søren Heissel, Anurag Sharma, H. Amalia Pasolli, Yuyang Liu, Eric R. Gamazon, Hanan Alwaseem, Richard K. Hite, KIvanç Birsoy

Cell Metab. Author manuscript; available in PMC 2024 Jun 6.

Published in final edited form as: Cell Metab. 2023 Jun 6; 35(6): 1057–1071.e12. Published online 2023 Apr 25. doi: 10.1016/j.cmet.2023.04.003

PMCID:: PMC10367582

Abstract Article PDF–2.9M

Select item 326015318.

Genetic Mapping and Exome Sequencing Identify Variants Associated with Five Novel Diseases

Erik G. Puffenberger, Robert N. Jinks, Carrie Sougnez, Kristian Cibulskis, Rebecca A. Willert, Nathan P. Achilly, Ryan P. Cassidy, Christopher J. Fiorentini, Kory F. Heiken, Johnny J. Lawrence, Molly H. Mahoney, Christopher J. Miller, Devika T. Nair, Kristin A. Politi, Kimberly N. Worcester, Roni A. Setton, Rosa DiPiazza, Eric A. Sherman, James T. Eastman, Christopher Francklyn, Susan Robey-Bond, Nicholas L. Rider, Stacey Gabriel, D. Holmes Morton, Kevin A. Strauss

PLoS One. 2012; 7(1): e28936. Published online 2012 Jan 17. doi: 10.1371/journal.pone.0028936

PMCID:: PMC3260153

Abstract Article PDF–6.2M

Select item 268887719.

The transcriptome of human CD34⁺ hematopoietic stem-progenitor cells

Yeong C. Kim, Qingfa Wu, Jun Chen, Zhenyu Xuan, Yong-Chul Jung, Michael Q. Zhang, Janet D. Rowley, San Ming Wang

Proc Natl Acad Sci U S A. 2009 May 19; 106(20): 8278–8283. Published online 2009 Apr 30. doi: 10.1073/pnas.0903390106

PMCID:: PMC2688877

Abstract Article PDF–737K

Select item 624272720.

Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development

Meaghan Van Alstyne, Francesco Lotti, Andrea Dal Mas, Estela Area Gomez, Livio Pellizzoni

Biochem Biophys Res Commun. Author manuscript; available in PMC 2019 Nov 30.

Published in final edited form as: Biochem Biophys Res Commun. 2018 Nov 30; 506(3): 463–470. Published online 2018 Oct 22. doi: 10.1016/j.bbrc.2018.10.073

PMCID:: PMC6242727

Abstract Article PDF–910K

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PMC Links for Gene (Select 28982) (40)
PMC
PREDICTED: Homo sapiens FLVCR choline and heme transporter 1 (FLVCR1), transcrip...
PREDICTED: Homo sapiens FLVCR choline and heme transporter 1 (FLVCR1), transcript variant X1, misc_RNA
gi|2462508269|ref|XR_008486008.1|

Nucleotide
PREDICTED: Gorilla gorilla gorilla metal response element binding transcription ...
PREDICTED: Gorilla gorilla gorilla metal response element binding transcription factor 2 (MTF2), transcript variant X2, mRNA
gi|2694984932|ref|XM_019030509.4|

Nucleotide

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