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Items: 14

Select item 108485131.

The epigenetic downregulation of LncGHRLOS mediated by RNA m6A methylase ZCCHC4 promotes colorectal cancer tumorigenesis

Ke Chen, Jingcheng Zhang, Lei Meng, Lingshang Kong, Ming Lu, Zhengguang Wang, Wenbin Wang

J Exp Clin Cancer Res. 2024; 43: 44. Published online 2024 Feb 7. doi: 10.1186/s13046-024-02965-5

Correction in:: J Exp Clin Cancer Res. 2024; 43: 78.

PMCID:: PMC10848513

Abstract Article PDF–3.3M

Select item 92965612.

RNA-binding protein ZCCHC4 promotes human cancer chemoresistance by disrupting DNA-damage-induced apoptosis

Ha Zhu, Kun Chen, Yali Chen, Juan Liu, Xiaomin Zhang, Yumei Zhou, Qiuyan Liu, Bingjing Wang, Taoyong Chen, Xuetao Cao

Signal Transduct Target Ther. 2022; 7: 240. Published online 2022 Jul 20. doi: 10.1038/s41392-022-01033-8

PMCID:: PMC9296561

Abstract Article PDF–9.2M

Select item 69544073.

The human methyltransferase ZCCHC4 catalyses N⁶-methyladenosine modification of 28S ribosomal RNA

Rita Pinto, Cathrine B Vågbø, Magnus E Jakobsson, Yeji Kim, Marijke P Baltissen, Marie-Françoise O’Donohue, Ulises H Guzmán, Jędrzej M Małecki, Jie Wu, Finn Kirpekar, Jesper V Olsen, Pierre-Emmanuel Gleizes, Michiel Vermeulen, Sebastian A Leidel, Geir Slupphaug, Pål Ø Falnes

Nucleic Acids Res. 2020 Jan 24; 48(2): 830–846. Published online 2019 Dec 4. doi: 10.1093/nar/gkz1147

PMCID:: PMC6954407

Abstract Article PDF–2.6M

Select item 68345944.

Structure and regulation of ZCCHC4 in m⁶A-methylation of 28S rRNA

Wendan Ren, Jiuwei Lu, Mengjiang Huang, Linfeng Gao, Dongxu Li, Gang Greg Wang, Jikui Song

Nat Commun. 2019; 10: 5042. Published online 2019 Nov 6. doi: 10.1038/s41467-019-12923-x

PMCID:: PMC6834594

Abstract Article PDF–1.5M

Select item 64634805.

N⁶-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation

Honghui Ma, Xiaoyun Wang, Jiabin Cai, Qing Dai, S. Kundhavai Natchiar, Ruitu Lv, Kai Chen, Zhike Lu, Hao Chen, Yujiang Geno Shi, Fei Lan, Jia Fan, Bruno P. Klaholz, Tao Pan, Yang Shi, Chuan He

Nat Chem Biol. Author manuscript; available in PMC 2020 Jan 1.

Published in final edited form as: Nat Chem Biol. 2019 Jan; 15(1): 88–94. Published online 2018 Dec 10. doi: 10.1038/s41589-018-0184-3

Correction in:: Nat Chem Biol. 2019 Feb 8

PMCID:: PMC6463480

Abstract Article PDF–726K

Select item 67358656.

The human 18S rRNA m⁶A methyltransferase METTL5 is stabilized by TRMT112

Nhan van Tran, Felix G M Ernst, Ben R Hawley, Christiane Zorbas, Nathalie Ulryck, Philipp Hackert, Katherine E Bohnsack, Markus T Bohnsack, Samie R Jaffrey, Marc Graille, Denis L J Lafontaine

Nucleic Acids Res. 2019 Sep 5; 47(15): 7719–7733. Published online 2019 Jul 22. doi: 10.1093/nar/gkz619

PMCID:: PMC6735865

Abstract Article PDF–4.3M

Select item 3109347.

Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells

Qing-Hua Zhang, Min Ye, Xin-Yan Wu, Shuang-Xi Ren, Meng Zhao, Chun-Jun Zhao, Gang Fu, Yu Shen, Hui-Yong Fan, Gang Lu, Ming Zhong, Xiang-Ru Xu, Ze-Guang Han, Ji-Wang Zhang, Jiong Tao, Qiu-Hua Huang, Jun Zhou, Geng-Xi Hu, Jian Gu, Sai-Juan Chen, Zhu Chen

Genome Res. 2000 Oct; 10(10): 1546–1560. doi: 10.1101/gr.140200

PMCID:: PMC310934

Abstract Article PDF–1.3M

Select item 62262258.

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation

Jaewoo Choi, Anita Saraf, Laurence Florens, Michael P. Washburn, Luca Busino

Cell Cycle. 2018; 17(18): 2243–2255. Published online 2018 Sep 25. doi: 10.1080/15384101.2018.1522912

PMCID:: PMC6226225

Abstract Article PDF–1.7M

Select item 100729069.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 910523510.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151