PMC Links for Gene (Select 296849) - PMC

Select item 72748611.

Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis

Lian Tian, Danchen Wu, Asish Dasgupta, Kuang-Hueih Chen, Jeffrey Mewburn, Francois Potus, Patricia A.D. Lima, Zhigang Hong, Yuan-Yuan Zhao, Charles C.T. Hindmarch, Shelby Kutty, Steeve Provencher, Sebastien Bonnet, Gopinath Sutendra, Stephen L. Archer

Circ Res. Author manuscript; available in PMC 2021 Jun 5.

Published in final edited form as: Circ Res. 2020 Jun 5; 126(12): 1723–1745. Published online 2020 Mar 27. doi: 10.1161/CIRCRESAHA.120.316443

PMCID:: PMC7274861

Abstract Article PDF–3.1M

Select item 26613832.

Induction of Pyruvate Dehydrogenase Kinase-3 by Hypoxia-inducible Factor-1 Promotes Metabolic Switch and Drug Resistance

Chun-Wun Lu, Shih-Chieh Lin, Ko-Fan Chen, Yen-Yu Lai, Shaw-Jenq Tsai

J Biol Chem. 2008 Oct 17; 283(42): 28106–28114. doi: 10.1074/jbc.M803508200

PMCID:: PMC2661383

Abstract Article PDF–524K

Select item 11425963.

Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex

Masato Kato, Jacinta L Chuang, Shih-Chia Tso, R Max Wynn, David T Chuang

EMBO J. 2005 May 18; 24(10): 1763–1774. Published online 2005 Apr 28. doi: 10.1038/sj.emboj.7600663

PMCID:: PMC1142596

Abstract Article PDF–479K

Select item 111362534.

Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia, and cancer

T. E. Roche, Y. Hiromasa

Cell Mol Life Sci. 2007 Apr; 64(7-8): 830. Published online 2007 Feb 19. doi: 10.1007/s00018-007-6380-z

PMCID:: PMC11136253

Abstract Article PDF–855K

Select item 12220335.

Regulation of pyruvate dehydrogenase activity through phosphorylation at multiple sites.

E Kolobova, A Tuganova, I Boulatnikov, K M Popov

Biochem J. 2001 Aug 15; 358(Pt 1): 69–77. doi: 10.1042/0264-6021:3580069

PMCID:: PMC1222033

Summary PDF–195K

Select item 27788446.

A mitochondrial protein compendium elucidates complex I disease biology

David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha

Cell. Author manuscript; available in PMC 2009 Nov 18.

Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016

PMCID:: PMC2778844

Abstract Article PDF–1.2M

Select item 1392417.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

Select item 31780598.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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