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Select item 68961771.

NOP53 as A Candidate Modifier Locus for Familial Non-Medullary Thyroid Cancer

Aida Orois, Sudheer K. Gara, Mireia Mora, Irene Halperin, Sandra Martínez, Rocio Alfayate, Electron Kebebew, Josep Oriola

Genes (Basel) 2019 Nov; 10(11): 899. Published online 2019 Nov 7. doi: 10.3390/genes10110899

PMCID:: PMC6896177

Abstract Article PDF–2.5M

Select item 59235022.

Cytoplasmic Translocation of Nucleolar Protein NOP53 Promotes Viral Replication by Suppressing Host Defense

Wen Meng, Shi-Chong Han, Cui-Cui Li, Hui-Jun Dong, Jian-Yu Chang, Hwa-Chain Robert Wang, Xiao-Jia Wang

Viruses. 2018 Apr; 10(4): 208. Published online 2018 Apr 20. doi: 10.3390/v10040208

PMCID:: PMC5923502

Abstract Article PDF–3.8M

Select item 32646353.

Nucleolar Localization of GLTSCR2/PICT-1 Is Mediated by Multiple Unique Nucleolar Localization Sequences

Inna Kalt, Ayelet Levy, Tatyana Borodianskiy-Shteinberg, Ronit Sarid

PLoS One. 2012; 7(1): e30825. Published online 2012 Jan 23. doi: 10.1371/journal.pone.0030825

PMCID:: PMC3264635

Abstract Article PDF–803K

Select item 31572394.

Involvement of GLTSCR2 in the DNA Damage Response

Jee-Youn Kim, Kum-Ok Seok, Yong-Jun Kim, Won Ki Bae, Sun Lee, Jae-Hoon Park

Am J Pathol. 2011 Sep; 179(3): 1257–1264. doi: 10.1016/j.ajpath.2011.05.041

PMCID:: PMC3157239

Abstract Article PDF–2.0M

Select item 44598405.

GLTSCR2 is an upstream negative regulator of nucleophosmin in cervical cancer

Jee-Youn Kim, Young-Eun Cho, Yong-Min An, Sang-Hoon Kim, Yong-Gwan Lee, Jae-Hoon Park, Sun Lee

J Cell Mol Med. 2015 Jun; 19(6): 1245–1252. Published online 2015 Mar 27. doi: 10.1111/jcmm.12474

PMCID:: PMC4459840

Abstract Article PDF–773K

Select item 41102886.

Nucleolar Stress Induces Ubiquitination-independent Proteasomal Degradation of PICT1 Protein

Tomohiko Maehama, Kohichi Kawahara, Miki Nishio, Akira Suzuki, Kentaro Hanada

J Biol Chem. 2014 Jul 25; 289(30): 20802–20812. Published online 2014 Jun 12. doi: 10.1074/jbc.M114.571893

PMCID:: PMC4110288

Abstract Article PDF–1.6M

Select item 37989617.

PICT1 regulates TP53 via RPL11 and is involved in gastric cancer progression

R Uchi, R Kogo, K Kawahara, T Sudo, T Yokobori, H Eguchi, K Sugimachi, T Maehama, M Mori, A Suzuki, S Komune, K Mimori

Br J Cancer. 2013 Oct 15; 109(8): 2199–2206. Published online 2013 Sep 17. doi: 10.1038/bjc.2013.561

PMCID:: PMC3798961

Abstract Article PDF–1.1M

Select item 34384928.

Nucleolar protein GLTSCR2 stabilizes p53 in response to ribosomal stresses

S Lee, J-Y Kim, Y-J Kim, K-O Seok, J-H Kim, Y-J Chang, H-Y Kang, J-H Park

Cell Death Differ. 2012 Oct; 19(10): 1613–1622. Published online 2012 Apr 20. doi: 10.1038/cdd.2012.40

PMCID:: PMC3438492

Abstract Article PDF–711K

Select item 28260649.

GLTSCR2/PICT-1, a Putative Tumor Suppressor Gene Product, Induces the Nucleolar Targeting of the Kaposi's Sarcoma-Associated Herpesvirus KS-Bcl-2 Protein

Inna Kalt, Tatyana Borodianskiy-Shteinberg, Adi Schachor, Ronit Sarid

J Virol. 2010 Mar; 84(6): 2935–2945. Published online 2009 Dec 30. doi: 10.1128/JVI.00757-09

PMCID:: PMC2826064

Abstract Article PDF–2.2M

Select item 163540210.

Critical Role of PICT-1, a Tumor Suppressor Candidate, in Phosphatidylinositol 3,4,5-Trisphosphate Signals and Tumorigenic Transformation

Fumiaki Okahara, Kouichi Itoh, Akira Nakagawara, Makoto Murakami, Yasunori Kanaho, Tomohiko Maehama

Mol Biol Cell. 2006 Nov; 17(11): 4888–4895. doi: 10.1091/mbc.E06-04-0301

PMCID:: PMC1635402

Abstract Article PDF–1.1M

Select item 509995311.

The nucleolar protein GLTSCR2 is required for efficient viral replication

Peng Wang, Wen Meng, Shi-Chong Han, Cui-Cui Li, Xiao-Jun Wang, Xiao-Jia Wang

Sci Rep. 2016; 6: 36226. Published online 2016 Nov 8. doi: 10.1038/srep36226

PMCID:: PMC5099953

Abstract Article PDF–2.1M

Select item 10415812.

A Novel Cellular Protein, p60, Interacting with both Herpes Simplex Virus 1 Regulatory Proteins ICP22 and ICP0 Is Modified in a Cell-Type-Specific Manner and Is Recruited to the Nucleus after Infection

Renato Bruni, Beatrice Fineschi, William O. Ogle, Bernard Roizman

J Virol. 1999 May; 73(5): 3810–3817. doi: 10.1128/jvi.73.5.3810-3817.1999

PMCID:: PMC104158

Abstract Article PDF–827K

Select item 534667413.

PICT-1 triggers a pro-death autophagy through inhibiting rRNA transcription and AKT/mTOR/p70S6K signaling pathway

Hongbo Chen, Yanhong Duo, Bo Hu, Zhiwei Wang, Fang Zhang, Hsiangi Tsai, Jianping Zhang, Lanzhen Zhou, Lijun Wang, Xinyu Wang, Laiqiang Huang

Oncotarget. 2016 Nov 29; 7(48): 78747–78763. Published online 2016 Sep 27. doi: 10.18632/oncotarget.12288

PMCID:: PMC5346674

Abstract Article PDF–9.7M

Select item 395614914.

GLTSCR2/PICT1 links mitochondrial stress and Myc signaling

John C. Yoon, Alvin J. Y. Ling, Meltem Isik, Dong-Young Donna Lee, Michael J. Steinbaugh, Laura M. Sack, Abigail N. Boduch, T. Keith Blackwell, David A. Sinclair, Stephen J. Elledge

Proc Natl Acad Sci U S A. 2014 Mar 11; 111(10): 3781–3786. Published online 2014 Feb 20. doi: 10.1073/pnas.1400705111

PMCID:: PMC3956149

Abstract Article PDF–986K

Select item 536996315.

GLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARF

Sun Lee, Young-Eun Cho, Sang-Hoon Kim, Yong-Jun Kim, Jae-Hoon Park

Oncotarget. 2017 Mar 7; 8(10): 16293–16302. Published online 2016 Apr 28. doi: 10.18632/oncotarget.9957

PMCID:: PMC5369963

Abstract Article PDF–3.0M

Select item 367564916.

Non-erythroid beta spectrin interacting proteins and their effects on spectrin tetramerization

Akin Sevinc, Leslie W. -M. Fung

Cell Mol Biol Lett. 2011 Dec; 16(4): 595. Published online 2011 Aug 24. doi: 10.2478/s11658-011-0025-9

PMCID:: PMC3675649

Summary PDF–999K

Select item 457831217.

Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11

Masato Sasaki, Kohichi Kawahara, Miki Nishio, Koshi Mimori, Ryunosuke Kogo, Koichi Hamada, Bunsho Itoh, Jia Wang, Yukako Komatsu, Yong Ryoul Yang, Hiroki Hikasa, Yasuo Horie, Takayuki Yamashita, Takehiko Kamijo, Yanping Zhang, Yan Zhu, Carol Prives, Toru Nakano, Tak Wah Mak, Takehiko Sasaki, Tomohiko Maehama, Masaki Mori, Akira Suzuki

Nat Med. Author manuscript; available in PMC 2015 Sep 22.

Published in final edited form as: Nat Med. 2011 Aug; 17(8): 944–951. Published online 2011 Jul 31. doi: 10.1038/nm.2392

PMCID:: PMC4578312

Abstract Article PDF–1.6M

Select item 534776618.

PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway

Hongbo Chen, Liqiao Han, Hsiangi Tsai, Zhiwei Wang, Yanping Wu, Yanhong Duo, Wei Cao, Lijun Chen, Zhirong Tan, Ning Xu, Xianzhang Huang, Junhua Zhuang, Laiqiang Huang

Oncotarget. 2016 Dec 13; 7(50): 83241–83257. Published online 2016 Nov 4. doi: 10.18632/oncotarget.13082

PMCID:: PMC5347766

Abstract Article PDF–10M

Select item 380815319.

The 5S RNP Couples p53 Homeostasis to Ribosome Biogenesis and Nucleolar Stress

Katherine E. Sloan, Markus T. Bohnsack, Nicholas J. Watkins

Cell Rep. 2013 Oct 17; 5(1): 237–247. doi: 10.1016/j.celrep.2013.08.049

PMCID:: PMC3808153

Abstract Article PDF–2.1M

Select item 756458220.

The HMGB1-2 Ovarian Cancer Interactome. The Role of HMGB Proteins and Their Interacting Partners MIEN1 and NOP53 in Ovary Cancer and Drug-Response

María Cámara-Quílez, Aida Barreiro-Alonso, Ángel Vizoso-Vázquez, Esther Rodríguez-Belmonte, María Quindós-Varela, Mónica Lamas-Maceiras, María Esperanza Cerdán

Cancers (Basel) 2020 Sep; 12(9): 2435. Published online 2020 Aug 27. doi: 10.3390/cancers12092435

PMCID:: PMC7564582

Abstract Article PDF–2.2M

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