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Select item 111267191.

H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours

Diego Dibitetto, Martin Liptay, Francesca Vivalda, Hülya Dogan, Ewa Gogola, Martín González Fernández, Alexandra Duarte, Jonas A. Schmid, Morgane Decollogny, Paola Francica, Sara Przetocka, Stephen T. Durant, Josep V. Forment, Ismar Klebic, Myriam Siffert, Roebi de Bruijn, Arne N. Kousholt, Nicole A. Marti, Martina Dettwiler, Claus S. Sørensen, Jean-Christophe Tille, Manuela Undurraga, Intidhar Labidi-Galy, Massimo Lopes, Alessandro A. Sartori, Jos Jonkers, Sven Rottenberg

Nat Commun. 2024; 15: 4430. Published online 2024 May 24. doi: 10.1038/s41467-024-48715-1

PMCID:: PMC11126719

Abstract Article PDF–3.1M

Select item 111159342.

γ-radiation-induced γH2AX formation occurs preferentially in actively transcribing euchromatic loci

Raja S. Vasireddy, Tom C. Karagiannis, Assam El-Osta

Cell Mol Life Sci. 2010 Jan; 67(2): 291–294. Published online 2009 Oct 27. doi: 10.1007/s00018-009-0181-5

PMCID:: PMC11115934

Abstract Article PDF–265K

Select item 89221073.

Pyruvate Facilitates FACT‐Mediated γH2AX Loading to Chromatin and Promotes the Radiation Resistance of Glioblastoma

Siyang Wu, Ruixiu Cao, Bangbao Tao, Ping Wu, Chao Peng, Hong Gao, Ji Liang, Weiwei Yang

Adv Sci (Weinh) 2022 Mar; 9(8): 2104055. Published online 2022 Jan 20. doi: 10.1002/advs.202104055

PMCID:: PMC8922107

Abstract Article PDF–12M

Select item 85686134.

Cleavage-embryo genes and transposable elements are regulated by histone variant H2A.X

Kai-yi SUN, Shi-meng GUO, Gui-ping CHENG, Ying YIN, Ximiao HE, Li-quan ZHOU

J Reprod Dev. 2021 Oct; 67(5): 307–312. Published online 2021 Aug 15. doi: 10.1262/jrd.2021-065

PMCID:: PMC8568613

Abstract Article PDF–4.7M

Select item 80762815.

Detection and quantification of γ-H2AX using a dissociation enhanced lanthanide fluorescence immunoassay

Felicite K. Noubissi, Amber A. McBride, Hannah G. Leppert, Larry J. Millet, Xiaofei Wang, Sandra M. Davern

Sci Rep. 2021; 11: 8945. Published online 2021 Apr 26. doi: 10.1038/s41598-021-88296-3

PMCID:: PMC8076281

Abstract Article PDF–2.2M

Select item 78097016.

ADP‐ribosylation of histone variant H2AX promotes base excision repair

Qian Chen, Chunjing Bian, Xin Wang, Xiuhua Liu, Muzaffer Ahmad Kassab, Yonghao Yu, Xiaochun Yu

EMBO J. 2021 Jan 15; 40(2): e104542. Published online 2020 Dec 2. doi: 10.15252/embj.2020104542

PMCID:: PMC7809701

Abstract Article PDF–1.4M

Select item 78070677.

Dual RNA 3’-end processing of H2A.X messenger RNA maintains DNA damage repair throughout the cell cycle

Esther Griesbach, Margarita Schlackow, William F. Marzluff, Nick J. Proudfoot

Nat Commun. 2021; 12: 359. Published online 2021 Jan 13. doi: 10.1038/s41467-020-20520-6

PMCID:: PMC7807067

Abstract Article PDF–4.5M

Select item 75236558.

γH2AX in the S Phase after UV Irradiation Corresponds to DNA Replication and Does Not Report on the Extent of DNA Damage

Shivnarayan Dhuppar, Sitara Roy, Aprotim Mazumder

Mol Cell Biol. 2020 Oct; 40(20): e00328-20. Prepublished online 2020 Aug 10. Published online 2020 Sep 28. doi: 10.1128/MCB.00328-20

PMCID:: PMC7523655

Abstract Article PDF–2.9M

Select item 74681169.

Changes in γH2AX and H4K16ac levels are involved in the biochemical response to a competitive soccer match in adolescent players

Katarzyna Kozioł, Jacek Zebrowski, Gabriela Betlej, Ewelina Bator, Wojciech Czarny, Wojciech Bajorek, Bartłomiej Czarnota, Robert Czaja, Paweł Król, Aleksandra Kwiatkowska

Sci Rep. 2020; 10: 14481. Published online 2020 Sep 2. doi: 10.1038/s41598-020-71436-6

PMCID:: PMC7468116

Abstract Article PDF–3.8M

Select item 724346710.

In vivo analysis of γH2AX+ cells in skeletal muscle from aged and obese humans

Cory M. Dungan, Bailey D. Peck, R. Grace Walton, Zhengyan Huang, Marcas M. Bamman, Philip A. Kern, Charlotte A. Peterson

FASEB J. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: FASEB J. 2020 May; 34(5): 7018–7035. Published online 2020 Apr 4. doi: 10.1096/fj.202000111RR

PMCID:: PMC7243467

Abstract Article PDF–1.7M

Select item 716054211.

Systematic analysis of lysine acetylome and succinylome reveals the correlation between modification of H2A.X complexes and DNA damage response in breast cancer

Xiuli Gao, Hongguang Bao, Likun Liu, Wenbin Zhu, Liping Zhang, Liling Yue

Oncol Rep. 2020 Jun; 43(6): 1819–1830. Published online 2020 Mar 19. doi: 10.3892/or.2020.7554

PMCID:: PMC7160542

Abstract Article PDF–1.3M

Select item 675456712.

Monoubiquitinated γ-H2AX: abundant product and specific biomarker for non-apoptotic DNA double-strand breaks

Michal W. Luczak, Anatoly Zhitkovich

Toxicol Appl Pharmacol. Author manuscript; available in PMC 2019 Sep 21.

Published in final edited form as: Toxicol Appl Pharmacol. 2018 Sep 15; 355: 238–246. Published online 2018 Jul 10. doi: 10.1016/j.taap.2018.07.007

PMCID:: PMC6754567

Abstract Article PDF–1.3M

Select item 612156513.

Using Persistent Homology as a New Approach for Super-Resolution Localization Microscopy Data Analysis and Classification of γH2AX Foci/Clusters

Andreas Hofmann, Matthias Krufczik, Dieter W. Heermann, Michael Hausmann

Int J Mol Sci. 2018 Aug; 19(8): 2263. Published online 2018 Aug 2. doi: 10.3390/ijms19082263

PMCID:: PMC6121565

Abstract Article PDF–2.4M

Select item 611834314.

Effect of mild temperature shift on poly(ADP-ribose) and γH2AX levels in cultured cells

Sachiko Yamashita, Masakazu Tanaka, Teruaki Sato, Chieri Ida, Narumi Ohta, Takashi Hamada, Taichi Uetsuki, Yoshisuke Nishi, Joel Moss, Masanao Miwa

Biochem Biophys Res Commun. Author manuscript; available in PMC 2018 Aug 31.

Published in final edited form as: Biochem Biophys Res Commun. 2016 Aug 5; 476(4): 594–599. Published online 2016 Jun 2. doi: 10.1016/j.bbrc.2016.06.001

PMCID:: PMC6118343

Abstract Article PDF–824K

Select item 610292615.

Expression of oxidized protein tyrosine phosphatase and γH2AX predicts poor survival of gastric carcinoma patients

Usama Khamis Hussein, Ho Sung Park, Jun Sang Bae, Kyoung Min Kim, Yun Jo Chong, Chan Young Kim, Keun Sang Kwon, Myoung Ja Chung, Ho Lee, Myoung Jae Kang, Woo Sung Moon, Kyu Yun Jang

BMC Cancer. 2018; 18: 836. Published online 2018 Aug 20. doi: 10.1186/s12885-018-4752-4

PMCID:: PMC6102926

Abstract Article PDF–2.6M

Select item 572369316.

Residual γH2AX foci induced by low dose x-ray radiation in bone marrow mesenchymal stem cells do not cause accelerated senescence in the progeny of irradiated cells

Margarita Pustovalova, Тatiana A. Astrelina, Anna Grekhova, Natalia Vorobyeva, Anastasia Tsvetkova, Taisia Blokhina, Victoria Nikitina, Yulia Suchkova, Daria Usupzhanova, Vitalyi Brunchukov, Irina Kobzeva, Тatiana Karaseva, Ivan V. Ozerov, Aleksandr Samoylov, Andrey Bushmanov, Sergey Leonov, Evgeny Izumchenko, Alex Zhavoronkov, Dmitry Klokov, Andreyan N. Osipov

Aging (Albany NY) 2017 Nov; 9(11): 2397–2410. Published online 2017 Nov 21. doi: 10.18632/aging.101327

PMCID:: PMC5723693

Abstract Article PDF–4.7M

Select item 542079717.

miR-24-mediated knockdown of H2AX damages mitochondria and the insulin signaling pathway

Jae Hoon Jeong, Young Cheol Kang, Ying Piao, Sora Kang, Youngmi Kim Pak

Exp Mol Med. 2017 Apr; 49(4): e313. Published online 2017 Apr 7. doi: 10.1038/emm.2016.174

PMCID:: PMC5420797

Abstract Article PDF–3.1M

Select item 522653018.

Low level phosphorylation of histone H2AX on serine 139 (γH2AX) is not associated with DNA double-strand breaks

Paulina Rybak, Agnieszka Hoang, Lukasz Bujnowicz, Tytus Bernas, Krzysztof Berniak, Mirosław Zarębski, Zbigniew Darzynkiewicz, Jerzy Dobrucki

Oncotarget. 2016 Aug 2; 7(31): 49574–49587. Published online 2016 Jul 6. doi: 10.18632/oncotarget.10411

PMCID:: PMC5226530

Abstract Article PDF–11M

Select item 513197219.

Loss of H3K9me3 Correlates with ATM Activation and Histone H2AX Phosphorylation Deficiencies in Hutchinson-Gilford Progeria Syndrome

Haoyue Zhang, Linlin Sun, Kun Wang, Di Wu, Mason Trappio, Celeste Witting, Kan Cao

PLoS One. 2016; 11(12): e0167454. Published online 2016 Dec 1. doi: 10.1371/journal.pone.0167454

PMCID:: PMC5131972

Abstract Article PDF–2.5M

Select item 507797220.

Phosphorylation of gH2AX as a novel prognostic biomarker for laryngoesophageal dysfunction-free survival

María José de Miguel-Luken, Manuel Chaves-Conde, Begoña Quintana, Alicia Menoyo, Isabel Tirado, Verónica de Miguel-Luken, Jerónimo Pachón, David Chinchón, Vladimir Suarez, Amancio Carnero

Oncotarget. 2016 May 31; 7(22): 31723–31737. Published online 2016 May 4. doi: 10.18632/oncotarget.9172

PMCID:: PMC5077972

Abstract Article PDF–1.5M

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