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Select item 88651591.

Histone deacetylase HDAC2 regulates microRNA‐125a expression in neuroblastoma

Denghui Liu, Xianglian Tang, Zhao Huang, Jiabing Wen, Yuxiang Zhou

Brain Behav. 2022 Feb; 12(2): e2401. Published online 2022 Jan 21. doi: 10.1002/brb3.2401

PMCID:: PMC8865159

Abstract Article PDF–7.0M

Select item 79592882.

Knock-Down of HDAC2 in Human Induced Pluripotent Stem Cell Derived Neurons Improves Neuronal Mitochondrial Dynamics, Neuronal Maturation and Reduces Amyloid Beta Peptides

Harald Frankowski, Fred Yeboah, Bonnie J. Berry, Chizuru Kinoshita, Michelle Lee, Kira Evitts, Joshua Davis, Yoshito Kinoshita, Richard S. Morrison, Jessica E. Young

Int J Mol Sci. 2021 Mar; 22(5): 2526. Published online 2021 Mar 3. doi: 10.3390/ijms22052526

PMCID:: PMC7959288

Abstract Article PDF–3.8M

Select item 78122523.

HDAC2 promotes the EMT of colorectal cancer cells and via the modular scaffold function of ENSG00000274093.1

Zhi‐Peng Qi, Ayimukedisi Yalikong, Jia‐Wei Zhang, Shi‐Lun Cai, Bing Li, Sun Di, Zhen‑Tao Lv, En‐Pan Xu, Yun‐Shi Zhong, Ping‐Hong Zhou

J Cell Mol Med. 2021 Jan; 25(2): 1190–1197. Published online 2020 Dec 15. doi: 10.1111/jcmm.16186

PMCID:: PMC7812252

Abstract Article PDF–1.4M

Select item 67905634.

HDAC2‐dependent miRNA signature in acute myeloid leukemia

Mariarosaria Conte, Carmela Dell'Aversana, Giulia Sgueglia, Annamaria Carissimo, Lucia Altucci

FEBS Lett. 2019 Sep; 593(18): 2574–2584. Published online 2019 Jul 19. doi: 10.1002/1873-3468.13521

PMCID:: PMC6790563

Abstract Article PDF–462K

Select item 66189225.

Histone Deacetylase 2 Cell Autonomously Suppresses Excitatory and Enhances Inhibitory Synaptic Function in CA1 Pyramidal Neurons

Jesse E. Hanson, Lunbin Deng, David H. Hackos, Shih-Ching Lo, Benjamin E. Lauffer, Pascal Steiner, Qiang Zhou

J Neurosci. 2013 Apr 3; 33(14): 5924–5929. doi: 10.1523/JNEUROSCI.3162-12.2013

PMCID:: PMC6618922

Abstract Article PDF–820K

Select item 64335566.

HDAC2 dysregulation in the nucleus basalis of Meynert during the progression of Alzheimer’s disease

Laura Mahady, Muhammad Nadeem, Michael Malek-Ahmadi, Kewei Chen, Sylvia E. Perez, Elliott J. Mufson

Neuropathol Appl Neurobiol. Author manuscript; available in PMC 2020 Jun 1.

Published in final edited form as: Neuropathol Appl Neurobiol. 2019 Jun; 45(4): 380–397. Published online 2018 Oct 28. doi: 10.1111/nan.12518

PMCID:: PMC6433556

Abstract Article PDF–1.9M

Select item 63551137.

Genome-wide characterization of lncRNAs in acute myeloid leukemia

Lijun Lei, Siyu Xia, Dan Liu, Xiaoqing Li, Jing Feng, Yaqi Zhu, Jun Hu, Linjian Xia, Lieping Guo, Fei Chen, Hui Cheng, Ke Chen, Hanyang Hu, Xiaohua Chen, Feng Li, Shan Zhong, Nupur Mittal, Guohua Yang, Zhijian Qian, Leng Han, Chunjiang He

Brief Bioinform. 2018 Jul; 19(4): 627–635. Published online 2017 Feb 15. doi: 10.1093/bib/bbx007

PMCID:: PMC6355113

Abstract Article PDF–1.4M

Select item 62762568.

HDAC2 depletion promotes osteosarcoma’s stemness both in vitro and in vivo: a study on a putative new target for CSCs directed therapy

Marcella La Noce, Francesca Paino, Luigi Mele, Gianpaolo Papaccio, Tarik Regad, Angela Lombardi, Federica Papaccio, Vincenzo Desiderio, Virginia Tirino

J Exp Clin Cancer Res. 2018; 37: 296. Published online 2018 Dec 3. doi: 10.1186/s13046-018-0978-x

PMCID:: PMC6276256

Abstract Article PDF–6.8M

Select item 62666559.

Rosmarinic Acid, a Component of Rosemary Tea, Induced the Cell Cycle Arrest and Apoptosis through Modulation of HDAC2 Expression in Prostate Cancer Cell Lines

Yin-Gi Jang, Kyung-A Hwang, Kyung-Chul Choi

Nutrients. 2018 Nov; 10(11): 1784. Published online 2018 Nov 16. doi: 10.3390/nu10111784

PMCID:: PMC6266655

Abstract Article PDF–4.3M

Select item 567174310.

Acute Strenuous Exercise Induces an Imbalance on Histone H4 Acetylation/Histone Deacetylase 2 and Increases the Proinflammatory Profile of PBMC of Obese Individuals

Gilson P. Dorneles, Maria Carolina R. Boeira, Lucas L. Schipper, Ivy R. V. Silva, Viviane R. Elsner, Pedro Dal Lago, Alessandra Peres, Pedro R. T. Romão

Oxid Med Cell Longev. 2017; 2017: 1530230. Published online 2017 Oct 19. doi: 10.1155/2017/1530230

PMCID:: PMC5671743

Abstract Article PDF–1011K

Select item 562884711.

CRISPR-mediated HDAC2 disruption identifies two distinct classes of target genes in human cells

Priyanka Somanath, Rachel Herndon Klein, Paul S. Knoepfler

PLoS One. 2017; 12(10): e0185627. Published online 2017 Oct 5. doi: 10.1371/journal.pone.0185627

PMCID:: PMC5628847

Abstract Article PDF–3.2M

Select item 543849012.

Reduced HDAC2 in skeletal muscle of COPD patients

Masako To, Elisabeth B. Swallow, Kenich Akashi, Kosuke Haruki, S Amanda Natanek, Michael I. Polkey, Kazuhiro Ito, Peter J. Barnes

Respir Res. 2017; 18: 99. Published online 2017 May 19. doi: 10.1186/s12931-017-0588-8

PMCID:: PMC5438490

Abstract Article PDF–1.1M

Select item 543673013.

Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia

Frederick A. Schroeder, Tonya M. Gilbert, Ningping Feng, Brendan D. Taillon, Nora D. Volkow, Robert B. Innis, Jacob M. Hooker, Barbara K. Lipska

ACS Chem Neurosci. 2017 Mar 15; 8(3): 662–668. Published online 2016 Nov 28. doi: 10.1021/acschemneuro.6b00372

PMCID:: PMC5436730

Abstract Article PDF–700K

Select item 528635714.

HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma

Tetsuo Kobayashi, Kosuke Nakazono, Mio Tokuda, Yu Mashima, Brian David Dynlacht, Hiroshi Itoh

EMBO Rep. 2017 Feb; 18(2): 334–343. Published online 2016 Dec 27. doi: 10.15252/embr.201541922

PMCID:: PMC5286357

Abstract Article PDF–2.1M

Select item 519011415.

Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer

Samer Alzoubi, Leigh Brody, Sunniyat Rahman, Anne-Laure Mahul-Mellier, Nicolas Mercado, Kazuhiro Ito, Mona El-Bahrawy, Andrew Silver, Alan Boobis, Jimmy D. Bell, Nabil Hajji

Oncotarget. 2016 Jul 12; 7(28): 44505–44521. Published online 2016 Jun 7. doi: 10.18632/oncotarget.9887

PMCID:: PMC5190114

Abstract Article PDF–15M

Select item 482623616.

The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer

Rui Huang, Simon P Langdon, Matthew Tse, Peter Mullen, In Hwa Um, Dana Faratian, David J Harrison

Oncotarget. 2016 Jan 26; 7(4): 4695–4711. Published online 2015 Dec 14. doi: 10.18632/oncotarget.6618

PMCID:: PMC4826236

Abstract Article PDF–5.6M

Select item 461949517.

Lymphocyte senescence in COPD is associated with decreased histone deacetylase 2 expression by pro-inflammatory lymphocytes

Greg Hodge, Hubertus Jersmann, Hai B. Tran, Eugene Roscioli, Mark Holmes, Paul N. Reynolds, Sandra Hodge

Respir Res. 2015; 16: 130. Published online 2015 Oct 24. doi: 10.1186/s12931-015-0287-2

PMCID:: PMC4619495

Abstract Article PDF–1.5M

Select item 435926318.

HDAC2 deregulation in tumorigenesis is causally connected to repression of immune modulation and defense escape

Mariarosaria Conte, Carmela Dell'Aversana, Rosaria Benedetti, Francesca Petraglia, Annamaria Carissimo, Valeria Belsito Petrizzi, Alfonso Maria D'Arco, Ciro Abbondanza, Angela Nebbioso, Lucia Altucci

Oncotarget. 2015 Jan; 6(2): 886–901. Published online 2014 Nov 25. doi: 10.18632/oncotarget.2816

PMCID:: PMC4359263

Abstract Article PDF–2.7M

Select item 415501619.

Antitumor effects in hepatocarcinoma of isoform-selective inhibition of HDAC2

Yun-Han Lee, Daekwan Seo, Kyung-Ju Choi, Jesper B. Andersen, Min-Ah Won, Mitsuteru Kitade, Luis E. Gómez-Quiroz, Adam D. Judge, Jens U. Marquardt, Chiara Raggi, Elizabeth A. Conner, Ian MacLachlan, Valentina M. Factor, Snorri S. Thorgeirsson

Cancer Res. Author manuscript; available in PMC 2015 Sep 1.

Published in final edited form as: Cancer Res. 2014 Sep 1; 74(17): 4752–4761. Published online 2014 Jun 23. doi: 10.1158/0008-5472.CAN-13-3531