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Select item 102270771.

Elucidation of HHEX in pancreatic endoderm differentiation using a human iPSC differentiation model

Ryo Ito, Azuma Kimura, Yurie Hirose, Yu Hatano, Atsushi Mima, Shin-Ichi Mae, Yamato Keidai, Toshihiro Nakamura, Junji Fujikura, Yohei Nishi, Akira Ohta, Taro Toyoda, Nobuya Inagaki, Kenji Osafune

Sci Rep. 2023; 13: 8659. Published online 2023 May 29. doi: 10.1038/s41598-023-35875-1

PMCID:: PMC10227077

Abstract Article PDF–3.3M

Select item 93216662.

Unraveling the Influence of HHEX Risk Polymorphism rs7923837 on Multiple Sclerosis Pathogenesis

Adela González-Jiménez, Pilar López-Cotarelo, Teresa Agudo-Jiménez, Marisa Martínez-Ginés, Jose Manuel García-Domínguez, Elena Urcelay, Laura Espino-Paisán

Int J Mol Sci. 2022 Jul; 23(14): 7956. Published online 2022 Jul 19. doi: 10.3390/ijms23147956

PMCID:: PMC9321666

Abstract Article PDF–1.1M

Select item 72203283.

The association between HHEX single-nucleotide polymorphism rs5015480 and gestational diabetes mellitus: A meta-analysis

Xingjie Wang, Yuanlin Ding, Xinshan Zhang, Jiawei Rao, Haibin Yu, Haiyan Pan

Medicine (Baltimore) 2020 Mar; 99(12): e19478. Published online 2020 Mar 20. doi: 10.1097/MD.0000000000019478

PMCID:: PMC7220328

Abstract Article PDF–771K

Select item 59307564.

Effect of smoking on the association of HHEX (rs5015480) with diabetes among Korean women and heavy smoking men

Jae Woong Sull, Tae Yong Lee, Sun Ha Jee

BMC Med Genet. 2018; 19: 68. Published online 2018 May 2. doi: 10.1186/s12881-018-0582-0

PMCID:: PMC5930756

Abstract Article PDF–563K

Select item 51278405.

HHEX: A Crosstalker between HCMV Infection and Proliferation of VSMCs

Lingfang Li, Meitong Liu, Leitao Kang, Yifan Li, Ziyu Dai, Bing Wang, Shuiping Liu, Liyu Chen, Yurong Tan, Guojun Wu

Front Cell Infect Microbiol. 2016; 6: 169. Published online 2016 Nov 30. doi: 10.3389/fcimb.2016.00169

PMCID:: PMC5127840

Abstract Article PDF–9.0M

Select item 50454326.

Two variants on T2DM susceptible gene HHEX are associated with CRC risk in a Chinese population

Rui Sun, Jian-Ping Liu, Chang Gao, Ying-Ying Xiong, Min Li, Ya-Ping Wang, Yan-Wei Su, Mei Lin, An-Li Jiang, Ling-Fan Xiong, Yan Xie, Jue-Ping Feng

Oncotarget. 2016 May 17; 7(20): 29770–29779. Published online 2016 Apr 20. doi: 10.18632/oncotarget.8865

PMCID:: PMC5045432

Abstract Article PDF–1.4M

Select item 48050447.

Screening of HHEX Mutations in Chinese Children with Thyroid Dysgenesis

Shiguo Liu, Jian Chai, Guohua Zheng, Huichao Li, Deguo Lu, Yinlin Ge

J Clin Res Pediatr Endocrinol. 2016 Mar; 8(1): 21–25. Published online 2016 Mar 1. doi: 10.4274/jcrpe.2456

PMCID:: PMC4805044

Abstract Article PDF–104K

Select item 34995308.

Hematopoietically-Expressed Homeobox Gene Three Widely-Evaluated Polymorphisms and Risk for Diabetes: A Meta-Analysis

Xiaobo Li, Yuqiong Li, Bei Song, Shujie Guo, Shaoli Chu, Nan Jia, Wenquan Niu

PLoS One. 2012; 7(11): e49917. Published online 2012 Nov 15. doi: 10.1371/journal.pone.0049917

PMCID:: PMC3499530

Abstract Article PDF–371K

Select item 34629969.

Dasatinib inhibits leukaemic cell survival by decreasing PRH/Hhex phosphorylation resulting in increased repression of VEGF signalling genes

Peter Noy, Kevin Gaston, Padma-Sheela Jayaraman

Leuk Res. 2012 Nov; 36(11): 1434–1437. doi: 10.1016/j.leukres.2012.07.013

PMCID:: PMC3462996

Abstract Article PDF–470K

Select item 333506810.

The Proline Rich Homeodomain Protein PRH/Hhex Forms Stable Oligomers That Are Highly Resistant to Denaturation

Anshuman Shukla, Nicholas M. Burton, Padma-Sheela Jayaraman, Kevin Gaston

PLoS One. 2012; 7(4): e35984. Published online 2012 Apr 23. doi: 10.1371/journal.pone.0035984

PMCID:: PMC3335068

Abstract Article PDF–1.9M

Select item 885988011.

Integrated single-cell transcriptomics and epigenomics reveals strong germinal center-associated etiology of autoimmune risk loci

Hamish W King, Kristen L Wells, Zohar Shipony, Arwa S Kathiria, Lisa E Wagar, Caleb Lareau, Nara Orban, Robson Capasso, Mark M Davis, Lars M Steinmetz, Louisa K James, William J Greenleaf

Sci Immunol. Author manuscript; available in PMC 2022 Oct 15.

Published in final edited form as: Sci Immunol. 2021 Oct 15; 6(64): eabh3768. Published online 2021 Oct 8. doi: 10.1126/sciimmunol.abh3768

PMCID:: PMC8859880

Abstract Article PDF–3.3M

Select item 396413912.

CDKAL1 and HHEX are associated with type-2 diabetes-related traits among Yup’ik people

Yann C. KLIMENTIDIS, Dominick J. LEMAS, Howard H. WIENER, Diane M. O’BRIEN, Peter J. HAVEL, Kimber L. STANHOPE, Scarlett E. HOPKINS, Hemant K. TIWARI, Bert B. BOYER

J Diabetes. Author manuscript; available in PMC 2015 May 1.

Published in final edited form as: J Diabetes. 2014 May; 6(3): 251–259. Published online 2013 Oct 29. doi: 10.1111/1753-0407.12093

PMCID:: PMC3964139

Abstract Article PDF–99K

Select item 396124613.

HHEX Promotes Hepatic-Lineage Specification through the Negative Regulation of Eomesodermin

Hitoshi Watanabe, Kazuo Takayama, Mitsuru Inamura, Masashi Tachibana, Natsumi Mimura, Kazufumi Katayama, Katsuhisa Tashiro, Yasuhito Nagamoto, Fuminori Sakurai, Kenji Kawabata, Miho Kusuda Furue, Hiroyuki Mizuguchi

PLoS One. 2014; 9(3): e90791. Published online 2014 Mar 20. doi: 10.1371/journal.pone.0090791

PMCID:: PMC3961246

Abstract Article PDF–1.2M

Select item 332363314.

Genetic Variants of IDE-KIF11-HHEX at 10q23.33 Associated with Type 2 Diabetes Risk: A Fine-Mapping Study in Chinese Population

Yun Qian, Feng Lu, Meihua Dong, Yudi Lin, Huizhang Li, Jian Chen, Chong Shen, Guangfu Jin, Zhibin Hu, Hongbing Shen

PLoS One. 2012; 7(4): e35060. Published online 2012 Apr 10. doi: 10.1371/journal.pone.0035060

PMCID:: PMC3323633

Abstract Article PDF–101K

Select item 311707015.

Replication of the association between variants in the IDE-KIF11-HHEX harboring region on chromosome 10q and plasma amyloid β levels in Alzheimer’s disease

Christiane Reitz, Rong Cheng, Nicole Schupf, Joseph H. Lee, Pankaj D. Mehta, Ekaterina Rogaeva, Peter St George-Hyslop, Richard Mayeux

Neurobiol Aging. Author manuscript; available in PMC 2013 Jan 1.

Published in final edited form as: Neurobiol Aging. 2012 Jan; 33(1): 199.e13–199.e17. Published online 2010 Aug 17. doi: 10.1016/j.neurobiolaging.2010.07.005

PMCID:: PMC3117070

Abstract Article PDF–991K

Select item 311005616.

Heterogeneity of genetic associations of CDKAL1 and HHEX with susceptibility of type 2 diabetes mellitus by gender

Hyunju Ryoo, Jiyoung Woo, Younyoung Kim, Chaeyoung Lee

Eur J Hum Genet. 2011 Jun; 19(6): 672–675. Published online 2011 Feb 2. doi: 10.1038/ejhg.2011.6

PMCID:: PMC3110056

Abstract Article PDF–196K

Select item 291962917.

No association between FTO or HHEX andendometrial cancer risk

Mia M. Gaudet, Hannah P. Yang, Jesus Gonzalez Bosquet, Catherine S. Healey, Shahana Ahmed, Alison M. Dunning, Doug F. Easton, Amanda B. Spurdle, Kaltin Ferguson, Tracy O’Mara, ANECS Group, Diether Lambrechts, Evelyn Despierre, Ignace Vergote, Frederic Amant, James V. Lacey, Jr., Jola Lissowska, Beata Peplonska, Louise A. Brinton, Stephen Chanock, Montserrat Garcia-Closas

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2011 Feb 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 Aug; 19(8): 2106–2109. Published online 2010 Jul 20. doi: 10.1158/1055-9965.EPI-10-0515

PMCID:: PMC2919629

Abstract Article PDF–839K

Select item 286358018.

PRH/Hhex Controls Cell Survival through Coordinate Transcriptional Regulation of Vascular Endothelial Growth Factor Signaling

Peter Noy, Hannah Williams, Anyaporn Sawasdichai, Kevin Gaston, Padma-Sheela Jayaraman

Mol Cell Biol. 2010 May; 30(9): 2120–2134. Published online 2010 Feb 22. doi: 10.1128/MCB.01511-09

PMCID:: PMC2863580

Abstract Article PDF–2.0M

Select item 282661819.

Polymorphisms of TCF7L2 and HHEX genes in Chinese women with polycystic ovary syndrome

Pei Xu, Yena Che, Yunxia Cao, XiaoKe Wu, Haixiang Sun, Fengjing Liang, Jing Sun, Lu Ke, Long Yi, Yong Wang

J Assist Reprod Genet. 2010 Jan; 27(1): 23–28. Published online 2009 Dec 30. doi: 10.1007/s10815-009-9377-8

PMCID:: PMC2826618

Abstract Article PDF–121K

Select item 33440020.

Identification of a novel vertebrate homeobox gene expressed in haematopoietic cells.

M R Crompton, T J Bartlett, A D MacGregor, G Manfioletti, E Buratti, V Giancotti, G H Goodwin

Nucleic Acids Res. 1992 Nov 11; 20(21): 5661–5667. doi: 10.1093/nar/20.21.5661

PMCID:: PMC334400

Summary Page Browse PDF–1.6M

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