PMC Links for Gene (Select 3157) - PMC

Claire A. Walsh, Nina Akrap, Elena Garre, Ylva Magnusson, Hannah Harrison, Daniel Andersson, Emma Jonasson, Svanheidur Rafnsdottir, Hani Choudhry, Francesca Buffa, Jiannis Ragoussis, Anders Ståhlberg, Adrian Harris, Göran Landberg

PLoS One. 2020; 15(7): e0236187. Published online 2020 Jul 21. doi: 10.1371/journal.pone.0236187

PMCID:: PMC7373278

Abstract Article PDF–2.4M

Select item 72222874.

A new genetic locus for antipsychotic-induced weight gain: A genome-wide study of first-episode psychosis patients using amisulpride (from the OPTiMiSE cohort)

Sophie E ter Hark, Stéphane Jamain, Dick Schijven, Bochao D Lin, Mark K Bakker, Anne Boland-Auge, Jean-François Deleuze, Réjane Troudet, Anil K Malhotra, Sinan Gülöksüz, Christiaan H Vinkers, Bjørn H Ebdrup, René S Kahn, Marion Leboyer, Jurjen J Luykx

J Psychopharmacol. 2020 May; 34(5): 524–531. Published online 2020 Mar 4. doi: 10.1177/0269881120907972

PMCID:: PMC7222287

Abstract Article PDF–715K

Select item 3232565.

Localization of the gene encoding 3-hydroxy-3-methylglutaryl-coenzyme A synthase to human chromosome 5.

S Leonard, D Arbogast, D Geyer, C Jones, M Sinensky

Proc Natl Acad Sci U S A. 1986 Apr; 83(7): 2187–2189. doi: 10.1073/pnas.83.7.2187

PMCID:: PMC323256

Summary Page Browse PDF–775K

Select item 3045416.

Optional exon in the 5'-untranslated region of 3-hydroxy-3-methylglutaryl coenzyme A synthase gene: conserved sequence and splicing pattern in humans and hamsters.

G Gil, J R Smith, J L Goldstein, M S Brown

Proc Natl Acad Sci U S A. 1987 Apr; 84(7): 1863–1866. doi: 10.1073/pnas.84.7.1863

PMCID:: PMC304541

Summary Page Browse PDF–934K

Select item 99110787.

VIM-AS1 promotes proliferation and drives enzalutamide resistance in prostate cancer via IGF2BP2-mediated HMGCS1 mRNA stabilization

Sheng-Jia Shi, Dong-Hui Han, Jing-Liang Zhang, Yu Li, An-Gang Yang, Rui Zhang

Int J Oncol. 2023 Mar; 62(3): 34. Published online 2023 Jan 30. doi: 10.3892/ijo.2023.5482

PMCID:: PMC9911078

Abstract Article PDF–2.9M

Select item 62905468.

The isomiR-140-3p-regulated mevalonic acid pathway as a potential target for prevention of triple negative breast cancer

Anjana Bhardwaj, Harpreet Singh, Celestine Marie Trinidad, Constance T. Albarracin, Kelly K. Hunt, Isabelle Bedrosian

Breast Cancer Res. 2018; 20: 150. Published online 2018 Dec 11. doi: 10.1186/s13058-018-1074-z

PMCID:: PMC6290546

Abstract Article PDF–7.2M

Select item 54732209.

HMG-CoA synthase 1 is a synthetic lethal partner of BRAF^V600E in human cancers

Liang Zhao, Jun Fan, Siyuan Xia, Yaozhu Pan, Shuangping Liu, Guoqing Qian, Zhiyu Qian, Hee-Bum Kang, Jack L. Arbiser, Brian P. Pollack, Ragini R. Kudchadkar, David H. Lawson, Michael Rossi, Omar Abdel-Wahab, Taha Merghoub, Hanna J. Khoury, Fadlo R. Khuri, Lawrence H. Boise, Sagar Lonial, Fangping Chen, Jing Chen, Ruiting Lin

J Biol Chem. 2017 Jun 16; 292(24): 10142–10152. Published online 2017 May 3. doi: 10.1074/jbc.M117.788778

PMCID:: PMC5473220

Abstract Article PDF–3.5M

Select item 5400610.

Rat mitochondrial and cytosolic 3-hydroxy-3-methylglutaryl-CoA synthases are encoded by two different genes.

J Ayté, G Gil-Gómez, D Haro, P F Marrero, F G Hegardt

Proc Natl Acad Sci U S A. 1990 May; 87(10): 3874–3878. doi: 10.1073/pnas.87.10.3874

PMCID:: PMC54006

Summary Page Browse PDF–1.3M

Select item 1100568911.

CSN6‐SPOP‐HMGCS1 Axis Promotes Hepatocellular Carcinoma Progression via YAP1 Activation

Kai Li, Jiayu Zhang, Haiwen Lyu, Jinneng Yang, Wenxia Wei, Yuzhi Wang, Haidan Luo, Yijing Zhang, Xin Jiang, Hairong Yi, Mengan Wang, Caiyun Zhang, Kang Wu, Lishi Xiao, Weijie Wen, Hui Xu, Guolin Li, Yunle Wan, Fang Yang, Runxiang Yang, Xinhui Fu, Baifu Qin, Zhongguo Zhou, Haipeng Zhang, Mong‐Hong Lee

Adv Sci (Weinh) 2024 Apr; 11(14): 2306827. Published online 2024 Feb 2. doi: 10.1002/advs.202306827

PMCID:: PMC11005689

Abstract Article PDF–9.1M

Select item 844237612.

circHMGCS1–016 reshapes immune environment by sponging miR-1236-3p to regulate CD73 and GAL-8 expression in intrahepatic cholangiocarcinoma

Ya-Ping Xu, Ze-Ning Dong, Si-Wei Wang, Yi-Min Zheng, Chi Zhang, Ying-Qun Zhou, Yu-Jie Zhao, Yan Zhao, Feng Wang, Rui Peng, Mao-Chun Tang, Dou-sheng Bai, Xiao-Yong Huang, Chuan-Yong Guo

J Exp Clin Cancer Res. 2021; 40: 290. Published online 2021 Sep 15. doi: 10.1186/s13046-021-02095-2

PMCID:: PMC8442376

Abstract Article PDF–5.9M

Select item 834837613.

TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination

Wan Yun Ho, Jer-Cherng Chang, Kenneth Lim, Amaury Cazenave-Gassiot, Aivi T. Nguyen, Juat Chin Foo, Sneha Muralidharan, Ashley Viera-Ortiz, Sarah J.M. Ong, Jin Hui Hor, Ira Agrawal, Shawn Hoon, Olubankole Aladesuyi Arogundade, Maria J. Rodriguez, Su Min Lim, Seung Hyun Kim, John Ravits, Shi-Yan Ng, Markus R. Wenk, Edward B. Lee, Greg Tucker-Kellogg, Shuo-Chien Ling

J Cell Biol. 2021 Sep 6; 220(9): e201910213. Published online 2021 Aug 4. doi: 10.1083/jcb.201910213

PMCID:: PMC8348376

Abstract Article PDF–11M

Select item 797189014.

JMJD6 negatively regulates cytosolic RNA induced antiviral signaling by recruiting RNF5 to promote activated IRF3 K48 ubiquitination

Wei Zhang, Qi Wang, Fan Yang, Zixiang Zhu, Yueyue Duan, Yang Yang, Weijun Cao, Keshan Zhang, Junwu Ma, Xiangtao Liu, Haixue Zheng

PLoS Pathog. 2021 Mar; 17(3): e1009366. Published online 2021 Mar 8. doi: 10.1371/journal.ppat.1009366

PMCID:: PMC7971890

Abstract Article PDF–3.3M

Select item 795192715.

A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models

Natalya A. Ortolano, Alejandra I. Romero-Morales, Megan L. Rasmussen, Caroline Bodnya, Leigh A. Kline, Piyush Joshi, Jon P. Connelly, Kristie L. Rose, Shondra M. Pruett-Miller, Vivian Gama

PLoS One. 2021; 16(3): e0248000. Published online 2021 Mar 11. doi: 10.1371/journal.pone.0248000

PMCID:: PMC7951927

Abstract Article PDF–3.8M

Select item 565328816.

Intrinsic BET inhibitor resistance in prostate cancer caused by SPOP mutation-mediated BET protein stabilization

Pingzhao Zhang, Dejie Wang, Yu Zhao, Shancheng Ren, Kun Gao, Zhenqing Ye, Shangqian Wang, Chun-Wu Pan, Yasheng Zhu, Yuqian Yan, Yinhui Yang, Di Wu, Yundong He, Jun Zhang, Daru Lu, Xiuping Liu, Long Yu, Shimin Zhao, Yao Li, Dong Lin, Yuzhuo Wang, Liguo Wang, Yu Chen, Yinghao Sun, Chenji Wang, Haojie Huang

Nat Med. Author manuscript; available in PMC 2018 Feb 14.

Published in final edited form as: Nat Med. 2017 Sep; 23(9): 1055–1062. Published online 2017 Aug 14. doi: 10.1038/nm.4379

PMCID:: PMC5653288

Abstract Article PDF–1.7M

Select item 981605917.

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1

Dongbao Li, Yuhong Wang, Chao Dong, Tao Chen, Anqi Dong, Jiayu Ren, Weikang Li, Gege Shu, Jiaoyang Yang, Wenhao Shen, Lei Qin, Lin Hu, Jin Zhou

Oncogene. 2023; 42(2): 83–98. Published online 2022 Nov 12. doi: 10.1038/s41388-022-02537-x

PMCID:: PMC9816059

Abstract Article PDF–7.6M

Select item 975347118.

LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF‐κB to the nucleus

Zhixiao Wu, Lena A Berlemann, Verian Bader, Dominik A Sehr, Eva Dawin, Alberto Covallero, Jens Meschede, Lena Angersbach, Cathrin Showkat, Jonas B Michaelis, Christian Münch, Bettina Rieger, Dmitry Namgaladze, Maria Georgina Herrera, Fabienne C Fiesel, Wolfdieter Springer, Marta Mendes, Jennifer Stepien, Katalin Barkovits, Katrin Marcus, Albert Sickmann, Gunnar Dittmar, Karin B Busch, Dietmar Riedel, Marisa Brini, Jörg Tatzelt, Tito Cali, Konstanze F Winklhofer

EMBO J. 2022 Dec; 41(24): e112006. Published online 2022 Nov 18. doi: 10.15252/embj.2022112006

PMCID:: PMC9753471

Abstract Article PDF–4.3M

Select item 247469619.

Polymorphisms in the Estrogen Receptor 1 and Vitamin C and Matrix Metalloproteinase Gene Families Are Associated with Susceptibility to Lymphoma

Christine F. Skibola, Paige M. Bracci, Eran Halperin, Alexandra Nieters, Alan Hubbard, Randi A. Paynter, Danica R. Skibola, Luz Agana, Nikolaus Becker, Patrick Tressler, Matthew S. Forrest, Sriram Sankararaman, Lucia Conde, Elizabeth A. Holly, Martyn T. Smith

PLoS One. 2008; 3(7): e2816. Published online 2008 Jul 30. doi: 10.1371/journal.pone.0002816

PMCID:: PMC2474696

Abstract Article PDF–172K

Select item 955026620.

Spike S1 domain interactome in non-pulmonary systems: A role beyond the receptor recognition

Ilaria Iacobucci, Vittoria Monaco, Luisa Canè, Francesca Bibbò, Valentina Cioffi, Flora Cozzolino, Alfredo Guarino, Massimo Zollo, Maria Monti

Front Mol Biosci. 2022; 9: 975570. Published online 2022 Sep 26. doi: 10.3389/fmolb.2022.975570

PMCID:: PMC9550266

Abstract Article PDF–2.5M

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