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Select item 106462551.

Uncovering the role of FOXA2 in the Development of Human Serotonin Neurons

Ting Xu, Lining Cao, Jinjin Duan, Yingqi Li, You Li, Zhangsen Hu, Shuanqing Li, Meihui Zhang, Guanhao Wang, Fei Guo, Jianfeng Lu

Adv Sci (Weinh) 2023 Nov; 10(32): 2303884. Published online 2023 Sep 7. doi: 10.1002/advs.202303884

PMCID:: PMC10646255

Abstract Article PDF–11M

Select item 104785032.

Genome-wide differential expression profiling of long non-coding RNAs in FOXA2 knockout iPSC-derived pancreatic cells

Ahmed K. Elsayed, Nehad M. Alajez, Essam M. Abdelalim

Cell Commun Signal. 2023; 21: 229. Published online 2023 Sep 5. doi: 10.1186/s12964-023-01212-2

PMCID:: PMC10478503

Abstract Article PDF–12M

Select item 103916293.

FOXA2 controls the anti-oxidant response in FH-deficient cells

Connor Rogerson, Marco Sciacovelli, Lucas A. Maddalena, Andromachi Pouikli, Marc Segarra-Mondejar, Lorea Valcarcel-Jimenez, Christina Schmidt, Ming Yang, Elena Ivanova, Joshua Kent, Ariane Mora, Danya Cheeseman, Jason S. Carroll, Gavin Kelsey, Christian Frezza

Cell Rep. 2023 Jul 25; 42(7): 112751. Published online 2023 Jul 4. doi: 10.1016/j.celrep.2023.112751

PMCID:: PMC10391629

Abstract Article

Select item 93815454.

Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes

Maryam Aghadi, Ramy Elgendy, Essam M. Abdelalim

Cell Death Dis. 2022 Aug; 13(8): 713. Published online 2022 Aug 16. doi: 10.1038/s41419-022-05158-0

PMCID:: PMC9381545

Abstract Article PDF–8.8M

Select item 84566675.

FoXA2 promotes esophageal squamous cell carcinoma progression by ZEB2 activation

Hanjing Gao, Zheng Yan, Haiyan Sun, Yanfang Chen

World J Surg Oncol. 2021; 19: 286. Published online 2021 Sep 22. doi: 10.1186/s12957-021-02358-4

PMCID:: PMC8456667

Abstract Article PDF–3.4M

Select item 78759046.

The pioneer and differentiation factor FOXA2 is a key driver of yolk‐sac tumour formation and a new biomarker for paediatric and adult yolk‐sac tumours

Wasco Wruck, Felix Bremmer, Mara Kotthoff, Alexander Fichtner, Margaretha A. Skowron, Stefan Schönberger, Gabriele Calaminus, Christian Vokuhl, David Pfister, Axel Heidenreich, Peter Albers, James Adjaye, Daniel Nettersheim

J Cell Mol Med. 2021 Feb; 25(3): 1394–1405. Published online 2021 Jan 14. doi: 10.1111/jcmm.16222

PMCID:: PMC7875904

Abstract Article PDF–2.1M

Select item 78392777.

Correlation Between High Expression of FOXA2 and Improved Overall Survival in Ovarian Cancer Patients

Hui Shang, Lingyun Shi, Xuena Jiang, Peng Zhou, Yongqing Wei

Med Sci Monit. 2021; 27: e928763-1–e928763-10. Prepublished online 2021 Jan 9. Published online 2021 Jan 23. doi: 10.12659/MSM.928763

PMCID:: PMC7839277

Abstract Article PDF–2.4M

Select item 67920208.

FOXA2 controls the cis‐regulatory networks of pancreatic cancer cells in a differentiation grade‐specific manner

Marta Milan, Chiara Balestrieri, Gabriele Alfarano, Sara Polletti, Elena Prosperini, Paola Spaggiari, Alessandro Zerbi, Giuseppe R Diaferia, Gioacchino Natoli

EMBO J. 2019 Oct 15; 38(20): e102161. Published online 2019 Sep 17. doi: 10.15252/embj.2019102161

PMCID:: PMC6792020

Abstract Article PDF–6.0M

Select item 66368629.

FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation

Kihyun Lee, Hyunwoo Cho, Robert W. Rickert, Qing V. Li, Julian Pulecio, Christina S. Leslie, Danwei Huangfu

Cell Rep. Author manuscript; available in PMC 2019 Jul 17.

Published in final edited form as: Cell Rep. 2019 Jul 9; 28(2): 382–393.e7. doi: 10.1016/j.celrep.2019.06.034

PMCID:: PMC6636862

Abstract Article PDF–3.0M

Select item 659387510.

Integrative analysis of the forkhead box A2 (FOXA2) cistrome for the human endometrium

Andrew M. Kelleher, Susanta K. Behura, Gregory W. Burns, Steven L. Young, Francesco J. DeMayo, Thomas E. Spencer

FASEB J. 2019 Jul; 33(7): 8543–8554. Published online 2019 Apr 5. doi: 10.1096/fj.201900013R

PMCID:: PMC6593875

Abstract Article

Select item 633017711.

FOXA2 is a Sensitive and Specific marker for Small Cell Neuroendocrine Carcinoma of the Prostate

Jung Wook Park, John K. Lee, Owen N. Witte, Jiaoti Huang

Mod Pathol. Author manuscript; available in PMC 2019 Jan 13.

Published in final edited form as: Mod Pathol. 2017 Sep; 30(9): 1262–1272. Published online 2017 Jun 16. doi: 10.1038/modpathol.2017.44

PMCID:: PMC6330177

Abstract Article PDF–2.6M

Select item 623571512.

Functional characterization of recurrent FOXA2 mutations seen in endometrial cancers

Robert Neff, Craig M. Rush, Blair Smith, Floor J. Backes, David E. Cohn, Paul J. Goodfellow

Int J Cancer. Author manuscript; available in PMC 2019 Dec 1.

Published in final edited form as: Int J Cancer. 2018 Dec 1; 143(11): 2955–2961. Published online 2018 Sep 29. doi: 10.1002/ijc.31784

PMCID:: PMC6235715

Abstract Article PDF–522K

Select item 573501013.

The FOXA2 transcription factor is frequently somatically mutated in uterine carcinosarcomas and carcinomas

Matthieu Le Gallo, Meghan L. Rudd, Mary Ellen Urick, Nancy F. Hansen, NIH Intramural Sequencing Center (NISC) Comparative Sequencing Program, Maria J. Merino, David G. Mutch, Paul J. Goodfellow, James C. Mullikin, Daphne W. Bell

Cancer. Author manuscript; available in PMC 2019 Jan 1.

Published in final edited form as: Cancer. 2018 Jan 1; 124(1): 65–73. Published online 2017 Sep 21. doi: 10.1002/cncr.30971

PMCID:: PMC5735010

Abstract Article PDF–1.1M

Select item 570786914.

Autophagy maintains the stemness of ovarian cancer stem cells by FOXA2.

Qiaohua Peng, Jiale Qin, Yanan Zhang, Xiaodong Cheng, Xinyu Wang, Weiguo Lu, Xing Xie, Songfa Zhang

J Exp Clin Cancer Res. 2017; 36: 171. Published online 2017 Nov 29. doi: 10.1186/s13046-017-0644-8

PMCID:: PMC5707869

Abstract Article PDF–5.5M

Select item 561489815.

Structure of the forkhead domain of FOXA2 bound to a complete DNA consensus site

Jun Li, Ana Carolina Dantas Machado, Ming Guo, Jared M. Sagendorf, Zhan Zhou, Longying Jiang, Xiaojuan Chen, Daichao Wu, Lingzhi Qu, Zhuchu Chen, Lin Chen, Remo Rohs, Yongheng Chen

Biochemistry. Author manuscript; available in PMC 2018 Jul 25.

Published in final edited form as: Biochemistry. 2017 Jul 25; 56(29): 3745–3753. Published online 2017 Jul 11. doi: 10.1021/acs.biochem.7b00211

PMCID:: PMC5614898

Abstract Article PDF–1.4M

Select item 525619916.

Triple Staining Including FOXA2 Identifies Stem Cell Lineages Undergoing Hepatic and Biliary Differentiation in Cirrhotic Human Liver

Charles E. Rogler, Remon Bebawee, Joe Matarlo, Joseph Locker, Nicole Pattamanuch, Sanjeev Gupta, Leslie E. Rogler

J Histochem Cytochem. 2017 Jan; 65(1): 33–46. Published online 2016 Nov 22. doi: 10.1369/0022155416675153

PMCID:: PMC5256199

Abstract Article PDF–2.0M

Select item 507766217.

The mutational spectrum of FOXA2 in endometrioid endometrial cancer points to a tumor suppressor role

B Smith, R Neff, DE Cohn, FJ Backes, AA Suarez, DG Mutch, CM Rush, CJ Walker, PJ Goodfellow

Gynecol Oncol. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: Gynecol Oncol. 2016 Nov; 143(2): 398–405. Published online 2016 Aug 15. doi: 10.1016/j.ygyno.2016.08.237

PMCID:: PMC5077662

Abstract Article PDF–1002K

Select item 500528518.

Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer

Christina Vorvis, Maria Hatziapostolou, Swapna Mahurkar-Joshi, Marina Koutsioumpa, Jennifer Williams, Timothy R. Donahue, George A. Poultsides, Guido Eibl, Dimitrios Iliopoulos

Am J Physiol Gastrointest Liver Physiol. 2016 Jun 1; 310(11): G1124–G1137. Published online 2016 May 5. doi: 10.1152/ajpgi.00035.2016

PMCID:: PMC5005285

Abstract Article

Select item 449152719.

FOXA2 regulates a network of genes involved in critical functions of human intestinal epithelial cells

Nehal Gosalia, Rui Yang, Jenny L. Kerschner, Ann Harris

Physiol Genomics. 2015 Jul; 47(7): 290–297. Published online 2015 Apr 28. doi: 10.1152/physiolgenomics.00024.2015

PMCID:: PMC4491527

Abstract Article

Select item 447751320.

Heterozygous Deletion of FOXA2 Segregates with Disease in a Family with Heterotaxy, Panhypopituitarism, and Biliary Atresia

Ellen A. Tsai, Christopher M. Grochowski, Alexandra M. Falsey, Ramakrishnan Rajagopalan, Danielle Wendel, Marcella Devoto, Ian D. Krantz, Kathleen M. Loomes, Nancy B. Spinner

Hum Mutat. Author manuscript; available in PMC 2016 Jun 1.

Published in final edited form as: Hum Mutat. 2015 Jun; 36(6): 631–637. Published online 2015 Apr 21. doi: 10.1002/humu.22786