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Select item 108053851.

A deregulated HOX gene axis confers an epigenetic vulnerability in KRAS-mutant lung cancers

Stephanie L. Guerra, Ophélia Maertens, Ryan Kuzmickas, Thomas De Raedt, Richard O. Adeyemi, Caroline J. Guild, Shawna Guillemette, Amanda J. Redig, Emily S. Chambers, Man Xu, Hong Tiv, Sandro Santagata, Pasi A. Jänne, Steve Elledge, Karen Cichowski

Cancer Cell. Author manuscript; available in PMC 2024 Jan 23.

Published in final edited form as: Cancer Cell. 2020 May 11; 37(5): 705–719.e6. Published online 2020 Apr 2. doi: 10.1016/j.ccell.2020.03.004

PMCID:: PMC10805385

Abstract Article PDF–2.6M

Select item 107814532.

Pan-cancer analysis of homeodomain-containing gene C10 and its carcinogenesis in lung adenocarcinoma

Xiangyuan Tan, Zhanzhan Li, Huayan Xie, Jiarong Chen, Jian Xiao, Yaofeng Zhi, Haixin Mo, Yanming Huang, Aibin Liu

Aging (Albany NY) 2023 Dec 31; 15(24): 15243–15266. Published online 2023 Dec 27. doi: 10.18632/aging.205348

PMCID:: PMC10781453

Abstract Article PDF–5.8M

Select item 88059243.

Homeodomain-containing gene 10 contributed to breast cancer malignant behaviors by activating Interleukin-6/Janus kinase 2/Signal transducer and activator of transcription 3 pathway

Jun Shen, Meng Wang, Fan Li, Huanhuan Yan, Jun Zhou

Bioengineered. 2022; 13(1): 1335–1345. Published online 2022 Jan 5. doi: 10.1080/21655979.2021.2016088

PMCID:: PMC8805924

Abstract Article PDF–4.1M

Select item 42778624.

Epigenetic reprogramming of HOXC10 in endocrine-resistant breast cancer

Thushangi N. Pathiraja, Shweta Nayak, Yuanxin Xi, Shiming Jiang, Jason P. Garee, Dean P. Edwards, Adrian V. Lee, Jian Chen, Martin J. Shea, Richard J. Santen, Frank Gannon, Sara Kangaspeska, Jaroslav Jelinek, Jean-Pierre J. Issa, Jennifer K. Richer, Anthony Elias, Marie McIlroy, Leonie Young, Nancy E. Davidson, Rachel Schiff, Wei Li, Steffi Oesterreich

Sci Transl Med. Author manuscript; available in PMC 2014 Dec 28.

Published in final edited form as: Sci Transl Med. 2014 Mar 26; 6(229): 229ra41. doi: 10.1126/scitranslmed.3008326

PMCID:: PMC4277862

Abstract Article PDF–3.4M

Select item 84563445.

Transcription factor HOXC10 activates the expression of MTFR2 to regulate the proliferation, invasion and migration of colorectal cancer cells

Ying Xie, Ran Chen, Liujia Yan, Zhangjun Jia, Guangshu Liang, Qin Wang

Mol Med Rep. 2021 Nov; 24(5): 797. Published online 2021 Sep 14. doi: 10.3892/mmr.2021.12437

PMCID:: PMC8456344

Abstract Article PDF–13M

Select item 70690846.

Interleukin 1β-mediated HOXC10 Overexpression Promotes Hepatocellular Carcinoma Metastasis by Upregulating PDPK1 and VASP

Yunzhi Dang, Jie Chen, Weibo Feng, Chenyang Qiao, Weili Han, Yongzhan Nie, Kaichun Wu, Daiming Fan, Limin Xia

Theranostics. 2020; 10(8): 3833–3848. Published online 2020 Feb 19. doi: 10.7150/thno.41712

PMCID:: PMC7069084

Abstract Article PDF–3.8M

Select item 65490787.

HOXC10 overexpression promotes cell proliferation and migration in gastric cancer

Jina Kim, Dong-Hyuck Bae, Jong Hwan Kim, Kyu-Sang Song, Yong Sung Kim, Seon-Young Kim

Oncol Rep. 2019 Jul; 42(1): 202–212. Published online 2019 May 17. doi: 10.3892/or.2019.7164

PMCID:: PMC6549078

Abstract Article PDF–1.3M

Select item 1656108.

Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression

Davide Gabellini, Ivan N. Colaluca, Hartmut C. Vodermaier, Giuseppe Biamonti, Mauro Giacca, Arturo Falaschi, Silvano Riva, Fiorenzo A. Peverali

EMBO J. 2003 Jul 15; 22(14): 3715–3724. doi: 10.1093/emboj/cdg340

PMCID:: PMC165610

Abstract Article PDF–319K

Select item 107346669.

m⁶A-modified HOXC10 promotes HNSCC progression via co-activation of ADAM17/EGFR and Wnt/β-catenin signaling

Yujuan Zhou, Qiang Huang, Chunping Wu, Ye Xu, Yang Guo, Xiaohui Yuan, Chengzhi Xu, Liang Zhou

Int J Oncol. 2024 Feb; 64(2): 10. Published online 2023 Dec 6. doi: 10.3892/ijo.2023.5598

PMCID:: PMC10734666

Abstract Article PDF–13M

Select item 836383810.

The lncRNA HMS recruits RNA-binding protein HuR to stabilize the 3′-UTR of HOXC10 mRNA

Priyanka Priyanka, Madhur Sharma, Sanjeev Das, Sandeep Saxena

J Biol Chem. 2021 Aug; 297(2): 100997. Published online 2021 Jul 22. doi: 10.1016/j.jbc.2021.100997

PMCID:: PMC8363838

Abstract Article PDF–3.8M

Select item 621706111.

Overexpression of HOXC10 promotes angiogenesis in human glioma via interaction with PRMT5 and upregulation of VEGFA expression

Zhanyao Tan, Kun Chen, Wenjiao Wu, Yanqing Zhou, Jinrong Zhu, Geyan Wu, Lixue Cao, Xin Zhang, Hongyu Guan, Yi Yang, Wei Zhang, Jun Li

Theranostics. 2018; 8(18): 5143–5158. Published online 2018 Oct 6. doi: 10.7150/thno.27310

PMCID:: PMC6217061

Abstract Article PDF–3.2M

Select item 533655712.

HOXC10 suppresses browning of white adipose tissues

Yvonne Ng, Shi-Xiong Tan, Sook Yoong Chia, Hwee Yim Angeline Tan, Sin Yee Gun, Lei Sun, Wanjin Hong, Weiping Han

Exp Mol Med. 2017 Feb; 49(2): e292. Published online 2017 Feb 10. doi: 10.1038/emm.2016.144

PMCID:: PMC5336557

Abstract Article PDF–2.7M

Select item 447536113.

Anterior migration of lateral plate mesodermal cells during embryogenesis of the pufferfishTakifugu niphobles: insight into the rostral positioning of pelvic fins

Mikiko Tanaka, Reiko Yu, Daisuke Kurokawa

J Anat. 2015 Jul; 227(1): 81–88. Published online 2015 May 28. doi: 10.1111/joa.12324

PMCID:: PMC4475361

Abstract Article PDF–1.8M

Select item 38708314.

Cognate homeo-box loci mapped on homologous human and mouse chromosomes.

M Rabin, A Ferguson-Smith, C P Hart, F H Ruddle

Proc Natl Acad Sci U S A. 1986 Dec; 83(23): 9104–9108. doi: 10.1073/pnas.83.23.9104

PMCID:: PMC387083

Summary Page Browse PDF–1.0M

Select item 33530815.

The human HOX gene family.

D Acampora, M D'Esposito, A Faiella, M Pannese, E Migliaccio, F Morelli, A Stornaiuolo, V Nigro, A Simeone, E Boncinelli

Nucleic Acids Res. 1989 Dec 25; 17(24): 10385–10402. doi: 10.1093/nar/17.24.10385

PMCID:: PMC335308

Summary Page Browse PDF–1.6M

Select item 470210316.

The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety

Sang Jun Han, Khurshida Begum, Charles E. Foulds, Ross A. Hamilton, Suzanna Bailey, Anna Malovannaya, Doug Chan, Jun Qin, Bert W. O’Malley

Mol Pharmacol. 2016 Jan; 89(1): 14–26. Published online 2016 Jan. doi: 10.1124/mol.115.100925

PMCID:: PMC4702103

Abstract Article PDF–1.6M

Select item 754388617.

SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses

Abhik K. Banerjee, Mario R. Blanco, Emily A. Bruce, Drew D. Honson, Linlin M. Chen, Amy Chow, Prashant Bhat, Noah Ollikainen, Sofia A. Quinodoz, Colin Loney, Jasmine Thai, Zachary D. Miller, Aaron E. Lin, Madaline M. Schmidt, Douglas G. Stewart, Daniel Goldfarb, Giuditta De Lorenzo, Suzannah J. Rihn, Rebecca M. Voorhees, Jason W. Botten, Devdoot Majumdar, Mitchell Guttman

Cell. 2020 Nov 25; 183(5): 1325–1339.e21. doi: 10.1016/j.cell.2020.10.004

PMCID:: PMC7543886

Abstract Article

Select item 800904818.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 642009719.

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination in sister chromatids

Kyosuke Nakamura, Giulia Saredi, Jordan R. Becker, Benjamin M. Foster, Nhuong V. Nguyen, Tracey Beyer, Laura C. Cesa, Peter A. Faull, Saulius Lukauskas, Thomas Frimurer, J. Ross Chapman, Till Bartke, Anja Groth

Nat Cell Biol. Author manuscript; available in PMC 2019 Aug 25.

Published in final edited form as: Nat Cell Biol. 2019 Mar; 21(3): 311–318. Published online 2019 Feb 25. doi: 10.1038/s41556-019-0282-9

PMCID:: PMC6420097

Article PDF–1.7M

Select item 567858120.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

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