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Select item 107744231.

Understanding the molecular mechanism of pathogenic variants of BIR2 domain in XIAP-deficient inflammatory bowel disease

Juhwan Lee, Kyoung Mi Sim, Mooseok Kang, Hyun Ju Oh, Ho Jung Choi, Yeong Eun Kim, Chan-Gi Pack, Kyunggon Kim, Kyung Mo Kim, Seak Hee Oh, Inki Kim, Iksoo Chang

Sci Rep. 2024; 14: 853. Published online 2024 Jan 9. doi: 10.1038/s41598-023-50932-5

PMCID:: PMC10774423

Article PDF–2.2M

Select item 105012172.

Ehrlichia Notch signaling induction promotes XIAP stability and inhibits apoptosis

LaNisha L. Patterson, Caitlan D. Byerly, Regina Solomon, Nicholas Pittner, Duc Cuong Bui, Jignesh Patel, Jere W. McBride

Infect Immun. 2023 Sep; 91(9): e00002-23. Published online 2023 Aug 18. doi: 10.1128/iai.00002-23

PMCID:: PMC10501217

Article PDF–2.3M

Select item 97909863.

X-linked inhibitor of apoptosis protein (XIAP) predicts disease-free survival in BRAFV600E mutant papillary thyroid carcinoma in middle eastern patients

Sandeep Kumar Parvathareddy, Abdul K. Siraj, Rong Bu, Kaleem Iqbal, Maha Al-Rasheed, Wael Al-Haqawi, Padmanaban Annaiyappanaidu, Nabil Siraj, Saeeda O. Ahmed, Saif S. Al-Sobhi, Fouad Al-Dayel, Khawla S. Al-Kuraya

Front Endocrinol (Lausanne) 2022; 13: 1054882. Published online 2022 Dec 12. doi: 10.3389/fendo.2022.1054882

PMCID:: PMC9790986

Article PDF–568K

Select item 77245654.

XIAP Regulation by MNK Links MAPK and NFκB Signaling to Determine an Aggressive Breast Cancer Phenotype

Myron K. Evans, Michael C. Brown, Joseph Geradts, Xuhui Bao, Timothy J. Robinson, Mohit Kumar Jolly, Peter B. Vermeulen, Gregory M. Palmer, Matthias Gromeier, Herbert Levine, Michael A. Morse, Steven J. Van Laere, Gayathri R. Devi

Cancer Res. Author manuscript; available in PMC 2020 Dec 9.

Published in final edited form as: Cancer Res. 2018 Apr 1; 78(7): 1726–1738. Published online 2018 Jan 19. doi: 10.1158/0008-5472.CAN-17-1667

PMCID:: PMC7724565

Article PDF–2.0M

Select item 76929595.

XIAP’s Profile in Human Cancer

Huailu Tu, Max Costa

Biomolecules. 2020 Nov; 10(11): 1493. Published online 2020 Oct 29. doi: 10.3390/biom10111493

PMCID:: PMC7692959

Article PDF–1.1M

Select item 74560716.

In-cell destabilization of a homodimeric protein complex detected by DEER spectroscopy

Yin Yang, Shen-Na Chen, Feng Yang, Xia-Yan Li, Akiva Feintuch, Xun-Cheng Su, Daniella Goldfarb

Proc Natl Acad Sci U S A. 2020 Aug 25; 117(34): 20566–20575. Published online 2020 Aug 11. doi: 10.1073/pnas.2005779117

PMCID:: PMC7456071

Article PDF–1.2M

Select item 73978247.

Regulation of Cell Death and Immunity by XIAP

Philipp J. Jost, Domagoj Vucic

Cold Spring Harb Perspect Biol. 2020 Aug; 12(8): a036426. doi: 10.1101/cshperspect.a036426

PMCID:: PMC7397824

Article PDF–821K

Select item 57800758.

XIAP underlies apoptosis resistance of renal cell carcinoma cells

Wen Zheng Yang, Haijiang Zhou, Yong Yan

Mol Med Rep. 2018 Jan; 17(1): 125–130. Published online 2017 Oct 27. doi: 10.3892/mmr.2017.7925

PMCID:: PMC5780075

Article PDF–989K

Select item 55945049.

XIAP over-expression is an independent poor prognostic marker in Middle Eastern breast cancer and can be targeted to induce efficient apoptosis

Azhar R. Hussain, Abdul Khalid Siraj, Maqbool Ahmed, Rong Bu, Poyil Pratheeshkumar, Alanood M. Alrashed, Zeeshan Qadri, Dahish Ajarim, Fouad Al-Dayel, Shaham Beg, Khawla S. Al-Kuraya

BMC Cancer. 2017; 17: 640. Published online 2017 Sep 11. doi: 10.1186/s12885-017-3627-4

PMCID:: PMC5594504

Article PDF–4.0M

Select item 481618510.

X-linked inhibitor of apoptosis protein mediates tumor cell resistance to antibody-dependent cellular cytotoxicity

M K Evans, S J Sauer, S Nath, T J Robinson, M A Morse, G R Devi

Cell Death Dis. 2016 Jan; 7(1): e2073. Published online 2016 Jan 28. doi: 10.1038/cddis.2015.412

PMCID:: PMC4816185

Article PDF–1.5M

Select item 457260111.

Cell-permeable intrinsic cellular inhibitors of apoptosis protect and rescue intestinal epithelial cells from radiation-induced cell death

Shiori Matsuzaki-Horibuchi, Takeshi Yasuda, Nagako Sakaguchi, Yoshihiro Yamaguchi, Makoto Akashi

J Radiat Res. 2015 Jan; 56(1): 100–113. Published online 2014 Oct 30. doi: 10.1093/jrr/rru094

PMCID:: PMC4572601

Article PDF–875K

Select item 448090712.

High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancer

L. Flanagan, J. Kehoe, J. Fay, O. Bacon, A.U. Lindner, E.W. Kay, J. Deasy, D.A. McNamara, J.H.M. Prehn

Radiat Oncol. 2015; 10: 131. Published online 2015 Jun 13. doi: 10.1186/s13014-015-0437-1

PMCID:: PMC4480907

Article PDF–1.2M

Select item 423887413.

A mutation in X-linked inhibitor of apoptosis (G466X) leads to memory inflation of Epstein–Barr virus-specific T cells

E Lopez-Granados, M Stacey, A-K Kienzler, S Sierro, C B Willberg, C P Fox, S Rigaud, H M Long, A D Hislop, A B Rickinson, S Patel, S Latour, P Klenerman, H Chapel

Clin Exp Immunol. 2014 Dec; 178(3): 470–482. Published online 2014 Nov 7. doi: 10.1111/cei.12427

PMCID:: PMC4238874

Article PDF–871K

Select item 408989214.

Cisplatin Resistance in an Ovarian Carcinoma Is Associated With a Defect in Programmed Cell Death Control Through XIAP Regulation

Abdellah Mansouri, Qingxiu Zhang, Lon D. Ridgway, Ling Tian, Francois-Xavier Claret

Oncol Res. Author manuscript; available in PMC 2014 Jul 9.

Published in final edited form as: Oncol Res. 2003; 13(0): 399–404. doi: 10.3727/096504003108748410

PMCID:: PMC4089892

Article PDF–348K

Select item 405606315.

X-chromosome-linked inhibitor of apoptosis as a key factor for chemoresistance in clear cell carcinoma of the ovary

M Miyamoto, M Takano, K Iwaya, N Shinomiya, M Kato, T Aoyama, N Sasaki, T Goto, A Suzuki, J Hitrata, K Furuya

Br J Cancer. 2014 Jun 10; 110(12): 2881–2886. Published online 2014 May 22. doi: 10.1038/bjc.2014.255

PMCID:: PMC4056063

Article PDF–385K

Select item 400459116.

Translational and posttranslational regulation of XIAP by eIF2α and ATF4 promotes ER stress–induced cell death during the unfolded protein response

Nobuhiko Hiramatsu, Carissa Messah, Jaeseok Han, Matthew M. LaVail, Randal J. Kaufman, Jonathan H. Lin

Mol Biol Cell. 2014 May 1; 25(9): 1411–1420. doi: 10.1091/mbc.E13-11-0664

PMCID:: PMC4004591

Article PDF–2.9M

Select item 394600417.

XIAP Antagonist Embelin Inhibited Proliferation of Cholangiocarcinoma Cells

Cody J. Wehrkamp, Ashley R. Gutwein, Sathish Kumar Natarajan, Mary Anne Phillippi, Justin L. Mott

PLoS One. 2014; 9(3): e90238. Published online 2014 Mar 6. doi: 10.1371/journal.pone.0090238

PMCID:: PMC3946004

Article PDF–1.0M

Select item 388768818.

Jolkinolide B from Euphorbia fischeriana Steud Induces Apoptosis in Human Leukemic U937 Cells through PI3K/Akt and XIAP Pathways

Jia-He Wang, Yi-Jun Zhou, Xue Bai, Ping He

Mol Cells. 2011 Nov 30; 32(5): 451–457. doi: 10.1007/s10059-011-0137-0

PMCID:: PMC3887688

Article PDF–578K

Select item 376013119.

The structure of XIAP BIR2: understanding the selectivity of the BIR domains

Christine Lukacs, Charles Belunis, Robert Crowther, Waleed Danho, Lin Gao, Barry Goggin, Cheryl A. Janson, Shirley Li, Stacy Remiszewski, Andrew Schutt, Manish K. Thakur, Saroj K. Singh, Srinivasan Swaminathan, Rajat Pandey, Rajiv Tyagi, Ramachandraiah Gosu, Ajith V. Kamath, Andreas Kuglstatter

Acta Crystallogr D Biol Crystallogr. 2013 Sep 1; 69(Pt 9): 1717–1725. Published online 2013 Aug 15. doi: 10.1107/S0907444913016284