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Items: 1 to 20 of 25

1.
Salivary Antimicrobial Peptide Histatin-5 Does Not Display Zn(II)-Dependent or -Independent Activity against Streptococci
Louisa J. Stewart, YoungJin Hong, Isabel R. Holmes, Samantha J. Firth, Yasmin Ahmed, Janet Quinn, Yazmin Santos, Steven L. Cobb, Nicholas S. Jakubovics, Karrera Y. Djoko
ACS Infect Dis. 2023 Mar 10; 9(3): 631–642. Published online 2023 Feb 24. doi: 10.1021/acsinfecdis.2c00578
PMCID:
PMC10012264
AbstractArticlePDF–4.0M
2.
Histatin 5 variant reduces Candida albicans biofilm viability and inhibits biofilm formation
Parisa Moghaddam-Taaheri, Jesse A. Leissa, Haleigh B. Eppler, Christopher M. Jewell, Amy J. Karlsson
Fungal Genet Biol. Author manuscript; available in PMC 2022 Apr 1.
Published in final edited form as: Fungal Genet Biol. 2021 Apr; 149: 103529. Published online 2021 Feb 14. doi: 10.1016/j.fgb.2021.103529
PMCID:
PMC7940551
AbstractArticlePDF–1.1M
3.
Specific Histidine Residues Confer Histatin Peptides with Copper-Dependent Activity against Candida albicans
Steven E. Conklin, Emma C. Bridgman, Qiang Su, Pamela Riggs-Gelasco, Kathryn L. Haas, Katherine J. Franz
Biochemistry. Author manuscript; available in PMC 2018 Aug 15.
Published in final edited form as: Biochemistry. 2017 Aug 15; 56(32): 4244–4255. Published online 2017 Aug 1. doi: 10.1021/acs.biochem.7b00348
PMCID:
PMC5937946
AbstractArticlePDF–2.4M
4.
How Does It Kill?: Understanding the Candidacidal Mechanism of Salivary Histatin 5
Sumant Puri, Mira Edgerton
Eukaryot Cell. 2014 Aug; 13(8): 958–964. doi: 10.1128/EC.00095-14
PMCID:
PMC4135785
AbstractArticlePDF–840K
5.
Salivary histatin 5 internalization by translocation, but not endocytosis, is required for fungicidal activity in Candida albicans
Woong Sik Jang, Jashanjot Singh Bajwa, Jianing N Sun, Mira Edgerton
Mol Microbiol. 2010 Jul; 77(2): 354–370. Published online 2010 Jun 11. doi: 10.1111/j.1365-2958.2010.07210.x
PMCID:
PMC2909388
AbstractArticlePDF–2.4M
6.
The P-113 Fragment of Histatin 5 Requires a Specific Peptide Sequence for Intracellular Translocation in Candida albicans, Which Is Independent of Cell Wall Binding
Woong Sik Jang, Xuewei Serene Li, Jianing N. Sun, Mira Edgerton
Antimicrob Agents Chemother. 2008 Feb; 52(2): 497–504. Published online 2007 Nov 12. doi: 10.1128/AAC.01199-07
PMCID:
PMC2224728
AbstractArticlePDF–623K
7.
Candidacidal activity of recombinant human salivary histatin-5 and variants.
H Tsai, P A Raj, L A Bobek
Infect Immun. 1996 Dec; 64(12): 5000–5007. doi: 10.1128/iai.64.12.5000-5007.1996
PMCID:
PMC174480
SummaryPDF–298K
8.
Human Salivary Histatin 5 Causes Disordered Volume Regulation and Cell Cycle Arrest in Candida albicans
Didi Baev, Xuewei S. Li, Jin Dong, Peter Keng, Mira Edgerton
Infect Immun. 2002 Sep; 70(9): 4777–4784. doi: 10.1128/IAI.70.9.4777-4784.2002
PMCID:
PMC128240
AbstractArticlePDF–265K
9.
The HTN3-MSANTD3 Fusion Gene Defines a Subset of Acinic Cell Carcinoma of the Salivary Gland
Simon Andreasen, Sushama Varma, Nicholas Barasch, Lester D.R. Thompson, Markku Miettinen, Lisa Rooper, Edward B. Stelow, Tina K. Agander, Raja R. Seethala, Simion I. Chiosea, Preben Homøe, Irene Wessel, Stine R. Larsen, Daiva Erentaite, Justin A. Bishop, Benedicte P. Ulhøi, Katalin Kiss, Linea C. Melchior, Jonathan R. Pollack, Robert B. West
Am J Surg Pathol. Author manuscript; available in PMC 2021 Jun 10.
Published in final edited form as: Am J Surg Pathol. 2019 Apr; 43(4): 489–496. doi: 10.1097/PAS.0000000000001200
PMCID:
PMC8191383
AbstractArticlePDF–2.5M
10.
Salivary Histatin 1 and 2 Are Targeted to Mitochondria and Endoplasmic Reticulum in Human Cells
Dandan Ma, Wei Sun, Kamran Nazmi, Enno C. I. Veerman, Floris J. Bikker, Richard T. Jaspers, Jan G. M. Bolscher, Gang Wu
Cells. 2020 Apr; 9(4): 795. Published online 2020 Mar 26. doi: 10.3390/cells9040795
PMCID:
PMC7226139
AbstractArticlePDF–7.5M
11.
Cooperation of Salivary Protein Histatin 3 with Heat Shock Cognate Protein 70 Relative to the G1/S Transition in Human Gingival Fibroblasts
Yasuhiro Imamura, Yoshihisa Fujigaki, Yuriko Oomori, Syuhei Usui, Pao-Li Wang
J Biol Chem. 2009 May 22; 284(21): 14316–14325. doi: 10.1074/jbc.M807278200
PMCID:
PMC2682880
AbstractArticlePDF–655K
12.
Localization of the genes for histatins to human chromosome 4q13 and tissue distribution of the mRNAs.
J C vanderSpek, H E Wyandt, J C Skare, A Milunsky, F G Oppenheim, R F Troxler
Am J Hum Genet. 1989 Sep; 45(3): 381–387.
PMCID:
PMC1683406
SummaryPage BrowsePDF–1.3M
13.
The assessment of sIgA, histatin-5, and lactoperoxidase levels in saliva of adolescents with dental caries
Agnieszka Gornowicz, Grażyna Tokajuk, Anna Bielawska, Elżbieta Maciorkowska, Robert Jabłoński, Anna Wójcicka, Krzysztof Bielawski
Med Sci Monit. 2014; 20: 1095–1100. Published online 2014 Jun 29. doi: 10.12659/MSM.890468
PMCID:
PMC4087079
AbstractArticlePDF–328K
14.
Histatin 5 Uptake by Candida albicans Utilizes Polyamine Transporters Dur3 and Dur31 Proteins
Rohitashw Kumar, Sonia Chadha, Darpan Saraswat, Jashanjot Singh Bajwa, Rui A. Li, Heather R. Conti, Mira Edgerton
J Biol Chem. 2011 Dec 23; 286(51): 43748–43758. Published online 2011 Oct 27. doi: 10.1074/jbc.M111.311175
PMCID:
PMC3243549
AbstractArticlePDF–1.0M
15.
Uptake of the antifungal cationic peptide Histatin 5 by Candida albicans Ssa2p requires binding to non-conventional sites within the ATPase domain
Jianing N Sun, Wansheng Li, Woong Sik Jang, Namrata Nayyar, Mark D Sutton, Mira Edgerton
Mol Microbiol. 2008 Dec; 70(5): 1246–1260. Published online 2008 Oct 20. doi: 10.1111/j.1365-2958.2008.06480.x
PMCID:
PMC2643122
AbstractArticlePDF–768K
16.
Salivary Histatin 5 Is an Inhibitor of Both Host and Bacterial Enzymes Implicated in Periodontal Disease
Heloisa Gusman, James Travis, Eva J. Helmerhorst, Jan Potempa, Robert F. Troxler, Frank G. Oppenheim
Infect Immun. 2001 Mar; 69(3): 1402–1408. doi: 10.1128/IAI.69.3.1402-1408.2001
PMCID:
PMC98034
AbstractArticlePDF–111K
17.
A systematic survey of loss-of-function variants in human protein-coding genes
Daniel G. MacArthur, Suganthi Balasubramanian, Adam Frankish, Ni Huang, James Morris, Klaudia Walter, Luke Jostins, Lukas Habegger, Joseph K. Pickrell, Stephen B. Montgomery, Cornelis A. Albers, Zhengdong Zhang, Donald F. Conrad, Gerton Lunter, Hancheng Zheng, Qasim Ayub, Mark A. DePristo, Eric Banks, Min Hu, Robert E. Handsaker, Jeffrey Rosenfeld, Menachem Fromer, Mike Jin, Xinmeng Jasmine Mu, Ekta Khurana, Kai Ye, Mike Kay, Gary Ian Saunders, Marie-Marthe Suner, Toby Hunt, If H.A. Barnes, Clara Amid, Denise R. Carvalho-Silva, Alexandra H Bignell, Catherine Snow, Bryndis Yngvadottir, Suzannah Bumpstead, David N. Cooper, Yali Xue, Irene Gallego Romero, 1000 Genomes Project Consortium, Jun Wang, Yingrui Li, Richard A. Gibbs, Steven A. McCarroll, Emmanouil T. Dermitzakis, Jonathan K. Pritchard, Jeffrey C. Barrett, Jennifer Harrow, Matthew E. Hurles, Mark B. Gerstein, Chris Tyler-Smith
Science. Author manuscript; available in PMC 2012 Aug 17.
Published in final edited form as: Science. 2012 Feb 17; 335(6070): 823–828. doi: 10.1126/science.1215040
Correction in:
volume 336 on page 296
PMCID:
PMC3299548
AbstractArticlePDF–1.0M
18.
In Vitro Identification of Histatin 5 Salivary Complexes
Eduardo B. Moffa, Maria A. A. M. Machado, Maria C. M. Mussi, Yizhi Xiao, Saulo S. Garrido, Eunice T. Giampaolo, Walter L. Siqueira
PLoS One. 2015; 10(11): e0142517. Published online 2015 Nov 6. doi: 10.1371/journal.pone.0142517
PMCID:
PMC4636238
AbstractArticlePDF–539K
19.
The mutational constraint spectrum quantified from variation in 141,456 humans
Konrad J. Karczewski, Laurent C. Francioli, Grace Tiao, Beryl B. Cummings, Jessica Alföldi, Qingbo Wang, Ryan L. Collins, Kristen M. Laricchia, Andrea Ganna, Daniel P. Birnbaum, Laura D. Gauthier, Harrison Brand, Matthew Solomonson, Nicholas A. Watts, Daniel Rhodes, Moriel Singer-Berk, Eleina M. England, Eleanor G. Seaby, Jack A. Kosmicki, Raymond K. Walters, Katherine Tashman, Yossi Farjoun, Eric Banks, Timothy Poterba, Arcturus Wang, Cotton Seed, Nicola Whiffin, Jessica X. Chong, Kaitlin E. Samocha, Emma Pierce-Hoffman, Zachary Zappala, Anne H. O’Donnell-Luria, Eric Vallabh Minikel, Ben Weisburd, Monkol Lek, James S. Ware, Christopher Vittal, Irina M. Armean, Louis Bergelson, Kristian Cibulskis, Kristen M. Connolly, Miguel Covarrubias, Stacey Donnelly, Steven Ferriera, Stacey Gabriel, Jeff Gentry, Namrata Gupta, Thibault Jeandet, Diane Kaplan, Christopher Llanwarne, Ruchi Munshi, Sam Novod, Nikelle Petrillo, David Roazen, Valentin Ruano-Rubio, Andrea Saltzman, Molly Schleicher, Jose Soto, Kathleen Tibbetts, Charlotte Tolonen, Gordon Wade, Michael E. Talkowski, Genome Aggregation Database Consortium, Benjamin M. Neale, Mark J. Daly, Daniel G. MacArthur
Nature. 2020; 581(7809): 434–443. Published online 2020 May 27. doi: 10.1038/s41586-020-2308-7
Correction in:
Nature. 2021; 590(7846): E53.
PMCID:
PMC7334197
AbstractArticlePDF–3.1M
20.
Common homozygosity for predicted loss-of-function variants reveals both redundant and advantageous effects of dispensable human genes
Antonio Rausell, Yufei Luo, Marie Lopez, Yoann Seeleuthner, Franck Rapaport, Antoine Favier, Peter D. Stenson, David N. Cooper, Etienne Patin, Jean-Laurent Casanova, Lluis Quintana-Murci, Laurent Abel
Proc Natl Acad Sci U S A. 2020 Jun 16; 117(24): 13626–13636. Published online 2020 Jun 2. doi: 10.1073/pnas.1917993117
PMCID:
PMC7306792
AbstractArticlePDF–1.0M

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