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Select item 106641841.

IRF8 as a Novel Marker to Differentiate Between CD30-Positive Large Cell Lymphomas

Daniel C McQuaid, Samuel G Katz, Mina L Xu

Am J Clin Pathol. 2022 Aug; 158(2): 173–176. Published online 2022 Apr 23. doi: 10.1093/ajcp/aqac044

Correction in:: Am J Clin Pathol. 2024 Jan; 161(1): 107.

PMCID:: PMC10664184

Abstract Article PDF–4.6M

Select item 106216572.

Global assessment of IRF8 as a novel cancer biomarker

Daniel C. McQuaid, Gauri Panse, Wei-Lien Wang, Geraldine S. Pinkus, Samuel G. Katz, Mina L. Xu

Hum Pathol. Author manuscript; available in PMC 2023 Nov 2.

Published in final edited form as: Hum Pathol. 2022 Apr; 122: 1–10. Published online 2022 Jan 24. doi: 10.1016/j.humpath.2022.01.004

PMCID:: PMC10621657

Abstract Article PDF–2.2M

Select item 103783153.

Expression of Interferon Regulatory Factor 8 (IRF8) and Its Association with Infections in Dialysis Patients

Justa Friebus-Kardash, Fei Kuang, Tobias Peitz, Thamer A. Hamdan, Ute Eisenberger, Kristina Boss, Andreas Kribben, Karl Sebastian Lang, Michael Jahn

Cells. 2023 Jul; 12(14): 1892. Published online 2023 Jul 19. doi: 10.3390/cells12141892

PMCID:: PMC10378315

Abstract Article PDF–1.8M

Select item 90363924.

Expression of the Interferon Regulatory Factor 8/ICSBP-1 in Human Reactive Lymphoid Tissues and B-cell Lymphomas: A Novel Germinal Center Marker

Antonio Martinez, Stefania Pittaluga, Martina Rudelius, Theresa Davies-Hill, Denise Sebasigari, Thomas J. Fountaine, Stephen Hewitt, Elaine S. Jaffe, Mark Raffeld

Am J Surg Pathol. Author manuscript; available in PMC 2022 Apr 25.

Published in final edited form as: Am J Surg Pathol. 2008 Aug; 32(8): 1190–1200. doi: 10.1097/PAS.0b013e318166f46a

PMCID:: PMC9036392

Abstract Article PDF–4.1M

Select item 90062715.

IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma

Suraya Elfrink, Martin ter Beest, Luuk Janssen, Marijke P. Baltissen, Pascal W. T. C. Jansen, Angelique N. Kenyon, Raymond M. Steen, Daynelys de Windt, Philipp M. Hagemann, Corine Hess, Dick-Johan van Spronsen, Brigiet Hoevenaars, Ellen van der Spek, Zijun Y. Xu-Monette, Ken H. Young, Charlotte Kaffa, Sander Bervoets, Jolien van Heek, Eva Hesius, Charlotte M. de Winde, Michiel Vermeulen, Michiel van den Brand, Blanca Scheijen, Annemiek B. van Spriel

Blood Adv. 2022 Apr 12; 6(7): 2254–2266. Published online 2022 Apr 4. doi: 10.1182/bloodadvances.2021004366

PMCID:: PMC9006271

Abstract Article PDF–1.6M

Select item 89870796.

Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery

Tian Zhou, Xinyi Zhu, Zhizhong Ye, Yong-Fei Wang, Chao Yao, Ning Xu, Mi Zhou, Jianyang Ma, Yuting Qin, Yiwei Shen, Yuanjia Tang, Zhihua Yin, Hong Xu, Yutong Zhang, Xiaoli Zang, Huihua Ding, Wanling Yang, Ya Guo, John B. Harley, Bahram Namjou, Kenneth M. Kaufman, Leah C. Kottyan, Matthew T. Weirauch, Guojun Hou, Nan Shen

Nat Commun. 2022; 13: 1855. Published online 2022 Apr 6. doi: 10.1038/s41467-022-29514-y

PMCID:: PMC8987079

Abstract Article PDF–2.1M

Select item 79928287.

High IRF8 expression correlates with CD8 T cell infiltration and is a predictive biomarker of therapy response in ER-negative breast cancer

Gerardo Gatti, Courtney Betts, Darío Rocha, Maribel Nicola, Verónica Grupe, Cecilia Ditada, Nicolas G. Nuñez, Emiliano Roselli, Paula Araya, Jeremías Dutto, Lucia Boffelli, Elmer Fernández, Lisa M. Coussens, Mariana Maccioni

Breast Cancer Res. 2021; 23: 40. Published online 2021 Mar 25. doi: 10.1186/s13058-021-01418-7

Correction in:: Breast Cancer Res. 2021; 23: 48.

PMCID:: PMC7992828

Abstract Article PDF–6.2M

Select item 76149938.

Circulating IRF8-expressing CD123⁺CD127⁺ lymphoid progenitors: key players in human hematopoiesis

Kai Ling Liang, Elisa Laurenti, Tom Taghon

Trends Immunol. Author manuscript; available in PMC 2023 Sep 1.

Published in final edited form as: Trends Immunol. 2023 Aug 15; 44(9): 678–692. Published online 2023 Aug 15. doi: 10.1016/j.it.2023.07.004

PMCID:: PMC7614993

Abstract Article PDF–1.8M

Select item 74479829.

Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans

Urszula Cytlak, Anastasia Resteu, Sarah Pagan, Kile Green, Paul Milne, Sheetal Maisuria, David McDonald, Gillian Hulme, Andrew Filby, Benjamin Carpenter, Rachel Queen, Sophie Hambleton, Rosie Hague, Hana Lango Allen, James E.D. Thaventhiran, Gina Doody, Matthew Collin, Venetia Bigley

Immunity. 2020 Aug 18; 53(2): 353–370.e8. doi: 10.1016/j.immuni.2020.07.003

PMCID:: PMC7447982

Abstract Article

Select item 704174610.

Single-cell RNA sequencing of immune cells in gastric cancer patients

Kai Fu, Bingqing Hui, Qian Wang, Chen Lu, Weihong Shi, Zhigang Zhang, Dawei Rong, Betty Zhang, Zhaofeng Tian, Weiwei Tang, Hongyong Cao, Xuehao Wang, Ziyi Chen

Aging (Albany NY) 2020 Feb 15; 12(3): 2747–2763. Published online 2020 Feb 10. doi: 10.18632/aging.102774

PMCID:: PMC7041746

Abstract Article PDF–3.1M

Select item 692769011.

IRF8 induces senescence of lung cancer cells to exert its tumor suppressive function

Jinxia Liang, Feng Lu, Bo Li, Lu Liu, Guandi Zeng, Qian Zhou, Liang Chen

Cell Cycle. 2019; 18(23): 3300–3312. Published online 2019 Oct 9. doi: 10.1080/15384101.2019.1674053

PMCID:: PMC6927690

Abstract Article PDF–4.9M

Select item 658508012.

Tumor-associated macrophage expression of interferon regulatory Factor-8 (IRF8) is a predictor of progression and patient survival in renal cell carcinoma

Jason B. Muhitch, Nicholas C. Hoffend, Gissou Azabdaftari, Austin Miller, Wiam Bshara, Carl D. Morrison, Thomas Schwaab, Scott I. Abrams

J Immunother Cancer. 2019; 7: 155. Published online 2019 Jun 20. doi: 10.1186/s40425-019-0630-0

PMCID:: PMC6585080

Abstract Article PDF–2.4M

Select item 556480513.

Increased expression of IRF8 in tumor cells inhibits the generation of Th17 cells and predicts unfavorable survival of diffuse large B cell lymphoma patients

Wei-Jie Zhong, Xin Xu, Zhi-Gang Zhu, Qing-Hua Du, Hong Du, Li Yang, Yan-Ying Ling, Hua-Bao Xiong, Qing-Shan Li

Oncotarget. 2017 Jul 25; 8(30): 49757–49772. Published online 2017 May 8. doi: 10.18632/oncotarget.17693

PMCID:: PMC5564805

Abstract Article PDF–5.6M

Select item 556473214.

The tumor suppressor interferon regulatory factor 8 inhibits β-catenin signaling in breast cancers, but is frequently silenced by promoter methylation

Xinrong Luo, Xin Xiong, Qing Shao, Tingxiu Xiang, Lili Li, Xuedong Yin, Xia Li, Qian Tao, Guosheng Ren

Oncotarget. 2017 Jul 25; 8(30): 48875–48888. Published online 2017 Mar 23. doi: 10.18632/oncotarget.16511

PMCID:: PMC5564732

Abstract Article PDF–6.8M

Select item 554590015.

Total cellular protein presence of the transcription factor IRF8 does not necessarily correlate with its nuclear presence

Hans Minderman, Orla Maguire, Kieran L. O’Loughlin, Jason Muhitch, Paul K. Wallace, Scott I. Abrams

Methods. Author manuscript; available in PMC 2017 Aug 7.

Published in final edited form as: Methods. 2017 Jan 1; 112: 84–90. Published online 2016 Aug 28. doi: 10.1016/j.ymeth.2016.08.011

PMCID:: PMC5545900

Abstract Article PDF–870K

Select item 552071716.

All-trans retinoic acid and arsenic trioxide fail to derepress the monocytic differentiation driver Irf8 in acute promyelocytic leukemia cells

XiangZhen Liu, Juan Chen, ShanHe Yu, Li Yan, HeZhou Guo, JianMin Dai, Wu Zhang, Jiang Zhu

Cell Death Dis. 2017 May; 8(5): e2782. Published online 2017 May 11. doi: 10.1038/cddis.2017.197

PMCID:: PMC5520717

Abstract Article PDF–2.5M

Select item 404785417.

Interferon consensus sequence-binding protein (ICSBP) promotes epithelial-to-mesenchymal transition (EMT)-like phenomena, cell-motility, and invasion via TGF-β signaling in U2OS cells

J Y Sung, S-Y Park, J H Kim, H G Kang, J H Yoon, Y S Na, Y-N Kim, B-K Park

Cell Death Dis. 2014 May; 5(5): e1224. Published online 2014 May 15. doi: 10.1038/cddis.2014.189

PMCID:: PMC4047854

Abstract Article PDF–2.9M

Select item 374384518.

The Prognostic Significance of IRF8 Transcripts in Adult Patients with Acute Myeloid Leukemia

Era L. Pogosova-Agadjanyan, Kenneth J. Kopecky, Fabiana Ostronoff, Frederick R. Appelbaum, John Godwin, Hana Lee, Alan F. List, Jennifer J. May, Vivian G. Oehler, Steve Petersdorf, Galina L. Pogosov, Jerald P. Radich, Cheryl L. Willman, Soheil Meshinchi, Derek L. Stirewalt

PLoS One. 2013; 8(8): e70812. Published online 2013 Aug 14. doi: 10.1371/journal.pone.0070812

PMCID:: PMC3743845

Abstract Article PDF–832K

Select item 359642819.

Mapping of the IRF8 gene identifies a 3’ UTR variant associated with risk of chronic lymphocytic leukemia but not other common non-Hodgkin lymphoma subtypes

Susan L. Slager, Sara J. Achenbach, Yan W. Asmann, Nicola J. Camp, Kari G. Rabe, Lynn R. Goldin, Timothy G. Call, Tait D. Shanafelt, Neil E. Kay, Julie M. Cunningham, Alice H. Wang, J. Brice Weinberg, Aaron D. Norman, Brian K. Link, Jose F. Leis, Celine M. Vachon, Mark C. Lanasa, Neil E. Caporaso, Anne J. Novak, James R. Cerhan

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2013 Mar; 22(3): 461–466. Published online 2013 Jan 10. doi: 10.1158/1055-9965.EPI-12-1217

PMCID:: PMC3596428

Abstract Article PDF–52K

Select item 313655420.

Mutations in IRF8 and Human Dendritic Cell Immunodeficiency

Sophie Hambleton, Sandra Salem, Jacinta Bustamante, Venetia Bigley, Stéphanie Boisson-Dupuis, Joana Azevedo, Anny Fortin, Muzlifah Haniffa, Lourdes Ceron-Gutierrez, Chris Bacon, Geetha Menon, Céline Trouillet, David McDonald, Peter Carey, Florent Ginhoux, Laia Alsina, Timothy J Zumwalt, Xiaofei Kong, Dinakantha Kumararatne, Karina Butler, Marjorie Hubeau, Jacqueline Feinberg, Saleh Al-Muhsen, Andrew Cant, Laurent Abel, Damien Chaussabel, Rainer Doffinger, Eduardo Talesnik, Anete Grumach, Alberto Duarte, Katia Abarca, Dewton Moraes-Vasconcelos, David Burk, Albert Berghuis, Frédéric Geissmann, Matthew Collin, Jean-Laurent Casanova, Philippe Gros

N Engl J Med. Author manuscript; available in PMC 2011 Jul 14.

Published in final edited form as: N Engl J Med. 2011 Jul 14; 365(2): 127–138. Published online 2011 Apr 27. doi: 10.1056/NEJMoa1100066

PMCID:: PMC3136554

Abstract Article PDF–3.4M

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PMC Links for Gene (Select 3394) (96)
PMC
muscleblind-like protein 1 isoform 11 [Homo sapiens]
muscleblind-like protein 1 isoform 11 [Homo sapiens]
gi|1777375976|ref|NP_001363750.1|

Protein
muscleblind-like protein 1 isoform 9 [Homo sapiens]
muscleblind-like protein 1 isoform 9 [Homo sapiens]
gi|1777375960|ref|NP_001363762.1|

Protein
muscleblind-like protein 1 isoform X4 [Homo sapiens]
muscleblind-like protein 1 isoform X4 [Homo sapiens]
gi|2462589851|ref|XP_054202521.1|

Protein
Homo sapiens muscleblind like splicing regulator 1 (MBNL1), transcript variant 6...
Homo sapiens muscleblind like splicing regulator 1 (MBNL1), transcript variant 63, mRNA
gi|1915575684|ref|NM_001387793.1|

Nucleotide

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