PMC Links for Gene (Select 3480) - PMC

Orsolya I. Gaal, Ruiqi Liu, Dragoș Marginean, Medeea Badii, Georgiana Cabău, Ioana Hotea, Valentin Nica, Doina Colcear, HINT Consortium, Cristina Pamfil, Tony R. Merriman, Simona Rednic, Radu A. Popp, Tania O. Crișan, Leo A. B. Joosten

Sci Rep. 2024; 14: 3565. Published online 2024 Feb 12. doi: 10.1038/s41598-024-53209-7

PMCID:: PMC10861580

Abstract Article PDF–1.6M

Select item 103558894.

Type 1 IGF Receptor Localization in Paediatric Gliomas: Significant Association with WHO Grading and Clinical Outcome

Florencia Clément, Ayelen Martin, Marcela Venara, Maria de Luján Calcagno, Cecilia Mathó, Silvana Maglio, Mercedes García Lombardi, Ignacio Bergadá, Patricia A Pennisi

Horm Cancer. 2018 Jun; 9(3): 205–214. Published online 2018 Mar 9. doi: 10.1007/s12672-018-0328-7

PMCID:: PMC10355889

Abstract Article PDF–819K

Select item 103557125.

Downregulation of IGF1R Expression Inhibits Growth and Enhances Cisplatin Sensitivity of Head and Neck Squamous Cell Carcinoma Cells In Vitro

Ashraf Khalil, Mark J. Jameson

Horm Cancer. 2019 Feb; 10(1): 11–23. Published online 2018 Oct 23. doi: 10.1007/s12672-018-0352-7

PMCID:: PMC10355712

Abstract Article PDF–1.5M

Select item 98754056.

IGF-1R down regulates the sensitivity of hepatocellular carcinoma to sorafenib through the PI3K / akt and RAS / raf / ERK signaling pathways

Wenpeng Cai, Yongfang Ma, Li Song, Niandie Cao, Jiafeng Gao, Shuping Zhou, Xiaolong Tang

BMC Cancer. 2023; 23: 87. Published online 2023 Jan 25. doi: 10.1186/s12885-023-10561-7

PMCID:: PMC9875405

Abstract Article PDF–2.5M

Select item 98230407.

A common IGF1R gene variant predicts later life breast cancer risk in women with preeclampsia

Mark Powell, Sophia Fuller, Erica Gunderson, Christopher Benz

Breast Cancer Res Treat. 2023; 197(1): 149–159. Published online 2022 Nov 4. doi: 10.1007/s10549-022-06789-9

PMCID:: PMC9823040

Abstract Article PDF–742K

Select item 96371448.

Interaction of a viral insulin-like peptide with the IGF-1 receptor produces a natural antagonist

Francois Moreau, Nicholas S. Kirk, Fa Zhang, Vasily Gelfanov, Edward O. List, Martina Chrudinová, Hari Venugopal, Michael C. Lawrence, Veronica Jimenez, Fatima Bosch, John J. Kopchick, Richard D. DiMarchi, Emrah Altindis, C. Ronald Kahn

Nat Commun. 2022; 13: 6700. Published online 2022 Nov 5. doi: 10.1038/s41467-022-34391-6

PMCID:: PMC9637144

Abstract Article PDF–2.6M

Select item 93559579.

Gemcitabine resistance of pancreatic cancer cells is mediated by IGF1R dependent upregulation of CD44 expression and isoform switching

Chen Chen, Shujie Zhao, Xiangru Zhao, Lin Cao, Anand Karnad, Addanki P. Kumar, James W. Freeman

Cell Death Dis. 2022 Aug; 13(8): 682. Published online 2022 Aug 5. doi: 10.1038/s41419-022-05103-1

PMCID:: PMC9355957

Abstract Article PDF–3.1M

Select item 931926210.

Integrated DNA Copy Number and Expression Profiling Identifies IGF1R as a Prognostic Biomarker in Pediatric Osteosarcoma

Aaron M. Taylor, Jiayi M. Sun, Alexander Yu, Horatiu Voicu, Jianhe Shen, Donald A. Barkauskas, Timothy J. Triche, Julie M. Gastier-Foster, Tsz-Kwong Man, Ching C. Lau

Int J Mol Sci. 2022 Jul; 23(14): 8036. Published online 2022 Jul 21. doi: 10.3390/ijms23148036

PMCID:: PMC9319262

Abstract Article PDF–1.7M

Select item 924723911.

Activation Versus Inhibition of IGF1R: A Dual Role in Breast Tumorigenesis

Joseph J. Bulatowicz, Teresa L. Wood

Front Endocrinol (Lausanne) 2022; 13: 911079. Published online 2022 Jun 17. doi: 10.3389/fendo.2022.911079

PMCID:: PMC9247239

Abstract Article PDF–842K

Select item 907122312.

Reduced cardiovascular risks in women with endometriosis or polycystic ovary syndrome carrying a common functional IGF1R variant

Mark J Powell, Sophia Fuller, Erica P Gunderson, Christopher C Benz

Hum Reprod. 2022 May; 37(5): 1083–1094. Published online 2022 Apr 1. doi: 10.1093/humrep/deac059

PMCID:: PMC9071223

Abstract Article PDF–515K

Select item 775405513.

DM‐induced Hypermethylation of IR and IGF1R attenuates mast cell activation and airway responsiveness in rats

Dan Fu, Hailu Zhao, Liang He, Huafeng Feng

J Cell Mol Med. 2020 Dec; 24(24): 14381–14391. Published online 2020 Nov 3. doi: 10.1111/jcmm.16059

PMCID:: PMC7754055

Abstract Article PDF–1.3M

Select item 772609614.

A Novel Mutation in Insulin-Like Growth Factor-1 Receptor (c.641-2A>G) Is Associated with Impaired Growth, Hypoglycemia, and Modified Immune Phenotypes

Melanie R. Shapiro, Timothy P. Foster, Daniel J. Perry, Ron G. Rosenfeld, Andrew Dauber, James A. McNichols, Andrew Muir, Vivian Hwa, Todd M. Brusko, Laura M. Jacobsen

Horm Res Paediatr. Author manuscript; available in PMC 2021 Oct 28.

Published in final edited form as: Horm Res Paediatr. 2020; 93(5): 322–334. Published online 2020 Oct 28. doi: 10.1159/000510764

PMCID:: PMC7726096

Abstract Article PDF–2.5M

Select item 741563615.

Insulin-like growth factor-1 receptor expression and disease recurrence and survival in patients with resected pancreatic ductal adenocarcinoma

Chunxia Du, Annacarolina da Silva, Vicente Morales-Oyarvide, Andressa Dias Costa, Margaret M. Kozak, Richard F. Dunne, Douglas A. Rubinson, Kimberly Perez, Yohei Masugi, Tsuyoshi Hamada, Lauren K. Brais, Chen Yuan, Ana Babic, Matthew D. Ducar, Aaron R. Thorner, Andrew J. Aguirre, Matthew H. Kulke, Kimmie Ng, Thomas E. Clancy, Jennifer J. Findeis-Hosey, Daniel T. Chang, Jason L. Hornick, Charles S. Fuchs, Shuji Ogino, Albert C. Koong, Aram F. Hezel, Brian M. Wolpin, Jonathan A. Nowak

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2020 Aug; 29(8): 1586–1595. Published online 2020 May 28. doi: 10.1158/1055-9965.EPI-19-1315

PMCID:: PMC7415636

Abstract Article PDF–817K

Select item 739153316.

Questioning the IGF1 receptor’s assigned role in CRC – a case for rehabilitation?

Steffen M. Heckl, Marie Pellinghaus, Hans-Michael Behrens, Sandra Krüger, Stefan Schreiber, Christoph Röcken

BMC Cancer. 2020; 20: 704. Published online 2020 Jul 29. doi: 10.1186/s12885-020-07173-w

PMCID:: PMC7391533

Abstract Article PDF–1.6M

Select item 738856217.

IGF-IR promotes clonal cell proliferation in myelodysplastic syndromes via inhibition of the MAPK pathway

Qi He, Qingqing Zheng, Feng Xu, Wenhui Shi, Juan Guo, Zheng Zhang, Sida Zhao, Xiao Li, Chunkang Chang

Oncol Rep. 2020 Sep; 44(3): 1094–1104. Published online 2020 Jun 19. doi: 10.3892/or.2020.7652

PMCID:: PMC7388562

Abstract Article PDF–1.9M

Select item 726862818.

Insulin-like growth factor receptor signaling in tumorigenesis and drug resistance: a challenge for cancer therapy

Hui Hua, Qingbin Kong, Jie Yin, Jin Zhang, Yangfu Jiang

J Hematol Oncol. 2020; 13: 64. Published online 2020 Jun 3. doi: 10.1186/s13045-020-00904-3

PMCID:: PMC7268628

Abstract Article PDF–928K

Select item 698591319.

Sterol structure dependence of insulin receptor and insulin-like growth factor 1 receptor activation

Richard J. Delle Bovi, JiHyun Kim, Pavana Suresh, Erwin London, W. Todd Miller

Biochim Biophys Acta Biomembr. Author manuscript; available in PMC 2020 Jan 28.

Published in final edited form as: Biochim Biophys Acta Biomembr. 2019 Apr 1; 1861(4): 819–826. Published online 2019 Jan 22. doi: 10.1016/j.bbamem.2019.01.009

PMCID:: PMC6985913

Abstract Article PDF–1.3M

Select item 695310920.

Non-Coding RNAs in IGF-1R Signaling Regulation: The Underlying Pathophysiological Link between Diabetes and Cancer

Baoqing Chen, Junyan Li, Dongmei Chi, Iman Sahnoune, Steliana Calin, Leonard Girnita, George A. Calin

Cells. 2019 Dec; 8(12): 1638. Published online 2019 Dec 14. doi: 10.3390/cells8121638

PMCID:: PMC6953109

Abstract Article PDF–1.5M

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