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Select item 110116961.

Dysfunction in IGF2R Pathway and Associated Perturbations in Autophagy and WNT Processes in Beckwith–Wiedemann Syndrome Cell Lines

Silvana Pileggi, Elisa A. Colombo, Silvia Ancona, Roberto Quadri, Clara Bernardelli, Patrizia Colapietro, Michela Taiana, Laura Fontana, Monica Miozzo, Elena Lesma, Silvia M. Sirchia

Int J Mol Sci. 2024 Apr; 25(7): 3586. Published online 2024 Mar 22. doi: 10.3390/ijms25073586

PMCID:: PMC11011696

Abstract Article PDF–2.6M

Select item 95921182.

Proteomics analysis of cancer tissues identifies IGF2R as a potential therapeutic target in laryngeal carcinoma

Bing Liu, Yuqiang Hu, Lixia Wan, Luan Wang, Liangjun Cheng, Hai Sun, Yaran Liu, Di Wu, Jiefei Zhu, Xiu Hong, Yang Li, Chong Zhou

Front Endocrinol (Lausanne) 2022; 13: 1031210. Published online 2022 Oct 10. doi: 10.3389/fendo.2022.1031210

PMCID:: PMC9592118

Abstract Article PDF–29M

Select item 83124453.

IGF IIRα-triggered pathological manifestations in the heart aggravate renal inflammation in STZ-induced type-I diabetes rats

Henry Cherng-Han Lin, Catherine Reena Paul, Chia-Hua Kuo, Yung-Hsien Chang, William Shao-Tsu Chen, Tsung-Jung Ho, Cecilia Hsuan Day, Vijaya Padma Viswanadha, Yuhsin Tsai, Chih-Yang Huang

Aging (Albany NY) 2021 Jul 15; 13(13): 17536–17547. Published online 2021 Jul 7. doi: 10.18632/aging.203244

PMCID:: PMC8312445

Abstract Article PDF–951K

Select item 74817954.

Allosteric regulation of lysosomal enzyme recognition by the cation-independent mannose 6-phosphate receptor

Linda J. Olson, Sandeep K. Misra, Mayumi Ishihara, Kevin P. Battaile, Oliver C. Grant, Amika Sood, Robert J. Woods, Jung-Ja P. Kim, Michael Tiemeyer, Gang Ren, Joshua S. Sharp, Nancy M. Dahms

Commun Biol. 2020; 3: 498. Published online 2020 Sep 9. doi: 10.1038/s42003-020-01211-w

PMCID:: PMC7481795

Abstract Article PDF–4.1M

Select item 68680135.

Upregulation of IGF2R evades lysosomal dysfunction-induced apoptosis of cervical cancer cells via transport of cathepsins

Takashi Takeda, Masayuki Komatsu, Fumiko Chiwaki, Rie Komatsuzaki, Kanako Nakamura, Kosuke Tsuji, Yusuke Kobayashi, Eiichiro Tominaga, Masaya Ono, Kouji Banno, Daisuke Aoki, Hiroki Sasaki

Cell Death Dis. 2019 Dec; 10(12): 876. Published online 2019 Nov 20. doi: 10.1038/s41419-019-2117-9

PMCID:: PMC6868013

Abstract Article PDF–3.2M

Select item 63840626.

Insulin-Like Growth Factor 2 Receptor Expression Is Promoted by Human Herpesvirus 8-Encoded Interleukin-6 and Contributes to Viral Latency and Productive Replication

Qian Li, Daming Chen, Qiwang Xiang, John Nicholas

J Virol. 2019 Mar 1; 93(5): e02026-18. Prepublished online 2018 Dec 12. Published online 2019 Feb 19. doi: 10.1128/JVI.02026-18

PMCID:: PMC6384062

Abstract Article PDF–3.9M

Select item 56748907.

Sequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR

Boris Simonetti, Chris M. Danson, Kate J. Heesom, Peter J. Cullen

J Cell Biol. 2017 Nov 6; 216(11): 3695–3712. doi: 10.1083/jcb.201703015

PMCID:: PMC5674890

Abstract Article PDF–5.0M

Select item 56748888.

Cargo-selective SNX-BAR proteins mediate retromer trimer independent retrograde transport

Arunas Kvainickas, Ana Jimenez-Orgaz, Heike Nägele, Zehan Hu, Jörn Dengjel, Florian Steinberg

J Cell Biol. 2017 Nov 6; 216(11): 3677–3693. doi: 10.1083/jcb.201702137

PMCID:: PMC5674888

Abstract Article PDF–4.9M

Select item 46587039.

An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution

Christopher Williams, Hans-Jürgen Hoppe, Dellel Rezgui, Madeleine Strickland, Briony E. Forbes, Frank Grutzner, Susana Frago, Rosamund Z. Ellis, Pakorn Wattana-Amorn, Stuart N. Prince, Oliver J. Zaccheo, Catherine M. Nolan, Andrew J. Mungall, E. Yvonne Jones, Matthew P. Crump, A. Bassim Hassan

Science. Author manuscript; available in PMC 2015 Nov 25.

Published in final edited form as: Science. 2012 Nov 30; 338(6111): 1209–1213. doi: 10.1126/science.1228633

PMCID:: PMC4658703

Abstract Article PDF–1.5M

Select item 439894210.

The Association of Soluble IGF2R and IGF2R Gene Polymorphism with Type 2 Diabetes

Suwannee Chanprasertyothin, Wallaya Jongjaroenprasert, Boonsong Ongphiphadhanakul

J Diabetes Res. 2015; 2015: 216383. Published online 2015 Apr 2. doi: 10.1155/2015/216383

PMCID:: PMC4398942

Abstract Article PDF–492K

Select item 436588211.

Elevation of IGF-2 receptor and the possible underlying implications in end-stage heart failure patients before and after heart transplantation

Yingjie Wei, Jun Li, Jie Huang, Xiaoling Zhang, Hong Zhao, Chuanjue Cui, Yishi Li, Shengshou Hu

J Cell Mol Med. 2012 May; 16(5): 1038–1046. Published online 2012 Apr 26. doi: 10.1111/j.1582-4934.2011.01414.x

PMCID:: PMC4365882

Abstract Article PDF–542K

Select item 363208712.

The mannose 6-phosphate-binding sites of M6P/IGF2R determine its capacity to suppress matrix invasion by squamous cell carcinoma cells

Olivia C. Probst, Evren Karayel, Nicole Schida, Elisabeth Nimmerfall, Elisabeth Hehenberger, Verena Puxbaum, Lukas Mach

Biochem J. 2013 Apr 1; 451(Pt 1): 91–99. Prepublished online 2013 Jan 25. Published online 2013 Mar 14. doi: 10.1042/BJ20121422

PMCID:: PMC3632087

Abstract Article PDF–671K

Select item 339113513.

Dissecting Mannose 6-Phosphate-Insulin-like Growth Factor 2 Receptor Complexes That Control Activation and Uptake of Plasminogen in Cells

Vladimir Leksa, Karin Pfisterer, Gabriela Ondrovičová, Brigitte Binder, Silvia Lakatošová, Clemens Donner, Herbert B. Schiller, Alexander Zwirzitz, Katarína Mrvová, Vladimir Pevala, Eva Kutejová, Hannes Stockinger

J Biol Chem. 2012 Jun 29; 287(27): 22450–22462. Published online 2012 May 21. doi: 10.1074/jbc.M112.339663

PMCID:: PMC3391135

Abstract Article PDF–2.1M

Select item 304312714.

IGF2 Actions on Trophoblast in Human Placenta Are Regulated by the Insulin-Like Growth Factor 2 Receptor, Which Can Function as Both a Signaling and Clearance Receptor

Lynda K. Harris, Ian P. Crocker, Philip N. Baker, John D. Aplin, Melissa Westwood

Biol Reprod. 2011 Mar; 84(3): 440–446. Published online 2010 Oct 27. doi: 10.1095/biolreprod.110.088195

PMCID:: PMC3043127

Abstract Article PDF–1.5M

Select item 300865615.

IGF2R Polymorphisms and Risk of Esophageal and Gastric Adenocarcinomas

Cathrine Hoyo, Joellen M. Schildkraut, Susan K. Murphy, Wong-Ho Chow, Thomas L. Vaughan, Harvey Risch, Jeffrey R. Marks, Randy L. Jirtle, Brian Calingeart, Susan Mayne, Joseph Fraumeni, Jr., Marilie D. Gammon

Int J Cancer. Author manuscript; available in PMC 2010 Dec 22.

Published in final edited form as: Int J Cancer. 2009 Dec 1; 125(11): 2673–2678. doi: 10.1002/ijc.24623

Correction in:: volume 126 on page 799

PMCID:: PMC3008656

Abstract Article PDF–314K

Select item 287820516.

IGF2R Missense Single-Nucleotide Polymorphisms and Breast Cancer Risk: The Multiethnic Cohort Study

Iona Cheng, Daniel O. Stram, Noël P. Burtt, Lauren Gianniny, Rachel R. Garcia, Loreall Pooler, Brian E. Henderson, Loïc Le Marchand, Christopher A Haiman

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2010 May 28.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2009 Jun; 18(6): 1922–1924. Published online 2009 May 12. doi: 10.1158/1055-9965.EPI-09-0253

PMCID:: PMC2878205

Abstract Article PDF–47K

Select item 274865017.

High-Affinity Ligand Binding by Wild-Type:Mutant Heteromeric Complexes of the Mannose 6-Phosphate/Insulin-like Growth Factor II Receptors

Michelle A. Hartman, Jodi L. Kreiling, James C. Byrd, Richard G. MacDonald

FEBS J. Author manuscript; available in PMC 2009 Oct 1.

Published in final edited form as: FEBS J. 2009 Apr; 276(7): 1915–1929. Published online 2009 Feb 19. doi: 10.1111/j.1742-4658.2009.06917.x

PMCID:: PMC2748650

Abstract Article PDF–409K

Select item 13618618.

Cation-Independent Mannose 6-Phosphate Receptor Blocks Apoptosis Induced by Herpes Simplex Virus 1 Mutants Lacking Glycoprotein D and Is Likely the Target of Antiapoptotic Activity of the Glycoprotein

Guoying Zhou, Bernard Roizman

J Virol. 2002 Jun; 76(12): 6197–6204. doi: 10.1128/JVI.76.12.6197-6204.2002

PMCID:: PMC136186

Abstract Article PDF–1.4M

Select item 12589519.

Structure of a functional IGF2R fragment determined from the anomalous scattering of sulfur

James Brown, Robert M. Esnouf, Margaret A. Jones, Jane Linnell, Karl Harlos, A.Bassim Hassan, E.Yvonne Jones

EMBO J. 2002 Mar 1; 21(5): 1054–1062. doi: 10.1093/emboj/21.5.1054

PMCID:: PMC125895

Abstract Article PDF–470K

Select item 11779520.

Decreased expression of the mannose 6- phosphate/insulin-like growth factor-II receptor promotes growth of human breast cancer cells

Zhihong Chen, Yinlin Ge, Natalie Landman, Jing X Kang

BMC Cancer. 2002; 2: 18. Published online 2002 Jul 30. doi: 10.1186/1471-2407-2-18

PMCID:: PMC117795

Abstract Article PDF–685K

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PMC Links for Gene (Select 3482) (171)
PMC
hypothetical protein IFM46972_05250 [Aspergillus udagawae]
hypothetical protein IFM46972_05250 [Aspergillus udagawae]
gi|1805418143|dbj|GFF37524.1||gnl|W KC|GFF37524

Protein
Microgastrinae sp. USNM00681664 cytochrome oxidase subunit 1 (COI) gene, partial...
Microgastrinae sp. USNM00681664 cytochrome oxidase subunit 1 (COI) gene, partial cds; mitochondrial
gi|299558287|gnl|uoguelph|ASPNI844- I-5P|gb|HM373913.1|

Nucleotide

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