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Select item 98045201.

Low CD49d expression in newly diagnosed chronic lymphocytic leukaemia may be associated with high‐risk features and reduced treatment‐free‐intervals

Smyth Elizabeth, Kelly Aidan, O' Brien David, Waldron Deirdre, Brophy Sarah, Atkinson Emer, Perera Kanthi, Gerard M. Crotty, Walsh Aileen, Connolly Michelle, Clifford Ruth, O'Leary Hilary, Khan Ashique, Christopher L. Bacon, Smyth Emily, Anthony M. McElligott, Quinn Fiona, Vandenberghe Elisabeth, Waldron Carmel

Eur J Haematol. 2022 Nov; 109(5): 441–446. Published online 2022 Aug 9. doi: 10.1111/ejh.13824

PMCID:: PMC9804520

Abstract Article PDF–830K

Select item 90831302.

Integrin α4 up-regulation activates the hedgehog pathway to promote arsenic and benzo[α]pyrene co-exposure-induced cancer stem cell-like property and tumorigenesis

Jie Xie, Ping Yang, Hsuan-Pei Lin, Yunfei Li, Marco Clementino, William Fenske, Chengfeng Yang, Chunhong Wang, Zhishan Wang

Cancer Lett. Author manuscript; available in PMC 2022 May 9.

Published in final edited form as: Cancer Lett. 2020 Nov 28; 493: 143–155. Published online 2020 Aug 26. doi: 10.1016/j.canlet.2020.08.015

PMCID:: PMC9083130

Abstract Article PDF–2.3M

Select item 72284643.

CD49d promotes disease progression in chronic lymphocytic leukemia: new insights from CD49d bimodal expression

Erika Tissino, Federico Pozzo, Dania Benedetti, Chiara Caldana, Tamara Bittolo, Francesca Maria Rossi, Riccardo Bomben, Paola Nanni, Hillarj Chivilò, Ilaria Cattarossi, Eva Zaina, Kevin Norris, Jerry Polesel, Massimo Gentile, Giovanni Tripepi, Riccardo Moia, Enrico Santinelli, Idanna Innocenti, Jacopo Olivieri, Giovanni D’Arena, Luca Laurenti, Francesco Zaja, Gabriele Pozzato, Annalisa Chiarenza, Francesco Di Raimondo, Davide Rossi, Chris Pepper, Tanja Nicole Hartmann, Gianluca Gaidano, Giovanni Del Poeta, Valter Gattei, Antonella Zucchetto

Blood. 2020 Apr 9; 135(15): 1244–1254. Prepublished online 2020 Jan 31. doi: 10.1182/blood.2019003179

PMCID:: PMC7228464

Abstract Article

Select item 66501394.

AGT haplotype in ITGA4 gene is related to antibody-mediated rejection in heart transplant patients

Lucía Núñez, Grecia M. Marrón-Liñares, María G. Crespo-Leiro, Eduardo Barge-Caballero, Eloy Álvarez-López, Natalia Suarez-Fuentetaja, María Jesús Paniagua-Martin, Jorge Pombo, Javier Muñiz, Carmela D. Tan, E. René Rodríguez, José Manuel Vázquez-Rodríguez, Manuel Hermida-Prieto

PLoS One. 2019; 14(7): e0219345. Published online 2019 Jul 23. doi: 10.1371/journal.pone.0219345

PMCID:: PMC6650139

Abstract Article PDF–1.2M

Select item 61288605.

Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes

Gabriel B. Ferguson, Ben Van Handel, Maxwell Bay, Petko Fiziev, Tonis Org, Siyoung Lee, Ruzanna Shkhyan, Nicholas W. Banks, Mila Scheinberg, Ling Wu, Biagio Saitta, Joseph Elphingstone, A. Noelle Larson, Scott M. Riester, April D. Pyle, Nicholas M. Bernthal, Hanna KA Mikkola, Jason Ernst, Andre J. van Wijnen, Michael Bonaguidi, Denis Evseenko

Nat Commun. 2018; 9: 3634. Published online 2018 Sep 7. doi: 10.1038/s41467-018-05573-y

PMCID:: PMC6128860

Abstract Article PDF–3.0M

Select item 58922386.

A Novel Association of Polymorphism in the ITGA4 Gene Encoding the VLA-4 α4 Subunit with Increased Risk of Alzheimer's Disease

Vladimira Durmanova, Zuzana Parnicka, Juraj Javor, Gabriel Minarik, Lubomir Vrazda, Barbora Vaseckova, Karin Gmitterova, Maria Kralova, Jan Pecenak, Peter Filipcik, Ivana Shawkatova

Mediators Inflamm. 2018; 2018: 7623823. Published online 2018 Mar 27. doi: 10.1155/2018/7623823

PMCID:: PMC5892238

Abstract Article PDF–691K

Select item 58671677.

Clinical relevance of integrin alpha 4 in gastrointestinal stromal tumours

Olli‐Pekka Pulkka, John‐Patrick Mpindi, Olli Tynninen, Bengt Nilsson, Olli Kallioniemi, Harri Sihto, Heikki Joensuu

J Cell Mol Med. 2018 Apr; 22(4): 2220–2230. Published online 2018 Jan 29. doi: 10.1111/jcmm.13502

PMCID:: PMC5867167

Abstract Article PDF–685K

Select item 57141428.

Do the expressions of epithelial–mesenchymal transition proteins, periostin, integrin-α4 and fibronectin correlate with clinico-pathological features and prognosis of metastatic castration-resistant prostate cancer?

Ece Konac, Ilker Kiliccioglu, Emrullah Sogutdelen, Asiye U Dikmen, Gulsah Albayrak, Cenk Y Bilen

Exp Biol Med (Maywood) 2017 Dec; 242(18): 1795–1801. Published online 2017 Aug 24. doi: 10.1177/1535370217728499

PMCID:: PMC5714142

Abstract Article PDF–215K

Select item 44054749.

B‐cell very late antigen‐4 deficiency reduces leukocyte recruitment and susceptibility to central nervous system autoimmunity

Klaus Lehmann‐Horn, Sharon A. Sagan, Claude C.A. Bernard, Raymond A. Sobel, Scott S. Zamvil

Ann Neurol. 2015 May; 77(5): 902–908. Published online 2015 Mar 28. doi: 10.1002/ana.24387

PMCID:: PMC4405474

Abstract Article PDF–555K

Select item 403304410.

Role of Integrin Alpha4 in Drug Resistance of Leukemia

Stephanie Shishido, Halvard Bönig, Yong-Mi Kim

Front Oncol. 2014; 4: 99. Published online 2014 May 23. doi: 10.3389/fonc.2014.00099

PMCID:: PMC4033044

Abstract Article PDF–1.2M

Select item 381189111.

The Membrane-Proximal KXGFFKR Motif of α-Integrin Mediates Chemoresistance

Chi-Chao Liu, Pascal Leclair, Shyong Quin Yap, Chinten James Lim

Mol Cell Biol. 2013 Nov; 33(21): 4334–4345. doi: 10.1128/MCB.00580-13

PMCID:: PMC3811891

Abstract Article PDF–1.8M

Select item 323773912.

Acquisition of resistance towards HYD1 correlates with a reduction in cleaved alpha 4 integrin expression and a compromised CAM-DR phenotype

Michael F. Emmons, Anthony W. Gebhard, Rajesh R. Nair, Rachid Baz, Mark McLaughlin, Anne E. Cress, Lori A. Hazlehurst

Mol Cancer Ther. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: Mol Cancer Ther. 2011 Dec; 10(12): 2257–2266. Published online 2011 Oct 6. doi: 10.1158/1535-7163.MCT-11-0149

PMCID:: PMC3237739

Abstract Article PDF–1.0M

Select item 190631513.

Adhesion to fibronectin via α4 integrin (CD49d) protects B cells from apoptosis induced by serum deprivation but not via IgM or Fas/Apo-1 receptors

M GARCIA-GILA, E M LÓPEZ-MARTIN, A GARCIA-PARDO

Clin Exp Immunol. 2002 Mar; 127(3): 455–462. doi: 10.1046/j.1365-2249.2002.01787.x

PMCID:: PMC1906315

Abstract Article PDF–120K

Select item 130369614.

FRET Detection of Cellular α₄-Integrin Conformational Activation

Alexandre Chigaev, Tione Buranda, Denise C. Dwyer, Eric R. Prossnitz, Larry A. Sklar

Biophys J. 2003 Dec; 85(6): 3951–3962. doi: 10.1016/S0006-3495(03)74809-7

PMCID:: PMC1303696

Abstract Article PDF–271K

Select item 126581715.

Integrin α4β1 Promotes Focal Adhesion Kinase-Independent Cell Motility via α4 Cytoplasmic Domain-Specific Activation of c-Src

Datsun A. Hsia, Ssang-Taek Lim, Joie A. Bernard-Trifilo, Satyajit K. Mitra, Sakae Tanaka, Jeroen den Hertog, Daniel N. Streblow, Dusko Ilic, Mark H. Ginsberg, David D. Schlaepfer

Mol Cell Biol. 2005 Nov; 25(21): 9700–9712. doi: 10.1128/MCB.25.21.9700-9712.2005