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Select item 109235181.

Molecular basis of JAK2 activation in erythropoietin receptor and pathogenic JAK2 signaling

Bobin George Abraham, Teemu Haikarainen, Joni Vuorio, Mykhailo Girych, Anniina T. Virtanen, Antti Kurttila, Christos Karathanasis, Mike Heilemann, Vivek Sharma, Ilpo Vattulainen, Olli Silvennoinen

Sci Adv. 2024 Mar 8; 10(10): eadl2097. Published online 2024 Mar 8. doi: 10.1126/sciadv.adl2097

PMCID:: PMC10923518

Abstract Article PDF–4.4M

Select item 108748632.

Proinflammatory phenotype of iPS cell-derived JAK2 V617F megakaryocytes induces fibrosis in 3D in vitro bone marrow niche

Niclas Flosdorf, Janik Böhnke, Marcelo A.S. de Toledo, Niklas Lutterbach, Vanesa Gómez Lerma, Martin Graßhoff, Kathrin Olschok, Siddharth Gupta, Vithurithra Tharmapalan, Susanne Schmitz, Katrin Götz, Herdit M. Schüler, Angela Maurer, Stephanie Sontag, Caroline Küstermann, Kristin Seré, Wolfgang Wagner, Ivan G. Costa, Tim H. Brümmendorf, Steffen Koschmieder, Nicolas Chatain, Miguel Castilho, Rebekka K. Schneider, Martin Zenke

Stem Cell Reports. 2024 Feb 13; 19(2): 224–238. Published online 2024 Jan 25. doi: 10.1016/j.stemcr.2023.12.011

PMCID:: PMC10874863

Abstract Article PDF–5.7M

Select item 108508163.

A newly identified 45‐kDa JAK2 variant with an altered kinase domain structure represents a novel mode of JAK2 kinase inhibitor resistance

Sivahari Prasad Gorantla, Tony Andreas Mueller, Corinna Albers‐Leischner, Martina Rudelius, Nikolas von Bubnoff, Justus Duyster

Mol Oncol. 2024 Feb; 18(2): 415–430. Published online 2023 Dec 20. doi: 10.1002/1878-0261.13566

PMCID:: PMC10850816

Abstract Article PDF–7.3M

Select item 108248734.

Identification and validation of the association of Janus kinase 2 mutations with the response to immune checkpoint inhibitor therapy

Peipei Chen, Junyu Long, Jiayang Zhang, Fucun Xie, Wei Wu, Zhuang Tian, Shuyang Zhang, Kang Yu

Inflamm Res. 2024; 73(2): 263–276. Published online 2024 Jan 10. doi: 10.1007/s00011-023-01833-w

PMCID:: PMC10824873

Abstract Article PDF–8.0M

Select item 107348275.

The impact of JAK2V617F mutation on Philadelphia-negative myeloproliferative neoplasms

Ezgi ŞAHİN, İpek YÖNAL-HİNDİLERDEN, Fehmi HİNDİLERDEN, Aynur ADAY, Meliha NALÇACI

Turk J Med Sci. 2022; 52(1): 150–165. Published online 2021 Sep 4. doi: 10.3906/sag-2103-247

PMCID:: PMC10734827

Abstract Article PDF–386K

Select item 107200686.

JAK2 as a surface marker for enrichment of human pluripotent stem cells-derived ventricular cardiomyocytes

Lee Chuen Liew, Boon Min Poh, Omer An, Beatrice Xuan Ho, Christina Ying Yan Lim, Jeremy Kah Sheng Pang, Leslie Y. Beh, Henry He Yang, Boon-Seng Soh

Stem Cell Res Ther. 2023; 14: 367. Published online 2023 Dec 13. doi: 10.1186/s13287-023-03610-2

PMCID:: PMC10720068

Abstract Article PDF–4.3M

Select item 107035677.

JAK2 V617F Mutation and Large Cerebral Artery Disease in Patients with Myeloproliferative Neoplasms

Naoki Oyama, Takanori Iwamoto, Keito Doyu, Saki Miyazato, Tomoko Okazaki, Seiko Yamada, Toshinori Kondo, Hideho Wada, Yoshiki Yagita

J Atheroscler Thromb. 2023 Dec 1; 30(12): 1917–1926. Published online 2023 Jun 21. doi: 10.5551/jat.64118

PMCID:: PMC10703567

Abstract Article PDF–239K

Select item 105610448.

JAK2V617F mutation is highly prevalent in patients with ischemic stroke: a case-control study

Marie Hvelplund Kristiansen, Lasse Kjær, Vibe Skov, Morten Kranker Larsen, Christina Ellervik, Hans Carl Hasselbalch, Troels Wienecke

Blood Adv. 2023 Oct 10; 7(19): 5825–5834. Published online 2023 Aug 2. doi: 10.1182/bloodadvances.2023010588

PMCID:: PMC10561044

Abstract Article PDF–311K

Select item 104762639.

JAK2 p.V617F Variants in Non-Blood DNA from Patients with Polycythemia Vera

Naoki Mori, Mari Ohwashi-Miyazaki, Kentaro Yoshinaga, Masayuki Shiseki, Junji Tanaka

Turk J Haematol. 2023 Sep; 40(3): 220–222. Published online 2023 Aug 31. doi: 10.4274/tjh.galenos.2023.2023-0159

PMCID:: PMC10476263

Article PDF–2.2M

Select item 1034975410.

JAK2V617F variant allele frequency, non-driver mutations, single-nucleotide variants and polycythemia vera outcome

Zuzanna Kanduła, Michał Janowski, Barbara Więckowska, Edyta Paczkowska, Krzysztof Lewandowski

J Cancer Res Clin Oncol. 2023; 149(8): 4789–4803. Published online 2022 Oct 15. doi: 10.1007/s00432-022-04327-0

PMCID:: PMC10349754

Abstract Article PDF–1.2M

Select item 1021786711.

Germline JAK2 E846D Substitution as the Cause of Erythrocytosis?

Nada Maaziz, Céline Garrec, Fabrice Airaud, Victor Bobée, Nathalie Contentin, Emilie Cayssials, Antoine Rimbert, Bernard Aral, Stéphane Bézieau, Betty Gardie, François Girodon

Genes (Basel) 2023 May; 14(5): 1066. Published online 2023 May 11. doi: 10.3390/genes14051066

PMCID:: PMC10217867

Abstract Article PDF–2.0M

Select item 1021359612.

Contributions of bone marrow monocytes/macrophages in myeloproliferative neoplasms with JAK2^V617F mutation

Wenjuan Fan, Weijie Cao, Jianxiang Shi, Fengcai Gao, Meng Wang, Linping Xu, Fang Wang, Yingmei Li, Rong Guo, Zhilei Bian, Wei Li, Zhongxing Jiang, Wang Ma

Ann Hematol. 2023; 102(7): 1745–1759. Published online 2023 May 26. doi: 10.1007/s00277-023-05284-5

PMCID:: PMC10213596

Abstract Article PDF–5.3M

Select item 1016331913.

JAK2^V617F allele burden in polycythemia vera: burden of proof

Alison R. Moliterno, Hannah Kaizer, Brandi N. Reeves

Blood. 2023 Apr 20; 141(16): 1934–1942. Published online 2023 Feb 9. doi: 10.1182/blood.2022017697

PMCID:: PMC10163319

Abstract Article

Select item 1000904714.

The Combination of JAK2V617F Allele Burden and WT1 Expression can Be Helpful in Distinguishing the Subtype of MPN Patients

Sanyun Wu, Ping Luo, Tuerxunayi Rouzi, Yalan Yu, Bei Xiong, Yingying Wang, Xuelan Zuo

Cancer Control. 2023 Jan-Dec; 30: 10732748231163648. Published online 2023 Mar 9. doi: 10.1177/10732748231163648

PMCID:: PMC10009047

Abstract Article PDF–834K

Select item 991131015.

Cell competition between wild-type and JAK2V617F mutant cells in a murine model of a myeloproliferative neoplasm

Melissa Castiglione, Haotian Zhang, Kenneth Kaushansky, Huichun Zhan

Exp Hematol. Author manuscript; available in PMC 2023 Feb 9.

Published in final edited form as: Exp Hematol. 2021 Aug; 100: 52–62. Published online 2021 Jun 19. doi: 10.1016/j.exphem.2021.06.003

PMCID:: PMC9911310

Abstract Article PDF–457K

Select item 966882216.

Increased risk of thrombosis in JAK2 V617F-positive patients with primary myelofibrosis and interaction of the mutation with the IPSS score

Tiziano Barbui, Arianna Ghirardi, Alessandra Carobbio, Arianna Masciulli, Greta Carioli, Alessandro Rambaldi, Maria Chiara Finazzi, Marta Bellini, Elisa Rumi, Daniele Vanni, Oscar Borsani, Francesco Passamonti, Barbara Mora, Marco Brociner, Paola Guglielmelli, Chiara Paoli, Alberto Alvarez-Larran, Ana Triguero, Marta Garrote, Helna Pettersson, Björn Andréasson, Giovanni Barosi, Alessandro Maria Vannucchi

Blood Cancer J. 2022 Nov; 12(11): 156. Published online 2022 Nov 16. doi: 10.1038/s41408-022-00743-0

PMCID:: PMC9668822

Article PDF–975K

Select item 960444717.

The Contribution of JAK2 46/1 Haplotype in the Predisposition to Myeloproliferative Neoplasms

Jhemerson Paes, George A. V. Silva, Andréa M. Tarragô, Lucivana P. de Souza Mourão

Int J Mol Sci. 2022 Oct; 23(20): 12582. Published online 2022 Oct 20. doi: 10.3390/ijms232012582

PMCID:: PMC9604447

Abstract Article PDF–4.4M

Select item 954421918.

JAK2 rs10974944 is associated with both V617F‐positive and negative myeloproliferative neoplasms in a Vietnamese population: A potential genetic marker

Nguyen Thy Ngoc, Bui Bich Hau, Nguyen Ba Vuong, Nguyen Thi Xuan

Mol Genet Genomic Med. 2022 Oct; 10(10): e2044. Published online 2022 Aug 22. doi: 10.1002/mgg3.2044

PMCID:: PMC9544219

Abstract Article PDF–601K

Select item 939618619.

Hematological relevance of JAK2 V617F and calreticulin mutations in Tunisian patients with essential thrombocythemia

Maroua Abdelghani, Haifa Hammami, Wiem Zidi, Hassiba Amouri, Hind Ben Hadj Othmen, Ahlem Farrah, Samia Menif

J Clin Lab Anal. 2022 Aug; 36(8): e24522. Published online 2022 Jun 26. doi: 10.1002/jcla.24522

PMCID:: PMC9396186

Abstract Article PDF–701K

Select item 933212420.

Transcriptional differences between JAK2-V617F and wild-type bone marrow cells in myeloproliferative neoplasm patients

Debra Van Egeren, Baransel Kamaz, Shichen Liu, Maximilian Nguyen, Christopher R. Reilly, Maria Kalyva, Daniel J. DeAngelo, Ilene Galinsky, Martha Wadleigh, Eric S. Winer, Marlise R. Luskin, Richard M. Stone, Jacqueline S. Garcia, Gabriela S. Hobbs, Franziska Michor, Isidro Cortes-Ciriano, Ann Mullally, Sahand Hormoz

Exp Hematol. Author manuscript; available in PMC 2023 Mar 1.

Published in final edited form as: Exp Hematol. 2022 Mar; 107: 14–19. Published online 2021 Dec 15. doi: 10.1016/j.exphem.2021.12.364

PMCID:: PMC9332124

Abstract Article PDF–1.0M

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Homo sapiens IL-24 splice variant delE5 mRNA, complete cds, alternatively splice...
Homo sapiens IL-24 splice variant delE5 mRNA, complete cds, alternatively spliced
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