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Select item 70995091.

Juvenile OLFM4-null mice are protected from sepsis

Julie E. Stark, Amy M. Opoka, Jaya Mallela, Prasad Devarajan, Qing Ma, Nick C. Levinsky, Keith F. Stringer, Hector R. Wong, Matthew N. Alder

Am J Physiol Renal Physiol. 2020 Mar 1; 318(3): F809–F816. Published online 2020 Feb 18. doi: 10.1152/ajprenal.00443.2019

PMCID:: PMC7099509

Abstract Article

Select item 68940512.

The olfactomedin-4 positive neutrophil has a role in murine intestinal ischemia/reperfusion injury

Nick C. Levinsky, Jaya Mallela, Amy M. Opoka, Kelli Harmon, Hannah V. Lewis, Basilia Zingarelli, Hector R. Wong, Matthew N. Alder

FASEB J. 2019 Dec; 33(12): 13660–13668. Published online 2019 Nov 25. doi: 10.1096/fj.201901231R

PMCID:: PMC6894051

Abstract Article

Select item 66618923.

Olfactomedin 4 marks a subset of neutrophils in mice

Matthew N Alder, Jaya Mallela, Amy M Opoka, Patrick Lahni, David A Hildeman, Hector R Wong

Innate Immun. 2019 Jan; 25(1): 22–33. Published online 2018 Dec 11. doi: 10.1177/1753425918817611

PMCID:: PMC6661892

Abstract Article PDF–1.0M

Select item 60982264.

Olfactomedin 4 Deletion Improves Male Mouse Glucose Intolerance and Insulin Resistance Induced by a High-Fat Diet

Wenli Liu, Wulin Aerbajinai, Hongzhen Li, Yueqin Liu, Oksana Gavrilova, Shalini Jain, Griffin P Rodgers

Endocrinology. 2018 Sep; 159(9): 3235–3244. Published online 2018 Jul 19. doi: 10.1210/en.2018-00451

PMCID:: PMC6098226

Abstract Article

Select item 101580325.

Olfactomedin-4 deletion exacerbates DSS-induced colitis through a matrix metalloproteinase-9-dependent mechanism

Xinyu Wang, Shenghui Chen, Jinghua Wang, Yishu Chen, Yanjun Guo, Qinqiu Wang, Zhening Liu, Hang Zeng, Chengfu Xu

Int J Biol Sci. 2023; 19(7): 2150–2166. Published online 2023 Apr 9. doi: 10.7150/ijbs.80441

PMCID:: PMC10158032

Abstract Article PDF–10M

Select item 72393286.

T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation

Ya-Yuan Fu, Anastasiya Egorova, Catherine Sobieski, Jason Kuttiyara, Marco Calafiore, Shuichiro Takashima, Hans Clevers, Alan M. Hanash

Immunity. Author manuscript; available in PMC 2020 Jul 16.

Published in final edited form as: Immunity. 2019 Jul 16; 51(1): 90–103.e3. Published online 2019 Jul 2. doi: 10.1016/j.immuni.2019.06.003

PMCID:: PMC7239328

Abstract Article PDF–3.3M

Select item 62306837.

Olfactomedin 4 contributes to hydrogen peroxide-induced NADPH oxidase activation and apoptosis in mouse neutrophils

Wenli Liu, Yueqin Liu, Hongzhen Li, Griffin P. Rodgers

Am J Physiol Cell Physiol. 2018 Oct 1; 315(4): C494–C501. Published online 2018 Jun 27. doi: 10.1152/ajpcell.00336.2017

PMCID:: PMC6230683

Abstract Article

Select item 46522038.

Olfactomedin 4 deficiency promotes prostate neoplastic progression and is associated with upregulation of the hedgehog-signaling pathway

Hongzhen Li, Wenli Liu, Weiping Chen, Jianqiong Zhu, Chu-Xia Deng, Griffin P. Rodgers

Sci Rep. 2015; 5: 16974. Published online 2015 Nov 19. doi: 10.1038/srep16974

PMCID:: PMC4652203

Abstract Article PDF–2.3M

Select item 41755429.

Robust Cre-Mediated Recombination in Small Intestinal Stem Cells Utilizing the Olfm4 Locus

Jurian Schuijers, Laurens G. van der Flier, Johan van Es, Hans Clevers

Stem Cell Reports. 2014 Aug 12; 3(2): 234–241. Published online 2014 Jun 26. doi: 10.1016/j.stemcr.2014.05.018

PMCID:: PMC4175542

Abstract Article PDF–2.6M

Select item 388782910.

Olfactomedin 4 Suppresses Tumor Growth and Metastasis of Mouse Melanoma Cells through Downregulation of Integrin and MMP Genes

Key Sun Park, Kee Kwang Kim, Zheng-Hao Piao, Mi Kyung Kim, Hyun Jean Lee, Yong Chan Kim, Ki Sung Lee, Jeung-Hoon Lee, Kyoon Eon Kim

Mol Cells. 2012 Dec 31; 34(6): 555–561. Published online 2012 Nov 15. doi: 10.1007/s10059-012-0251-7

PMCID:: PMC3887829

Abstract Article PDF–1.3M

Select item 375425811.

Olfm4 deletion enhances defense against Staphylococcus aureus in chronic granulomatous disease

Wenli Liu, Ming Yan, Janyce A. Sugui, Hongzhen Li, Chengfu Xu, Jungsoo Joo, Kyung J. Kwon-Chung, William G. Coleman, Griffin P. Rodgers

J Clin Invest. 2013 Sep 3; 123(9): 3751–3755. Published online 2013 Aug 1. doi: 10.1172/JCI68453

PMCID:: PMC3754258

Abstract Article PDF–792K

Select item 629411212.

Genome Toxicity and Impaired Stem Cell Function after Conditional Activation of CreER^T2 in the Intestine

Natacha Bohin, Elizabeth A. Carlson, Linda C. Samuelson

Stem Cell Reports. 2018 Dec 11; 11(6): 1337–1346. Published online 2018 Nov 15. doi: 10.1016/j.stemcr.2018.10.014

PMCID:: PMC6294112

Abstract Article PDF–2.9M

Select item 505704313.

Olfactomedin 4 deletion induces colon adenocarcinoma in Apc^Min/+ mice

W Liu, H Li, S-H Hong, G P Piszczek, W Chen, G P Rodgers

Oncogene. 2016 Oct 6; 35(40): 5237–5247. Published online 2016 Mar 14. doi: 10.1038/onc.2016.58

PMCID:: PMC5057043

Abstract Article PDF–3.9M

Select item 342437914.

Olfactomedin 4 Inhibits Cathepsin C-Mediated Protease Activities, Thereby Modulating Neutrophil Killing of Staphylococcus aureus and Escherichia coli in Mice

Wenli Liu, Ming Yan, Yueqin Liu, Kenneth R. McLeish, William G. Coleman, Jr., Griffin P. Rodgers

J Immunol. 2012 Sep 1; 189(5): 2460–2467. Published online 2012 Jul 27. doi: 10.4049/jimmunol.1103179

PMCID:: PMC3424379

Abstract Article PDF–793K

Select item 1048042615.

A tissue-intrinsic IL-33/EGF circuit promotes epithelial regeneration after intestinal injury

Marco Calafiore, Ya-Yuan Fu, Paola Vinci, Viktor Arnhold, Winston Y. Chang, Suze A. Jansen, Anastasiya Egorova, Shuichiro Takashima, Jason Kuttiyara, Takahiro Ito, Jonathan Serody, Susumu Nakae, Heth Turnquist, Johan van Es, Hans Clevers, Caroline A. Lindemans, Bruce R. Blazar, Alan M. Hanash

Nat Commun. 2023; 14: 5411. Published online 2023 Sep 5. doi: 10.1038/s41467-023-40993-5

PMCID:: PMC10480426

Abstract Article PDF–3.2M

Select item 882649316.

CDC42 controlled apical-basal polarity regulates intestinal stem cell to transit amplifying cell fate transition via YAP-EGF-mTOR signaling

Zheng Zhang, Feng Zhang, Ashley Kuenzi Davis, Mei Xin, Gerd Walz, Weidong Tian, Yi Zheng

Cell Rep. Author manuscript; available in PMC 2022 Feb 9.

Published in final edited form as: Cell Rep. 2022 Jan 11; 38(2): 110009. doi: 10.1016/j.celrep.2021.110009

PMCID:: PMC8826493

Abstract Article PDF–3.6M

Select item 640321417.

Znhit1 controls intestinal stem cell maintenance by regulating H2A.Z incorporation

Bing Zhao, Ying Chen, Ning Jiang, Li Yang, Shenfei Sun, Yan Zhang, Zengqi Wen, Lorraine Ray, Han Liu, Guoli Hou, Xinhua Lin

Nat Commun. 2019; 10: 1071. Published online 2019 Mar 6. doi: 10.1038/s41467-019-09060-w

PMCID:: PMC6403214

Abstract Article PDF–2.7M

Select item 449199418.

Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium

Katja Horvay, Thierry Jardé, Franca Casagranda, Victoria M Perreau, Katharina Haigh, Christian M Nefzger, Reyhan Akhtar, Thomas Gridley, Geert Berx, Jody J Haigh, Nick Barker, Jose M Polo, Gary R Hime, Helen E Abud

EMBO J. 2015 May 12; 34(10): 1319–1335. Published online 2015 Mar 10. doi: 10.15252/embj.201490881