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Items: 1 to 20 of 304

1.
Evaluation of the role of KPNA2 mutations in breast cancer prognosis using bioinformatics datasets
Layla Alnoumas, Lisa van den Driest, Zoe Apczynski, Alison Lannigan, Caroline H. Johnson, Nicholas J. W. Rattray, Zahra Rattray
BMC Cancer. 2022; 22: 874. Published online 2022 Aug 10. doi: 10.1186/s12885-022-09969-4
PMCID:
PMC9364282
AbstractArticlePDF–3.3M
2.
MiR-101-3p Suppresses Progression of Cervical Squamous Cell Carcinoma by Targeting and Down-Regulating KPNA2
Hong Wang, Rongxin Xiao, Biao Yang
Technol Cancer Res Treat. 2021; 20: 15330338211055948. Published online 2021 Nov 24. doi: 10.1177/15330338211055948
PMCID:
PMC8647218
AbstractArticlePDF–1.7M
3.
KPNA2 promotes renal cell carcinoma proliferation and metastasis via NPM
Song Zheng, Xiaofan Li, Ting Deng, Rong Liu, Junjie Bai, Teng Zuo, Yinan Guo, Jianhui Chen
J Cell Mol Med. 2021 Oct; 25(19): 9255–9267. Published online 2021 Sep 1. doi: 10.1111/jcmm.16846
PMCID:
PMC8500977
AbstractArticlePDF–1.9M
4.
Increased expression of KPNA2 predicts unfavorable prognosis in ovarian cancer patients, possibly by targeting KIF4A signaling
Xiangrong Cui, Honghong Wang, Xueqing Wu, Kai Huo, Xuan Jing
J Ovarian Res. 2021; 14: 71. Published online 2021 May 25. doi: 10.1186/s13048-021-00818-9
PMCID:
PMC8152344
AbstractArticlePDF–5.0M
5.
Zika virus NS2A protein induces the degradation of KPNA2 (karyopherin subunit alpha 2) via chaperone-mediated autophagy
Jia He, Liping Yang, Peixi Chang, Shixing Yang, Shaoli Lin, Qiyi Tang, Xinping Wang, Yan-Jin Zhang
Autophagy. 2020; 16(12): 2238–2251. Published online 2020 Sep 28. doi: 10.1080/15548627.2020.1823122
PMCID:
PMC7751636
AbstractArticlePDF–1.6M
6.
Karyopherin α-2 Mediates MDC1 Nuclear Import through a Functional Nuclear Localization Signal in the tBRCT Domain of MDC1
Kamalakannan Radhakrishnan, Seon-Joo Park, Seok Won Kim, Gurusamy Hariharasudhan, Seo-Yeon Jeong, In Youb Chang, Jung-Hee Lee
Int J Mol Sci. 2020 Apr; 21(7): 2650. Published online 2020 Apr 10. doi: 10.3390/ijms21072650
PMCID:
PMC7177644
AbstractArticlePDF–1.9M
7.
Aptamers that bind specifically to human KPNA2 (importin-α1) and efficiently interfere with nuclear transport
Noriko Yasuhara, Penmetcha K.R. Kumar
J Biochem. 2016 Nov; 160(5): 259–268. Published online 2016 May 6. doi: 10.1093/jb/mvw032
PMCID:
PMC7110145
AbstractArticlePDF–855K
8.
Overexpression of Karyopherin Subunit alpha 2 (KPNA2) Predicts Unfavorable Prognosis and Promotes Bladder Cancer Tumorigenicity via the P53 Pathway
Changlong Shi, Li Sun, Shaozhuang Liu, Enchong Zhang, Yongsheng Song
Med Sci Monit. 2020; 26: e921087-1–e921087-13. Prepublished online 2020 Jan 22. Published online 2020 Mar 9. doi: 10.12659/MSM.921087
PMCID:
PMC7081662
AbstractArticlePDF–2.8M
9.
Overexpression of karyopherin-α2 in cholangiocarcinoma correlates with poor prognosis and gemcitabine sensitivity via nuclear translocation of DNA repair proteins
Mariko Tsukagoshi, Kenichiro Araki, Takehiko Yokobori, Bolag Altan, Hideki Suzuki, Norio Kubo, Akira Watanabe, Norihiro Ishii, Yasuo Hosouchi, Masahiko Nishiyama, Ken Shirabe, Hiroyuki Kuwano
Oncotarget. 2017 Jun 27; 8(26): 42159–42172. Published online 2017 Feb 2. doi: 10.18632/oncotarget.15020
PMCID:
PMC5522057
AbstractArticlePDF–2.4M
10.
Silencing of karyopherin α2 inhibits cell growth and survival in human hepatocellular carcinoma
Yunfeng Yang, Jian Guo, Yuxia Hao, Fuhua Wang, Fengxia Li, Shaomin Shuang, Junping Wang
Oncotarget. 2017 May 30; 8(22): 36289–36304. Published online 2017 Mar 31. doi: 10.18632/oncotarget.16749
PMCID:
PMC5482655
AbstractArticlePDF–7.9M
11.
Prognostic value of increased KPNA2 expression in some solid tumors: A systematic review and meta-analysis
Li-Na Zhou, Yue Tan, Ping Li, Ping Zeng, Min-Bin Chen, Ye Tian, Ya-Qun Zhu
Oncotarget. 2017 Jan 3; 8(1): 303–314. Published online 2016 Dec 10. doi: 10.18632/oncotarget.13863
PMCID:
PMC5352121
AbstractArticlePDF–3.0M
12.
Low cytoplasmic and nuclear KPNA2 expression in radiotherapy-treated head and neck squamous cell cancer is associated with an adverse outcome
Pia B Erben, Kathrin Brunner, Markus Hecht, Marlen Haderlein, Maike Büttner-Herold, Abbas Agaimy, Rainer Fietkau, Arndt Hartmann, Luitpold V Distel
Int J Clin Exp Pathol. 2015; 8(12): 15814–15824. Published online 2015 Dec 1.
PMCID:
PMC4730065
AbstractArticlePDF–3.3M
13.
Karyopherin alpha 2 is a novel prognostic marker and a potential therapeutic target for colon cancer
Yu Zhang, Meng Zhang, Fudong Yu, Su Lu, Huimin Sun, Huamei Tang, Zhihai Peng
J Exp Clin Cancer Res. 2015; 34: 145. Published online 2015 Dec 1. doi: 10.1186/s13046-015-0261-3
PMCID:
PMC4665890
AbstractArticlePDF–2.1M
14.
KPNA2 is a nuclear export protein that contributes to aberrant localisation of key proteins and poor prognosis of breast cancer
A T Alshareeda, O H Negm, A R Green, C C Nolan, P Tighe, N Albarakati, R Sultana, S Madhusudan, I O Ellis, E A Rakha
Br J Cancer. 2015 Jun 9; 112(12): 1929–1937. Published online 2015 May 19. doi: 10.1038/bjc.2015.165
PMCID:
PMC4580386
AbstractArticlePDF–1.2M
15.
Classical Nuclear Localization Signals: Definition, Function, and Interaction with Importin α
Allison Lange, Ryan E. Mills, Christopher J. Lange, Murray Stewart, Scott E. Devine, Anita H. Corbett
J Biol Chem. Author manuscript; available in PMC 2015 Jul 15.
Published in final edited form as: J Biol Chem. 2007 Feb 23; 282(8): 5101–5105. Published online 2006 Dec 14. doi: 10.1074/jbc.R600026200
PMCID:
PMC4502416
AbstractArticlePDF–554K
16.
High expression of KPNA2 defines poor prognosis in patients with upper tract urothelial carcinoma treated with radical nephroureterectomy
Bentao Shi, Boxing Su, Dong Fang, Yuan Tang, Gengyan Xiong, Zhongqiang Guo, Qun He, Xinyu Yang, Wei Zhao, Yinglu Guo, Xuesong Li, Liqun Zhou
BMC Cancer. 2015; 15: 380. Published online 2015 May 9. doi: 10.1186/s12885-015-1369-8
PMCID:
PMC4432830
AbstractArticlePDF–1.1M
17.
Crystal Structure of Human Importin-α1 (Rch1), Revealing a Potential Autoinhibition Mode Involving Homodimerization
Hideyuki Miyatake, Akira Sanjoh, Satoru Unzai, Go Matsuda, Yuko Tatsumi, Yoichi Miyamoto, Naoshi Dohmae, Yoko Aida
PLoS One. 2015; 10(2): e0115995. Published online 2015 Feb 6. doi: 10.1371/journal.pone.0115995
PMCID:
PMC4319847
AbstractArticlePDF–6.1M
18.
Karyopherin Alpha2 Is Essential for rRNA Transcription and Protein Synthesis in Proliferative Keratinocytes
Noriko Umegaki-Arao, Katsuto Tamai, Keisuke Nimura, Satoshi Serada, Tetsuji Naka, Hajime Nakano, Ichiro Katayama
PLoS One. 2013; 8(10): e76416. Published online 2013 Oct 3. doi: 10.1371/journal.pone.0076416
PMCID:
PMC3789663
AbstractArticlePDF–2.5M
19.
Molecular Profiling of Multiple Human Cancers Defines an Inflammatory Cancer-Associated Molecular Pattern and Uncovers KPNA2 as a Uniform Poor Prognostic Cancer Marker
Saleh M. Rachidi, Tingting Qin, Shaoli Sun, W. Jim Zheng, Zihai Li
PLoS One. 2013; 8(3): e57911. Published online 2013 Mar 25. doi: 10.1371/journal.pone.0057911
Correction in:
PLoS One. 2014; 9(1): 10.1371/annotation/a8159928-d073-4b5b-8a50-c68c95b78681.
PMCID:
PMC3607594
AbstractArticlePDF–2.4M
20.
Quantitative Proteomics Reveals Regulation of Karyopherin Subunit Alpha-2 (KPNA2) and Its Potential Novel Cargo Proteins in Nonsmall Cell Lung Cancer
Chun-I Wang, Kun-Yi Chien, Chih-Liang Wang, Hao-Ping Liu, Chia-Chen Cheng, Yu-Sun Chang, Jau-Song Yu, Chia-Jung Yu
Mol Cell Proteomics. 2012 Nov; 11(11): 1105–1122. Published online 2012 Jul 25. doi: 10.1074/mcp.M111.016592
PMCID:
PMC3494185
AbstractArticlePDF–2.8M

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