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Items: 1 to 20 of 83

1.
Overexpression of laminin-5 gamma-2 promotes tumorigenesis of pancreatic ductal adenocarcinoma through EGFR/ERK1/2/AKT/mTOR cascade
Anuradha Kirtonia, Amit Kumar Pandey, Balaji Ramachandran, Durga Prasad Mishra, David W. Dawson, Gautam Sethi, Trivadi S. Ganesan, H. Phillip Koeffler, Manoj Garg
Cell Mol Life Sci. 2022 Jul; 79(7): 362. Published online 2022 Jun 14. doi: 10.1007/s00018-022-04392-1
PMCID:
PMC11073089
AbstractArticlePDF–3.0M
2.
LAMC2 regulates the proliferation, invasion, and metastasis of gastric cancer via PI3K/Akt signaling pathway
Lulu Cheng, Xiaofei Li, Wenhui Dong, Jing Yang, Pengmei Li, Xihui Qiang, Jiajun Yin, Lianyi Guo
J Cancer Res Clin Oncol. 2024; 150(5): 230. Published online 2024 May 4. doi: 10.1007/s00432-024-05720-7
PMCID:
PMC11069487
AbstractArticlePDF–2.9M
3.
LAMC2 promotes EGFR cell membrane localization and acts as a novel biomarker for tyrosine kinase inhibitors (TKIs) sensitivity in lung cancer
Dongdong Tong, Xiaofei Wang, Liying Liu, Ting Wen, QiaoYi Chen, Chen Huang
Cancer Gene Ther. 2023; 30(11): 1498–1512. Published online 2023 Aug 4. doi: 10.1038/s41417-023-00654-7
PMCID:
PMC10645587
AbstractArticlePDF–7.1M
4.
LAMC2 as a prognostic biomarker in human cancer: a systematic review and meta-analysis
Tao Fu, Jun-Xia Liu, Juan Xie, Zhen Gao, Zhenshan Yang
BMJ Open. 2022; 12(11): e063682. Published online 2022 Nov 16. doi: 10.1136/bmjopen-2022-063682
PMCID:
PMC9677043
AbstractArticlePDF–2.4M
5.
LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer
Donatella Delle Cave, Silvia Buonaiuto, Bruno Sainz, Jr, Marco Fantuz, Maria Mangini, Alessandro Carrer, Annalisa Di Domenico, Tea Teresa Iavazzo, Gennaro Andolfi, Carme Cortina, Marta Sevillano, Christopher Heeschen, Vincenza Colonna, Marco Corona, Antonio Cucciardi, Martina Di Guida, Eduard Batlle, Annachiara De Luca, Enza Lonardo
J Exp Clin Cancer Res. 2022; 41: 315. Published online 2022 Oct 26. doi: 10.1186/s13046-022-02516-w
PMCID:
PMC9609288
AbstractArticlePDF–2.9M
6.
Orchestrated expression of vasculogenic mimicry and laminin‐5γ2 is an independent prognostic marker in oral squamous cell carcinoma
Depanwita Saha, Debarpan Mitra, Neyaz Alam, Sagar Sen, Saunak Mitra Mustafi, Syamsundar Mandal, Biswanath Majumder, Nabendu Murmu
Int J Exp Pathol. 2022 Apr; 103(2): 54–64. Published online 2022 Feb 16. doi: 10.1111/iep.12430
PMCID:
PMC8961501
AbstractArticlePDF–1.1M
7.
LAMC2 promotes cancer progression and gemcitabine resistance through modulation of EMT and ATP-binding cassette transporters in pancreatic ductal adenocarcinoma
Yasuyuki Okada, Naoki Takahashi, Tetsuji Takayama, Ajay Goel
Carcinogenesis. 2021 Apr; 42(4): 546–556. Published online 2021 Feb 24. doi: 10.1093/carcin/bgab011
PMCID:
PMC8086766
AbstractArticlePDF–5.7M
8.
Identification of LAMC2 as a prognostic and predictive biomarker for determining response to gemcitabine-based therapy in pancreatic ductal adenocarcinoma
Yasuyuki Okada, Satoshi Nishiwada, Kensuke Yamamura, Masayuki Sho, Hideo Baba, Tetsuji Takayama, Ajay Goel
Eur J Cancer. Author manuscript; available in PMC 2022 Mar 1.
Published in final edited form as: Eur J Cancer. 2021 Mar; 146: 125–134. Published online 2021 Feb 16. doi: 10.1016/j.ejca.2020.12.031
PMCID:
PMC7940597
AbstractArticlePDF–949K
9.
Urinary laminin‐γ2 is a novel biomarker of non‐muscle invasive urothelial carcinoma
Masayuki Kamada, Naohiko Koshikawa, Tomoko Minegishi, Chiaki Kawada, Takashi Karashima, Taro Shuin, Motoharu Seiki
Cancer Sci. 2015 Dec; 106(12): 1730–1737. Published online 2015 Nov 6. doi: 10.1111/cas.12832
PMCID:
PMC4714663
AbstractArticlePDF–1.5M
10.
Amino-terminal fragments of laminin γ2 chain retract vascular endothelial cells and increase vascular permeability
Hiroki Sato, Jun Oyanagi, Eriko Komiya, Takashi Ogawa, Shouichi Higashi, Kaoru Miyazaki
Cancer Sci. 2014 Feb; 105(2): 168–175. Published online 2014 Jan 7. doi: 10.1111/cas.12323
PMCID:
PMC4317827
AbstractArticlePDF–1.7M
11.
Expression of the gamma 2 chain of laminin-332 in eutopic and ectopic endometrium of patients with endometriosis
Rosella Locci, Michelle Nisolle, Stefano Angioni, Jean-Michel Foidart, Carine Munaut
Reprod Biol Endocrinol. 2013; 11: 94. Published online 2013 Sep 26. doi: 10.1186/1477-7827-11-94
PMCID:
PMC3849601
AbstractArticlePDF–3.6M
12.
Laminin, gamma 2 (LAMC2): A Promising New Putative Pancreatic Cancer Biomarker Identified by Proteomic Analysis of Pancreatic Adenocarcinoma Tissues
Hari Kosanam, Ioannis Prassas, Caitlin C. Chrystoja, Ireena Soleas, Alison Chan, Apostolos Dimitromanolakis, Ivan M. Blasutig, Felix Rückert, Robert Gruetzmann, Christian Pilarsky, Masato Maekawa, Randall Brand, Eleftherios P. Diamandis
Mol Cell Proteomics. 2013 Oct; 12(10): 2820–2832. Published online 2013 Jun 24. doi: 10.1074/mcp.M112.023507
PMCID:
PMC3790293
AbstractArticlePDF–1.5M
13.
Profiling Bladder Cancer Organ Site-Specific Metastasis Identifies LAMC2 as a Novel Biomarker of Hematogenous Dissemination
Steven Christopher Smith, Brian Nicholson, Matthew Nitz, Henry F. Frierson, Jr, Mark Smolkin, Garret Hampton, Wael El-Rifai, Dan Theodorescu
Am J Pathol. 2009 Feb; 174(2): 371–379. doi: 10.2353/ajpath.2009.080538
PMCID:
PMC2630547
AbstractArticlePDF–925K
14.
A truncated laminin chain homologous to the B2 chain: structure, spatial expression, and chromosomal assignment
J Cell Biol. 1992 Nov 1; 119(3): 679–693. doi: 10.1083/jcb.119.3.679
PMCID:
PMC2289671
SummaryPDF–4.0M
15.
Converging signals synergistically activate the LAMC2 promoter and lead to accumulation of the laminin gamma 2 chain in human colon carcinoma cells.
Jørgen Olsen, Lene T Kirkeby, Marianne M Brorsson, Sally Dabelsteen, Jesper T Troelsen, Randi Bordoy, Kirsten Fenger, Lars-Inge Larsson, Patricia Simon-Assmann
Biochem J. 2003 Apr 1; 371(Pt 1): 211–221. doi: 10.1042/BJ20021454
PMCID:
PMC1223269
SummaryPDF–323K
16.
Involvement of activator protein 1 complexes in the epithelium-specific activation of the laminin gamma2-chain gene promoter by hepatocyte growth factor (scatter factor).
J Olsen, O Lefebvre, C Fritsch, J T Troelsen, V Orian-Rousseau, M Kedinger, P Simon-Assmann
Biochem J. 2000 Apr 15; 347(Pt 2): 407–417. doi: 10.1042/0264-6021:3470407
PMCID:
PMC1220973
SummaryPDF–373K
17.
A large cell-adhesive scatter factor secreted by human gastric carcinoma cells.
K Miyazaki, Y Kikkawa, A Nakamura, H Yasumitsu, M Umeda
Proc Natl Acad Sci U S A. 1993 Dec 15; 90(24): 11767–11771. doi: 10.1073/pnas.90.24.11767
PMCID:
PMC48065
SummaryPage BrowsePDF–1.5M
18.
Extracellular matrix marker LAMC2 targets ZEB1 to promote TNBC malignancy via up-regulating CD44/STAT3 signaling pathway
Ding Wang, Kailibinuer Keyoumu, Rongji Yu, Doudou Wen, Hao Jiang, Xinchun Liu, Xiaotang Di, Shubing Zhang
Mol Med. 2024; 30: 61. Published online 2024 May 17. doi: 10.1186/s10020-024-00827-6
PMCID:
PMC11100204
AbstractArticlePDF–9.3M
19.
Novel LAMC2 fusion protein has tumor‐promoting properties in ovarian carcinoma
Hoshino Daisuke, Hisamori Kato, Kazuhiro Fukumura, Akila Mayeda, Yohei Miyagi, Motoharu Seiki, Naohiko Koshikawa
Cancer Sci. 2021 Dec; 112(12): 4957–4967. Published online 2021 Nov 5. doi: 10.1111/cas.15149
PMCID:
PMC8645749
AbstractArticlePDF–1.0M
20.
hsa-miR-5580-3p inhibits oral cancer cell viability, proliferation and migration by suppressing LAMC2
Rong Fang, Qian Lu, Bo Xu
Mol Med Rep. 2021 Jun; 23(6): 453. Published online 2021 Apr 15. doi: 10.3892/mmr.2021.12092
PMCID:
PMC8072311
AbstractArticlePDF–10M

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