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Select item 72549921.

Investigation of the role and mechanism of ARHGAP5-mediated colorectal cancer metastasis

Tian Tian, Zhan-Hong Chen, Zongheng Zheng, Yubo Liu, Qi Zhao, Yuying Liu, Huijun Qiu, Qian Long, Miao Chen, Liren Li, Fangyun Xie, Guangyu Luo, Xiaojun Wu, Wuguo Deng

Theranostics. 2020; 10(13): 5998–6010. Published online 2020 May 1. doi: 10.7150/thno.43427

PMCID:: PMC7254992

Abstract Article PDF–4.0M

Select item 38839222.

Downregulation of miR-486-5p contributes to tumor progression and metastasis by targeting protumorigenic ARHGAP5 in lung cancer

J Wang, X Tian, R Han, X Zhang, X Wang, H Shen, L Xue, Y Liu, X Yan, J Shen, K Mannoor, J Deepak, JM Donahue, SA Stass, L Xing, F Jiang

Oncogene. Author manuscript; available in PMC 2014 Aug 27.

Published in final edited form as: Oncogene. 2014 Feb 27; 33(9): 1181–1189. Published online 2013 Mar 11. doi: 10.1038/onc.2013.42

PMCID:: PMC3883922

Abstract Article PDF–3.6M

Select item 21736583.

p190RhoGAP is cell cycle regulated and affects cytokinesis

Ling Su, Joyce M. Agati, Sarah J. Parsons

J Cell Biol. 2003 Nov 10; 163(3): 571–582. doi: 10.1083/jcb.200308007

PMCID:: PMC2173658

Abstract Article PDF–588K

Select item 3592514.

p190 RhoGAP, the major RasGAP-associated protein, binds GTP directly.

R Foster, K Q Hu, D A Shaywitz, J Settleman

Mol Cell Biol. 1994 Nov; 14(11): 7173–7181. doi: 10.1128/mcb.14.11.7173

PMCID:: PMC359251

Summary Page Browse PDF–2.2M

Select item 100674385.

Circular RNA ARHGAP5 inhibits cisplatin resistance in cervical squamous cell carcinoma by interacting with AUF1

Sisi Deng, Lili Qian, Luwen Liu, Hanyuan Liu, Zhihao Xu, Yujie Liu, Yingying Wang, Liang Chen, Ying Zhou

Cancer Sci. 2023 Apr; 114(4): 1582–1595. Published online 2023 Feb 2. doi: 10.1111/cas.15723

PMCID:: PMC10067438

Abstract Article PDF–6.1M

Select item 97309386.

The p190 RhoGAPs, ARHGAP35 and ARHGAP5, are Implicated in GnRH Neuronal Development: Evidence from Patients with Idiopathic Hypogonadotropic Hypogonadism, Zebrafish and in vitro GAP Activity Assay

Margaret F. Lippincott, Wanxue Xu, Abigail A. Smith, Xinyu Miao, Agathe Lafont, Omar Shennib, Gordon J. Farley, Riwa Sabbagh, Angela Delaney, Maria Stamou, Lacey Plummer, Kathryn Salnikov, Neoklis A. Georgopoulos, Veronica Mericq, Richard Quinton, Frederic Tran Mau-Them, Sophie Nambot, Asma Hamad, Helen Brittain, Rebecca S. Tooze, Eduardo Calpena, Andrew O.M. Wilkie, Marjolaine Willems, William F. Crowley, Ravikumar Balasubramanian, Nathalie Lamarche-Vane, Erica E. Davis, Stephanie B. Seminara

Genet Med. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: Genet Med. 2022 Dec; 24(12): 2501–2515. Published online 2022 Sep 30. doi: 10.1016/j.gim.2022.08.025

PMCID:: PMC9730938

Abstract Article PDF–1.2M

Select item 61551577.

SIRT1 suppresses the migration and invasion of gastric cancer by regulating ARHGAP5 expression

Guoying Dong, Bo Wang, Yifei An, Juan Li, Xin Wang, Jihui Jia, Qing Yang

Cell Death Dis. 2018 Oct; 9(10): 977. Published online 2018 Sep 24. doi: 10.1038/s41419-018-1033-8

PMCID:: PMC6155157

Abstract Article PDF–5.0M

Select item 36899718.

Interaction of p190RhoGAP with C-terminal Domain of p120-catenin Modulates Endothelial Cytoskeleton and Permeability

Noureddine Zebda, Yufeng Tian, Xinyong Tian, Grzegorz Gawlak, Katherine Higginbotham, Albert B. Reynolds, Anna A. Birukova, Konstantin G. Birukov

J Biol Chem. 2013 Jun 21; 288(25): 18290–18299. Published online 2013 May 7. doi: 10.1074/jbc.M112.432757

PMCID:: PMC3689971

Abstract Article PDF–2.3M

Select item 36677229.

RhoA is down-regulated at cell–cell contacts via p190RhoGAP-B in response to tensional homeostasis

Suzanne M. Ponik, Steven M. Trier, Michele A. Wozniak, Kevin W. Eliceiri, Patricia J. Keely

Mol Biol Cell. 2013 Jun 1; 24(11): 1688–1699. doi: 10.1091/mbc.E12-05-0386

PMCID:: PMC3667722

Abstract Article PDF–1.4M

Select item 217515210.

Role of P120 Ras-Gap in Directed Cell Movement

Sarang V. Kulkarni, Gerald Gish, Peter van der Geer, Mark Henkemeyer, Tony Pawson

J Cell Biol. 2000 Apr 17; 149(2): 457–470. doi: 10.1083/jcb.149.2.457

PMCID:: PMC2175152

Abstract Article PDF–1.0M

Select item 453700611.

MiR-744 functions as a proto-oncogene in nasopharyngeal carcinoma progression and metastasis via transcriptional control of ARHGAP5

Yuan Fang, Xiaoxia Zhu, Jian Wang, Na Li, Dianhe Li, Nazmus Sakib, Zhou Sha, Wen Song

Oncotarget. 2015 May 30; 6(15): 13164–13175. Published online 2015 Apr 18. doi: 10.18632/oncotarget.3754

PMCID:: PMC4537006

Abstract Article PDF–6.9M

Select item 278687412.

Cdk5-Dependent Regulation of Rho Activity, Cytoskeletal Contraction, and Epithelial Cell Migration via Suppression of Src and p190RhoGAP

Brajendra K. Tripathi, Peggy S. Zelenka

Mol Cell Biol. 2009 Dec; 29(24): 6488–6499. Published online 2009 Oct 12. doi: 10.1128/MCB.01098-09

PMCID:: PMC2786874

Abstract Article PDF–4.8M

Select item 964785713.

N⁶‐methyladenosine‐modified lncRNA ARHGAP5‐AS1 stabilises CSDE1 and coordinates oncogenic RNA regulons in hepatocellular carcinoma

Jiandong Liu, Nasha Zhang, Jiajia Zeng, Teng Wang, Yue Shen, Chi Ma, Ming Yang

Clin Transl Med. 2022 Nov; 12(11): e1107. Published online 2022 Nov 10. doi: 10.1002/ctm2.1107

PMCID:: PMC9647857

Abstract Article PDF–6.8M

Select item 41357214.

The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion.

J McGlade, B Brunkhorst, D Anderson, G Mbamalu, J Settleman, S Dedhar, M Rozakis-Adcock, L B Chen, T Pawson

EMBO J. 1993 Aug; 12(8): 3073–3081. doi: 10.1002/j.1460-2075.1993.tb05976.x

PMCID:: PMC413572

Summary Page Browse PDF–2.7M

Select item 691869515.

Rnd Proteins Function as RhoA Antagonists by Activating p190 RhoGAP

Krister Wennerberg, Marie-Annick Forget, Shawn M. Ellerbroek, William T. Arthur, Keith Burridge, Jeffrey Settleman, Channing J. Der, Steen H. Hansen

Curr Biol. Author manuscript; available in PMC 2019 Dec 18.

Published in final edited form as: Curr Biol. 2003 Jul 1; 13(13): 1106–1115. doi: 10.1016/s0960-9822(03)00418-4

PMCID:: PMC6918695

Abstract Article PDF–1.8M

Select item 543061616.

Genome-Wide Analysis in Brazilians Reveals Highly Differentiated Native American Genome Regions

Josyf C. Mychaleckyj, Alexandre Havt, Uma Nayak, Relana Pinkerton, Emily Farber, Patrick Concannon, Aldo A. Lima, Richard L. Guerrant

Mol Biol Evol. 2017 Mar; 34(3): 559–574. Published online 2017 Jan 18. doi: 10.1093/molbev/msw249

PMCID:: PMC5430616

Abstract Article PDF–1.6M

Select item 369045417.

14-3-3 Proteins Interact with a Hybrid Prenyl-Phosphorylation Motif to Inhibit G Proteins

Philippe Riou, Svend Kjær, Ritu Garg, Andrew Purkiss, Roger George, Robert J. Cain, Ganka Bineva, Nicolas Reymond, Brad McColl, Andrew J. Thompson, Nicola O’Reilly, Neil Q. McDonald, Peter J. Parker, Anne J. Ridley

Cell. 2013 Apr 25; 153(3): 640–653. doi: 10.1016/j.cell.2013.03.044

Correction in:: Cell. 2013 May 23; 153(5): 1164.

PMCID:: PMC3690454

Abstract Article

Select item 966966818.

The complex of Fas-associated factor 1 with Hsp70 stabilizes the adherens junction integrity by suppressing RhoA activation

Soonhwa Song, Joon Kyu Park, Sang Chul Shin, Jae-Jin Lee, Seung Kon Hong, In-Kang Song, Bokyung Kim, Eun Joo Song, Kong-Joo Lee, Eunice EunKyeong Kim

J Mol Cell Biol. 2022 Jun; 14(6): mjac037. Published online 2022 Jun 15. doi: 10.1093/jmcb/mjac037

PMCID:: PMC9669668

Abstract Article PDF–3.1M

Select item 1011228119.

TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1

François Le Guerroué, Eric N Bunker, William M Rosencrans, Jack T Nguyen, Mohammed A Basar, Achim Werner, Tsui-Fen Chou, Chunxin Wang, Richard J Youle

Mol Cell. Author manuscript; available in PMC 2024 Mar 16.

Published in final edited form as: Mol Cell. 2023 Mar 16; 83(6): 927–941.e8. Published online 2023 Mar 9. doi: 10.1016/j.molcel.2023.02.023

PMCID:: PMC10112281

Abstract Article PDF–2.4M

Select item 439027220.

Nicole St-Denis, Gagan D. Gupta, Zhen Yuan Lin, Beatriz Gonzalez-Badillo, Laurence Pelletier, Anne-Claude Gingras

Mol Cell Proteomics. 2015 Apr; 14(4): 946–960. Published online 2015 Feb 6. doi: 10.1074/mcp.M114.046086

PMCID:: PMC4390272

Abstract Article PDF–814K

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