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Select item 82483211.

Differentiation and activation of human CD4 T cells is associated with a gradual loss of myelin and lymphocyte protein

Judith Leitner, Kodchakorn Mahasongkram, Philipp Schatzlmaier, Karin Pfisterer, Vladimir Leksa, Supansa Pata, Watchara Kasinrerk, Hannes Stockinger, Peter Steinberger

Eur J Immunol. 2021 Apr; 51(4): 848–863. Published online 2021 Jan 25. doi: 10.1002/eji.202048603

PMCID:: PMC8248321

Abstract Article PDF–3.6M

Select item 73392222.

Clostridium perfringens epsilon toxin binds to erythrocyte MAL receptors and triggers phosphatidylserine exposure

Zhijun Geng, Jing Huang, Lin Kang, Shan Gao, Yuan Yuan, Yanwei Li, Jing Wang, Wenwen Xin, Jinglin Wang

J Cell Mol Med. 2020 Jul; 24(13): 7341–7352. Published online 2020 May 28. doi: 10.1111/jcmm.15315

PMCID:: PMC7339222

Abstract Article PDF–1.8M

Select item 61468343.

The Cytotoxicity of Epsilon Toxin from Clostridium perfringens on Lymphocytes Is Mediated by MAL Protein Expression

Marta Blanch, Jonatan Dorca-Arévalo, Anna Not, Mercè Cases, Inmaculada Gómez de Aranda, Antonio Martínez-Yélamos, Sergio Martínez-Yélamos, Carles Solsona, Juan Blasi

Mol Cell Biol. 2018 Oct 1; 38(19): e00086-18. Prepublished online 2018 Jul 9. Published online 2018 Sep 14. doi: 10.1128/MCB.00086-18

PMCID:: PMC6146834

Abstract Article PDF–2.9M

Select item 54454974.

MAL gene overexpression as a marker of high-grade serous ovarian carcinoma stem-like cells that predicts chemoresistance and poor prognosis

Laura Zanotti, Chiara Romani, Laura Tassone, Paola Todeschini, Renata Alessandra Tassi, Elisabetta Bandiera, Giovanna Damia, Francesca Ricci, Laura Ardighieri, Stefano Calza, Sergio Marchini, Luca Beltrame, Germana Tognon, Maurizio D’Incalci, Sergio Pecorelli, Enrico Sartori, Franco Odicino, Antonella Ravaggi, Eliana Bignotti

BMC Cancer. 2017; 17: 366. Published online 2017 May 25. doi: 10.1186/s12885-017-3334-1

PMCID:: PMC5445497

Abstract Article PDF–884K

Select item 37891535.

MAL hypermethylation is a tissue-specific event that correlates with MAL mRNA expression in esophageal carcinoma

Zhe Jin, Liang Wang, Yuan Zhang, Yulan Cheng, Yan Gao, Xianling Feng, Ming Dong, Ziyi Cao, Si Chen, Huimin Yu, Zhenfu Zhao, Xiaojing Zhang, Jie Liu, Yuriko Mori, Xinmin Fan, Stephen J. Meltzer

Sci Rep. 2013; 3: 2838. Published online 2013 Oct 3. doi: 10.1038/srep02838

PMCID:: PMC3789153

Abstract Article PDF–610K

Select item 30029266.

Epigenetic silencing of MAL, a putative tumor suppressor gene, can contribute to human epithelium cell carcinoma

Wei Cao, Zhi-yuan Zhang, Qin Xu, Qiang Sun, Ming Yan, Jun Zhang, Ping Zhang, Ze-guang Han, Wan-tao Chen

Mol Cancer. 2010; 9: 296. Published online 2010 Nov 22. doi: 10.1186/1476-4598-9-296

PMCID:: PMC3002926

Abstract Article PDF–785K

Select item 27003467.

Inactivation of the MAL gene in breast cancer is a common event that predicts benefit from adjuvant chemotherapy

Hisani N. Horne, Paula S. Lee, Susan K. Murphy, Miguel A. Alonso, John A. Olson, Jr., Jeffrey R. Marks

Mol Cancer Res. Author manuscript; available in PMC 2010 Feb 1.

Published in final edited form as: Mol Cancer Res. 2009 Feb; 7(2): 199–209. Published online 2009 Feb 10. doi: 10.1158/1541-7786.MCR-08-0314

PMCID:: PMC2700346

Abstract Article PDF–1.4M

Select item 26006878.

MAL promoter hypermethylation as a novel prognostic marker in gastric cancer

T E Buffart, R M Overmeer, R D M Steenbergen, M Tijssen, N C T van Grieken, P J F Snijders, H I Grabsch, C J H van de Velde, B Carvalho, G A Meijer

Br J Cancer. 2008 Dec 2; 99(11): 1802–1807. Published online 2008 Nov 11. doi: 10.1038/sj.bjc.6604777

PMCID:: PMC2600687

Abstract Article PDF–152K

Select item 22926859.

Hypermethylated MAL gene – a silent marker of early colon tumorigenesis

Guro E Lind, Terje Ahlquist, Matthias Kolberg, Marianne Berg, Mette Eknæs, Miguel A Alonso, Anne Kallioniemi, Gunn I Meling, Rolf I Skotheim, Torleiv O Rognum, Espen Thiis-Evensen, Ragnhild A Lothe

J Transl Med. 2008; 6: 13. Published online 2008 Mar 17. doi: 10.1186/1479-5876-6-13

PMCID:: PMC2292685

Abstract Article PDF–1.4M

Select item 121806110.

The MAL proteolipid is a component of the detergent-insoluble membrane subdomains of human T-lymphocytes.

J Millán, R Puertollano, L Fan, C Rancaño, M A Alonso

Biochem J. 1997 Jan 1; 321(Pt 1): 247–252. doi: 10.1042/bj3210247

PMCID:: PMC1218061

Summary PDF–372K

Select item 30457011.

cDNA cloning and sequence of MAL, a hydrophobic protein associated with human T-cell differentiation.

M A Alonso, S M Weissman

Proc Natl Acad Sci U S A. 1987 Apr; 84(7): 1997–2001. doi: 10.1073/pnas.84.7.1997

PMCID:: PMC304570

Summary Page Browse PDF–1.1M

Select item 2561312.

MAL, an Integral Element of the Apical Sorting Machinery, Is an Itinerant Protein That Cycles between the Trans-Golgi Network and the Plasma Membrane

Rosa Puertollano, Miguel A. Alonso

Mol Biol Cell. 1999 Oct; 10(10): 3435–3447. doi: 10.1091/mbc.10.10.3435

PMCID:: PMC25613

Abstract Article PDF–670K

Select item 880030813.

MAL protein suppresses the metastasis and invasion of GC cells by interfering with the phosphorylation of STAT3

Zhijun Geng, Jing Li, Sandang Li, Yueyue Wang, Lele Zhang, Qiuzi Hu, Xinru Wang, Lugen Zuo, Xue Song, Xiaofeng Zhang, Sitang Ge, Jianguo Hu

J Transl Med. 2022; 20: 50. Published online 2022 Jan 29. doi: 10.1186/s12967-022-03254-5

PMCID:: PMC8800308

Abstract Article PDF–3.4M

Select item 1092496714.

MAL expression downregulation through suppressive H3K27me3 marks at the promoter in HPV16-related cervical cancers is prognostically relevant and manifested by the interplay of novel MAL antisense long noncoding RNA AC103563.8, E7 oncoprotein and EZH2

Abarna Sinha, Abhisikta Ghosh, Arnab Ghosh, Sonia Mathai, Jaydip Bhaumik, Asima Mukhopadhyay, Arindam Maitra, Nidhan K. Biswas, Sharmila Sengupta

Clin Epigenetics. 2024; 16: 40. Published online 2024 Mar 10. doi: 10.1186/s13148-024-01651-9

PMCID:: PMC10924967

Abstract Article PDF–3.7M

Select item 457225515.

Differential gene expression between squamous cell carcinoma of esophageus and its normal epithelium; altered pattern of mal, akr1c2, and rab11a expression

Sakineh Kazemi-Noureini, Sergio Colonna-Romano, Abed-Ali Ziaee, Mohammad-Ali Malboobi, Mansour Yazdanbod, Parviz Setayeshgar, Bruno Maresca

World J Gastroenterol. 2004 Jun 15; 10(12): 1716–1721. Published online 2004 Jun 15. doi: 10.3748/wjg.v10.i12.1716

PMCID:: PMC4572255

Abstract Article PDF–183K

Select item 443912616.

The Myelin and Lymphocyte Protein MAL Is Required for Binding and Activity of Clostridium perfringens ε-Toxin

Kareem Rashid Rumah, Yinghua Ma, Jennifer R. Linden, Myat Lin Oo, Josef Anrather, Nicole Schaeren-Wiemers, Miguel A. Alonso, Vincent A. Fischetti, Mark S. McClain, Timothy Vartanian

PLoS Pathog. 2015 May; 11(5): e1004896. Published online 2015 May 20. doi: 10.1371/journal.ppat.1004896

PMCID:: PMC4439126

Abstract Article PDF–14M

Select item 362165217.

Aberrant methylation of LINE-1, SLIT2, MAL and IGFBP7 in non-small cell lung cancer

MAKOTO SUZUKI, KENJI SHIRAISHI, AYAMI EGUCHI, KOEI IKEDA, TAKESHI MORI, KENTARO YOSHIMOTO, YASUOMI OHBA, TATSUYA YAMADA, TAKAAKI ITO, YOSHIFUMI BABA, HIDEO BABA

Oncol Rep. 2013 Apr; 29(4): 1308–1314. Published online 2013 Jan 31. doi: 10.3892/or.2013.2266

PMCID:: PMC3621652

Abstract Article PDF–519K

Select item 351776918.

Development of a multiplex methylation-specific PCR as candidate triage test for women with an HPV-positive cervical scrape

Suzanne Snellenberg, Lise MA De Strooper, Albertus T Hesselink, Chris JLM Meijer, Peter JF Snijders, Daniëlle AM Heideman, Renske DM Steenbergen

BMC Cancer. 2012; 12: 551. Published online 2012 Nov 23. doi: 10.1186/1471-2407-12-551

PMCID:: PMC3517769

Abstract Article PDF–2.2M

Select item 461240919.

DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancer

Alexandra Kalmár, Bálint Péterfia, Péter Hollósi, Orsolya Galamb, Sándor Spisák, Barnabás Wichmann, András Bodor, Kinga Tóth, Árpád V. Patai, Gábor Valcz, Zsófia Brigitta Nagy, Vivien Kubák, Zsolt Tulassay, Ilona Kovalszky, Béla Molnár

BMC Cancer. 2015; 15: 736. Published online 2015 Oct 19. doi: 10.1186/s12885-015-1687-x

PMCID:: PMC4612409

Abstract Article PDF–1.5M

Select item 357187120.

MYADM controls endothelial barrier function through ERM-dependent regulation of ICAM-1 expression

Juan F. Aranda, Natalia Reglero-Real, Beatriz Marcos-Ramiro, Ana Ruiz-Sáenz, Laura Fernández-Martín, Miguel Bernabé-Rubio, Leonor Kremer, Anne J. Ridley, Isabel Correas, Miguel A. Alonso, Jaime Millán

Mol Biol Cell. 2013 Feb 15; 24(4): 483–494. doi: 10.1091/mbc.E11-11-0914