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Select item 111677981.

Cryo-EM structures reveal tau filaments from Down syndrome adopt Alzheimer’s disease fold

Ujjayini Ghosh, Eric Tse, Hyunjun Yang, Marie Shi, Christoffer D. Caro, Feng Wang, Gregory E. Merz, Stanley B. Prusiner, Daniel R. Southworth, Carlo Condello

Acta Neuropathol Commun. 2024; 12: 94. Published online 2024 Jun 12. doi: 10.1186/s40478-024-01806-y

PMCID:: PMC11167798

Abstract Article PDF–2.9M

Select item 111460732.

Microtubule associated protein tau binds to double-stranded but not single-stranded DNA

Q. Hua, R.-Q. He, N. Haque, M.-H. Qu, A. del Carmen Alonso, I. Grundke-Iqbal, K. Iqbal

Cell Mol Life Sci. 2003 Feb; 60(2): 413–421. doi: 10.1007/s000180300034

PMCID:: PMC11146073

Abstract Article PDF–358K

Select item 111158923.

d-Ribosylated Tau forms globular aggregates with high cytotoxicity

Lan Chen, Yan Wei, Xueqing Wang, Rongqiao He

Cell Mol Life Sci. 2009 Aug; 66(15): 2559–2571. Published online 2009 Jun 11. doi: 10.1007/s00018-009-0058-7

PMCID:: PMC11115892

Abstract Article PDF–686K

Select item 111138084.

Transport and diffusion of Tau protein in neurons

Tim Scholz, Eckhard Mandelkow

Cell Mol Life Sci. 2014 Aug; 71(16): 3139–3150. Published online 2014 Apr 1. doi: 10.1007/s00018-014-1610-7

PMCID:: PMC11113808

Abstract Article PDF–988K

Select item 111085335.

Behind the curtain of tauopathy: a show of multiple players orchestrating tau toxicity

Yunpeng Huang, Zhihao Wu, Bing Zhou

Cell Mol Life Sci. 2016 Jan; 73(1): 1–21. Published online 2015 Sep 24. doi: 10.1007/s00018-015-2042-8

PMCID:: PMC11108533

Abstract Article PDF–1.0M

Select item 110932466.

Cognitive phenotype and neurodegeneration associated with Tau in Huntington's disease

Saul Martinez‐Horta, Jesús Perez‐Perez, Rocío Perez‐Gonzalez, Frederic Sampedro, Andrea Horta‐Barba, Antonia Campolongo, Elisa Rivas‐Asensio, Arnau Puig‐Davi, Javier Pagonabarraga, Jaime Kulisevsky

Ann Clin Transl Neurol. 2024 May; 11(5): 1160–1171. Published online 2024 Mar 27. doi: 10.1002/acn3.52031

PMCID:: PMC11093246

Abstract Article PDF–1.4M

Select item 110734377.

The structure and phase of tau: from monomer to amyloid filament

Yifan Zeng, Jing Yang, Bailing Zhang, Meng Gao, Zhengding Su, Yongqi Huang

Cell Mol Life Sci. 2021 Mar; 78(5): 1873–1886. Published online 2020 Oct 19. doi: 10.1007/s00018-020-03681-x

PMCID:: PMC11073437

Abstract Article PDF–992K

Select item 110728758.

Differential effects of putative N-glycosylation sites in human Tau on Alzheimer’s disease-related neurodegeneration

Yelena Losev, Moran Frenkel-Pinter, Malak Abu-Hussien, Guru Krishnakumar Viswanathan, Donna Elyashiv-Revivo, Rana Geries, Isam Khalaila, Ehud Gazit, Daniel Segal

Cell Mol Life Sci. 2021 Mar; 78(5): 2231–2245. Published online 2020 Sep 14. doi: 10.1007/s00018-020-03643-3

PMCID:: PMC11072875

Abstract Article PDF–3.2M

Select item 110325789.

Speech patterns during memory recall relates to early tau burden across adulthood

Christina B. Young, Viktorija Smith, Cody Karjadi, Selah‐Marie Grogan, Ting Fang Alvin Ang, Philip S. Insel, Victor W. Henderson, Meghan Sumner, Kathleen L. Poston, Rhoda Au, Elizabeth C. Mormino

Alzheimers Dement. 2024 Apr; 20(4): 2552–2563. Published online 2024 Feb 13. doi: 10.1002/alz.13731

PMCID:: PMC11032578

Abstract Article PDF–19M

Select item 1103252710.

Tau accumulation and atrophy predict amyloid independent cognitive decline in aging

Corrina S. Fonseca, Suzanne L. Baker, Lindsey Dobyns, Mustafa Janabi, William J. Jagust, Theresa M. Harrison

Alzheimers Dement. 2024 Apr; 20(4): 2526–2537. Published online 2024 Feb 9. doi: 10.1002/alz.13654

PMCID:: PMC11032527

Abstract Article PDF–3.2M

Select item 1095335311.

Identification of phosphorylated tau protein interactors in progressive supranuclear palsy (PSP) reveals networks involved in protein degradation, stress response, cytoskeletal dynamics, metabolic processes, and neurotransmission

Rowan A. W. Radford, Stephanie L. Rayner, Paulina Szwaja, Marco Morsch, Flora Cheng, Tianyi Zhu, Jocelyn Widagdo, Victor Anggono, Dean L. Pountney, Roger Chung, Albert Lee

J Neurochem. 2023 May; 165(4): 563–586. Published online 2023 Mar 21. doi: 10.1111/jnc.15796

PMCID:: PMC10953353

Abstract Article PDF–12M

Select item 1094309212.

Complexes of tubulin oligomers and tau form a viscoelastic intervening network cross-bridging microtubules into bundles

Phillip A. Kohl, Chaeyeon Song, Bretton J. Fletcher, Rebecca L. Best, Christine Tchounwou, Ximena Garcia Arceo, Peter J. Chung, Herbert P. Miller, Leslie Wilson, Myung Chul Choi, Youli Li, Stuart C. Feinstein, Cyrus R. Safinya

Nat Commun. 2024; 15: 2362. Published online 2024 Mar 15. doi: 10.1038/s41467-024-46438-x

PMCID:: PMC10943092

Abstract Article PDF–6.0M

Select item 1092139513.

Behavioral and Neurophysiological Implications of Pathological Human Tau Expression in Serotonin Neurons

Nazmus S. Khan, Juan Uribe Isaza, Nahid Rouhi, Naila F. Jamani, Shaista Jabeen, Amisha K. Gill, Mio Tsutsui, Frank Visser, Derya Sargin

ACS Chem Neurosci. 2024 Mar 6; 15(5): 932–943. Published online 2024 Feb 20. doi: 10.1021/acschemneuro.3c00626

PMCID:: PMC10921395

Abstract Article PDF–4.5M

Select item 1084902214.

Affection of Motor Network Regions by Tau Pathology Across the Alzheimer's Disease Spectrum

Gérard N. Bischof, Elena Jaeger, Kathrin Giehl, Merle C. Hönig, for the Alzheimer’s Disease Neuroimaging Initiative, Peter H. Weiss, Alexander Drzezga

eNeuro. 2024 Jan; 11(1): ENEURO.0242-23.2023. Prepublished online 2023 Dec 8. Published online 2024 Jan 16. doi: 10.1523/ENEURO.0242-23.2023

PMCID:: PMC10849022

Abstract Article PDF–487K

Select item 1084367715.

Plasma phosphorylated tau‐217 exhibits sex‐specific prognostication of cognitive decline and brain atrophy in cognitively unimpaired adults

Rowan Saloner, Lawren VandeVrede, Breton M. Asken, Emily W. Paolillo, Eva Q. Gontrum, Amy Wolf, Argentina Lario‐Lago, Marta Milà‐Alomà, Gallen Triana‐Baltzer, Hartmuth C. Kolb, Dena B. Dubal, Gil D. Rabinovici, Bruce L. Miller, Adam L. Boxer, Kaitlin B. Casaletto, Joel H. Kramer

Alzheimers Dement. 2024 Jan; 20(1): 376–387. Published online 2023 Aug 28. doi: 10.1002/alz.13454

PMCID:: PMC10843677

Abstract Article PDF–1.3M

Select item 1083833116.

Local structural preferences in shaping tau amyloid polymorphism

Nikolaos Louros, Martin Wilkinson, Grigoria Tsaka, Meine Ramakers, Chiara Morelli, Teresa Garcia, Rodrigo Gallardo, Sam D’Haeyer, Vera Goossens, Dominique Audenaert, Dietmar Rudolf Thal, Ian R. Mackenzie, Rosa Rademakers, Neil A. Ranson, Sheena E. Radford, Frederic Rousseau, Joost Schymkowitz

Nat Commun. 2024; 15: 1028. Published online 2024 Feb 3. doi: 10.1038/s41467-024-45429-2

PMCID:: PMC10838331

Abstract Article PDF–4.9M

Select item 1083425717.

Glial reactivity and T cell infiltration in frontotemporal lobar degeneration with tau pathology

Iain J Hartnell, Declan Woodhouse, William Jasper, Luke Mason, Pavan Marwaha, Manon Graffeuil, Laurie C Lau, Jeanette L Norman, David S Chatelet, Luc Buee, James A R Nicoll, David Blum, Guillaume Dorothee, Delphine Boche

Brain. 2024 Feb; 147(2): 590–606. Published online 2023 Sep 13. doi: 10.1093/brain/awad309

PMCID:: PMC10834257

Abstract Article PDF–2.2M

Select item 1081568718.

MAPT Locus in Parkinson’s Disease Patients of Ashkenazi Origin: A Stratified Analysis

Shachar Shani, Mali Gana-Weisz, Anat Bar-Shira, Avner Thaler, Tanya Gurevich, Anat Mirelman, Nir Giladi, Roy N. Alcalay, Orly Goldstein, Avi Orr-Urtreger

Genes (Basel) 2024 Jan; 15(1): 46. Published online 2023 Dec 28. doi: 10.3390/genes15010046

PMCID:: PMC10815687

Abstract Article PDF–1.0M

Select item 1078959519.

Intron retention as a productive mechanism in human MAPT: RNA species generated by retention of intron 3

Daniel Ruiz-Gabarre, Laura Vallés-Saiz, Almudena Carnero-Espejo, Isidro Ferrer, Félix Hernández, Ramon Garcia-Escudero, Jesús Ávila, Vega García-Escudero

eBioMedicine. 2024 Feb; 100: 104953. Published online 2024 Jan 5. doi: 10.1016/j.ebiom.2023.104953

PMCID:: PMC10789595

Abstract Article PDF–2.9M

Select item 1074337520.

Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold

Chao Qi, Bert M. Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G. Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, Eleonora Aronica, Yoshifumi Hirokawa, Kiyomitsu Oyanagi, Akiyoshi Kakita, Benjamin Ryskeldi-Falcon, Mari Yoshida, Masato Hasegawa, Sjors H. W. Scheres, Michel Goedert

Proc Natl Acad Sci U S A. 2023 Dec 19; 120(51): e2306767120. Published online 2023 Dec 15. doi: 10.1073/pnas.2306767120

PMCID:: PMC10743375

Abstract Article PDF–1.9M

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PMC Links for Gene (Select 4137) (1140)
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LOC101928728 [Homo sapiens]
LOC101928728 [Homo sapiens]
Gene ID:101928728

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Gene Links for GEO Profiles (Select 132666189) (1)
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Acute alcohol consumption effect on whole blood (control group): time course
Acute alcohol consumption effect on whole blood (control group): time course
Accession: GDS6177

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Related DataSets for GEO Profiles (Select 132672984) (1)
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