PMC Links for Gene (Select 4168) - PMC

Select item 46144821.

Dbl oncogene expression in MCF-10 A epithelial cells disrupts mammary acinar architecture, induces EMT and angiogenic factor secretion

Cristina Vanni, Marzia Ognibene, Federica Finetti, Patrizia Mancini, Sara Cabodi, Daniela Segalerba, Maria Rosaria Torrisi, Sandra Donnini, Maria Carla Bosco, Luigi Varesio, Alessandra Eva

Cell Cycle. 2015 May 1; 14(9): 1426–1437. Published online 2015 Feb 27. doi: 10.1080/15384101.2015.1021516

PMCID:: PMC4614482

Abstract Article PDF–1000K

Select item 4571162.

Molecular cloning and characterization of the human dbl proto-oncogene: evidence that its overexpression is sufficient to transform NIH/3T3 cells.

D Ron, S R Tronick, S A Aaronson, A Eva

EMBO J. 1988 Aug; 7(8): 2465–2473. doi: 10.1002/j.1460-2075.1988.tb03093.x

PMCID:: PMC457116

Summary Page Browse PDF–1.7M

Select item 3870343.

Identification of the protein encoded by the human diffuse B-cell lymphoma (dbl) oncogene.

S K Srivastava, R H Wheelock, S A Aaronson, A Eva

Proc Natl Acad Sci U S A. 1986 Dec; 83(23): 8868–8872. doi: 10.1073/pnas.83.23.8868

PMCID:: PMC387034

Summary Page Browse PDF–1.6M

Select item 2799284.

The predicted DBL oncogene product defines a distinct class of transforming proteins.

A Eva, G Vecchio, C D Rao, S R Tronick, S A Aaronson

Proc Natl Acad Sci U S A. 1988 Apr; 85(7): 2061–2065. doi: 10.1073/pnas.85.7.2061

PMCID:: PMC279928

Summary Page Browse PDF–1.0M

Select item 865895.

Oligomerization of DH Domain Is Essential for Dbl-Induced Transformation

Kejin Zhu, Balazs Debreceni, Feng Bi, Yi Zheng

Mol Cell Biol. 2001 Jan; 21(2): 425–437. doi: 10.1128/MCB.21.2.425-437.2001

PMCID:: PMC86589

Abstract Article PDF–2.8M

Select item 67748586.

Src-dependent DBL family members drive resistance to vemurafenib in human melanoma

Charlotte R. Feddersen, Jacob L. Schillo, Afshin Varzavand, Hayley R. Vaughn, Lexy S. Wadsworth, Andrew P. Voigt, Eliot Y. Zhu, Brooke M. Jennings, Sarah A. Mullen, Jeremy Bobera, Jesse D. Riordan, Christopher S. Stipp, Adam J. Dupuy

Cancer Res. Author manuscript; available in PMC 2020 Apr 1.

Published in final edited form as: Cancer Res. 2019 Oct 1; 79(19): 5074–5087. Published online 2019 Aug 15. doi: 10.1158/0008-5472.CAN-19-0244

PMCID:: PMC6774858

Abstract Article PDF–1.9M

Select item 19493667.

Activated Ezrin Promotes Cell Migration through Recruitment of the GEF Dbl to Lipid Rafts and Preferential Downstream Activation of Cdc42

Soren Prag, Maddy Parsons, Melanie D. Keppler, Simon M. Ameer-Beg, Paul Barber, James Hunt, Andrew J. Beavil, Rosy Calvert, Monique Arpin, Borivoj Vojnovic, Tony Ng

Mol Biol Cell. 2007 Aug; 18(8): 2935–2948. doi: 10.1091/mbc.E06-11-1031

PMCID:: PMC1949366

Abstract Article PDF–2.5M

Select item 26551138.

Gα_q Directly Activates p63RhoGEF and Trio via a Conserved Extension of the Dbl Homology-associated Pleckstrin Homology Domain

Rafael J. Rojas, Marielle E. Yohe, Svetlana Gershburg, Takeharu Kawano, Tohru Kozasa, John Sondek

J Biol Chem. Author manuscript; available in PMC 2009 Mar 13.

Published in final edited form as: J Biol Chem. 2007 Oct 5; 282(40): 29201–29210. Published online 2007 Jul 2. doi: 10.1074/jbc.M703458200

PMCID:: PMC2655113

Abstract Article PDF–965K

Select item 18204569.

Regulation of Proto-Oncogenic Dbl by Chaperone-Controlled, Ubiquitin-Mediated Degradation

Elena Kamynina, Krista Kauppinen, Faping Duan, Nora Muakkassa, Danny Manor

Mol Cell Biol. 2007 Mar; 27(5): 1809–1822. Published online 2006 Dec 18. doi: 10.1128/MCB.01051-06

PMCID:: PMC1820456

Abstract Article PDF–1.4M

Select item 344035610.

Phosphoinositide 3-Kinase C2β Regulates RhoA and the Actin Cytoskeleton through an Interaction with Dbl

Karolina Błajecka, Marin Marinov, Laura Leitner, Kristin Uth, Guido Posern, Alexandre Arcaro

PLoS One. 2012; 7(9): e44945. Published online 2012 Sep 12. doi: 10.1371/journal.pone.0044945

PMCID:: PMC3440356

Abstract Article PDF–971K

Select item 319103811.

The Tumor Suppressor Hamartin Enhances Dbl Protein Transforming Activity through Interaction with Ezrin

Marzia Ognibene, Cristina Vanni, Daniela Segalerba, Patrizia Mancini, Elisa Merello, Maria Rosaria Torrisi, Maria Carla Bosco, Luigi Varesio, Alessandra Eva

J Biol Chem. 2011 Aug 26; 286(34): 29973–29983. Published online 2011 Jun 28. doi: 10.1074/jbc.M111.270785

PMCID:: PMC3191038

Abstract Article PDF–2.3M

Select item 328913912.

Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia

A Piton, J Gauthier, FF Hamdan, RG Lafrenière, Y Yang, E Henrion, S Laurent, A Noreau, P Thibodeau, L Karemera, D Spiegelman, F Kuku, J Duguay, L Destroismaisons, P Jolivet, M Côté, K Lachapelle, O Diallo, A Raymond, C Marineau, N Champagne, L Xiong, C Gaspar, J-B Rivière, J Tarabeux, P Cossette, M-O Krebs, JL Rapoport, A Addington, LE DeLisi, L Mottron, R Joober, E Fombonne, P Drapeau, GA Rouleau

Mol Psychiatry. Author manuscript; available in PMC 2012 Feb 28.

Published in final edited form as: Mol Psychiatry. 2011 Aug; 16(8): 867–880. Published online 2010 May 18. doi: 10.1038/mp.2010.54

PMCID:: PMC3289139

Abstract Article PDF–1.2M

Select item 675758313.

Activation of Rac GTPase by p75 Is Necessary for c-jun N-Terminal Kinase-Mediated Apoptosis

Anthony W. Harrington, Ju Young Kim, Sung Ok Yoon

J Neurosci. 2002 Jan 1; 22(1): 156–166. doi: 10.1523/JNEUROSCI.22-01-00156.2002

PMCID:: PMC6757583

Abstract Article PDF–582K

Select item 266528614.

The DNA sequence of the human X chromosome

Mark T. Ross, Darren V. Grafham, Alison J. Coffey, Steven Scherer, Kirsten McLay, Donna Muzny, Matthias Platzer, Gareth R. Howell, Christine Burrows, Christine P. Bird, Adam Frankish, Frances L. Lovell, Kevin L. Howe, Jennifer L. Ashurst, Robert S. Fulton, Ralf Sudbrak, Gaiping Wen, Matthew C. Jones, Matthew E. Hurles, T. Daniel Andrews, Carol E. Scott, Stephen Searle, Juliane Ramser, Adam Whittaker, Rebecca Deadman, Nigel P. Carter, Sarah E. Hunt, Rui Chen, Andrew Cree, Preethi Gunaratne, Paul Havlak, Anne Hodgson, Michael L. Metzker, Stephen Richards, Graham Scott, David Steffen, Erica Sodergren, David A. Wheeler, Kim C. Worley, Rachael Ainscough, Kerrie D. Ambrose, M. Ali Ansari-Lari, Swaroop Aradhya, Robert I. S. Ashwell, Anne K. Babbage, Claire L. Bagguley, Andrea Ballabio, Ruby Banerjee, Gary E. Barker, Karen F. Barlow, Ian P. Barrett, Karen N. Bates, David M. Beare, Helen Beasley, Oliver Beasley, Alfred Beck, Graeme Bethel, Karin Blechschmidt, Nicola Brady, Sarah Bray-Allen, Anne M. Bridgeman, Andrew J. Brown, Mary J. Brown, David Bonnin, Elspeth A. Bruford, Christian Buhay, Paula Burch, Deborah Burford, Joanne Burgess, Wayne Burrill, John Burton, Jackie M. Bye, Carol Carder, Laura Carrel, Joseph Chako, Joanne C. Chapman, Dean Chavez, Ellson Chen, Guan Chen, Yuan Chen, Zhijian Chen, Craig Chinault, Alfredo Ciccodicola, Sue Y. Clark, Graham Clarke, Chris M. Clee, Sheila Clegg, Kerstin Clerc-Blankenburg, Karen Clifford, Vicky Cobley, Charlotte G. Cole, Jen S. Conquer, Nicole Corby, Richard E. Connor, Robert David, Joy Davies, Clay Davis, John Davis, Oliver Delgado, Denise DeShazo, Pawandeep Dhami, Yan Ding, Huyen Dinh, Steve Dodsworth, Heather Draper, Shannon Dugan-Rocha, Andrew Dunham, Matthew Dunn, K. James Durbin, Ireena Dutta, Tamsin Eades, Matthew Ellwood, Alexandra Emery-Cohen, Helen Errington, Kathryn L. Evans, Louisa Faulkner, Fiona Francis, John Frankland, Audrey E. Fraser, Petra Galgoczy, James Gilbert, Rachel Gill, Gernot Glöckner, Simon G. Gregory, Susan Gribble, Coline Griffiths, Russell Grocock, Yanghong Gu, Rhian Gwilliam, Cerissa Hamilton, Elizabeth A. Hart, Alicia Hawes, Paul D. Heath, Katja Heitmann, Steffen Hennig, Judith Hernandez, Bernd Hinzmann, Sarah Ho, Michael Hoffs, Phillip J. Howden, Elizabeth J. Huckle, Jennifer Hume, Paul J. Hunt, Adrienne R. Hunt, Judith Isherwood, Leni Jacob, David Johnson, Sally Jones, Pieter J. de Jong, Shirin S. Joseph, Stephen Keenan, Susan Kelly, Joanne K. Kershaw, Ziad Khan, Petra Kioschis, Sven Klages, Andrew J. Knights, Anna Kosiura, Christie Kovar-Smith, Gavin K. Laird, Cordelia Langford, Stephanie Lawlor, Margaret Leversha, Lora Lewis, Wen Liu, Christine Lloyd, David M. Lloyd, Hermela Loulseged, Jane E. Loveland, Jamieson D. Lovell, Ryan Lozado, Jing Lu, Rachael Lyne, Jie Ma, Manjula Maheshwari, Lucy H. Matthews, Jennifer McDowall, Stuart McLaren, Amanda McMurray, Patrick Meidl, Thomas Meitinger, Sarah Milne, George Miner, Shailesh L. Mistry, Margaret Morgan, Sidney Morris, Ines Müller, James C. Mullikin, Ngoc Nguyen, Gabriele Nordsiek, Gerald Nyakatura, Christopher N. O’Dell, Geoffery Okwuonu, Sophie Palmer, Richard Pandian, David Parker, Julia Parrish, Shiran Pasternak, Dina Patel, Alex V. Pearce, Danita M. Pearson, Sarah E. Pelan, Lesette Perez, Keith M. Porter, Yvonne Ramsey, Kathrin Reichwald, Susan Rhodes, Kerry A. Ridler, David Schlessinger, Mary G. Schueler, Harminder K. Sehra, Charles Shaw-Smith, Hua Shen, Elizabeth M. Sheridan, Ratna Shownkeen, Carl D. Skuce, Michelle L. Smith, Elizabeth C. Sotheran, Helen E. Steingruber, Charles A. Steward, Roy Storey, R. Mark Swann, David Swarbreck, Paul E. Tabor, Stefan Taudien, Tineace Taylor, Brian Teague, Karen Thomas, Andrea Thorpe, Kirsten Timms, Alan Tracey, Steve Trevanion, Anthony C. Tromans, Michele d’Urso, Daniel Verduzco, Donna Villasana, Lenee Waldron, Melanie Wall, Qiaoyan Wang, James Warren, Georgina L. Warry, Xuehong Wei, Anthony West, Siobhan L. Whitehead, Mathew N. Whiteley, Jane E. Wilkinson, David L. Willey, Gabrielle Williams, Leanne Williams, Angela Williamson, Helen Williamson, Laurens Wilming, Rebecca L. Woodmansey, Paul W. Wray, Jennifer Yen, Jingkun Zhang, Jianling Zhou, Huda Zoghbi, Sara Zorilla, David Buck, Richard Reinhardt, Annemarie Poustka, André Rosenthal, Hans Lehrach, Alfons Meindl, Patrick J. Minx, LaDeana W. Hillier, Huntington F. Willard, Richard K. Wilson, Robert H. Waterston, Catherine M. Rice, Mark Vaudin, Alan Coulson, David L. Nelson, George Weinstock, John E. Sulston, Richard Durbin, Tim Hubbard, Richard A. Gibbs, Stephan Beck, Jane Rogers, David R. Bentley

Nature. Author manuscript; available in PMC 2009 Apr 5.

Published in final edited form as: Nature. 2005 Mar 17; 434(7031): 325–337. doi: 10.1038/nature03440

PMCID:: PMC2665286

Abstract Article PDF–1.0M

Select item 135612915.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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