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Select item 111602221.

Preoperative serum midkine concentration is a prognostic marker for esophageal squamous cell carcinoma

Hideaki Shimada, Yoshihiro Nabeya, Masatoshi Tagawa, Shin‐ichi Okazumi, Hisahiro Matsubara, Kenji Kadomatsu, Takashi Muramatsu, Shinya Ikematsu, Sadatoshi Sakuma, Takenori Ochiai

Cancer Sci. 2003 Jul; 94(7): 628–632. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01494.x

PMCID:: PMC11160222

Abstract Article PDF–157K

Select item 111598022.

Plasma midkine level is a prognostic factor for human neuroblastoma

Shinya Ikematsu, Akira Nakagawara, Yohko Nakamura, Miki Ohira, Masaki Shinjo, Satoshi Kishida, Kenji Kadomatsu

Cancer Sci. 2008 Oct; 99(10): 2070–2074. Published online 2008 Oct 19. doi: 10.1111/j.1349-7006.2008.00957.x

PMCID:: PMC11159802

Abstract Article PDF–220K

Select item 111597363.

Midkine in plasma as a novel breast cancer marker

Mutsuko Ibusuki, Hiromi Fujimori, Yutaka Yamamoto, Kazutoshi Ota, Mitsuharu Ueda, Satoru Shinriki, Masahiro Taketomi, Sadatoshi Sakuma, Masanori Shinohara, Hirotaka Iwase, Yukio Ando

Cancer Sci. 2009 Sep; 100(9): 1735–1739. Published online 2009 Jun 1. doi: 10.1111/j.1349-7006.2009.01233.x

PMCID:: PMC11159736

Abstract Article PDF–348K

Select item 111594894.

Midkine and its clinical significance in endometrial carcinoma

Kojiro Tanabe, Mitsuyo Matsumoto, Shinya Ikematsu, Satoru Nagase, Atsushi Hatakeyama, Tadao Takano, Hitoshi Niikura, Kiyoshi Ito, Kenji Kadomatsu, Shin‐ichi Hayashi, Nobuo Yaegashi

Cancer Sci. 2008 Jun; 99(6): 1125–1130. Published online 2008 Apr 14. doi: 10.1111/j.1349-7006.2008.00796.x

PMCID:: PMC11159489

Abstract Article PDF–168K

Select item 111211715.

Spatial and single-cell colocalisation analysis reveals MDK-mediated immunosuppressive environment with regulatory T cells in colorectal carcinogenesis

Masahiro Hashimoto, Yasuhiro Kojima, Takeharu Sakamoto, Yuki Ozato, Yusuke Nakano, Tadashi Abe, Kiyotaka Hosoda, Hideyuki Saito, Satoshi Higuchi, Yuichi Hisamatsu, Takeo Toshima, Yusuke Yonemura, Takaaki Masuda, Tsuyoshi Hata, Satoshi Nagayama, Koichi Kagawa, Yasuhiro Goto, Mitsuaki Utou, Ayako Gamachi, Kiyomi Imamura, Yuta Kuze, Junko Zenkoh, Ayako Suzuki, Kazuki Takahashi, Atsushi Niida, Haruka Hirose, Shuto Hayashi, Jun Koseki, Satoshi Fukuchi, Kazunari Murakami, Tomoharu Yoshizumi, Kenji Kadomatsu, Taro Tobo, Yoshinao Oda, Mamoru Uemura, Hidetoshi Eguchi, Yuichiro Doki, Masaki Mori, Masanobu Oshima, Tatsuhiro Shibata, Yutaka Suzuki, Teppei Shimamura, Koshi Mimori

eBioMedicine. 2024 May; 103: 105102. Published online 2024 Apr 12. doi: 10.1016/j.ebiom.2024.105102

PMCID:: PMC11121171

Abstract Article PDF–6.4M

Select item 108143266.

Midkine (MDK) in Hepatocellular Carcinoma: More than a Biomarker

Christiana Christou, Andreas Stylianou, Vasiliki Gkretsi

Cells. 2024 Jan; 13(2): 136. Published online 2024 Jan 11. doi: 10.3390/cells13020136

PMCID:: PMC10814326

Abstract Article PDF–1.3M

Select item 107790747.

Elevated Midkine Serum Levels Are Associated with Long-Term Survival in Critically Ill Patients

Philipp Hohlstein, Samira Abu Jhaisha, Eray Yagmur, Dennis Wawer, Maike R. Pollmanns, Jule K. Adams, Theresa H. Wirtz, Jonathan F. Brozat, Lukas Bündgens, Karim Hamesch, Ralf Weiskirchen, Frank Tacke, Christian Trautwein, Alexander Koch

Int J Mol Sci. 2024 Jan; 25(1): 454. Published online 2023 Dec 29. doi: 10.3390/ijms25010454

PMCID:: PMC10779074

Abstract Article PDF–1.4M

Select item 94183238.

Midkine expression by stem-like tumor cells drives persistence to mTOR inhibition and an immune-suppressive microenvironment

Yan Tang, David J. Kwiatkowski, Elizabeth P. Henske

Nat Commun. 2022; 13: 5018. Published online 2022 Aug 26. doi: 10.1038/s41467-022-32673-7

PMCID:: PMC9418323

Abstract Article PDF–11M

Select item 85565499.

Serum midkine level might be a diagnostic tool for COVID19 disease in pregnancy: From the disease severity, hospitalization and disease progression respects

Nuray Yazihan, Seyit Ahmet Erol, Sevginur Akdas, Sule Goncu Ayhan, Aysegul Atalay, Muradiye Yildirim, Derya Biriken, Irem Akin, Seda Altiner, Merve Nur Ceylan, Atakan Tanacan, Huseyin Levent Keskin, Ozlem Moraloglu Tekin, Dilek Sahin

Cytokine. 2022 Jan; 149: 155751. Published online 2021 Oct 30. doi: 10.1016/j.cyto.2021.155751

PMCID:: PMC8556549

Abstract Article PDF–878K

Select item 854376310.

Diagnostic performance of Midkine ratios in fine-needle aspirates for evaluation of Cytologically indeterminate thyroid nodules

Le Zhou, Jinxi Jiang, Yantao Fu, Daqi Zhang, Tong Li, Qingfeng Fu, Chao Yan, Yifan Zhong, Gianlorenzo Dionigi, Nan Liang, Hui Sun

Diagn Pathol. 2021; 16: 92. Published online 2021 Oct 25. doi: 10.1186/s13000-021-01150-y

PMCID:: PMC8543763

Abstract Article PDF–767K

Select item 838805411.

Midkine: Utility as a Predictor of Early Diabetic Nephropathy in Children with Type 1 Diabetes Mellitus

Kotb Abbass Metwalley, Hekma Saad Farghaly, Magda Farghali Gabri, Safwat Mohamed Abdel-Aziz, Asmaa Mohamed Ismail, Duaa Mohamed Raafat, Islam Fathy Elnakeeb

J Clin Res Pediatr Endocrinol. 2021 Sep; 13(3): 293–299. Published online 2021 Aug 23. doi: 10.4274/jcrpe.galenos.2021.2020.0303

PMCID:: PMC8388054

Abstract Article PDF–263K

Select item 746810012.

Serum Midkine, estimated glomerular filtration rate and chronic kidney disease-related events in elderly women: Perth Longitudinal Study of Aging Women

Jeffrey Wang, Joshua R. Lewis, Elizabeth Byrnes, Germaine Wong, Warren D. Raymond, Kun Zhu, Graham R. Robertson, Wai H. Lim, Qi Cao, Richard L. Prince, Vincent W. Lee

Sci Rep. 2020; 10: 14499. Published online 2020 Sep 2. doi: 10.1038/s41598-020-71353-8

PMCID:: PMC7468100

Abstract Article PDF–1.0M

Select item 716345013.

Midkine signaling maintains the self-renewal and tumorigenic capacity of glioma initiating cells

Israel López-Valero, David Dávila, José González-Martínez, Nélida Salvador-Tormo, Mar Lorente, Cristina Saiz-Ladera, Sofía Torres, Estibaliz Gabicagogeascoa, Sonia Hernández-Tiedra, Elena García-Taboada, Marina Mendiburu-Eliçabe, Fátima Rodríguez-Fornés, Rebeca Sánchez-Domínguez, José Carlos Segovia, Pilar Sánchez-Gómez, Ander Matheu, Juan M. Sepúlveda, Guillermo Velasco

Theranostics. 2020; 10(11): 5120–5136. Published online 2020 Apr 6. doi: 10.7150/thno.41450

PMCID:: PMC7163450

Abstract Article PDF–2.8M

Select item 706408714.

Serum Midkine is a clinical significant biomarker for colorectal cancer and associated with poor survival

Marius Kemper, Wiebke Hentschel, Julia‐Kristin Graß, Bjoern‐Ole Stüben, Leonie Konczalla, Tamina Rawnaq, Tarik Ghadban, Jakob R. Izbicki, Matthias Reeh

Cancer Med. 2020 Mar; 9(6): 2010–2018. Published online 2020 Jan 26. doi: 10.1002/cam4.2884

PMCID:: PMC7064087

Abstract Article PDF–621K

Select item 678658515.

Diagnostic accuracy of midkine on hepatocellular carcinoma: A meta-analysis

Bo-han Zhang, Bo Li, Ling-xiang Kong, Lv-nan Yan, Jia-yin Yang

PLoS One. 2019; 14(10): e0223514. Published online 2019 Oct 10. doi: 10.1371/journal.pone.0223514

PMCID:: PMC6786585

Abstract Article PDF–894K

Select item 678403216.

Midkine Is Part of the Antibacterial Activity Released at the Surface of Differentiated Bronchial Epithelial Cells

Sara L. Nordin, Cecilia Andersson, Leif Bjermer, Anders Bjartell, Matthias Mörgelin, Arne Egesten

J Innate Immun. 2013 Jul; 5(5): 519–530. Published online 2013 Feb 2. doi: 10.1159/000346709

PMCID:: PMC6784032

Abstract Article PDF–714K

Select item 673657717.

Midkine Is Elevated After Multiple Trauma and Acts Directly on Human Cardiomyocytes by Altering Their Functionality and Metabolism

Ina Lackner, Birte Weber, Meike Baur, Melanie Haffner-Luntzer, Tim Eiseler, Giorgio Fois, Florian Gebhard, Borna Relja, Ingo Marzi, Roman Pfeifer, Sascha Halvachizadeh, Miriam Lipiski, Nikola Cesarovic, Hans-Christoph Pape, Miriam Kalbitz, TREAT Research Group

Front Immunol. 2019; 10: 1920. Published online 2019 Aug 21. doi: 10.3389/fimmu.2019.01920

PMCID:: PMC6736577

Abstract Article PDF–1022K

Select item 649556218.

Recombinant human midkine stimulates proliferation of articular chondrocytes

Z. H. Zhang, H. X. Li, Y. P. Qi, L. J. Du, S. Y. Zhu, M. Y. Wu, H. L. Lu, Y. Yu, W. Han

Cell Prolif. 2010 Apr; 43(2): 184–194. Published online 2010 Feb 26. doi: 10.1111/j.1365-2184.2010.00668.x

PMCID:: PMC6495562

Abstract Article PDF–771K

Select item 631449119.

Evaluation of Midkine as a Diagnostic Serum Biomarker in Hepatocellular Carcinoma

Wen-Wei Zhu, Jia-Jian Guo, Lei Guo, Hu-Liang Jia, Ming Zhu, Ju-Bo Zhang, Christopher A. Loffredo, Marshonna Forgues, Hua Huang, Xu-Jian Xing, Ning Ren, Qiong-Zhu Dong, Hai-Jun Zhou, Zheng-Gang Ren, Nai-Qing Zhao, Xin Wei Wang, Zhao-You Tang, Lun-Xiu Qin, Qing-Hai Ye

Clin Cancer Res. Author manuscript; available in PMC 2019 Jan 2.

Published in final edited form as: Clin Cancer Res. 2013 Jul 15; 19(14): 3944–3954. Published online 2013 May 29. doi: 10.1158/1078-0432.CCR-12-3363

PMCID:: PMC6314491

Abstract Article PDF–923K

Select item 583005220.

Positive expression of Midkine predicts early recurrence and poor prognosis of initially resectable combined hepatocellular cholangiocarcinoma

Ming-Chun Ma, Yi-Ju Chen, Tai-Jan Chiu, Jui Lan, Chien-Ting Liu, Yi-Ching Chen, Hsin-Ho Tien, Yen-Yang Chen

BMC Cancer. 2018; 18: 227. Published online 2018 Feb 27. doi: 10.1186/s12885-018-4146-7

PMCID:: PMC5830052

Abstract Article PDF–5.9M

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