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Select item 62331601.

ME1 promotes basal-like breast cancer progression and associates with poor prognosis

Ruocen Liao, Guoping Ren, Huixin Liu, Xingyu Chen, Qianhua Cao, Xuebiao Wu, Jun Li, Chenfang Dong

Sci Rep. 2018; 8: 16743. Published online 2018 Nov 13. doi: 10.1038/s41598-018-35106-y

PMCID:: PMC6233160

Article PDF–2.8M

Select item 59898422.

Expression of cytosolic malic enzyme (ME1) is associated with disease progression in human oral squamous cell carcinoma

Chie Nakashima, Kazuhiko Yamamoto, Rina Fujiwara‐Tani, Yi Luo, Sayako Matsushima, Kiyomu Fujii, Hitoshi Ohmori, Tomonori Sasahira, Takamitsu Sasaki, Yasuhiko Kitadai, Tadaaki Kirita, Hiroki Kuniyasu

Cancer Sci. 2018 Jun; 109(6): 2036–2045. Published online 2018 May 1. doi: 10.1111/cas.13594

PMCID:: PMC5989842

Article PDF–1.5M

Select item 56418613.

Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions

Pengbo Yao, Huishan Sun, Chang Xu, Taiqi Chen, Bing Zou, Peng Jiang, Wenjing Du

J Biol Chem. 2017 Oct 13; 292(41): 17113–17120. Published online 2017 Aug 28. doi: 10.1074/jbc.M117.810309

PMCID:: PMC5641861

Article PDF–1.9M

Select item 37775174.

Repressing malic enzyme 1 redirects glucose metabolism, unbalances the redox state, and attenuates migratory and invasive abilities in nasopharyngeal carcinoma cell lines

Fang-Jing Zheng, Hao-Bin Ye, Man-Si Wu, Yi-Fan Lian, Chao-Nan Qian, Yi-Xin Zeng

Chin J Cancer. 2012 Nov; 31(11): 519–531. doi: 10.5732/cjc.012.10088

PMCID:: PMC3777517

Article PDF–1.2M

Select item 35287425.

Biophysical Characterization of the Dimer and Tetramer Interface Interactions of the Human Cytosolic Malic Enzyme

Sujithkumar Murugan, Hui-Chih Hung

PLoS One. 2012; 7(12): e50143. Published online 2012 Dec 21. doi: 10.1371/journal.pone.0050143

PMCID:: PMC3528742

Article PDF–646K

Select item 17625086.

Assignment of the genes for malate oxidoreductase decarboxylating to chromosome 6 and peptidase B and lactate dehydrogenase B to chromosome 12 in man.

T R Chen, F A McMorris, R Creagan, F Ricciuti, J Tischfield, F Ruddle

Am J Hum Genet. 1973 Mar; 25(2): 200–207.

PMCID:: PMC1762508

Summary Page Browse PDF–1.2M

Select item 61551497.

Malic Enzyme 1 (ME1) is pro-oncogenic in Apc^Min/+ mice

Lorenzo M. Fernandes, Ahmed Al-Dwairi, Rosalia C. M. Simmen, Meera Marji, Dustin M. Brown, Sarah W. Jewell, Frank A. Simmen

Sci Rep. 2018; 8: 14268. Published online 2018 Sep 24. doi: 10.1038/s41598-018-32532-w

PMCID:: PMC6155149

Article PDF–3.1M

Select item 59197188.

Tumor-suppressing effects of microRNA-612 in bladder cancer cells by targeting malic enzyme 1 expression

Mengnan Liu, Yifan Chen, Bisheng Huang, Shiyu Mao, Keke Cai, Longsheng Wang, Xudong Yao

Int J Oncol. 2018 Jun; 52(6): 1923–1933. Published online 2018 Mar 29. doi: 10.3892/ijo.2018.4342

PMCID:: PMC5919718

Article PDF–1.9M

Select item 45026409.

Mutant KRAS associated malic enzyme 1 expression is a predictive marker for radiation therapy response in non-small cell lung cancer

Gaurab Chakrabarti

Radiat Oncol. 2015; 10: 145. Published online 2015 Jul 16. doi: 10.1186/s13014-015-0457-x

PMCID:: PMC4502640

Article PDF–813K

Select item 270937710.

Functional Roles of the Tetramer Organization of Malic Enzyme

Ju-Yi Hsieh, Shao-Hung Chen, Hui-Chih Hung

J Biol Chem. 2009 Jul 3; 284(27): 18096–18105. Published online 2009 May 5. doi: 10.1074/jbc.M109.005082

PMCID:: PMC2709377

Article PDF–2.8M

Select item 123492011.

A New Locus for Autosomal Dominant Dilated Cardiomyopathy Identified on Chromosome 6q12-q16

N. Sylvius, F. Tesson, C. Gayet, P. Charron, A. Bénaïche, M. Peuchmaurd, L. Duboscq-Bidot, J. Feingold, J. S. Beckmann, C. Bouchier, M. Komajda

Am J Hum Genet. 2001 Jan; 68(1): 241–246. Published online 2000 Nov 20. doi: 10.1086/316929

PMCID:: PMC1234920

Article PDF–226K

Select item 758274612.

Malic Enzyme 1 Is Associated with Tumor Budding in Oral Squamous Cell Carcinomas

Chie Nakashima, Tadaaki Kirita, Kazuhiko Yamamoto, Shiori Mori, Yi Luo, Takamitsu Sasaki, Kiyomu Fujii, Hitoshi Ohmori, Isao Kawahara, Takuya Mori, Kei Goto, Shingo Kishi, Rina Fujiwara-Tani, Hiroki Kuniyasu

Int J Mol Sci. 2020 Oct; 21(19): 7149. Published online 2020 Sep 28. doi: 10.3390/ijms21197149

PMCID:: PMC7582746

Article PDF–2.5M

Select item 552017113.

MicroRNA-30a attenuates mutant KRAS-driven colorectal tumorigenesis via direct suppression of ME1

Hongxing Shen, Chuan Xing, Kaisa Cui, Yunxiao Li, Jinxiang Zhang, Runlei Du, Xiaodong Zhang, Youjun Li

Cell Death Differ. 2017 Jul; 24(7): 1253–1262. Published online 2017 May 5. doi: 10.1038/cdd.2017.63

PMCID:: PMC5520171

Article PDF–3.2M

Select item 269239714.

Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion

Emma Heart, Gary W. Cline, Leon P. Collis, Rebecca L. Pongratz, Joshua P. Gray, Peter J. S. Smith

Am J Physiol Endocrinol Metab. 2009 Jun; 296(6): E1354–E1362. Published online 2009 Mar 17. doi: 10.1152/ajpendo.90836.2008

PMCID:: PMC2692397

Article

Select item 356150015.

Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence

Peng Jiang, Wenjing Du, Anthony Mancuso, Kathryn E. Wellen, Xiaolu Yang

Nature. Author manuscript; available in PMC 2013 Jul 31.

Published in final edited form as: Nature. 2013 Jan 31; 493(7434): 689–693. Published online 2013 Jan 13. doi: 10.1038/nature11776

PMCID:: PMC3561500

Article PDF–901K

Select item 856401416.

Mitochondrial Fission Factor Is a Novel Interacting Protein of the Critical B Cell Survival Regulator TRAF3 in B Lymphocytes

Yingying Liu, Samantha Gokhale, Jaeyong Jung, Sining Zhu, Chang Luo, Debanjan Saha, Jessie Yanxiang Guo, Huaye Zhang, Saw Kyin, Wei-Xing Zong, Eileen White, Ping Xie

Front Immunol. 2021; 12: 670338. Published online 2021 Oct 20. doi: 10.3389/fimmu.2021.670338

PMCID:: PMC8564014

Article PDF–18M

Select item 312311517.

The BTB and CNC Homology 1 (BACH1) Target Genes Are Involved in the Oxidative Stress Response and in Control of the Cell Cycle

Hans-Jörg Warnatz, Dominic Schmidt, Thomas Manke, Ilaria Piccini, Marc Sultan, Tatiana Borodina, Daniela Balzereit, Wasco Wruck, Alexey Soldatov, Martin Vingron, Hans Lehrach, Marie-Laure Yaspo

J Biol Chem. 2011 Jul 1; 286(26): 23521–23532. Published online 2011 May 9. doi: 10.1074/jbc.M111.220178

PMCID:: PMC3123115

Article PDF–2.2M

Select item 938159018.

DDX39B drives colorectal cancer progression by promoting the stability and nuclear translocation of PKM2

Gang Zhao, Hang Yuan, Qin Li, Jie Zhang, Yafei Guo, Tianyu Feng, Rui Gu, Deqiong Ou, Siqi Li, Kai Li, Ping Lin

Signal Transduct Target Ther. 2022; 7: 275. Published online 2022 Aug 17. doi: 10.1038/s41392-022-01096-7

PMCID:: PMC9381590

Article PDF–8.3M

Select item 743833619.

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer

R. Vatapalli, V. Sagar, Y. Rodriguez, J. C. Zhao, K. Unno, S. Pamarthy, B. Lysy, J. Anker, H. Han, Y. A. Yoo, M. Truica, Z. R. Chalmers, F. Giles, J. Yu, D. Chakravarti, B. Carneiro, S. A. Abdulkadir

Nat Commun. 2020; 11: 4153. Published online 2020 Aug 19. doi: 10.1038/s41467-020-18013-7