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Select item 107244271.

A Ubiquitin‐Dependent Switch on MEF2D Senses Pro‐Metastatic Niche Signals to Facilitate Intrahepatic Metastasis of Liver Cancer

Junyu Xiang, Ni Zhang, Aibei Du, Jinyang Li, Mengyun Luo, Yuzhu Wang, Meng Liu, Luming Yang, Xianfeng Li, Lin Wang, Qin Liu, Dongfeng Chen, Tao Wang, Xiu‐wu Bian, Zhong‐yi Qin, Li Su, Liangzhi Wen, Bin Wang

Adv Sci (Weinh) 2023 Dec; 10(35): 2305550. Published online 2023 Oct 12. doi: 10.1002/advs.202305550

PMCID:: PMC10724427

Abstract Article PDF–6.9M

Select item 103117952.

The transcription factor Mef2d regulates B:T synapse-dependent GC-Tfh differentiation and IL-21-mediated humoral immunity

Ye-Ji Kim, Jeein Oh, Soohan Jung, Chan Johng Kim, Jinyong Choi, Yoon Kyung Jeon, Hyun Jik Kim, Ji-Won Kim, Chang-Hee Suh, Yoontae Lee, Sin-Hyeog Im, Shane Crotty, Youn Soo Choi

Sci Immunol. Author manuscript; available in PMC 2023 Sep 30.

Published in final edited form as: Sci Immunol. 2023 Mar 31; 8(81): eadf2248. Published online 2023 Mar 24. doi: 10.1126/sciimmunol.adf2248

PMCID:: PMC10311795

Abstract Article PDF–3.0M

Select item 87591313.

Transcription factor MEF2D is required for the maintenance of MLL-rearranged acute myeloid leukemia

Lianzhong Zhao, Pengcheng Zhang, Phillip M. Galbo, Jr, Xinyue Zhou, Sajesan Aryal, Shaowei Qiu, Hao Zhang, Yang Zhou, Chunliang Li, Deyou Zheng, Ravi Bhatia, Rui Lu

Blood Adv. 2021 Nov 23; 5(22): 4727–4740. Published online 2021 Nov 22. doi: 10.1182/bloodadvances.2021004469

PMCID:: PMC8759131

Abstract Article PDF–2.3M

Select item 64605664.

A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts

Fabiana H. G. Farias, Johanna Dahlqvist, Sergey V. Kozyrev, Dag Leonard, Maria Wilbe, Sergei N. Abramov, Andrei Alexsson, Gerli R. Pielberg, Helene Hansson-Hamlin, Göran Andersson, Karolina Tandre, Anders A. Bengtsson, Christopher Sjöwall, Elisabet Svenungsson, Iva Gunnarsson, Solbritt Rantapää-Dahlqvist, Ann-Christine Syvänen, Johanna K. Sandling, Maija-Leena Eloranta, Lars Rönnblom, Kerstin Lindblad-Toh

Eur J Hum Genet. 2019 Mar; 27(3): 432–441. Published online 2018 Nov 20. doi: 10.1038/s41431-018-0297-x

PMCID:: PMC6460566

Abstract Article PDF–1.0M

Select item 53661275.

Myocyte enhancer factor 2D provides a cross-talk between chronic inflammation and lung cancer

Hai-xing Zhu, Lin Shi, Yong Zhang, Yi-chun Zhu, Chun-xue Bai, Xiang-dong Wang, Jie-bai Zhou

J Transl Med. 2017; 15: 65. Published online 2017 Mar 24. doi: 10.1186/s12967-017-1168-x

PMCID:: PMC5366127

Abstract Article PDF–2.8M

Select item 38790636.

Loss of MEF2D expression inhibits differentiation and contributes to oncogenesis in rhabdomyosarcoma cells

Meiling Zhang, Jamie Truscott, Judith Davie

Mol Cancer. 2013; 12: 150. Published online 2013 Nov 27. doi: 10.1186/1476-4598-12-150

PMCID:: PMC3879063

Abstract Article PDF–1023K

Select item 99169097.

Dysregulation of Krüppel-like Factor 2 and Myocyte Enhancer Factor 2D Drive Cardiac Microvascular Inflammation and Dysfunction in Diabetes

Mostafa Samak, Andreas Kues, Diana Kaltenborn, Lina Klösener, Matthias Mietsch, Giulia Germena, Rabea Hinkel

Int J Mol Sci. 2023 Feb; 24(3): 2482. Published online 2023 Jan 27. doi: 10.3390/ijms24032482

Correction in:: Int J Mol Sci. 2024 Jan; 25(2): 1058.

PMCID:: PMC9916909

Abstract Article PDF–3.0M

Select item 78599928.

Nucleolar and spindle-associated protein 1 promotes non-small cell lung cancer progression and serves as an effector of myocyte enhancer factor 2D

Bo Ling, Pengya Wei, Juan Xiao, Bingkui Cen, Hong Wei, Xueping Feng, Guangbin Ye, Songbo Li, Zhongwei Zhang, Wei Liang, Suoyi Huang, Wei Huang

Oncol Rep. 2021 Mar; 45(3): 1044–1058. Published online 2020 Dec 30. doi: 10.3892/or.2020.7918

PMCID:: PMC7859992

Abstract Article PDF–2.0M

Select item 30493869.

Direct regulation of complex I by mitochondrial MEF2D is disrupted in a mouse model of Parkinson disease and in human patients

Hua She, Qian Yang, Kennie Shepherd, Yoland Smith, Gary Miller, Claudia Testa, Zixu Mao

J Clin Invest. 2011 Mar 1; 121(3): 930–940. Published online 2011 Feb 14. doi: 10.1172/JCI43871

PMCID:: PMC3049386

Abstract Article PDF–4.2M

Select item 30202710.

Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis

Hong-Duk Youn, Talal A. Chatila, Jun O. Liu

EMBO J. 2000 Aug 15; 19(16): 4323–4331. doi: 10.1093/emboj/19.16.4323

PMCID:: PMC302027

Abstract Article PDF–607K

Select item 827070311.

KDM1A Promotes Immunosuppression in Hepatocellular Carcinoma by Regulating PD-L1 through Demethylating MEF2D

Yonglan Wang, Kun Cao

J Immunol Res. 2021; 2021: 9965099. Published online 2021 Jul 1. doi: 10.1155/2021/9965099

PMCID:: PMC8270703

Abstract Article PDF–4.5M

Select item 695440912.

Different class IIa HDACs repressive complexes regulate specific epigenetic responses related to cell survival in leiomyosarcoma cells

Eros Di Giorgio, Emiliano Dalla, Elisa Franforte, Harikrishnareddy Paluvai, Martina Minisini, Matteo Trevisanut, Raffaella Picco, Claudio Brancolini

Nucleic Acids Res. 2020 Jan 24; 48(2): 646–664. Published online 2019 Nov 22. doi: 10.1093/nar/gkz1120

PMCID:: PMC6954409

Abstract Article PDF–9.6M

Select item 403899813.

Oxidation of Survival Factor MEF2D in Neuronal Death and Parkinson's Disease

Li Gao, Hua She, Wenming Li, Jin Zeng, Jinqiu Zhu, Dean P. Jones, Zixu Mao, Guodong Gao, Qian Yang

Antioxid Redox Signal. 2014 Jun 20; 20(18): 2936–2948. doi: 10.1089/ars.2013.5399

PMCID:: PMC4038998

Abstract Article PDF–863K

Select item 229307914.

Protein Kinase A Represses Skeletal Myogenesis by Targeting Myocyte Enhancer Factor 2D

Min Du, Robert L. S. Perry, Nathaniel B. Nowacki, Joseph W. Gordon, Jahan Salma, Jianzhong Zhao, Arif Aziz, Joseph Chan, K. W. Michael Siu, John C. McDermott

Mol Cell Biol. 2008 May; 28(9): 2952–2970. Published online 2008 Feb 25. doi: 10.1128/MCB.00248-08