PMC Links for Gene (Select 4358) - PMC

Select item 93253471.

Comprehensive Analysis on the Specific Role and Function of Mitochondrial Inner Membrane Protein MPV17 in Liver Hepatocellular Carcinoma

Hanchuan Tao, Cheng Wang, Chongmei Lu, Ning Ma, Yifan Zhu, Shihai Xuan, Xiaojun Zhou

Genet Res (Camb) 2022; 2022: 7236823. Published online 2022 Jul 19. doi: 10.1155/2022/7236823

PMCID:: PMC9325347

Abstract Article PDF–4.5M

Select item 70641942.

MPV17 does not control cancer cell proliferation

Morgane Canonne, Anaïs Wanet, Thuy Truong An Nguyen, Alexis Khelfi, Sophie Ayama-Canden, Martine Van Steenbrugge, Antoine Fattaccioli, Etienne Sokal, Mustapha Najimi, Thierry Arnould, Patricia Renard

PLoS One. 2020; 15(3): e0229834. Published online 2020 Mar 10. doi: 10.1371/journal.pone.0229834

PMCID:: PMC7064194

Abstract Article PDF–1.7M

Select item 63115243.

The mitochondrial inner membrane protein MPV17 prevents uracil accumulation in mitochondrial DNA

Judith R. Alonzo, Chantel Venkataraman, Martha S. Field, Patrick J. Stover

J Biol Chem. 2018 Dec 28; 293(52): 20285–20294. Published online 2018 Nov 1. doi: 10.1074/jbc.RA118.004788

PMCID:: PMC6311524

Abstract Article PDF–1.9M

Select item 45951194.

A novel homozygous MPV17 mutation in two families with axonal sensorimotor polyneuropathy

Yu-Ri Choi, Young Bin Hong, Sung-Chul Jung, Ja Hyun Lee, Ye Jin Kim, Hyung Jun Park, Jinho Lee, Heasoo Koo, Ji-Su Lee, Dong Hwan Jwa, Namhee Jung, So-Youn Woo, Sang-Beom Kim, Ki Wha Chung, Byung-Ok Choi

BMC Neurol. 2015; 15: 179. Published online 2015 Oct 5. doi: 10.1186/s12883-015-0430-1

PMCID:: PMC4595119

Abstract Article PDF–1.5M

Select item 38956325.

Clinical, biochemical, cellular and molecular characterization of mitochondrial DNA depletion syndrome due to novel mutations in the MPV17 gene

Johanna Uusimaa, Julie Evans, Conrad Smith, Anna Butterworth, Kate Craig, Neil Ashley, Chunyan Liao, Janet Carver, Alan Diot, Lorna Macleod, Iain Hargreaves, Abdulrahman Al-Hussaini, Eissa Faqeih, Ali Asery, Mohammed Al Balwi, Wafaa Eyaid, Areej Al-Sunaid, Deirdre Kelly, Indra van Mourik, Sarah Ball, Joanna Jarvis, Arundhati Mulay, Nedim Hadzic, Marianne Samyn, Alastair Baker, Shamima Rahman, Helen Stewart, Andrew AM Morris, Anneke Seller, Carl Fratter, Robert W Taylor, Joanna Poulton

Eur J Hum Genet. 2014 Feb; 22(2): 184–191. Published online 2013 May 29. doi: 10.1038/ejhg.2013.112

PMCID:: PMC3895632

Abstract Article PDF–974K

Select item 15595526.

Navajo Neurohepatopathy Is Caused by a Mutation in the MPV17 Gene

Charalampos L. Karadimas, Tuan H. Vu, Stephen A. Holve, Penelope Chronopoulou, Catarina Quinzii, Stanley D. Johnsen, Janice Kurth, Elizabeth Eggers, Lluis Palenzuela, Kurenai Tanji, Eduardo Bonilla, Darryl C. De Vivo, Salvatore DiMauro, Michio Hirano

Am J Hum Genet. 2006 Sep; 79(3): 544–548. Published online 2006 Jun 28. doi: 10.1086/506913

PMCID:: PMC1559552

Abstract Article PDF–288K

Select item 47118917.

MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria

Ilaria Dalla Rosa, Yolanda Cámara, Romina Durigon, Chloe F. Moss, Sara Vidoni, Gokhan Akman, Lilian Hunt, Mark A. Johnson, Sarah Grocott, Liya Wang, David R. Thorburn, Michio Hirano, Joanna Poulton, Robert W. Taylor, Greg Elgar, Ramon Martí, Peter Voshol, Ian J. Holt, Antonella Spinazzola

PLoS Genet. 2016 Jan; 12(1): e1005779. Published online 2016 Jan 13. doi: 10.1371/journal.pgen.1005779

PMCID:: PMC4711891

Abstract Article PDF–4.0M

Select item 44479608.

The Human Mitochondrial DNA Depletion Syndrome Gene MPV17 Encodes a Non-selective Channel That Modulates Membrane Potential

Vasily D. Antonenkov, Antti Isomursu, Daniela Mennerich, Miia H. Vapola, Hans Weiher, Thomas Kietzmann, J. Kalervo Hiltunen

J Biol Chem. 2015 May 29; 290(22): 13840–13861. Published online 2015 Apr 10. doi: 10.1074/jbc.M114.608083

PMCID:: PMC4447960

Abstract Article PDF–3.7M

Select item 3954609.

The glomerulosclerosis gene Mpv17 encodes a peroxisomal protein producing reactive oxygen species.

R M Zwacka, A Reuter, E Pfaff, J Moll, K Gorgas, M Karasawa, H Weiher

EMBO J. 1994 Nov 1; 13(21): 5129–5134. doi: 10.1002/j.1460-2075.1994.tb06842.x

PMCID:: PMC395460

Summary Page Browse PDF–1.8M

Select item 301760210.

Identification of rare DNA variants in mitochondrial disorders with improved array-based sequencing

Wenyi Wang, Peidong Shen, Sreedevi Thiyagarajan, Shengrong Lin, Curtis Palm, Rita Horvath, Thomas Klopstock, David Cutler, Lynn Pique, Iris Schrijver, Ronald W. Davis, Michael Mindrinos, Terence P. Speed, Curt Scharfe

Nucleic Acids Res. 2011 Jan; 39(1): 44–58. Published online 2010 Sep 15. doi: 10.1093/nar/gkq750

PMCID:: PMC3017602

Abstract Article PDF–1.4M

Select item 910630311.

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 499245612.

Mitochondrial protein interaction mapping identifies new regulators of respiratory chain function

Brendan J. Floyd, Emily M. Wilkerson, Mike T. Veling, Catie E. Minogue, Chuanwu Xia, Emily T. Beebe, Russell L. Wrobel, Holly Cho, Laura S. Kremer, Charlotte L. Alston, Katarzyna A. Gromek, Brendan K. Dolan, Arne Ulbrich, Jonathan A. Stefely, Sarah L. Bohl, Kelly M. Werner, Adam Jochem, Michael S. Westphall, Jarred W. Rensvold, Robert W. Taylor, Holger Prokisch, Jung-Ja P. Kim, Joshua J. Coon, David J. Pagliarini

Mol Cell. Author manuscript; available in PMC 2017 Aug 18.

Published in final edited form as: Mol Cell. 2016 Aug 18; 63(4): 621–632. Published online 2016 Aug 4. doi: 10.1016/j.molcel.2016.06.033

PMCID:: PMC4992456

Abstract Article PDF–1.7M

Select item 488219013.

Widespread expansion of protein interaction capabilities by alternative splicing

Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal

Cell. Author manuscript; available in PMC 2017 Feb 11.

Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029

PMCID:: PMC4882190

Abstract Article PDF–1.9M

Select item 933831314.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 563060015.

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell

Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8

PMCID:: PMC5630600

Abstract Article PDF–2.3M

Select item 294347616.

Genetic Variants in Nuclear-Encoded Mitochondrial Genes Influence AIDS Progression

Sher L. Hendrickson, James A. Lautenberger, Leslie Wei Chinn, Michael Malasky, Efe Sezgin, Lawrence A. Kingsley, James J. Goedert, Gregory D. Kirk, Edward D. Gomperts, Susan P. Buchbinder, Jennifer L. Troyer, Stephen J. O'Brien

PLoS One. 2010; 5(9): e12862. Published online 2010 Sep 21. doi: 10.1371/journal.pone.0012862

PMCID:: PMC2943476

Abstract Article PDF–461K

Select item 347780417.

A Census of Human Soluble Protein Complexes

Pierre C. Havugimana, G. Traver Hart, Tamás Nepusz, Haixuan Yang, Andrei L. Turinsky, Zhihua Li, Peggy I. Wang, Daniel R. Boutz, Vincent Fong, Sadhna Phanse, Mohan Babu, Stephanie A. Craig, Pingzhao Hu, Cuihong Wan, James Vlasblom, Vaqaarun-Nisa Dar, Alexander Bezginov, Gregory W. Clark, Gabriel C. Wu, Shoshana J. Wodak, Elisabeth R.M. Tillier, Alberto Paccanaro, Edward M. Marcotte, Andrew Emili

Cell. Author manuscript; available in PMC 2013 Aug 31.

Published in final edited form as: Cell. 2012 Aug 31; 150(5): 1068–1081. doi: 10.1016/j.cell.2012.08.011