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Select item 95454721.

Liver pathology and biochemistry in patients with mutations in TRIM37 gene (Mulibrey nanism)

Johanna Sivunen, Susann Karlberg, Reetta Kivisaari, Jouko Lohi, Niklas Karlberg, Eero Jokinen, Taisto Sarkola, Timo Jahnukainen, Marita Lipsanen‐Nyman, Hannu Jalanko

Liver Int. 2022 Jun; 42(6): 1369–1378. Published online 2022 Mar 8. doi: 10.1111/liv.15213

PMCID:: PMC9545472

Abstract Article PDF–740K

Select item 88356692.

TRIM37 Promotes Pancreatic Cancer Progression through Modulation of Cell Growth, Migration, Invasion, and Tumor Immune Microenvironment

Tuyen Thi Do, Chun-Chieh Yeh, Guo-Wei Wu, Chia-Chen Hsu, Hung-Chih Chang, Hui-Chen Chen

Int J Mol Sci. 2022 Feb; 23(3): 1176. Published online 2022 Jan 21. doi: 10.3390/ijms23031176

PMCID:: PMC8835669

Abstract Article PDF–5.9M

Select item 82044443.

TRIM37 orchestrates renal cell carcinoma progression via histone H2A ubiquitination-dependent manner

Chenkui Miao, Chao Liang, Pu Li, Bianjiang Liu, Chao Qin, Han Yuan, Yiyang Liu, Jundong Zhu, Yankang Cui, Aiming Xu, Shangqian Wang, Shifeng Su, Jie Li, Pengfei Shao, Zengjun Wang

J Exp Clin Cancer Res. 2021; 40: 195. Published online 2021 Jun 15. doi: 10.1186/s13046-021-01980-0

PMCID:: PMC8204444

Abstract Article PDF–4.9M

Select item 78406774.

Knockdown of Tripartite Motif-Containing Protein 37 (TRIM37) Inhibits the Proliferation and Tumorigenesis in Colorectal Cancer Cells

Ping Zhao, Hai-Tao Guan, Zhi-Jun Dai, Yu-Guang Ma, Xiao-Xu Liu, Xi-Jing Wang

Oncol Res. 2017; 25(1): 115–122. Published online 2017 Jan 2. doi: 10.3727/096504016X14732772150181

PMCID:: PMC7840677

Abstract Article PDF–6.1M

Select item 77318975.

Oncogenic TRIM37 links chemoresistance and metastatic fate in triple-negative breast cancer

Piotr Przanowski, Song Lou, Rachisan Djiake Tihagam, Tanmoy Mondal, Caroline Conlan, Gururaj Shivange, Ilyas Saltani, Chandrajeet Singh, Kun Xing, Benjamin B. Morris, Marty W. Mayo, Luis Teixeira, Jacqueline Lehmann-Che, Jogender Tushir-Singh, Sanchita Bhatnagar

Cancer Res. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: Cancer Res. 2020 Nov 1; 80(21): 4791–4804. Published online 2020 Aug 27. doi: 10.1158/0008-5472.CAN-20-1459

PMCID:: PMC7731897

Abstract Article PDF–2.6M

Select item 53673636.

TRIM37 promotes epithelial-mesenchymal transition in colorectal cancer

Cheng-En Hu, Jun Gan

Mol Med Rep. 2017 Mar; 15(3): 1057–1062. Published online 2017 Jan 16. doi: 10.3892/mmr.2017.6125

PMCID:: PMC5367363

Abstract Article PDF–1.2M

Select item 39734827.

Anti-HIV-1 activity of Trim 37

Azah A. Tabah, Keith Tardif, Louis M. Mansky

J Gen Virol. 2014 Apr; 95(Pt 4): 960–967. doi: 10.1099/vir.0.057653-0

PMCID:: PMC3973482

Abstract Article PDF–565K

Select item 17124678.

Assignment of the mulibrey nanism gene to 17q by linkage and linkage-disequilibrium analysis.

K Avela, M Lipsanen-Nyman, J Perheentupa, C Wallgren-Pettersson, S Marchand, S Fauré, P Sistonen, A de la Chapelle, A E Lehesjoki

Am J Hum Genet. 1997 Apr; 60(4): 896–902.

PMCID:: PMC1712467

Summary Page Browse PDF–1.1M

Select item 100091019.

TRIM37 interacts with PTEN to promote the growth of human T-cell acute lymphocytic leukemia cells through regulating PI3K/AKT pathway

Honglan Qu, HASEN Gao-wa, Yanyan Hou, Mengwei Ren, Jun Li, Baoshong Jing, YanDan Du

Front Oncol. 2022; 12: 1016725. Published online 2023 Feb 27. doi: 10.3389/fonc.2022.1016725

PMCID:: PMC10009101

Abstract Article PDF–7.4M

Select item 963330210.

Metformin inhibits the proliferation and invasion of ovarian cancer cells by suppressing tripartite motif‐containing 37‐induced tumor necrosis factor receptor‐associated factor 2 ubiquitination

Ya Zheng, Haiyan Zhang, Hong Sun

Cancer Sci. 2022 Nov; 113(11): 3776–3786. Published online 2022 Sep 3. doi: 10.1111/cas.15524

PMCID:: PMC9633302

Abstract Article PDF–5.1M

Select item 893022911.

Modified Yuejuwan Inhibited Cholesterol Accumulation and Inflammation in THP-1 Macrophage-Derived Foam Cells by Inhibiting the Activity of the TRIM37/TRAF2/NF-κB Pathway

Mingtai Gui, Lei Yao, Bo Lu, Jianhua Li, Jing Wang, Xunjie Zhou, Deyu Fu

Evid Based Complement Alternat Med. 2022; 2022: 6400517. Published online 2022 Mar 10. doi: 10.1155/2022/6400517

PMCID:: PMC8930229

Abstract Article PDF–1.1M

Select item 812700612.

TRIM37 prevents formation of condensate-organized ectopic spindle poles to ensure mitotic fidelity

Franz Meitinger, Dong Kong, Midori Ohta, Arshad Desai, Karen Oegema, Jadranka Loncarek

J Cell Biol. 2021 Jul 5; 220(7): e202010180. Published online 2021 May 13. doi: 10.1083/jcb.202010180

PMCID:: PMC8127006

Abstract Article PDF–9.3M

Select item 787014113.

TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin

Fernando R Balestra, Andrés Domínguez-Calvo, Benita Wolf, Coralie Busso, Alizée Buff, Tessa Averink, Marita Lipsanen-Nyman, Pablo Huertas, Rosa M Ríos, Pierre Gönczy

eLife. 2021; 10: e62640. Published online 2021 Jan 25. doi: 10.7554/eLife.62640

PMCID:: PMC7870141

Abstract Article PDF–4.8M

Select item 750118814.

TRIM37 controls cancer-specific vulnerability to PLK4 inhibition

Franz Meitinger, Midori Ohta, Kian-Yong Lee, Sadanori Watanabe, Robert L. Davis, John V. Anzola, Ruth Kabeche, David Jenkins, Andrew K. Shiau, Arshad Desai, Karen Oegema

Nature. Author manuscript; available in PMC 2021 Mar 9.

Published in final edited form as: Nature. 2020 Sep; 585(7825): 440–446. Published online 2020 Sep 9. doi: 10.1038/s41586-020-2710-1

PMCID:: PMC7501188

Abstract Article PDF–3.8M

Select item 729745515.

Knockdown of TRIM37 Promotes Apoptosis and Suppresses Tumor Growth in Gastric Cancer by Inactivation of the ERK1/2 Pathway

Hongyi Zhu, Yuanwen Chen, Jie Zhang, Changlin Qian, Weiqing Qiu, Huojian Shen, Zhiyong Shen

Onco Targets Ther. 2020; 13: 5479–5491. Published online 2020 Jun 12. doi: 10.2147/OTT.S233906

Retraction in:: Onco Targets Ther. 2024; 17: 765–766.

PMCID:: PMC7297455

Abstract Article

Select item 44759616.

The TRIM37 Gene Encodes a Peroxisomal RING-B-Box-Coiled-Coil Protein: Classification of Mulibrey Nanism as a New Peroxisomal Disorder

Jukka Kallijärvi, Kristiina Avela, Marita Lipsanen-Nyman, Ismo Ulmanen, Anna-Elina Lehesjoki

Am J Hum Genet. 2002 May; 70(5): 1215–1228. Published online 2002 Apr 5. doi: 10.1086/340256

PMCID:: PMC447596

Abstract Article PDF–1.1M

Select item 929507417.

TRIM37 Augments AP-2γ Transcriptional Activity and Cellular Localization via K63-linked Ubiquitination to Drive Breast Cancer Progression

Guimei Cui, Zhuoran Gao, Shiehong Chang, Nitin Narwade, Yitian Chen, Barun Poudel, Kate M. K. Lei, Weibo Zhang, Gang Li, Terence C. W. Poon, Edwin Cheung

Int J Biol Sci. 2022; 18(11): 4316–4328. Published online 2022 Jul 4. doi: 10.7150/ijbs.69466

PMCID:: PMC9295074

Abstract Article PDF–2.7M

Select item 613556918.

TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axis

Wei Wang, Zhijie Xia, Jean-Claude Farré, Suresh Subramani

Autophagy. 2018; 14(9): 1574–1585. Published online 2018 Aug 21. doi: 10.1080/15548627.2018.1463120

PMCID:: PMC6135569

Abstract Article PDF–2.3M

Select item 558415619.

TRIM37, a novel E3 ligase for PEX5-mediated peroxisomal matrix protein import

Wei Wang, Zhi-Jie Xia, Jean-Claude Farré, Suresh Subramani

J Cell Biol. 2017 Sep 4; 216(9): 2843–2858. doi: 10.1083/jcb.201611170

PMCID:: PMC5584156

Abstract Article PDF–2.7M

Select item 426932520.

TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein

Sanchita Bhatnagar, Claude Gazin, Lynn Chamberlain, Jianhong Ou, Xiaochun Zhu, Jogender S. Tushir, Ching-Man Virbasius, Ling Lin, Lihua J. Zhu, Narendra Wajapeyee, Michael R. Green

Nature. Author manuscript; available in PMC 2015 Jun 4.

Published in final edited form as: Nature. 2014 Dec 4; 516(7529): 116–120. Published online 2014 Nov 24. doi: 10.1038/nature13955

PMCID:: PMC4269325

Abstract Article PDF–5.2M

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PMC Links for Gene (Select 4591) (61)
PMC
E3 ubiquitin-protein ligase TRIM37 isoform c [Homo sapiens]
E3 ubiquitin-protein ligase TRIM37 isoform c [Homo sapiens]
gi|1005261091|ref|NP_001307918.1|

Protein
PREDICTED: Homo sapiens tripartite motif containing 37 (TRIM37), transcript vari...
PREDICTED: Homo sapiens tripartite motif containing 37 (TRIM37), transcript variant X12, mRNA
gi|2217312044|ref|XM_047436109.1|

Nucleotide
E3 ubiquitin-protein ligase TRIM37 isoform X22 [Homo sapiens]
E3 ubiquitin-protein ligase TRIM37 isoform X22 [Homo sapiens]
gi|1034599829|ref|XP_016880158.1|

Protein
E3 ubiquitin-protein ligase TRIM37 isoform X8 [Homo sapiens]
E3 ubiquitin-protein ligase TRIM37 isoform X8 [Homo sapiens]
gi|2462555439|ref|XP_054172180.1|

Protein

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