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Select item 106436561.

PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation

Chiaki Inoue, Kojiro Mukai, Tatsuyuki Matsudaira, Jun Nakayama, Nozomu Kono, Junken Aoki, Hiroyuki Arai, Yasunori Uchida, Tomohiko Taguchi

Sci Rep. 2023; 13: 19740. Published online 2023 Nov 13. doi: 10.1038/s41598-023-47138-0

PMCID:: PMC10643656

Abstract Article PDF–4.1M

Select item 96235192.

MYPT1 inhibits the metastasis of renal clear cell carcinoma via the MAPK8/N‐cadherin pathway

Qingling Xie, Ren Liu, Zhihao Zou, Yuanfa Feng, Yiqiao Huang, Guibin Xu, Wei Sun, Yuxiang Liang, Weide Zhong

FEBS Open Bio. 2022 Nov; 12(11): 2083–2095. Published online 2022 Sep 27. doi: 10.1002/2211-5463.13487

PMCID:: PMC9623519

Abstract Article PDF–2.6M

Select item 93675443.

Complex Transcriptional Profiles of the PPP1R12A Gene in Cells of the Circulatory System as Revealed by In Silico Analysis and Reverse Transcription PCR

Paulo André Saldanha, Israel Olapeju Bolanle, Timothy Martin Palmer, Leonid Leonidovich Nikitenko, Francisco Rivero

Cells. 2022 Aug; 11(15): 2315. Published online 2022 Jul 27. doi: 10.3390/cells11152315

PMCID:: PMC9367544

Abstract Article PDF–9.0M

Select item 80780534.

A Comparison of Adult Rhabdomyosarcoma and High Grade Neuroendocrine Carcinoma of the Urinary Bladder Reveals Novel PPP1R12A Fusions in Rhabdomyosarcoma

Sounak Gupta, Carlos P. Sosa, Farhad Kosari, Andrew Folpe, Kaustubh N. Bhinge, Lin Yang, Alireza Agahi, Sarah H. Johnson, Igor Frank, Stephen A. Boorjian, Donna E. Hansel, Hikmat A. Al-Ahmadie, Victor E. Reuter, George Vasmatzis, Rafael E. Jimenez, Loren Herrera-Hernandez, John C. Cheville

Hum Pathol. Author manuscript; available in PMC 2021 Apr 27.

Published in final edited form as: Hum Pathol. 2019 Jun; 88: 48–59. Published online 2019 Apr 1. doi: 10.1016/j.humpath.2019.03.007

PMCID:: PMC8078053

Abstract Article PDF–5.4M

Select item 72472985.

O-GlcNAcylation of myosin phosphatase targeting subunit 1 (MYPT1) dictates timely disjunction of centrosomes

Caifei Liu, Yingxin Shi, Jie Li, Xuewen Liu, Zhikai Xiahou, Zhongping Tan, Xing Chen, Jing Li

J Biol Chem. 2020 May 22; 295(21): 7341–7349. Published online 2020 Apr 15. doi: 10.1074/jbc.RA119.012401

PMCID:: PMC7247298

Abstract Article PDF–1.6M

Select item 63023496.

Decreased Expression of MYPT1 Contributes to Tumor Angiogenesis and Poor Patient Prognosis in Human Prostate Cancer

Y. Liang, Y. Zhuo, Z. Lin, F. Jiang, Q. Dai, J. Lu, W. Dong, X. Zhu, Z. Han, W. Zhong

Curr Mol Med. 2018 Feb; 18(2): 100–108. Published online 2018 Feb. doi: 10.2174/1566524018666180705111342

PMCID:: PMC6302349

Abstract Article PDF–5.2M

Select item 59373607.

Overexpression of Myosin Phosphatase Target Subunit 1 (MYPT1) Inhibits Tumor Progression and Metastasis of Gastric Cancer

Fengyong Wang, Yuanshui Sun

Med Sci Monit. 2018; 24: 2508–2517. Published online 2018 Apr 24. doi: 10.12659/MSM.906852

PMCID:: PMC5937360

Abstract Article PDF–965K

Select item 53643788.

Diversity and plasticity in signaling pathways that regulate smooth muscle responsiveness: Paradigms and paradoxes for the myosin phosphatase, the master regulator of smooth muscle contraction

Masumi Eto, Toshio Kitazawa

J Smooth Muscle Res. 2017; 53: 1–19. Published online 2017 Mar 3. doi: 10.1540/jsmr.53.1

PMCID:: PMC5364378

Abstract Article PDF–2.3M

Select item 40102569.

Reconstituted Human Myosin Light Chain Phosphatase Reveals Distinct Roles of Two Inhibitory Phosphorylation Sites of the Regulatory Subunit, MYPT1

Mukta Khasnis, Akiko Nakatomi, Kristyn Gumpper, Masumi Eto

Biochemistry. 2014 Apr 29; 53(16): 2701–2709. Published online 2014 Apr 8. doi: 10.1021/bi5001728

PMCID:: PMC4010256

Abstract Article PDF–2.4M

Select item 381481910.

Differential vasodilation of human placental and myometrial arteries related to myofilament Ca²⁺-desensitization and the expression of Hsp20 but not MYPT1

A.C. Dordea, M. Sweeney, J. Taggart, J. Lartey, H. Wessel, S.C. Robson, M.J. Taggart

Mol Hum Reprod. 2013 Nov; 19(11): 727–736. Published online 2013 Jun 16. doi: 10.1093/molehr/gat045

PMCID:: PMC3814819

Abstract Article PDF–651K

Select item 369571311.

Molecular Characterization of Myosin Phosphatase in Endothelium

Kyung-mi Kim, Csilla Csortos, Istvan Czikora, David Fulton, Nagavedi S. Umapathy, Gabor Olah, Alexander D. Verin

J Cell Physiol. Author manuscript; available in PMC 2013 Jun 28.

Published in final edited form as: J Cell Physiol. 2012 Apr; 227(4): 1701–1708. doi: 10.1002/jcp.22894

PMCID:: PMC3695713

Abstract Article PDF–1.4M

Select item 336704812.

Site-Specific Phosphorylation of Protein Phosphatase 1 Regulatory Subunit 12A Stimulated or Suppressed by Insulin

Alex Chao, Xiangmin Zhang, Danjun Ma, Paul Langlais, Moulun Luo, Lawrence J. Mandarino, Morgan Zingsheim, Kimberly Pham, James Dillon, Zhengping Yi

J Proteomics. Author manuscript; available in PMC 2013 Jun 18.

Published in final edited form as: J Proteomics. 2012 Jun 18; 75(11): 3342–3350. Published online 2012 Apr 6. doi: 10.1016/j.jprot.2012.03.043

PMCID:: PMC3367048

Abstract Article PDF–1.8M

Select item 306053313.

Myosin Phosphatase-targeting Subunit 1 Controls Chromatid Segregation

Fumio Matsumura, Yoshihiko Yamakita, Shigeko Yamashiro

J Biol Chem. 2011 Mar 25; 286(12): 10825–10833. Published online 2011 Jan 20. doi: 10.1074/jbc.M110.169722

PMCID:: PMC3060533

Abstract Article PDF–4.0M

Select item 279662814.

Solution structure of the inhibitory phosphorylation domain of myosin phosphatase targeting subunit 1

Shunsuke Mori, Ryou Iwaoka, Masumi Eto, Shin-ya Ohki

Proteins. Author manuscript; available in PMC 2010 Nov 15.

Published in final edited form as: Proteins. 2009 Nov 15; 77(3): 732–735. doi: 10.1002/prot.22529

PMCID:: PMC2796628

Article PDF–343K

Select item 275588115.

Phosphorylation-dependent Autoinhibition of Myosin Light Chain Phosphatase Accounts for Ca²⁺ Sensitization Force of Smooth Muscle Contraction

Alexander Khromov, Nandini Choudhury, Andra S. Stevenson, Avril V. Somlyo, Masumi Eto

J Biol Chem. 2009 Aug 7; 284(32): 21569–21579. Published online 2009 Jun 15. doi: 10.1074/jbc.M109.019729

PMCID:: PMC2755881

Abstract Article PDF–1.9M

Select item 819128916.

O-GlcNAc modification of MYPT1 modulates lysophosphatidic acid–induced cell contraction in fibroblasts

Murielle M. Morales, Nichole J. Pedowitz, Matthew R. Pratt

J Biol Chem. 2021 Jan-Jun; 296: 100800. Published online 2021 May 19. doi: 10.1016/j.jbc.2021.100800

PMCID:: PMC8191289

Abstract Article PDF–2.6M

Select item 699744617.

MYPT1 Down-regulation by Lipopolysaccharide-SIAH1/2 E3 Ligase-Ubiquitin-Proteasomal Degradation Contributes to Colonic Obstruction of Hirschsprung Disease

W. Zhao, P. Wang, W. He, T. Tao, H. Li, Y. Li, W. Jiang, J. Sun, X. Ge, X. Chen, Y. Zheng, L. Wei, C. Chen, Y. Wang, C. Li, H. Chen, B. Yao, W. Tang, M. Zhu

Cell Mol Gastroenterol Hepatol. 2020; 9(2): 345–347.e6. Published online 2019 Nov 20. doi: 10.1016/j.jcmgh.2019.11.003

PMCID:: PMC6997446

Article PDF–3.0M

Select item 695456818.

Downregulation of MYPT1 increases tumor resistance in ovarian cancer by targeting the Hippo pathway and increasing the stemness

Sandra Muñoz-Galván, Blanca Felipe-Abrio, Eva M. Verdugo-Sivianes, Marco Perez, Manuel P. Jiménez-García, Elisa Suarez-Martinez, Purificacion Estevez-Garcia, Amancio Carnero

Mol Cancer. 2020; 19: 7. Published online 2020 Jan 11. doi: 10.1186/s12943-020-1130-z