PMC Links for Gene (Select 4838) - PMC

Result Filters

Links from Gene

Items: 1 to 20 of 77

<< First< Prev

Page of 4

Select item 109888271.

NODAL variants are associated with a continuum of laterality defects from simple D-transposition of the great arteries to heterotaxy

Zain Dardas, Jawid M. Fatih, Angad Jolly, Moez Dawood, Haowei Du, Christopher M. Grochowski, Edward G. Jones, Shalini N. Jhangiani, Xander H. T. Wehrens, Pengfei Liu, Weimin Bi, Eric Boerwinkle, Jennifer E. Posey, Donna M. Muzny, Richard A. Gibbs, James R. Lupski, Zeynep Coban-Akdemir, Shaine A. Morris

Genome Med. 2024; 16: 53. Published online 2024 Apr 3. doi: 10.1186/s13073-024-01312-9

PMCID:: PMC10988827

Abstract Article PDF–2.7M

Select item 87899052.

Nodal is a short-range morphogen with activity that spreads through a relay mechanism in human gastruloids

Lizhong Liu, Anastasiia Nemashkalo, Luisa Rezende, Ji Yoon Jung, Sapna Chhabra, M. Cecilia Guerra, Idse Heemskerk, Aryeh Warmflash

Nat Commun. 2022; 13: 497. Published online 2022 Jan 25. doi: 10.1038/s41467-022-28149-3

PMCID:: PMC8789905

Abstract Article PDF–8.6M

Select item 85838383.

Normal Skin Cells Increase Aggressiveness of Cutaneous Melanoma by Promoting Epithelial-to-Mesenchymal Transition via Nodal and Wnt Activity

Gustavo Untiveros, Lindsay Dezi, Megan Gillette, Julia Sidor, Luigi Strizzi

Int J Mol Sci. 2021 Nov; 22(21): 11719. Published online 2021 Oct 29. doi: 10.3390/ijms222111719

PMCID:: PMC8583838

Abstract Article PDF–2.0M

Select item 80416634.

Embryonic protein NODAL regulates the breast tumor microenvironment by reprogramming cancer-derived secretomes

Dylan Dieters-Castator, Paola M. Dantonio, Matt Piaseczny, Guihua Zhang, Jiahui Liu, Miljan Kuljanin, Stephen Sherman, Michael Jewer, Katherine Quesnel, Eun Young Kang, Martin Köbel, Gabrielle M. Siegers, Andrew Leask, David Hess, Gilles Lajoie, Lynne-Marie Postovit

Neoplasia. 2021 Apr; 23(4): 375–390. Published online 2021 Mar 27. doi: 10.1016/j.neo.2021.02.004

PMCID:: PMC8041663

Abstract Article PDF–3.5M

Select item 73190875.

Aberrantly Expressed Embryonic Protein NODAL Alters Breast Cancer Cell Susceptibility to γδ T Cell Cytotoxicity

Gabrielle M. Siegers, Indrani Dutta, Eun Young Kang, Jing Huang, Martin Köbel, Lynne-Marie Postovit

Front Immunol. 2020; 11: 1287. Published online 2020 Jun 19. doi: 10.3389/fimmu.2020.01287

PMCID:: PMC7319087

Abstract Article PDF–1.3M

Select item 68227786.

High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gastrulation–associated versus preneurulation-associated fate patterning

Mukul Tewary, Dominika Dziedzicka, Joel Ostblom, Laura Prochazka, Nika Shakiba, Tiam Heydari, Daniel Aguilar-Hidalgo, Curtis Woodford, Elia Piccinini, David Becerra-Alonso, Alice Vickers, Blaise Louis, Nafees Rahman, Davide Danovi, Mieke Geens, Fiona M. Watt, Peter W. Zandstra

PLoS Biol. 2019 Oct; 17(10): e3000081. Published online 2019 Oct 21. doi: 10.1371/journal.pbio.3000081

PMCID:: PMC6822778

Abstract Article PDF–5.7M

Select item 67336307.

Nodal pathway activation due to Akt1 suppression is a molecular switch for prostate cancer cell epithelial-to-mesenchymal transition and metastasis

Abdulrahman Alwhaibi, Arti Verma, Sandeep Artham, Mir S. Adil, Payaningal R. Somanath

Biochem Pharmacol. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Biochem Pharmacol. 2019 Oct; 168: 1–13. Published online 2019 Jun 14. doi: 10.1016/j.bcp.2019.06.010

PMCID:: PMC6733630

Abstract Article PDF–2.1M

Select item 67095488.

Downregulation of Nodal inhibits metastatic progression in retinoblastoma

Laura Asnaghi, David T. White, Lynn Yoon, Antoinette Price, Grace Y. Lee, Arpan Sahoo, Jeff S. Mumm, Charles G. Eberhart

Acta Neuropathol Commun. 2019; 7: 137. Published online 2019 Aug 26. doi: 10.1186/s40478-019-0785-4

PMCID:: PMC6709548

Abstract Article PDF–2.2M

Select item 64482499.

Nodal induces apoptosis and inhibits proliferation in ovarian endometriosis-clear cell carcinoma lesions

Rinako Miura, Ako Yokoi, Toshihide Matsumoto, Yasuko Oguri, Miki Hashimura, Masataka Tochimoto, Sabine Kajita, Makoto Saegusa

BMC Cancer. 2019; 19: 308. Published online 2019 Apr 3. doi: 10.1186/s12885-019-5539-y

PMCID:: PMC6448249

Abstract Article PDF–8.9M

Select item 607798510.

Self-organization of a human organizer by combined WNT and NODAL signalling

I. Martyn, T.Y. Kanno, A. Ruzo, E.D. Siggia, A.H. Brivanlou

Nature. Author manuscript; available in PMC 2018 Nov 23.

Published in final edited form as: Nature. 2018 Jun; 558(7708): 132–135. Published online 2018 May 23. doi: 10.1038/s41586-018-0150-y

PMCID:: PMC6077985

Abstract Article PDF–4.0M

Select item 554878011.

Single cardiomyocyte nuclear transcriptomes reveal a lincRNA-regulated de-differentiation and cell cycle stress-response in vivo

Kelvin See, Wilson L. W. Tan, Eng How Lim, Zenia Tiang, Li Ting Lee, Peter Y. Q. Li, Tuan D. A. Luu, Matthew Ackers-Johnson, Roger S. Foo

Nat Commun. 2017; 8: 225. Published online 2017 Aug 9. doi: 10.1038/s41467-017-00319-8

PMCID:: PMC5548780

Abstract Article PDF–4.4M

Select item 502528112.

Nodal promotes invasive phenotypes via a Mitogen Activated Protein Kinase-dependent pathway

DF Quail, G Zhang, SD Findlay, DA Hess, LM Postovit

Oncogene. Author manuscript; available in PMC 2016 Sep 15.

Published in final edited form as: Oncogene. 2014 Jan 23; 33(4): 461–473. Published online 2013 Jan 21. doi: 10.1038/onc.2012.608

PMCID:: PMC5025281

Abstract Article PDF–1.5M

Select item 488923213.

Nodal expression in triple-negative breast cancer: Cellular effects of its inhibition following doxorubicin treatment

Thomas M. Bodenstine, Grace S. Chandler, David W. Reed, Naira V. Margaryan, Alina Gilgur, Janis Atkinson, Nida Ahmed, Matthew Hyser, Elisabeth A. Seftor, Luigi Strizzi, Mary J. C. Hendrix

Cell Cycle. 2016; 15(9): 1295–1302. Published online 2016 Mar 23. doi: 10.1080/15384101.2016.1160981

PMCID:: PMC4889232

Abstract Article PDF–898K

Select item 482315514.

Plasticity underlies tumor progression: Role of Nodal signaling

Thomas M. Bodenstine, Grace S. Chandler, Richard E. B. Seftor, Elisabeth A. Seftor, Mary J. C. Hendrix

Cancer Metastasis Rev. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Cancer Metastasis Rev. 2016 Mar; 35(1): 21–39. doi: 10.1007/s10555-016-9605-5

PMCID:: PMC4823155

Abstract Article PDF–1.7M

Select item 452045415.

BMP Inhibition in Seminomas Initiates Acquisition of Pluripotency via NODAL Signaling Resulting in Reprogramming to an Embryonal Carcinoma

Daniel Nettersheim, Sina Jostes, Rakesh Sharma, Simon Schneider, Andrea Hofmann, Humberto J. Ferreira, Per Hoffmann, Glen Kristiansen, Manel B. Esteller, Hubert Schorle

PLoS Genet. 2015 Jul; 11(7): e1005415. Published online 2015 Jul 30. doi: 10.1371/journal.pgen.1005415

PMCID:: PMC4520454

Abstract Article PDF–5.1M

Select item 442367516.

Activin/Nodal Signaling Switches the Terminal Fate of Human Embryonic Stem Cell-derived Trophoblasts

Prasenjit Sarkar, Shan M. Randall, Timothy S. Collier, Anthony Nero, Teal A. Russell, David C. Muddiman, Balaji M. Rao

J Biol Chem. 2015 Apr 3; 290(14): 8834–8848. Published online 2015 Feb 10. doi: 10.1074/jbc.M114.620641

PMCID:: PMC4423675

Abstract Article PDF–5.2M

Select item 431024417.

Nodal signaling promotes a tumorigenic phenotype in human breast cancer

Gina Kirsammer, Luigi Strizzi, Naira V. Margaryan, Alina Gilgur, Matthew Hyser, Janis Atkinson, Dawn A. Kirschmann, Elisabeth A. Seftor, Mary J.C. Hendrix

Semin Cancer Biol. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: Semin Cancer Biol. 2014 Dec; 29: 40–50. Published online 2014 Jul 26. doi: 10.1016/j.semcancer.2014.07.007