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Select item 110142781.

Nucleolar detention of NONO shields DNA double-strand breaks from aberrant transcripts

Barbara Trifault, Victoria Mamontova, Giacomo Cossa, Sabina Ganskih, Yuanjie Wei, Julia Hofstetter, Pranjali Bhandare, Apoorva Baluapuri, Blanca Nieto, Daniel Solvie, Carsten P Ade, Peter Gallant, Elmar Wolf, Dorthe H Larsen, Mathias Munschauer, Kaspar Burger

Nucleic Acids Res. 2024 Apr 12; 52(6): 3050–3068. Published online 2024 Jan 15. doi: 10.1093/nar/gkae022

PMCID:: PMC11014278

Abstract Article PDF–2.6M

Select item 90211922.

The caspase-2 substrate p54nrb exhibits a multifaceted role in tumor cell death susceptibility via gene regulatory functions

Madeleine Eichler, Ute Distler, Usman Nasrullah, Aswini Krishnan, Manuel Kaulich, Koraljka Husnjak, Wolfgang Eberhardt, Krishnaraj Rajalingam, Stefan Tenzer, Josef Pfeilschifter, Gergely Imre

Cell Death Dis. 2022 Apr; 13(4): 386. Published online 2022 Apr 20. doi: 10.1038/s41419-022-04829-2

PMCID:: PMC9021192

Abstract Article PDF–2.6M

Select item 82115633.

Nuclear scaffold protein p54^nrb/NONO facilitates the hypoxia-enhanced progression of hepatocellular carcinoma

Mengqin Shen, Ruixue Zhang, Wenzhi Jia, Zongping Zhu, Xiaoping Zhao, Li Zhao, Gang Huang, Jianjun Liu

Oncogene. 2021; 40(24): 4167–4183. Published online 2021 Jun 2. doi: 10.1038/s41388-021-01848-9

PMCID:: PMC8211563

Abstract Article PDF–8.1M

Select item 59839304.

Downregulation of NONO induces apoptosis, suppressing growth and invasion in esophageal squamous cell carcinoma

Rui Cheng, Shengtao Zhu, Shuilong Guo, Li Min, Jie Xing, Qingdong Guo, Peng Li, Shutian Zhang

Oncol Rep. 2018 Jun; 39(6): 2575–2583. Published online 2018 Mar 27. doi: 10.3892/or.2018.6334

PMCID:: PMC5983930

Abstract Article PDF–999K

Select item 51100685.

Intellectual disability and non-compaction cardiomyopathy with a de novo NONO mutation identified by exome sequencing

Eyal Reinstein, Shay Tzur, Rony Cohen, Concetta Bormans, Doron M Behar

Eur J Hum Genet. 2016 Nov; 24(11): 1635–1638. Published online 2016 Jun 22. doi: 10.1038/ejhg.2016.72

PMCID:: PMC5110068

Abstract Article PDF–478K

Select item 50381976.

A crystallographic study of human NONO (p54^nrb): overcoming pathological problems with purification, data collection and noncrystallographic symmetry

Gavin J. Knott, Santosh Panjikar, Andrea Thorn, Archa H. Fox, Maria R. Conte, Mihwa Lee, Charles S. Bond

Acta Crystallogr D Struct Biol. 2016 Jun 1; 72(Pt 6): 761–769. Published online 2016 May 25. doi: 10.1107/S2059798316005830

PMCID:: PMC5038197

Abstract Article PDF–1.7M

Select item 44978447.

Characterization of DNA binding and pairing activities associated with the native SFPQ•NONO DNA repair protein complex

Durga Udayakumar, William S. Dynan

Biochem Biophys Res Commun. Author manuscript; available in PMC 2016 Aug 7.

Published in final edited form as: Biochem Biophys Res Commun. 2015 Aug 7; 463(4): 473–478. Published online 2015 May 18. doi: 10.1016/j.bbrc.2015.05.024

PMCID:: PMC4497844

Abstract Article PDF–1022K

Select item 43555408.

p54^nrb/NONO Regulates Cyclic AMP-Dependent Glucocorticoid Production by Modulating Phosphodiesterase mRNA Splicing and Degradation

Jia Yang Lu, Marion B. Sewer

Mol Cell Biol. 2015 Apr; 35(7): 1223–1237. Prepublished online 2015 Jan 20. Published online 2015 Mar 10. doi: 10.1128/MCB.00993-14

PMCID:: PMC4355540

Abstract Article PDF–3.9M

Select item 36814749.

Glucocorticoid Induction of Occludin Expression and Endothelial Barrier Requires Transcription Factor p54 NONO

Jason M. Keil, Xuwen Liu, David A. Antonetti

Invest Ophthalmol Vis Sci. 2013 Jun; 54(6): 4007–4015. Published online 2013 Jun 12. doi: 10.1167/iovs.13-11980

PMCID:: PMC3681474

Abstract Article PDF–603K

Select item 39424110.

p54^nrb associates with the 5′ splice site within large transcription/splicing complexes

Sei Kameoka, Paula Duque, Maria M Konarska

EMBO J. 2004 Apr 21; 23(8): 1782–1791. Published online 2004 Apr 1. doi: 10.1038/sj.emboj.7600187

PMCID:: PMC394241

Abstract Article PDF–348K

Select item 31000911.

Purification and cDNA cloning of HeLa cell p54nrb, a nuclear protein with two RNA recognition motifs and extensive homology to human splicing factor PSF and Drosophila NONA/BJ6.

B Dong, D S Horowitz, R Kobayashi, A R Krainer

Nucleic Acids Res. 1993 Aug 25; 21(17): 4085–4092. doi: 10.1093/nar/21.17.4085

PMCID:: PMC310009

Summary Page Browse PDF–1.7M

Select item 5983812.

Immunodetection of nmt55/p54^nrb isoforms in human breast cancer

Matthew Pavao, Yue-Hua Huang, Laurie J Hafer, Robert B Moreland, Abdulmaged M Traish

BMC Cancer. 2001; 1: 15. Published online 2001 Oct 29. doi: 10.1186/1471-2407-1-15

PMCID:: PMC59838

Abstract Article PDF–633K

Select item 1029433513.

Non-POU Domain-Containing Octomer-Binding (NONO) protein expression and stability promotes the tumorigenicity and activation of Akt/MAPK/β-catenin pathways in human breast cancer cells

Bilal Ahmad Lone, Fouzia Siraj, Ira Sharma, Shweta Verma, Shibendra Kumar Lal Karna, Faiz Ahmad, Preeti Nagar, Chetana Sachidanandan, Yuba Raj Pokharel

Cell Commun Signal. 2023; 21: 157. Published online 2023 Jun 27. doi: 10.1186/s12964-023-01179-0

PMCID:: PMC10294335

Abstract Article PDF–11M

Select item 933051614.

Targeting the splicing factor NONO inhibits GBM progression through GPX1 intron retention

Xu Wang, Mingzhi Han, Shuai Wang, Yanfei Sun, Wenbo Zhao, Zhiyi Xue, Xiangjun Liang, Bin Huang, Gang Li, Anjing Chen, Xingang Li, Jian Wang

Theranostics. 2022; 12(12): 5451–5469. Published online 2022 Jul 11. doi: 10.7150/thno.72248

PMCID:: PMC9330516

Abstract Article PDF–4.3M

Select item 932480315.

Molecular Modelling of NONO and SFPQ Dimerization Process and RNA Recognition Mechanism

Tommaso Laurenzi, Luca Palazzolo, Elisa Taiana, Simona Saporiti, Omar Ben Mariem, Uliano Guerrini, Antonino Neri, Ivano Eberini

Int J Mol Sci. 2022 Jul; 23(14): 7626. Published online 2022 Jul 10. doi: 10.3390/ijms23147626

PMCID:: PMC9324803

Abstract Article PDF–4.8M

Select item 874869116.

RNA-binding protein p54^nrb/NONO potentiates nuclear EGFR-mediated tumorigenesis of triple-negative breast cancer

Mengqin Shen, Ruixue Zhang, Wenzhi Jia, Zongping Zhu, Li Zhao, Gang Huang, Jianjun Liu

Cell Death Dis. 2022 Jan; 13(1): 42. Published online 2022 Jan 10. doi: 10.1038/s41419-021-04488-9

PMCID:: PMC8748691

Abstract Article PDF–6.3M

Select item 846404017.

Transcriptional silencing of fetal hemoglobin expression by NonO

Xinyu Li, Mengxia Chen, Biru Liu, Peifen Lu, Xiang Lv, Xiang Zhao, Shuaiying Cui, Peipei Xu, Yukio Nakamura, Ryo Kurita, Bing Chen, David C S Huang, De-Pei Liu, Ming Liu, Quan Zhao

Nucleic Acids Res. 2021 Sep 27; 49(17): 9711–9723. Published online 2021 Aug 11. doi: 10.1093/nar/gkab671

PMCID:: PMC8464040

Abstract Article PDF–1.9M

Select item 787590718.

The regulation of NONO by USP11 via deubiquitination is linked to the proliferation of melanoma cells

Peifu Feng, Ling Li, Jing Dai, Lingli Zhou, Jing Liu, Jinfeng Zhao, Xiaodong Li, Neng Ling, Siyuan Qiu, Lin Zhang, Tiantian Xie, Yinglei Chen, Michael J. Donovan, Tianhuan Peng, Jianhui Song, Mao Ye

J Cell Mol Med. 2021 Feb; 25(3): 1507–1517. Published online 2020 Dec 25. doi: 10.1111/jcmm.16243

PMCID:: PMC7875907

Abstract Article PDF–1.5M

Select item 744751119.

Paraspeckle components NONO and PSPC1 are not mislocalized from motor neuron nuclei in sporadic ALS

Giulia E Tyzack, Giulia Manferrari, Jia Newcombe, Nicholas M Luscombe, Raphaelle Luisier, Rickie Patani

Brain. 2020 Aug; 143(8): e66. Published online 2020 Aug 10. doi: 10.1093/brain/awaa205

PMCID:: PMC7447511

Article PDF–472K

Select item 738174420.

RNA-binding protein NONO contributes to cancer cell growth and confers drug resistance as a theranostic target in TNBC

Seong-Jin Kim, Jin-Sung Ju, Myoung-Hee Kang, Ji Eun Won, Young Ha Kim, Prahlad V Raninga, Kum Kum Khanna, Balázs Győrffy, Chan-Gi Pack, Hee-Dong Han, Hee Jin Lee, Gyungyub Gong, Yong Shin, Gordon B. Mills, Seong-il Eyun, Yun-Yong Park

Theranostics. 2020; 10(18): 7974–7992. Published online 2020 Jul 2. doi: 10.7150/thno.45037

PMCID:: PMC7381744

Abstract Article PDF–5.4M

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PMC Links for Gene (Select 4841) (287)
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PREDICTED: Homo sapiens UDP glycosyltransferase family 3 member A1 (UGT3A1), tra...
PREDICTED: Homo sapiens UDP glycosyltransferase family 3 member A1 (UGT3A1), transcript variant X5, mRNA
gi|2217354395|ref|XM_005248243.5|

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