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Select item 105794721.

Biallelic NPR1 loss of function variants are responsible for neonatal systemic hypertension

Yline Capri, Theresa Kwon, Olivia Boyer, Lucas Bourmance, Noe Testa, Véronique Baudouin, Ronan Bonnefoy, Anne Couderc, Chakib Meziane, Elisabeth Tournier-Lasserve, Laurence Heidet, Judith Melki

J Med Genet. 2023 Oct; 60(10): 993–998. Published online 2023 Apr 20. doi: 10.1136/jmg-2023-109176

PMCID:: PMC10579472

Abstract Article PDF–696K

Select item 87198542.

Discovery of small molecule guanylyl cyclase A receptor positive allosteric modulators

S. Jeson Sangaralingham, Kanupriya Whig, Satyamaheshwar Peddibhotla, R. Jason Kirby, Hampton E. Sessions, Patrick R. Maloney, Paul M. Hershberger, Heather Mose-Yates, Becky L. Hood, Stefan Vasile, Shuchong Pan, Ye Zheng, Siobhan Malany, John C. Burnett, Jr.

Proc Natl Acad Sci U S A. 2021 Dec 28; 118(52): e2109386118. Published online 2021 Dec 20. doi: 10.1073/pnas.2109386118

PMCID:: PMC8719854

Abstract Article PDF–1.5M

Select item 85288243.

Natriuretic peptide receptor a promotes gastric malignancy through angiogenesis process

Zheng Li, Hao Fan, Jiacheng Cao, Guangli Sun, Sen Wang, Jialun Lv, Zhe Xuan, Yiwen Xia, Linjun Wang, Diancai Zhang, Hao Xu, Zekuan Xu

Cell Death Dis. 2021 Nov; 12(11): 968. Published online 2021 Oct 20. doi: 10.1038/s41419-021-04266-7

PMCID:: PMC8528824

Abstract Article PDF–5.2M

Select item 46268694.

Subcellular trafficking of guanylyl cyclase/natriuretic peptide receptor-A with concurrent generation of intracellular cGMP

Indra Mani, Renu Garg, Satyabha Tripathi, Kailash N. Pandey

Biosci Rep. 2015 Oct; 35(5): e00260. Prepublished online 2015 Sep 15. Published online 2015 Oct 30. doi: 10.1042/BSR20150136

PMCID:: PMC4626869

Abstract Article PDF–1.9M

Select item 43218885.

Common variations in noncoding regions of the human natriuretic peptide receptor A gene have quantitative effects

Joshua W. Knowles, Laurie M. Erickson, Vanessa K. Guy, Carlie S. Sigel, Jennifer C. Wilder, Nobuyo Maeda

Hum Genet. Author manuscript; available in PMC 2015 Feb 9.

Published in final edited form as: Hum Genet. 2003 Jan; 112(1): 62–70. Published online 2002 Oct 10. doi: 10.1007/s00439-002-0834-z

PMCID:: PMC4321888

Abstract Article PDF–531K

Select item 40383706.

Expression of natriuretic peptide receptor-A in esophageal squamous cell carcinomas and the relationship with tumor invasion and migration

Zhilong Zhao, Haoqian Liu, Ya Yang, Kai Sun, Min Li, Jia Zhang, Hui Cai, Jiansheng Wang

World J Surg Oncol. 2014; 12: 154. Published online 2014 May 21. doi: 10.1186/1477-7819-12-154

PMCID:: PMC4038370

Abstract Article PDF–1.7M

Select item 31217147.

Natriuretic Peptide Receptor A as a Novel Target for Prostate Cancer

Xiaoqin Wang, Payal Raulji, Shyam S Mohapatra, Ronil Patel, Gary Hellermann, Xiaoyuan Kong, Pedro L Vera, Katherine L Meyer-Siegler, Domenico Coppola, Subhra Mohapatra

Mol Cancer. 2011; 10: 56. Published online 2011 May 17. doi: 10.1186/1476-4598-10-56

PMCID:: PMC3121714

Abstract Article PDF–1.5M

Select item 30972968.

The Functional Genomics of Guanylyl Cyclase/Natriuretic Peptide Receptor-A: Perspectives and Paradigms

Kailash N. Pandey

FEBS J. Author manuscript; available in PMC 2012 Jun 1.

Published in final edited form as: FEBS J. 2011 Jun; 278(11): 1792–1807. Published online 2011 Apr 7. doi: 10.1111/j.1742-4658.2011.08081.x

PMCID:: PMC3097296

Abstract Article PDF–614K

Select item 4009649.

Human atrial natriuretic peptide receptor defines a new paradigm for second messenger signal transduction.

D G Lowe, M S Chang, R Hellmiss, E Chen, S Singh, D L Garbers, D V Goeddel

EMBO J. 1989 May; 8(5): 1377–1384. doi: 10.1002/j.1460-2075.1989.tb03518.x

PMCID:: PMC400964

Summary Page Browse PDF–1.7M

Select item 941422210.

The pseudokinase domains of guanylyl cyclase–A and –B allosterically increase the affinity of their catalytic domains for substrate

Aaron B. Edmund, Timothy F. Walseth, Nicholas M. Levinson, Lincoln R. Potter

Sci Signal. Author manuscript; available in PMC 2022 Aug 26.

Published in final edited form as: Sci Signal. 2019 Jan 29; 12(566): eaau5378. Published online 2019 Jan 29. doi: 10.1126/scisignal.aau5378

PMCID:: PMC9414222

Abstract Article PDF–4.0M

Select item 629311511.

Molecular and genetic aspects of guanylyl cyclase natriuretic peptide receptor-A in regulation of blood pressure and renal function

Kailash N. Pandey

Physiol Genomics. 2018 Nov 1; 50(11): 913–928. Published online 2018 Aug 31. doi: 10.1152/physiolgenomics.00083.2018

PMCID:: PMC6293115

Abstract Article

Select item 441139812.

Guanylyl Cyclases A and B Are Asymmetric Dimers That Are Allosterically Activated by ATP Binding to the Catalytic Domain

Jerid W. Robinson, Lincoln R. Potter

Sci Signal. Author manuscript; available in PMC 2015 Apr 28.

Published in final edited form as: Sci Signal. 2012 Sep 4; 5(240): ra65. Published online 2012 Sep 4. doi: 10.1126/scisignal.2003253

PMCID:: PMC4411398

Abstract Article PDF–1.7M

Select item 406704213.

Guanylyl cyclase (GC)-A and GC-B activities in ventricles and cardiomyocytes from failed and non-failed human hearts: GC-A is inactive in the failed cardiomyocyte

Deborah M. Dickey, Daniel L. Dries, Kenneth B. Margulies, Lincoln R. Potter

J Mol Cell Cardiol. Author manuscript; available in PMC 2014 Jun 23.

Published in final edited form as: J Mol Cell Cardiol. 2012 Mar; 52(3): 727–732. Published online 2011 Nov 22. doi: 10.1016/j.yjmcc.2011.11.007

PMCID:: PMC4067042

Abstract Article PDF–392K

Select item 319078014.

ATP Potentiates Competitive Inhibition of Guanylyl Cyclase A and B by the Staurosporine Analog, Gö6976: RECIPROCAL REGULATION OF ATP AND GTP BINDING

Jerid W. Robinson, Lincoln R. Potter

J Biol Chem. 2011 Sep 30; 286(39): 33841–33844. Published online 2011 Aug 2. doi: 10.1074/jbc.M111.273565

PMCID:: PMC3190780

Abstract Article PDF–855K

Select item 262969515.

Investigation of the Association between Normal-tension Glaucoma and Single Nucleotide Polymorphisms in Natriuretic Peptide Gene

Jin Wook Jeoung, Dong Myung Kim, Hyun Soo Ko, Sung Sup Park, Ji Yeon Kim, Sung Yeun Kim, Tai Woo Yoo

Korean J Ophthalmol. 2007 Mar; 21(1): 33–38. Published online 2007 Mar 20. doi: 10.3341/kjo.2007.21.1.33

PMCID:: PMC2629695

Abstract Article PDF–445K

Select item 12145516.

Phosphorylation of the Kinase Homology Domain Is Essential for Activation of the A-Type Natriuretic Peptide Receptor

Lincoln R. Potter, Tony Hunter

Mol Cell Biol. 1998 Apr; 18(4): 2164–2172. doi: 10.1128/mcb.18.4.2164

PMCID:: PMC121455

Abstract Article PDF–1.2M

Select item 779278717.

ANP and BNP Exert Anti-Inflammatory Action via NPR-1/cGMP Axis by Interfering with Canonical, Non-Canonical, and Alternative Routes of Inflammasome Activation in Human THP1 Cells

Letizia Mezzasoma, Vincenzo Nicola Talesa, Rita Romani, Ilaria Bellezza

Int J Mol Sci. 2021 Jan; 22(1): 24. Published online 2020 Dec 22. doi: 10.3390/ijms22010024

PMCID:: PMC7792787

Abstract Article PDF–3.6M

Select item 415795518.

Cardiac Fibrosis in End-Stage Human Heart Failure and the Cardiac Natriuretic Peptide Guanylyl Cyclase System: Regulation and Therapeutic Implications

Tomoko Ichiki, John A Schirger, Brenda K Huntley, Frank C Brozovich, Josef J Maleszewski, Sharon M Sandberg, S Jeson Sangaralingham, Soon J Park, John C Burnett, Jr

J Mol Cell Cardiol. Author manuscript; available in PMC 2015 Oct 1.

Published in final edited form as: J Mol Cell Cardiol. 2014 Oct; 75: 199–205. Published online 2014 Aug 9. doi: 10.1016/j.yjmcc.2014.08.001