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Select item 34032971.

Nardilysin and ADAM proteases promote gastric cancer cell growth by activating intrinsic cytokine signalling via enhanced ectodomain shedding of TNF-α

Keitaro Kanda, Hideyuki Komekado, Tateo Sawabu, Shoko Ishizu, Yuki Nakanishi, Masato Nakatsuji, Reiko Akitake-Kawano, Mikiko Ohno, Yoshinori Hiraoka, Mayumi Kawada, Kenji Kawada, Yoshiharu Sakai, Kyoichi Matsumoto, Makoto Kunichika, Takeshi Kimura, Hiroshi Seno, Eiichiro Nishi, Tsutomu Chiba

EMBO Mol Med. 2012 May; 4(5): 396–411. doi: 10.1002/emmm.201200216

PMCID:: PMC3403297

Abstract Article PDF–907K

Select item 26602612.

Nardilysin convertase regulates the function of the maxi-K channel isoform mK44 in human myometrium

Victoria P. Korovkina, Susan J. Stamnes, Adam M. Brainard, Sarah K. England

Am J Physiol Cell Physiol. 2009 Mar; 296(3): C433–C440. Published online 2008 Dec 31. doi: 10.1152/ajpcell.00357.2008

PMCID:: PMC2660261

Abstract Article

Select item 12228703.

The metalloendopeptidase nardilysin (NRDc) is potently inhibited by heparin-binding epidermal growth factor-like growth factor (HB-EGF).

Véronique Hospital, Eiichiro Nishi, Michael Klagsbrun, Paul Cohen, Nabil G Seidah, Annik Prat

Biochem J. 2002 Oct 1; 367(Pt 1): 229–238. doi: 10.1042/BJ20020822

PMCID:: PMC1222870

Summary PDF–358K

Select item 12214164.

Gene expression of the dibasic-pair cleaving enzyme NRD convertase (N-arginine dibasic convertase) is differentially regulated in the GH3 pituitary and Mat-Lu prostate cell lines.

A G Winter, A R Pierotti

Biochem J. 2000 Nov 1; 351(Pt 3): 755–764.

PMCID:: PMC1221416

Summary PDF–283K

Select item 12188565.

Human and rat testis express two mRNA species encoding variants of NRD convertase, a metalloendopeptidase of the insulinase family.

V Hospital, A Prat, C Joulie, D Chérif, R Day, P Cohen

Biochem J. 1997 Nov 1; 327(Pt 3): 773–779. doi: 10.1042/bj3270773

PMCID:: PMC1218856

Summary PDF–438K

Select item 1255256.

N-arginine dibasic convertase is a specific receptor for heparin-binding EGF-like growth factor that mediates cell migration

Eiichiro Nishi, Annik Prat, Véronique Hospital, Klaus Elenius, Michael Klagsbrun

EMBO J. 2001 Jul 2; 20(13): 3342–3350. doi: 10.1093/emboj/20.13.3342

PMCID:: PMC125525

Abstract Article PDF–269K

Select item 43178827.

NRD1, which encodes nardilysin protein, promotes esophageal cancer cell invasion through induction of MMP2 and MMP3 expression

Naohiro Uraoka, Naohide Oue, Naoya Sakamoto, Kazuhiro Sentani, Htoo Zarni Oo, Yutaka Naito, Tsuyoshi Noguchi, Wataru Yasui

Cancer Sci. 2014 Jan; 105(1): 134–140. Published online 2013 Nov 29. doi: 10.1111/cas.12316

PMCID:: PMC4317882

Abstract Article PDF–1.2M

Select item 39260108.

Critical roles of nardilysin in the maintenance of body temperature homoeostasis

Yoshinori Hiraoka, Tatsuhiko Matsuoka, Mikiko Ohno, Kazuhiro Nakamura, Sayaka Saijo, Shigenobu Matsumura, Kiyoto Nishi, Jiro Sakamoto, Po-Min Chen, Kazuo Inoue, Tohru Fushiki, Toru Kita, Takeshi Kimura, Eiichiro Nishi

Nat Commun. 2014 Feb 4; 5: 3224. Published online 2014 Feb 4. doi: 10.1038/ncomms4224

PMCID:: PMC3926010

Abstract Article PDF–2.1M

Select item 33230439.

Identification and Characterization of Nardilysin as a Novel Dimethyl H3K4-binding Protein Involved in Transcriptional Regulation

Jing Li, Mingyue Chu, Shanshan Wang, Doug Chan, Shankang Qi, Meng Wu, Zhongliang Zhou, Jiwen Li, Eiichiro Nishi, Jun Qin, Jiemin Wong

J Biol Chem. 2012 Mar 23; 287(13): 10089–10098. Published online 2012 Jan 30. doi: 10.1074/jbc.M111.313965

PMCID:: PMC3323043

Abstract Article PDF–1.6M

Select item 338878510.

Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasion

Cynthia R Coffill, Patricia A J Muller, Hue Kian Oh, Suat Peng Neo, Kelly A Hogue, Chit Fang Cheok, Karen H Vousden, David P Lane, Walter P Blackstock, Jayantha Gunaratne

EMBO Rep. 2012 Jul; 13(7): 638–644. Published online 2012 Jun 1. doi: 10.1038/embor.2012.74

PMCID:: PMC3388785

Abstract Article PDF–687K

Select item 52278511.

Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV

Christine Anne Koch, Roger Agyei, Sarah Galicia, Pavel Metalnikov, Paul O'Donnell, Andrei Starostine, Michael Weinfeld, Daniel Durocher

EMBO J. 2004 Sep 29; 23(19): 3874–3885. Published online 2004 Sep 23. doi: 10.1038/sj.emboj.7600375

PMCID:: PMC522785

Abstract Article PDF–271K

Select item 524214212.

Loss of Nardilysin, a mitochondrial co-chaperone for α-Ketoglutarate Dehydrogenase, promotes mTORC1 activation and neurodegeneration

Wan Hee Yoon, Hector Sandoval, Sonal Nagarkar-Jaiswal, Manish Jaiswal, Shinya Yamamoto, Nele A. Haelterman, Nagireddy Putluri, Vasanta Putluri, Arun Sreekumar, Tulay Tos, Ayse Aksoy, Taraka Donti, Brett H. Graham, Mikiko Ohno, Eiichiro Nishi, Jill Hunter, Donna M. Muzny, Jason Carmichael, Joseph Shen, Valerie A. Arboleda, Stanley F. Nelson, Michael F. Wangler, Ender Karaca, James R. Lupski, Hugo J. Bellen

Neuron. Author manuscript; available in PMC 2018 Jan 4.

Published in final edited form as: Neuron. 2017 Jan 4; 93(1): 115–131. Published online 2016 Dec 22. doi: 10.1016/j.neuron.2016.11.038

PMCID:: PMC5242142

Abstract Article PDF–2.2M

Select item 429537513.

Substrate Trapping Proteomics Reveals Targets of the βTrCP2/FBXW11 Ubiquitin Ligase

Tai Young Kim, Priscila F. Siesser, Kent L. Rossman, Dennis Goldfarb, Kathryn Mackinnon, Feng Yan, XianHua Yi, Michael J. MacCoss, Randall T. Moon, Channing J. Der, Michael B. Major

Mol Cell Biol. 2015 Jan; 35(1): 167–181. Prepublished online 2014 Oct 20. Published online 2014 Dec 9. doi: 10.1128/MCB.00857-14

PMCID:: PMC4295375

Abstract Article PDF–5.6M

Select item 492871614.

HIV–host interactome revealed directly from infected cells

Yang Luo, Erica Y. Jacobs, Todd M. Greco, Kevin D. Mohammed, Tommy Tong, Sarah Keegan, James M. Binley, Ileana M. Cristea, David Fenyö, Michael P. Rout, Brian T. Chait, Mark A. Muesing

Nat Microbiol. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: Nat Microbiol. 2016 Jul; 1(7): 16068. Published online 2016 May 23. doi: 10.1038/nmicrobiol.2016.68

PMCID:: PMC4928716

Abstract Article PDF–1.1M

Select item 791045915.

Combinatorial CRISPR screen identifies fitness effects of gene paralogues

Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams

Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9

PMCID:: PMC7910459

Abstract Article PDF–3.3M

Select item 332257716.

Host Cell Interactome of HIV-1 Rev Includes RNA Helicases Involved in Multiple Facets of Virus Production

Souad Naji, Géza Ambrus, Peter Cimermančič, Jason R. Reyes, Jeffrey R. Johnson, Rebecca Filbrandt, Michael D. Huber, Paul Vesely, Nevan J. Krogan, John R. Yates, III, Andrew C. Saphire, Larry Gerace

Mol Cell Proteomics. 2012 Apr; 11(4): M111.015313. Published online 2011 Dec 15. doi: 10.1074/mcp.M111.015313

PMCID:: PMC3322577

Abstract Article PDF–1.4M

Select item 794896417.

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1

Lee D. Harris, Janic Le Pen, Nico Scholz, Juliusz Mieszczanek, Natalie Vaughan, Simon Davis, Georgina Berridge, Benedikt M. Kessler, Mariann Bienz, Julien D.F. Licchesi

J Biol Chem. 2021 Jan-Jun; 296: 100246. Published online 2021 Jan 8. doi: 10.1074/jbc.RA120.015162

PMCID:: PMC7948964

Abstract Article PDF–2.7M

Select item 729913018.

IKK-mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5

Jingzi Zhang, Ruoyu Zhao, Christine L. N. Bryant, Kenneth Wu, Zhihong Liu, Yibing Ding, Yue Zhao, Bin Xue, Zhen-Qiang Pan, Chaojun Li, Lan Huang, Lei Fang

J Proteome Res. Author manuscript; available in PMC 2020 Jun 17.

Published in final edited form as: J Proteome Res. 2020 Mar 6; 19(3): 1119–1130. Published online 2020 Feb 3. doi: 10.1021/acs.jproteome.9b00626

PMCID:: PMC7299130

Abstract Article PDF–2.2M

Select item 458732619.

BioID-based Identification of Skp Cullin F-box (SCF)^β-TrCP1/2 E3 Ligase Substrates

Etienne Coyaud, Monika Mis, Estelle M. N. Laurent, Wade H. Dunham, Amber L. Couzens, Melanie Robitaille, Anne-Claude Gingras, Stephane Angers, Brian Raught

Mol Cell Proteomics. 2015 Jul; 14(7): 1781–1795. Published online 2015 Apr 21. doi: 10.1074/mcp.M114.045658

PMCID:: PMC4587326

Abstract Article PDF–3.7M

Select item 959735220.

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes

Shalini Rawat, Dhruba Chatterjee, Rituraj Marwaha, Gitanjali Charak, Gaurav Kumar, Shrestha Shaw, Divya Khatter, Sheetal Sharma, Cecilia de Heus, Nalan Liv, Judith Klumperman, Amit Tuli, Mahak Sharma

J Cell Biol. 2023 Jan 2; 222(1): e202108001. Published online 2022 Oct 25. doi: 10.1083/jcb.202108001

PMCID:: PMC9597352

Abstract Article PDF–12M

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