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Items: 1 to 20 of 49

1.
PCSK6 and Survival in Idiopathic Pulmonary Fibrosis
Justin M. Oldham, Richard J. Allen, Jose M. Lorenzo-Salazar, Philip L. Molyneaux, Shwu-Fan Ma, Chitra Joseph, John S. Kim, Beatriz Guillen-Guio, Tamara Hernández-Beeftink, Jonathan A. Kropski, Yong Huang, Cathryn T. Lee, Ayodeji Adegunsoye, Janelle Vu Pugashetti, Angela L. Linderholm, Vivian Vo, Mary E. Strek, Jonathan Jou, Adrian Muñoz-Barrera, Luis A. Rubio-Rodriguez, Richard Hubbard, Nik Hirani, Moira K. B. Whyte, Simon Hart, Andrew G. Nicholson, Lisa Lancaster, Helen Parfrey, Doris Rassl, William Wallace, Eleanor Valenzi, Yingze Zhang, Josyf Mychaleckyj, Amy Stockwell, Naftali Kaminski, Paul J. Wolters, Maria Molina-Molina, Nicholas E. Banovich, William A. Fahy, Fernando J. Martinez, Ian P. Hall, Martin D. Tobin, Toby M. Maher, Timothy S. Blackwell, Brian L. Yaspan, R. Gisli Jenkins, Carlos Flores, Louise V. Wain, Imre Noth
Am J Respir Crit Care Med. 2023 Jun 1; 207(11): 1515–1524. Published online 2023 Feb 13. doi: 10.1164/rccm.202205-0845OC
PMCID:
PMC10263132
AbstractArticlePDF–1.4M
2.
Paired Basic Amino Acid-cleaving Enzyme 4 (PCSK6): An Emerging New Target Molecule in Human Melanoma
Carsten WEISHAUPT, Arianna MASTROFRANCESCO, Dieter METZE, Björn KEMPER, Agatha STEGEMANN, Mauro PICARDO, Andres J. P. KLEIN-SZANTO, Markus BÖHM
Acta Derm Venereol. 2020; 100(10): 5779. Published online 2020 May 29. doi: 10.2340/00015555-3525
PMCID:
PMC9137352
AbstractArticlePDF–9.4M
3.
PACE4-altCT isoform of proprotein convertase PACE4 as tissue and plasmatic biomarker for prostate cancer
Frédéric Couture, Luojun Wang, Frédérik Dufour, Keena Chabot-Maheux, Nadia Ekindi Ndongo, Robert Sabbagh, Robert Day
Sci Rep. 2022; 12: 6066. Published online 2022 Apr 11. doi: 10.1038/s41598-022-09778-6
PMCID:
PMC9001653
AbstractArticlePDF–2.9M
4.
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways
Zhiyong Yao, Bin Sun, Quan Hong, Jingmin Yan, Dawei Mu, Jianye Li, Haibo Sheng, Heqing Guo
Drug Des Devel Ther. 2015; 9: 5911–5923. Published online 2015 Nov 5. doi: 10.2147/DDDT.S86881
PMCID:
PMC4639519
AbstractArticlePDF–2.2M
5.
Multi-Leu PACE4 Inhibitor Retention within Cells Is PACE4 Dependent and a Prerequisite for Antiproliferative Activity
Frédéric Couture, Kévin Ly, Christine Levesque, Anna Kwiatkowska, Samia Ait-Mohand, Roxane Desjardins, Brigitte Guérin, Robert Day
Biomed Res Int. 2015; 2015: 824014. Published online 2015 May 31. doi: 10.1155/2015/824014
PMCID:
PMC4465654
AbstractArticlePDF–1.1M
6.
PCSK6 VNTR Polymorphism Is Associated with Degree of Handedness but Not Direction of Handedness
Larissa Arning, Sebastian Ocklenburg, Stefanie Schulz, Vanessa Ness, Wanda M. Gerding, Jan G. Hengstler, Michael Falkenstein, Jörg T. Epplen, Onur Güntürkün, Christian Beste
PLoS One. 2013; 8(6): e67251. Published online 2013 Jun 27. doi: 10.1371/journal.pone.0067251
PMCID:
PMC3695088
AbstractArticlePDF–179K
7.
Role of Proprotein Convertases in Prostate Cancer Progression
Frédéric Couture, François D'Anjou, Roxane Desjardins, François Boudreau, Robert Day
Neoplasia. 2012 Nov; 14(11): 1032–1042. doi: 10.1593/neo.121368
PMCID:
PMC3514743
AbstractArticlePDF–2.3M
8.
PCSK6 is associated with handedness in individuals with dyslexia
Thomas S. Scerri, William M. Brandler, Silvia Paracchini, Andrew P. Morris, Susan M. Ring, Alex J. Richardson, Joel B. Talcott, John Stein, Anthony P. Monaco
Hum Mol Genet. 2011 Feb 1; 20(3): 608–614. Published online 2010 Nov 4. doi: 10.1093/hmg/ddq475
PMCID:
PMC3016905
AbstractArticlePDF–144K
9.
Endoprotease PACE4 is Ca2+-dependent and temperature-sensitive and can partly rescue the phenotype of a furin-deficient cell strain.
J F Sucic, J M Moehring, N M Inocencio, J W Luchini, T J Moehring
Biochem J. 1999 May 1; 339(Pt 3): 639–647.
PMCID:
PMC1220200
SummaryPDF–219K
10.
Up-regulation of microRNA-135 or silencing of PCSK6 attenuates inflammatory response in preeclampsia by restricting NLRP3 inflammasome
Xiaolan Zhao, Xun Zhang, Zhao Wu, Jie Mei, Lingling Li, Yujue Wang
Mol Med. 2021; 27: 82. Published online 2021 Jul 23. doi: 10.1186/s10020-021-00335-x
PMCID:
PMC8299578
AbstractArticlePDF–7.6M
11.
Functional Analysis of Corin Protein Domains Required for PCSK6-mediated Activation
Shenghan Chen, Hao Wang, Heng Li, Yue Zhang, Qingyu Wu
Int J Biochem Cell Biol. Author manuscript; available in PMC 2019 Jan 1.
Published in final edited form as: Int J Biochem Cell Biol. 2018 Jan; 94: 31–39. Published online 2017 Nov 24. doi: 10.1016/j.biocel.2017.11.010
PMCID:
PMC5745258
AbstractArticlePDF–1.5M
12.
The handedness-associated PCSK6 locus spans an intronic promoter regulating novel transcripts
Robert Shore, Laura Covill, Kerry A. Pettigrew, William M. Brandler, Rebeca Diaz, Yiwang Xu, Javier A. Tello, Joel B. Talcott, Dianne F. Newbury, John Stein, Anthony P. Monaco, Silvia Paracchini
Hum Mol Genet. 2016 May 1; 25(9): 1771–1779. Published online 2016 Feb 21. doi: 10.1093/hmg/ddw047
PMCID:
PMC4986331
AbstractArticlePDF–466K
13.
A Role for PACE4 in Osteoarthritis Pain: Evidence from Human Genetic Association and Null Mutant Phenotype
Anne-Marie Malfait, Albert B. Seymour, Feng Gao, Micky D. Tortorella, Marie-Pierre Hellio Le Graverand-Gastineau, Linda S. Wood, Michael Doherty, Sally Doherty, Weiya Zhang, Nigel K. Arden, Frances L. Vaughn, Paul L. Leaverton, Tim D. Spector, Deborah J. Hart, Rose A. Maciewicz, Kenneth R. Muir, Rosalina Das, Robert E. Sorge, Susanna G. Sotocinal, Ara Schorscher-Petcu, Ana M. Valdes, Jeffrey S. Mogil
Ann Rheum Dis. Author manuscript; available in PMC 2013 Jun 1.
Published in final edited form as: Ann Rheum Dis. 2012 Jun; 71(6): 1042–1048. Published online 2012 Mar 22. doi: 10.1136/annrheumdis-2011-200300
PMCID:
PMC3603144
AbstractArticlePDF–1.2M
14.
Subtilisin-like Proprotein Convertase Expression, Localization, and Activity in the Human Retina and Optic Nerve Head
John A. Fuller, Anne-Marie Brun-Zinkernagel, Abbot F. Clark, Robert J. Wordinger
Invest Ophthalmol Vis Sci. Author manuscript; available in PMC 2014 Sep 5.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2009 Dec; 50(12): 5759–5768. Published online 2009 Apr 1. doi: 10.1167/iovs.08-2616
PMCID:
PMC4155744
AbstractArticlePDF–4.0M
15.
Cell-surface processing of extracellular human immunodeficiency virus type 1 Vpr by proprotein convertases
Yong Xiao, Gang Chen, Jonathan Richard, Nicole Rougeau, Hongshan Li, Nabil G. Seidah, Éric A. Cohen
Virology. Author manuscript; available in PMC 2014 Mar 15.
Published in final edited form as: Virology. 2008 Mar 15; 372(2): 384–397. Published online 2007 Dec 3. doi: 10.1016/j.virol.2007.10.036
PMCID:
PMC3955186
AbstractArticlePDF–1.2M
16.
Proprotein convertase PACE4 is down-regulated by the basic helix-loop-helix transcription factor hASH-1 and MASH-1.
I Yoshida, S Koide, S I Hasegawa, A Nakagawara, A Tsuji, Y Matsuda
Biochem J. 2001 Dec 15; 360(Pt 3): 683–689. doi: 10.1042/0264-6021:3600683
PMCID:
PMC1222273
SummaryPDF–245K
17.
PCSK6-mediated corin activation is essential for normal blood pressure
Shenghan Chen, Pengxiu Cao, Ningzheng Dong, Jianhao Peng, Chunyi Zhang, Hao Wang, Tiantian Zhou, Junhua Yang, Yue Zhang, Elizabeth E Martelli, Sathyamangla V Naga Prasad, Rachel E Miller, Anne-Marie Malfait, Yiqing Zhou, Qingyu Wu
Nat Med. Author manuscript; available in PMC 2016 Sep 1.
Published in final edited form as: Nat Med. 2015 Sep; 21(9): 1048–1053. Published online 2015 Aug 10. doi: 10.1038/nm.3920
PMCID:
PMC4710517
AbstractArticlePDF–438K
18.
Cripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturation
Marie-Hélène Blanchet, J Ann Le Good, Daniel Mesnard, Viola Oorschot, Stéphane Baflast, Gabriella Minchiotti, Judith Klumperman, Daniel B Constam
EMBO J. 2008 Oct 8; 27(19): 2580–2591. Published online 2008 Sep 4. doi: 10.1038/emboj.2008.174
PMCID:
PMC2567404
AbstractArticlePDF–1.8M
19.
A proteomic approach reveals transient association of reticulocalbin-3, a novel member of the CREC family, with the precursor of subtilisin-like proprotein convertase, PACE4
Akihiko Tsuji, Yayoi Kikuchi, Yukimi Sato, Shizuyo Koide, Keizo Yuasa, Masami Nagahama, Yoshiko Matsuda
Biochem J. 2006 May 15; 396(Pt 1): 51–59. Prepublished online 2006 Jan 24. Published online 2006 Apr 26. doi: 10.1042/BJ20051524
PMCID:
PMC1449992
AbstractArticlePDF–766K
20.
Comparative cellular processing of the human immunodeficiency virus (HIV-1) envelope glycoprotein gp160 by the mammalian subtilisin/kexin-like convertases.
F Vollenweider, S Benjannet, E Decroly, D Savaria, C Lazure, G Thomas, M Chrétien, N G Seidah
Biochem J. 1996 Mar 1; 314(Pt 2): 521–532. doi: 10.1042/bj3140521
PMCID:
PMC1217081
SummaryPDF–620K

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