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Items: 1 to 20 of 36

1.
IL21R hypomethylation as a biomarker for distinguishing benign and malignant breast tumours
Zishan Zang, Yifei Yin, Chunlan Liu, Qiang Zhu, Xuandong Huang, Hong Li, Rongxi Yang
Epigenetics. 2024; 19(1): 2352683. Published online 2024 May 9. doi: 10.1080/15592294.2024.2352683
PMCID:
PMC11086039
AbstractArticlePDF–2.3M
2.
HIV-1 infection and the lack of viral control are associated with greater expression of interleukin-21 receptor on CD8+ T cells
Jama Dalel, Seng K. Ung, Peter Hayes, S. Lucas Black, Sarah Joseph, Deborah F. King, Julia Makinde, Jill Gilmour
AIDS. 2021 Jul 1; 35(8): 1167–1177. Published online 2021 Mar 11. doi: 10.1097/QAD.0000000000002864
PMCID:
PMC8183476
AbstractArticlePDF–487K
3.
Genomic Spectrum and Phenotypic Heterogeneity of Human IL-21 Receptor Deficiency
Deniz Cagdas, Daniel Mayr, Safa Baris, Lisa Worley, David B. Langley, Ayse Metin, Elif Soyak Aytekin, Raziye Atan, Nurhan Kasap, Sevgi Köstel Bal, Jasmin Dmytrus, Raul Jimenez Heredia, Gulsun Karasu, Selda Hancerli Torun, Muge Toyran, Elif Karakoc-Aydiner, Daniel Christ, Baris Kuskonmaz, Duygu Uçkan-Çetinkaya, Aysegul Uner, Felicitas Oberndorfer, Ana-Iris Schiefer, Gulbu Uzel, Elissa K. Deenick, Baerbel Keller, Klaus Warnatz, Bénédicte Neven, Anne Durandy, Ozden Sanal, Cindy S. Ma, Ahmet Özen, Polina Stepensky, Ilhan Tezcan, Kaan Boztug, Stuart G. Tangye
J Clin Immunol. 2021; 41(6): 1272–1290. Published online 2021 Apr 30. doi: 10.1007/s10875-021-01031-5
PMCID:
PMC8086229
AbstractArticlePDF–1.4M
4.
Interleukin‐21 receptor gene polymorphism is associated with hepatitis B virus‐related hepatocellular carcinoma in Chinese patients
Tangyuheng Liu, Jiajia Song, Mei Zhang, Siyue Li, Jinya Zhang, Xuejiao Hu, Zhenzhen Zhao, Wu Peng, Qian Wu, Hao Bai, Yinyu Li, Xiaojun Lu, Binwu Ying
J Clin Lab Anal. 2019 Jun; 33(5): e22860. Published online 2019 Feb 13. doi: 10.1002/jcla.22860
PMCID:
PMC6595330
AbstractArticlePDF–397K
5.
IL21R expressing CD14+CD16+ monocytes expand in multiple myeloma patients leading to increased osteoclasts
Marina Bolzoni, Domenica Ronchetti, Paola Storti, Gaetano Donofrio, Valentina Marchica, Federica Costa, Luca Agnelli, Denise Toscani, Rosanna Vescovini, Katia Todoerti, Sabrina Bonomini, Gabriella Sammarelli, Andrea Vecchi, Daniela Guasco, Fabrizio Accardi, Benedetta Dalla Palma, Barbara Gamberi, Carlo Ferrari, Antonino Neri, Franco Aversa, Nicola Giuliani
Haematologica. 2017 Apr; 102(4): 773–784. Prepublished online 2017 Jan 5. doi: 10.3324/haematol.2016.153841
PMCID:
PMC5395118
AbstractArticlePDF–2.2M
6.
Endothelial interleukin-21 receptor up-regulation in peripheral artery disease
Tao Wang, Alexis Cunningham, Kevin Houston, Aditya M Sharma, Lingdan Chen, Ayotunde O Dokun, R John Lye, Rosanne Spolski, Warren J Leonard, Brian H Annex
Vasc Med. Author manuscript; available in PMC 2017 Mar 13.
Published in final edited form as: Vasc Med. 2016 Apr; 21(2): 99–104. Published online 2015 Dec 24. doi: 10.1177/1358863X15621798
PMCID:
PMC5347532
AbstractArticlePDF–626K
7.
Extending the clinical and immunological phenotype of human interleukin-21 receptor deficiency
Polina Stepensky, Baerbel Keller, Omar Abuzaitoun, Avraham Shaag, Barak Yaacov, Susanne Unger, Maximilian Seidl, Marta Rizzi, Michael Weintraub, Orly Elpeleg, Klaus Warnatz
Haematologica. 2015 Feb; 100(2): e72–e76. doi: 10.3324/haematol.2014.112508
PMCID:
PMC4803132
ArticlePDF–398K
8.
Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome
Daniel Kotlarz, Natalia Ziętara, Gulbu Uzel, Thomas Weidemann, Christian J. Braun, Jana Diestelhorst, Peter M. Krawitz, Peter N. Robinson, Jochen Hecht, Jacek Puchałka, E. Michael Gertz, Alejandro A. Schäffer, Monica G. Lawrence, Lela Kardava, Dietmar Pfeifer, Ulrich Baumann, Eva-Doreen Pfister, Eric P. Hanson, Axel Schambach, Roland Jacobs, Hans Kreipe, Susan Moir, Joshua D. Milner, Petra Schwille, Stefan Mundlos, Christoph Klein
J Exp Med. 2013 Mar 11; 210(3): 433–443. doi: 10.1084/jem.20111229
PMCID:
PMC3600901
AbstractArticlePDF–2.2M
9.
Interleukin-21 receptor signaling promotes metabolic dysfunction-associated steatohepatitis-driven hepatocellular carcinoma by inducing immunosuppressive IgA+ B cells
Ying Xie, Yu Huang, Zhi-Yong Li, Weihua Jiang, Nan-Xi Shi, Yuanzhi Lu, Guangchao Cao, Zhinan Yin, Xue-Jia Lin
Mol Cancer. 2024; 23: 95. Published online 2024 May 8. doi: 10.1186/s12943-024-02001-2
PMCID:
PMC11077880
AbstractArticlePDF–11M
10.
IL-21 (rs2055979 and rs2221903)/IL-21R (rs3093301) Polymorphism and High Levels of IL-21 Are Associated with Rheumatoid Arthritis in Mexican Patients
Noemi Magdalena Carreño-Saavedra, Itzel Viridiana Reyes-Pérez, Andrea Carolina Machado-Sulbaran, Gloria Esther Martínez-Bonilla, María Guadalupe Ramírez-Dueñas, José Francisco Muñoz-Valle, Valeria Olaya-Valdiviezo, Trinidad García-Iglesias, Erika Aurora Martínez-García, Pedro Ernesto Sánchez-Hernández
Genes (Basel) 2023 Apr; 14(4): 878. Published online 2023 Apr 7. doi: 10.3390/genes14040878
PMCID:
PMC10137781
AbstractArticlePDF–904K
11.
WSB1 and IL21R Genetic Variants Are Involved in Th2 Immune Responses to Ascaris lumbricoides
Valdirene Leão Carneiro, Hugo Bernardino Ferreira da Silva, Gerson de Almeida Queiroz, Rafael Valente Veiga, Pablo Rafael Silveira Oliveira, Norma Vilany Queiroz Carneiro, Anaque de Oliveira Pires, Raimon Rios da Silva, Flavia Sena, Emilia Belitardo, Regina Nascimento, Milca Silva, Cintia Rodrigues Marques, Ryan dos Santos Costa, Neuza Maria Alcantra-Neves, Mauricio L. Barreto, Philip J. Cooper, Camila Alexandrina Figueiredo
Front Immunol. 2021; 12: 622051. Published online 2021 Feb 22. doi: 10.3389/fimmu.2021.622051
PMCID:
PMC7937724
AbstractArticlePDF–1009K
12.
STAT3 mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8+ T cell memory formation and function
Megan L Ives, Cindy S Ma, Umaimainthan Palendira, Anna Chan, Jacinta Bustamante, Stephanie Boisson-Dupuis, Peter D Arkwright, Dan Engelhard, Diana Averbuch, Klaus Magdorf, Joachim Roesler, Jane Peake, Melanie Wong, Stephen Adelstein, Sharon Choo, Joanne M Smart, Martyn A French, David A Fulcher, Matthew C Cook, Capucine Picard, Anne Durandy, Miyuki Tsumura, Masao Kobayashi, Gulbu Uzel, Jean-Laurent Casanova, Stuart G Tangye, Elissa K Deenick
J Allergy Clin Immunol. Author manuscript; available in PMC 2014 Feb 1.
Published in final edited form as: J Allergy Clin Immunol. 2013 Aug; 132(2): 400–11.e9. Published online 2013 Jul 4. doi: 10.1016/j.jaci.2013.05.029
PMCID:
PMC3785237
AbstractArticlePDF–1.9M
13.
Crystal Structure of Interleukin-21 Receptor (IL-21R) Bound to IL-21 Reveals That Sugar Chain Interacting with WSXWS Motif Is Integral Part of IL-21R
Ole J. Hamming, Lishan Kang, Anders Svensson, Jesper L. Karlsen, Henrik Rahbek-Nielsen, Søren R. Paludan, Siv A. Hjorth, Kent Bondensgaard, Rune Hartmann
J Biol Chem. 2012 Mar 16; 287(12): 9454–9460. Published online 2012 Jan 10. doi: 10.1074/jbc.M111.311084
PMCID:
PMC3308775
AbstractArticlePDF–1.3M
14.
Can anti-cyclic citrullinated peptide antibody-negative RA be subdivided into clinical subphenotypes?
Diederik PC De Rooy, Annemiek Willemze, Bart Mertens, Tom WJ Huizinga, Annette HM Van der Helm-van Mil
Arthritis Res Ther. 2011; 13(5): R180. Published online 2011 Oct 27. doi: 10.1186/ar3505
PMCID:
PMC3308115
AbstractArticlePDF–252K
15.
Upregulation of IL-21 Receptor on B Cells and IL-21 Secretion Distinguishes Novel 2009 H1N1 Vaccine Responders from Nonresponders among HIV-Infected Persons on Combination Antiretroviral Therapy
Suresh Pallikkuth, Sudheesh Pilakka Kanthikeel, Sandra Y. Silva, Margaret Fischl, Rajendra Pahwa, Savita Pahwa
J Immunol. Author manuscript; available in PMC 2012 Jun 1.
Published in final edited form as: J Immunol. 2011 Jun 1; 186(11): 6173–6181. Published online 2011 Apr 29. doi: 10.4049/jimmunol.1100264
PMCID:
PMC3170914
AbstractArticlePDF–2.0M
16.
IL21R and PTH May Underlie Variation of Femoral Neck Bone Mineral Density as Revealed by a Genome-wide Association Study
Yan Guo, Li-Shu Zhang, Tie-Lin Yang, Qing Tian, Dong-Hai Xiong, Yu-Fang Pei, Hong-Wen Deng
J Bone Miner Res. 2010 May; 25(5): 1042–1048. Published online 2009 Oct 26. doi: 10.1359/jbmr.091040
PMCID:
PMC3153368
AbstractArticlePDF–120K
17.
A polymorphism within interleukin-21 receptor (IL21R) confers risk for systemic lupus erythematosus
Ryan Webb, Joan T. Merrill, Jennifer A. Kelly, Andrea Sestak, Kenneth M. Kaufman, Carl D. Langefeld, Julie Ziegler, Robert P. Kimberly, Jeffrey C. Edberg, Rosalind Ramsey-Goldman, Michelle Petri, John D. Reveille, Graciela S. Alarcón, Luis M. Vilá, Marta E. Alarcón-Riquelme, Judith A. James, Gary S. Gilkeson, Chaim O. Jacob, Kathy L. Moser, Patrick M. Gaffney, Timothy J. Vyse, Swapan K. Nath, Peter Lipsky, John B. Harley, Amr H. Sawalha
Arthritis Rheum. Author manuscript; available in PMC 2010 Aug 1.
Published in final edited form as: Arthritis Rheum. 2009 Aug; 60(8): 2402–2407. doi: 10.1002/art.24658
PMCID:
PMC2782592
AbstractArticlePDF–656K
18.
Transcriptional Activation of the Interleukin-21 Gene and Its Receptor Gene by Human T-cell Leukemia Virus Type 1 Tax in Human T-cells
Mariko Mizuguchi, Hironobu Asao, Toshifumi Hara, Masaya Higuchi, Masahiro Fujii, Masataka Nakamura
J Biol Chem. 2009 Sep 18; 284(38): 25501–25511. Published online 2009 Jul 17. doi: 10.1074/jbc.M109.010959
PMCID:
PMC2757951
AbstractArticlePDF–1.5M
19.
Interleukin-21 Receptor Gene Induction in Human T Cells Is Mediated by T-Cell Receptor-Induced Sp1 Activity
Zheng Wu, Hyoung-Pyo Kim, Hai-Hui Xue, Hong Liu, Keji Zhao, Warren J. Leonard
Mol Cell Biol. 2005 Nov; 25(22): 9741–9752. doi: 10.1128/MCB.25.22.9741-9752.2005
PMCID:
PMC1280258
AbstractArticlePDF–636K
20.
IL-21/IL-21R inhibit tumor growth and invasion in non-small cell lung cancer cells via suppressing Wnt/β-catenin signaling and PD-L1 expression
Dan Xue, Ping Yang, Qiongying Wei, Xiaoping Li, Lan Lin, Tingyan Lin
Int J Mol Med. 2019 Nov; 44(5): 1697–1706. Published online 2019 Sep 26. doi: 10.3892/ijmm.2019.4354
PMCID:
PMC6777672
AbstractArticlePDF–1.0M

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